IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Cell (0092-8674) 2012 imex curation Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp 19-Sept-2012: Contacted by IntAct-Help. Only protein-protein interactions rat-neuron Rattus norvegicus neuronal cell neuron Neuron [Neuronal cell; Neural cell anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Brain synaptosomal fractions. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp Accepted 2012-AUG-09 by PPORRAS 19-Sept-2012: Contacted by IntAct-Help. Cell (0092-8674) 2012 Only protein-protein interactions imex curation Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Cell (0092-8674) 2012 imex curation Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp 19-Sept-2012: Contacted by IntAct-Help. Only protein-protein interactions rat-neuron Rattus norvegicus neuronal cell neuron Neuron [Neuronal cell; Neural cell fret fluorescent resonance energy transfer FRET RET FRET analysis FRET RET FRET analysis fret tag fluorescence tag visualisation by fluorescence tag fluorescence Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp Accepted 2012-AUG-09 by PPORRAS 19-Sept-2012: Contacted by IntAct-Help. Cell (0092-8674) 2012 Only protein-protein interactions imex curation Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Cell (0092-8674) 2012 imex curation Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp 19-Sept-2012: Contacted by IntAct-Help. Only protein-protein interactions mouse-brain Mus musculus brain brain Brain [cerebrum] anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp Accepted 2012-AUG-09 by PPORRAS 19-Sept-2012: Contacted by IntAct-Help. Cell (0092-8674) 2012 Only protein-protein interactions imex curation Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Cell (0092-8674) 2012 imex curation Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp 19-Sept-2012: Contacted by IntAct-Help. Only protein-protein interactions rat-neuron Rattus norvegicus neuronal cell neuron Neuron [Neuronal cell; Neural cell confocal microscopy confocal microscopy immunostaining immunostaining Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp Accepted 2012-AUG-09 by PPORRAS 19-Sept-2012: Contacted by IntAct-Help. Cell (0092-8674) 2012 Only protein-protein interactions imex curation Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Cell (0092-8674) 2012 imex curation Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp 19-Sept-2012: Contacted by IntAct-Help. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Although this assay was described in a previous paper (PMID:17088211), this specific interaction was not included in the data then published. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp Accepted 2012-AUG-09 by PPORRAS 19-Sept-2012: Contacted by IntAct-Help. A random-primed cDNA library prepared from rat seizure-stimulated cerebrum Cell (0092-8674) 2012 Only protein-protein interactions imex curation Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Cell (0092-8674) 2012 imex curation Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp 19-Sept-2012: Contacted by IntAct-Help. Only protein-protein interactions in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp Accepted 2012-AUG-09 by PPORRAS 19-Sept-2012: Contacted by IntAct-Help. Cell (0092-8674) 2012 Only protein-protein interactions imex curation Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Cell (0092-8674) 2012 imex curation Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp 19-Sept-2012: Contacted by IntAct-Help. Only protein-protein interactions human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp Accepted 2012-AUG-09 by PPORRAS 19-Sept-2012: Contacted by IntAct-Help. Cell (0092-8674) 2012 Only protein-protein interactions imex curation Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Cell (0092-8674) 2012 imex curation Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp 19-Sept-2012: Contacted by IntAct-Help. Only protein-protein interactions mouse-brain Mus musculus brain brain Brain [cerebrum] anti bait coip anti bait coimmunoprecipitation anti bait coip anti tag western anti tag western blot anti tag western Okuno H., Akashi K., Ishii Y., Yagishita-Kyo N., Suzuki K., Nonaka M., Kawashima T., Fujii H., Takemoto-Kimura S., Abe M., Natsume R., Chowdhury S., Sakimura K., Worley P.F., Bito H. Colocalisation of Arc with GluA1 and PSD-95 have not been captured as these appear only be be markers of subcellular locations. Origin of Arc confirmed by the author okuno@m.u-tokyo.ac.jp, hbito@m.u-tokyo.ac.jp Accepted 2012-AUG-09 by PPORRAS 19-Sept-2012: Contacted by IntAct-Help. Cell (0092-8674) 2012 Only protein-protein interactions imex curation arc_rat Activity-regulated cytoskeleton-associated protein Arc Activity-regulated gene 3.1 protein protein protein rat Rattus norvegicus (Rat) Rat MELDHMTTGGLHAYPAPRGGPAAKPNVILQIGKCRAEMLEHVRRTHRHLLTEVSKQVERELKGLHRSVGKLENNLDGYVPTGDSQRWKKSIKACLCRCQETIANLERWVKREMHVWREVFYRLERWADRLESMGGKYPVGSEPARHTVSVGVGGPEPYCQEADGYDYTVSPYAITPPPAAGELPEQESVGAQQYQSWVPGEDGQPSPGVDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEGTLSREAIQRELDLPQKQGEPLDQFLWRKRDLYQTLYVDAEEEEIIQYVVGTLQPKFKRFLRHPLPKTLEQLIQRGMEVQDGLEQAAEPSVTPLPTEDETEALTPALTSESVASDRTQPE 4E95B46B75853CA5 kcc2b_rat Calcium/calmodulin-dependent protein kinase type II subunit beta Camk2b protein protein rat Rattus norvegicus (Rat) Rat MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSSAITSPKGSLPPAALEPQTTVIHNPVDGIKESSDSTNTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRPDGKWQNVHFHCSGAPVAPLQ DIP protein P08413 original sequence version: 128 8A7962A64AE930D0 kcc2b_mouse Calcium/calmodulin-dependent protein kinase type II subunit beta Camk2b Camk2d protein protein mouse Mus musculus Mouse MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSSAITSPKGSLPPAALEPQTTVIHNPVDGIKESSDSTNTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ DIP protein P28652 original sequence version: 88 8A7962A6495FD0D0 arc_mouse Activity-regulated cytoskeleton-associated protein Arc Activity-regulated gene 3.1 protein protein protein mouse Mus musculus Mouse MELDHMTTGGLHAYPAPRGGPAAKPNVILQIGKCRAEMLEHVRRTHRHLLTEVSKQVERELKGLHRSVGKLENNLDGYVPTGDSQRWKKSIKACLCRCQETIANLERWVKREMHVWREVFYRLERWADRLESMGGKYPVGSEPARHTVSVGVGGPEPYCQEADGYDYTVSPYAITPPPAAGELPEQESVEAQQYQSWGPGEDGQPSPGVDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEGTLSREAIQRELELPQKQGEPLDQFLWRKRDLYQTLYVDAEEEEIIQYVVGTLQPKLKRFLRHPLPKTLEQLIQRGMEVQDGLEQAAEPSGTPLPTEDETEALTPALTSESVASDRTQPE DIP protein Q9WV31 original sequence version: 78 F4D3505FD477D18A kcc2a_rat Calcium/calmodulin-dependent protein kinase type II subunit alpha Camk2a protein protein rat Rattus norvegicus (Rat) Rat MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH DIP protein P11275 original sequence version: 135 DIP protein P11275 original sequence version: 82 DIP protein P11275 original sequence version: 134 DIP protein P11275 original sequence version: 117 306F416CCE9B5F62 arc-camk2b 5 10 unspecified role unspecified role prey prey 9 unspecified role unspecified role bait bait physical association physical association arc-camk2b-1 7 9 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection 10 unspecified role unspecified role prey prey nucl transfection nucleic acid transfection nucl transfection physical association physical association Supp. Fig. 1A arc-camk2b-2 4 10 unspecified role unspecified role neutral component neutral component 9 unspecified role unspecified role neutral component neutral component colocalization colocalization Fig. 1A camk2b-arc 3 11 unspecified role unspecified role bait bait 12 unspecified role unspecified role prey prey physical association physical association Fig. 1B, Supp. Fig. 7B arc-camk2b-3 6 10 unspecified role unspecified role prey prey nucl transfection nucleic acid transfection nucl transfection P08413:p.Thr287Asp mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain T D Wed May 02 17:59:10 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr287asp' Tue Jun 30 18:07:46 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Thr287Asp' human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. 9 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) direct interaction direct interaction Fig. 1C, 1D, 6B, C, D, Supp. Fig. 1F This interaction was strong in the absence of Ca2+ and calmodulin (CaM) but was attenuated when Ca2+/CaM was present. Inhibition of CaM activation by W-7 (100 uM) in the presence of Ca2+/CaM restored Arc binding to CaMKIIB. arc-camk2a 6 13 unspecified role unspecified role prey prey human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. 9 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) direct interaction direct interaction Fig. 1D, Supp. Figs. 1E, 1F interaction was observed only in the presence of Ca2+/CaM. arc-camk2b-5 2 9 unspecified role unspecified role fluorescence accept fluorescence acceptor fluorescence accept region cfp tag cyan fluorescent protein tag CFP cyan fluorescent protein cyan fluorescent protein CFP cfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 unspecified role unspecified role fluorescence donor fluorescence donor region yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined proximity proximity close-contact colocalization neighbourhood interaction Supp. Fig. 1C camk2b-arc-4 8 11 unspecified role unspecified role bait bait 12 unspecified role unspecified role prey prey region egfp tag enhanced green fluorescent protein tag enhanced green fluorescent protein EGFP enhanced green fluorescent protein EGFP egfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Supp. Fig. 7B camk2b-arc-3 1 10 unspecified role unspecified role bait bait 9 unspecified role unspecified role prey prey physical association physical association Fig. 1B