IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. Cancer Cell (1535-6108) 2014 imex curation Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu 18-Sep-2014: Contacted by IntAct-Help. Only protein-protein interactions human-sum159pt Human SUM-159PT Anaplastic carcinoma, triple-negative sum-159pt SUM-159PT Anaplastic carcinoma, triple-negative ch-ip chromatin immunoprecipitation assay ch-ip q-pcr quantitative pcr q-pcr Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer There appear to be two results for the gene CHST3 - one results giving ~X2 the result of the other. Mutant entered as a "mutant" rather than "mutation increasing" - as size of WT peak in "negative region" is comparable to size of all other WT peaks. Kornelia_Polyak@dfci.harvard.edu Accepted 2014-AUG-07 by ORCHARD Cancer Cell (1535-6108) 2014 Only protein-protein interactions imex curation JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. Cancer Cell (1535-6108) 2014 imex curation Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu 18-Sep-2014: Contacted by IntAct-Help. Only protein-protein interactions human-cama-1 Human CAMA-1 Breast adenocarcinoma, derived from metastatic site: pleural effusion cama-1 Human CAMA-1 Breast adenocarcinoma, derived from metastatic site: pleural effusion http://www.lgcstandards-atcc.org/products/all/HTB-21.aspx?gclid=Cj0KEQjw6deeBRCswoauquC8haUBEiQAdq5zh_8UuH2LvwJZhI8PgJMkbdeRwWUGeOBeWeE8leDHvmUaAqa18P8HAQ&geo_country=gb ATCC HTB-21 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu Accepted 2014-AUG-07 by ORCHARD Cancer Cell (1535-6108) 2014 Only protein-protein interactions imex curation JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. Cancer Cell (1535-6108) 2014 imex curation Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu 18-Sep-2014: Contacted by IntAct-Help. Only protein-protein interactions human-sum159pt Human SUM-159PT Anaplastic carcinoma, triple-negative sum-159pt SUM-159PT Anaplastic carcinoma, triple-negative anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu Accepted 2014-AUG-07 by ORCHARD Cancer Cell (1535-6108) 2014 Only protein-protein interactions imex curation JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. Cancer Cell (1535-6108) 2014 imex curation Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu 18-Sep-2014: Contacted by IntAct-Help. Only protein-protein interactions human-sum159pt Human SUM-159PT Anaplastic carcinoma, triple-negative sum-159pt SUM-159PT Anaplastic carcinoma, triple-negative anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu Accepted 2014-AUG-07 by ORCHARD Cancer Cell (1535-6108) 2014 Only protein-protein interactions imex curation JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. Cancer Cell (1535-6108) 2014 imex curation Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu 18-Sep-2014: Contacted by IntAct-Help. Only protein-protein interactions human-hcc2157 Human HCC2157 primary ductal carcinoma, Pr+,ERBB2+,ER- hcc2157 Human HCC2157 primary ductal carcinoma, Pr+,ERBB2+,ER- http://www.lgcstandards-atcc.org/products/all/CRL-2340.aspx?geo_country=gb anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu Accepted 2014-AUG-07 by ORCHARD Cancer Cell (1535-6108) 2014 Only protein-protein interactions imex curation JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. Cancer Cell (1535-6108) 2014 imex curation Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu 18-Sep-2014: Contacted by IntAct-Help. Only protein-protein interactions human-mcf7 Homo sapiens mammary carcinoma cells mcf7 mammary carcinoma cells ch-ip chromatin immunoprecipitation assay ch-ip q-pcr quantitative pcr q-pcr Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu Accepted 2014-AUG-07 by ORCHARD Cancer Cell (1535-6108) 2014 Only protein-protein interactions imex curation JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. Cancer Cell (1535-6108) 2014 imex curation Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu 18-Sep-2014: Contacted by IntAct-Help. Only protein-protein interactions human-mcf7 Homo sapiens mammary carcinoma cells mcf7 mammary carcinoma cells anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu Accepted 2014-AUG-07 by ORCHARD Cancer Cell (1535-6108) 2014 Only protein-protein interactions imex curation JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. Cancer Cell (1535-6108) 2014 imex curation Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu 18-Sep-2014: Contacted by IntAct-Help. Only protein-protein interactions human-t47d human breast cancer tumour cell line-epithelial cells t47d Epithelial cells derived from human breast tumour anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu Accepted 2014-AUG-07 by ORCHARD Cancer Cell (1535-6108) 2014 Only protein-protein interactions imex curation JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. Cancer Cell (1535-6108) 2014 imex curation Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu 18-Sep-2014: Contacted by IntAct-Help. Only protein-protein interactions human-mcf7 Homo sapiens mammary carcinoma cells mcf7 mammary carcinoma cells anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu Accepted 2014-AUG-07 by ORCHARD Cancer Cell (1535-6108) 2014 Only protein-protein interactions imex curation JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer. Cancer Cell (1535-6108) 2014 imex curation Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu 18-Sep-2014: Contacted by IntAct-Help. Only protein-protein interactions human-sum52pe Human SUM52PE - pleural effusion of a metastatic breast carcinoma, triple negative sum52pe Human SUM52PE - pleural effusion of a metastatic breast carcinoma, triple negative anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Yamamoto S., Wu Z., Russnes H.G., Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan H.K., Maruyama R., Ekram M.B., Sun H., Kim J.H., Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda O.M., Nikolsky Y., Caldas C., Liu X.S., Polyak K. Cancer - Interactions investigated in the context of cancer Kornelia_Polyak@dfci.harvard.edu Accepted 2014-AUG-07 by ORCHARD Cancer Cell (1535-6108) 2014 Only protein-protein interactions imex curation cld1_human_gene Claudin-1 CLDN1 CLD1 SEMP1 Senescence-associated epithelial membrane protein gene gene human Homo sapiens Human abca4_human_gene Retinal-specific ATP-binding cassette transporter ABCA4 ABCR ATP-binding cassette sub-family A member 4 RIM ABC transporter Stargardt disease protein gene gene human Homo sapiens Human ctgf_human_gene CTGF_HUMAN_GENE gene gene human Homo sapiens Human elf3_human_gene ETS-related transcription factor Elf-3 ELF3 ERT ESX JEN E74-like factor 3 Epithelial-restricted with serine box Epithelium-restricted Ets protein ESX Epithelium-specific Ets transcription factor 1 gene gene human Homo sapiens Human cc14a_human_gene Dual specificity protein phosphatase CDC14A CDC14A CDC14 cell division cycle 14 homolog A gene gene human Homo sapiens Human call5_human_gene Calmodulin-like protein 5 CALML5 CLSP Calmodulin-like skin protein gene gene human Homo sapiens Human kdm5b_human Lysine-specific demethylase 5B KDM5B JARID1B PLU1 RBBP2H1 Histone demethylase JARID1B Jumonji/ARID domain-containing protein 1B PLU-1 Retinoblastoma-binding protein 2 homolog 1 Cancer/testis antigen 31 [histone H3]-trimethyl-L-lysine(4) demethylase 5B protein protein human Homo sapiens Human MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARDWLQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLTENSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETASAMATLGEARLREMEALQSLRLANEGKLLSPLQDVDIKICLCQKAPAAPMIQCELCRDAFHTSCVAVPSISQGLRIWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRAQQLLSSGNLKFVQDRVGSGLLYSRWQASAGQVSDTNKVSQPPGTTSFSLPDDWDNRTSYLHSPFSTGRSCIPLHGVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQTDRSSPVRPSSEKNDCCRGKRDGINSLERKLKRRLEREGLSSERWERVKKMRTPKKKKIKLSHPKDMNNFKLERERSYELVRSAETHSLPSDTSYSEQEDSEDEDAICPAVSCLQPEGDEVDWVQCDGSCNQWFHQVCVGVSPEMAEKEDYICVRCTVKDAPSRK DIP protein Q9UGL1 original sequence version: 62 70A0738D9A709F61 pald_human_gene Paladin PALD1 KIAA1274 PALD gene gene human Homo sapiens Human ctcf_human Transcriptional repressor CTCF CCCTC-binding factor CTCFL paralog 11-zinc finger protein CTCF protein protein human Homo sapiens Human MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQMVMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPVPVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVKVGANGEVETLEQGELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEVNAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCGRAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYASVEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSGTMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERYALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKRKMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGRTNQPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEMILSMMDR DIP protein P49711 original sequence version: 116 2110538B65DC5706 spdef_human_gene SAM pointed domain-containing Ets transcription factor SPDEF PDEF PSE Prostate epithelium-specific Ets transcription factor Prostate-derived Ets factor gene gene human Homo sapiens Human wnt3a_human_gene Protein Wnt-3a WNT3A gene gene human Homo sapiens Human fst_human_gene Follistatin FST Activin-binding protein gene gene human Homo sapiens Human brca1_human_gene breast cancer 1, early onset gene gene human Homo sapiens Human cav1_human_gene Caveolin-1 CAV1 CAV gene gene human Homo sapiens Human ptgis_human_gene Prostacyclin synthase PTGIS CYP8 CYP8A1 Prostaglandin I2 synthase gene gene human Homo sapiens Human actbl_human_gene Beta-actin-like protein 2 ACTBL2 Kappa-actin gene gene human Homo sapiens Human tgfb2_human_gene Transforming growth factor beta-2 TGFB2 BSC-1 cell growth inhibitor Cetermin Glioblastoma-derived T-cell suppressor factor Polyergin gene gene human Homo sapiens Human chst3_human_gene Carbohydrate sulfotransferase 3 CHST3 Chondroitin 6-O-sulfotransferase 1 Chondroitin 6-sulfotransferase Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0 gene gene human Homo sapiens Human djb12_human_gene DnaJ homolog subfamily B member 12 DNAJB12 gene gene human Homo sapiens Human esrp1_human_gene Epithelial splicing regulatory protein 1 ESRP1 RBM35A RNA-binding motif protein 35A RNA-binding protein 35A gene gene human Homo sapiens Human kdm5b-tgfb2 6 27 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 17 unspecified role unspecified role bait bait association association 3F/Gi JARID1B and H3K4me3/me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me3/me2 levels increased. kdm5b-tgfb2-1 6 22 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 17 unspecified role unspecified role bait bait association association 3F/Gii JARID1B and H3K4me3/me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me3 levels increased. kdm5b-tgfb2-2 6 17 unspecified role unspecified role bait bait 13 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 3F/Giii JARID1B and H3K4me3/me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me3/me2 levels increased. kdm5b-ctgf 6 17 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 3F/Giv JARID1B and H3K4me3/me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me3/me2 levels increased. kdm5b-ctcf 7 19 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association 6D kdm5b-ctcf-1 8 19 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association 6D kdm5b-ctcf-2 2 19 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association 6D kdm5b-ctcf-3 3 19 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association 6D kdm5b-ctcf-4 10 17 unspecified role unspecified role bait bait 19 unspecified role unspecified role prey prey physical association physical association 6D kdm5b-ctcf-5 5 19 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association 6D kdm5b-chst3 1 28 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q9UGL1:p.Lys1435Arg mutation mutation certain certain sequence position certain certain certain sequence position certain K R Wed May 02 17:06:12 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 15:48:48 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range association association 7D-1 kdm5b-chst3-1 1 12 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q9UGL1:p.Lys1435Arg mutation mutation certain certain sequence position certain certain certain sequence position certain K R Wed May 02 19:13:35 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 18:30:41 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range association association 7D-2 kdm5b-abca4 1 25 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait Q9UGL1:p.Lys1435Arg mutation mutation certain certain sequence position certain certain certain sequence position certain K R Wed May 02 18:17:14 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 17:07:38 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range association association 7D-3 kdm5b-ptgis 1 17 unspecified role unspecified role bait bait Q9UGL1:p.Lys1435Arg mutation mutation certain certain sequence position certain certain certain sequence position certain K R Wed May 02 19:37:31 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 18:47:00 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 28 unspecified role unspecified role prey prey association association 7D-4 kdm5b-chst3-2 1 17 unspecified role unspecified role bait bait n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q9UGL1:p.Lys1435Arg mutation mutation certain certain sequence position certain certain certain sequence position certain K R Wed May 02 17:11:04 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 20:09:23 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' 16 unspecified role unspecified role prey prey association association 7D-5 kdm5b-calml5-1 1 17 unspecified role unspecified role bait bait Q9UGL1:p.Lys1435Arg mutation mutation certain certain sequence position certain certain certain sequence position certain K R Wed May 02 15:27:43 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 18:43:43 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 18 unspecified role unspecified role prey prey association association 7D-6 kdm5b-pald1 1 26 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q9UGL1:p.Lys1435Arg mutation mutation certain certain sequence position certain certain certain sequence position certain K R Wed May 02 16:12:01 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 18:25:12 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range association association 7D-7 kdm5b-actbl2 1 17 unspecified role unspecified role bait bait n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q9UGL1:p.Lys1435Arg mutation mutation certain certain sequence position certain certain certain sequence position certain K R Wed May 02 15:30:10 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 18:23:22 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 14 unspecified role unspecified role prey prey association association 7D-8 kdm5b-elf3 1 17 unspecified role unspecified role bait bait n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q9UGL1:p.Lys1435Arg mutation mutation certain certain sequence position certain certain certain sequence position certain K R Wed May 02 19:47:45 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 19:43:59 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' 29 unspecified role unspecified role prey prey association association 7D-10 kdm5b-dnajb12 1 20 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait Q9UGL1:p.Lys1435Arg mutation mutation certain certain sequence position certain certain certain sequence position certain K R Wed May 02 17:48:16 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 17:21:34 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range association association 7D-11 kdm5b-spdef 1 17 unspecified role unspecified role bait bait n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q9UGL1:p.Lys1435Arg mutation mutation certain certain sequence position certain certain certain sequence position certain K R Wed May 02 20:25:13 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 17:14:48 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' 30 unspecified role unspecified role prey prey association association 7D-12 kdm5b-chst3-3 4 17 unspecified role unspecified role bait bait n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q9UGL1:p.Lys1435Arg mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength certain certain sequence position certain certain certain sequence position certain K R Wed May 02 19:33:33 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 16:22:38 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' 19 unspecified role unspecified role prey prey physical association physical association 7F kdm5b-chst3-4 9 17 unspecified role unspecified role bait bait n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range n_terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q9UGL1:p.Lys1435Arg mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength certain certain sequence position certain certain certain sequence position certain K R Wed May 02 16:08:39 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys1435arg' Tue Jun 30 18:32:38 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys1435Arg' 19 unspecified role unspecified role prey prey physical association physical association 7F kdm5b-cldn1 6 23 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 17 unspecified role unspecified role bait bait association association Supp Fig3A JARID1B and H3K4me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me2 levels increased. kdm5b-brca1 6 24 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 17 unspecified role unspecified role bait bait association association Supp Fig3 kdm5b-cav1 6 15 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 17 unspecified role unspecified role bait bait association association Supp Fig 3C JARID1B and H3K4me2 have overlapping peaks in the promoter region. After JARID1B knockdown H3K4me2 levels increased. kdm5b-cdc14a 6 17 unspecified role unspecified role bait bait 21 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Supp Fig 3Ci