Molecular Connections Molecular Connections Pvt. Ltd. 2/2, Kariappa Road, Basavanagudi, Bangalore -560 004 www.molecularconnections.com Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme. Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme. Mol. Cancer 2013 imex curation DeSouza L.V., Matta A., Karim Z., Mukherjee J., Wang X.S., Krakovska O., Zadeh G., Guha A., Siu K.M. Cancer - Interactions investigated in the context of cancer kwmsiu@yorku.ca 18-Feb-2014: Contacted by IntAct-Help. Only protein-protein interactions Molecular Connections Pvt. Ltd. human-u87 Human U-87 MG glioblastoma cell line u87 confocal microscopy confocal microscopy immunocytochemistry immunocytochemistry DeSouza L.V., Matta A., Karim Z., Mukherjee J., Wang X.S., Krakovska O., Zadeh G., Guha A., Siu K.M. Cancer - Interactions investigated in the context of cancer kwmsiu@y orku.ca kwmsiu@yorku.ca Accepted 2014-JAN-20 by MGT Mol. Cancer 2013 Only protein-protein interactions imex curation Molecular Connections Pvt. Ltd. Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme. Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme. Mol. Cancer 2013 imex curation DeSouza L.V., Matta A., Karim Z., Mukherjee J., Wang X.S., Krakovska O., Zadeh G., Guha A., Siu K.M. Cancer - Interactions investigated in the context of cancer kwmsiu@yorku.ca 18-Feb-2014: Contacted by IntAct-Help. Only protein-protein interactions Molecular Connections Pvt. Ltd. human-u373 Homo sapiens u373 u373 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot DeSouza L.V., Matta A., Karim Z., Mukherjee J., Wang X.S., Krakovska O., Zadeh G., Guha A., Siu K.M. Cancer - Interactions investigated in the context of cancer kwmsiu@y orku.ca kwmsiu@yorku.ca Accepted 2014-JAN-20 by MGT Mol. Cancer 2013 Only protein-protein interactions imex curation Molecular Connections Pvt. Ltd. Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme. Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme. Mol. Cancer 2013 imex curation DeSouza L.V., Matta A., Karim Z., Mukherjee J., Wang X.S., Krakovska O., Zadeh G., Guha A., Siu K.M. Cancer - Interactions investigated in the context of cancer kwmsiu@yorku.ca 18-Feb-2014: Contacted by IntAct-Help. Only protein-protein interactions Molecular Connections Pvt. Ltd. human-u87 Human U-87 MG glioblastoma cell line u87 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot DeSouza L.V., Matta A., Karim Z., Mukherjee J., Wang X.S., Krakovska O., Zadeh G., Guha A., Siu K.M. Cancer - Interactions investigated in the context of cancer kwmsiu@y orku.ca kwmsiu@yorku.ca Accepted 2014-JAN-20 by MGT Mol. Cancer 2013 Only protein-protein interactions imex curation Molecular Connections Pvt. Ltd. Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme. Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme. Mol. Cancer 2013 imex curation DeSouza L.V., Matta A., Karim Z., Mukherjee J., Wang X.S., Krakovska O., Zadeh G., Guha A., Siu K.M. Cancer - Interactions investigated in the context of cancer kwmsiu@yorku.ca 18-Feb-2014: Contacted by IntAct-Help. Only protein-protein interactions Molecular Connections Pvt. Ltd. human-u373 Homo sapiens u373 u373 confocal microscopy confocal microscopy immunocytochemistry immunocytochemistry DeSouza L.V., Matta A., Karim Z., Mukherjee J., Wang X.S., Krakovska O., Zadeh G., Guha A., Siu K.M. Cancer - Interactions investigated in the context of cancer kwmsiu@y orku.ca kwmsiu@yorku.ca Accepted 2014-JAN-20 by MGT Mol. Cancer 2013 Only protein-protein interactions imex curation Molecular Connections Pvt. Ltd. moes_human Moesin Membrane-organizing extension spike protein MSN protein protein human Homo sapiens Human MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM DIP protein P26038 original sequence version: 168 865A6C5CB14AE586 cd44_human CD44 antigen Epican CDw44 Phagocytic glycoprotein I Extracellular matrix receptor III HUTCH-I Phagocytic glycoprotein 1 GP90 lymphocyte homing/adhesion receptor Hermes antigen Hyaluronate receptor Heparan sulfate proteoglycan CD44 LHR MDU2 MDU3 MIC4 protein protein human Homo sapiens Human MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV DIP protein P16070 original sequence version: 142 DIP protein P16070 original sequence version: 157 BB9B66B19B970349 cd44-msn 3 6 unspecified role unspecified role bait bait 5 unspecified role unspecified role prey prey physical association physical association 4b Interaction happens only in presence of Hyaluronan or TNF. msn-cd44 3 5 unspecified role unspecified role bait bait 6 unspecified role unspecified role prey prey physical association physical association Interaction happens only in presence of Hyaluronan or TNF. 4b cd44-msn-1 2 6 unspecified role unspecified role bait bait 5 unspecified role unspecified role prey prey physical association physical association 4b Hyaluronan; TNF msn-cd44-1 2 6 unspecified role unspecified role prey prey 5 unspecified role unspecified role bait bait physical association physical association 4b Hyaluronan; TNF cd44-msn-2 4 5 unspecified role unspecified role neutral component neutral component 6 unspecified role unspecified role neutral component neutral component colocalization colocalization co-localization seen in presence of hyaluronan. 4a cd44-msn-3 1 6 unspecified role unspecified role neutral component neutral component 5 unspecified role unspecified role neutral component neutral component colocalization colocalization co-localization seen in presence of hyaluronan. 4a