IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Molecular basis of proton motive force generation: structure of formate dehydrogenase-N. Molecular basis of proton motive force generation: structure of formate dehydrogenase-N. Science (0036-8075) 2002 imex curation Jormakka M., Törnroth S., Byrne B., Iwata S. s.iwata@ic.ac.uk 02-Aug-2013: Contacted by IntAct-Help. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Jormakka M., Törnroth S., Byrne B., Iwata S. s.iwata@ic.ac.uk Accepted 2013-JUL-22 by ORCHARD 02-Aug-2013: Contacted by IntAct-Help. Science (0036-8075) 2002 Only protein-protein interactions imex curation cardiolipin 1',3'-bis(1,2-diacyl-sn-glycero-3-phospho)-sn-glycerol small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) fdng_ecoli Formate dehydrogenase, nitrate-inducible, major subunit b1474 fdnG JW1470 Formate dehydrogenase-N subunit alpha Anaerobic formate dehydrogenase major subunit protein protein ecoli Escherichia coli (strain K12) MDVSRRQFFKICAGGMAGTTVAALGFAPKQALAQARNYKLLRAKEIRNTCTYCSVGCGLLMYSLGDGAKNAREAIYHIEGDPDHPVSRGALCPKGAGLLDYVNSENRLRYPEYRAPGSDKWQRISWEEAFSRIAKLMKADRDANFIEKNEQGVTVNRWLSTGMLCASGASNETGMLTQKFARSLGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWVDIKNANVVMVMGGNAAEAHPVGFRWAMEAKNNNDATLIVVDPRFTRTASVADIYAPIRSGTDITFLSGVLRYLIENNKINAEYVKHYTNASLLVRDDFAFEDGLFSGYDAEKRQYDKSSWNYQLDENGYAKRDETLTHPRCVWNLLKEHVSRYTPDVVENICGTPKADFLKVCEVLASTSAPDRTTTFLYALGWTQHTVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSNIQGLTDLGLLSTSLPGYLTLPSEKQVDLQSYLEANTPKATLADQVNYWSNYPKFFVSLMKSFYGDAAQKENNWGYDWLPKWDQTYDVIKYFNMMDEGKVTGYFCQGFNPVASFPDKNKVVSCLSKLKYMVVIDPLVTETSTFWQNHGESNDVDPASIQTEVFRLPSTCFAEEDGSIANSGRWLQWHWKGQDAPGEARNDGEILAGIYHHLRELYQSEGGKGVEPLMKMSWNYKQPHEPQSDEVAKENNGYALEDLYDANGVLIAKKGQLLSSFAHLRDDGTTASSCWIYTGSWTEQGNQMANRDNSDPSGLGNTLGWAWAWPLNRRVLYNRASADINGKPWDPKRMLIQWNGSKWTGNDIPDFGNAAPGTPTGPFIMQPEGMGRLFAINKMAEGPFPEHYEPIETPLGTNPLHPNVVSNPVVRLYEQDALRMGKKEQFPYVGTTYRLTEHFHTWTKHALLNAIAQPEQFVEISETLAAAKGINNGDRVTVSSKRGFIRAVAVVTRRLKPLNVNGQQVETVGIPIHWGFEGVARKGYIANTLTPNVGDANSQTPEYKAFLVNIEKA DIP protein P24183 original sequence version: 103 DIP protein P24183 original sequence version: null E4B9449D6B2407DA hqno 2-heptyl-4-hydroxyquinoline N-oxide small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) molybdopterin guanin molybdopterin guanine dinucleotide 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE dtpp-mGDP GUANOSINE-5'-DIPHOSPHATE PTERIN MOIETY OF MOLYBDOPTERIN GUANOSINE DINUCLEOTIDE H2Dtpp-mGDP MOLYBDOPTERIN GUANOSINE DINUCLEOTIDE 5'-O-[{[({[(5aR,8R,9aR)-2-amino-4-oxo-6,7-disulfanyl-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl}oxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]guanosine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) VQAGYJCYOLHZDH-ILXWUORBSA-N VQAGYJCYOLHZDH-ILXWUORBSA-N fe4-s4 tetra-μ3-sulfido-tetrairon small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) fdni_ecoli Formate dehydrogenase, nitrate-inducible, cytochrome b556(Fdn) subunit fdnI b1476 JW1472 Formate dehydrogenase-N subunit gamma Anaerobic formate dehydrogenase cytochrome b556 subunit protein protein ecoli Escherichia coli (strain K12) MSKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLTQTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNIPDKKDIPWLLNIVEVLKGNEHKVADVGKYNAGQKMMFWSIMSMIFVLLVTGVIIWRPYFAQYFPMQVVRYSLLIHAAAGIILIHAILIHMYMAFWVKGSIKGMIEGKVSRRWAKKHHPRWYREIEKAEAKKESEEGI B10073F14343515E molybdenum atom molybdenum atom 42Mo Mo molibdeno Molybdaen molybdene Molybdenum molybdenum molybdenum small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) ZOKXTWBITQBERF-UHFFFAOYSA-N ZOKXTWBITQBERF-UHFFFAOYSA-N fdnh_ecoli Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit b1475 fdnH Formate dehydrogenase-N subunit beta Anaerobic formate dehydrogenase iron-sulfur subunit JW1471 protein protein ecoli Escherichia coli (strain K12) MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKACQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCMHCEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKCTLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEGVGGTHVMYVLHHADQPELYHGLPKDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHYIGIGPNKEVDDDEEDHHE 44F361F4AC0AEF36 heme heme small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) fdh_n-hqno 1 3 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) 9 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) 7 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) 6 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) 8 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) 5 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) 4 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) 10 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) 2 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) physical association physical association Fig.s 2-5, Table 1 R = 0.2; Rwork = 0.2; Rfree = 0.24 2.8 A fdng-fdnh-1 1 10 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) 9 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) 7 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) 3 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) 6 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) 8 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) 5 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) 2 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) physical association physical association Fig.s 2-5, Table 1 R = 0.18; Rwork = 0.18; Rfree = 0.2 1.6 A