UniProt UniProt http://www.uniprot.org The three-dimensional structural basis of type II hyperprolinemia. The three-dimensional structural basis of type II hyperprolinemia. J. Mol. Biol. (0022-2836) 2012 mimix curation Srivastava D., Singh R.K., Moxley M.A., Henzl M.T., Becker D.F., Tanner J.J. Sorry about the mouse structure. This has now been rectified. For the ITc data, etc, this is MIMIX, and I don't think we capture this sort of thing. I've been told that for MIMIX we do not add interactions with substrates or cofactors, etc. 11-Oct-2012: Contacted by IntAct-Help. in vitro In vitro cosedimentation cosedimentation predetermined predetermined participant predetermined Srivastava D., Singh R.K., Moxley M.A., Henzl M.T., Becker D.F., Tanner J.J. Sorry about the mouse structure. This has now been rectified. For the ITc data, etc, this is MIMIX, and I don't think we capture this sort of thing. I've been told that for MIMIX we do not add interactions with substrates or cofactors, etc. Accepted 2012-SEP-25 by MGT 11-Oct-2012: Contacted by IntAct-Help. J. Mol. Biol. (0022-2836) 2012 mimix curation The three-dimensional structural basis of type II hyperprolinemia. The three-dimensional structural basis of type II hyperprolinemia. J. Mol. Biol. (0022-2836) 2012 mimix curation Srivastava D., Singh R.K., Moxley M.A., Henzl M.T., Becker D.F., Tanner J.J. Sorry about the mouse structure. This has now been rectified. For the ITc data, etc, this is MIMIX, and I don't think we capture this sort of thing. I've been told that for MIMIX we do not add interactions with substrates or cofactors, etc. 11-Oct-2012: Contacted by IntAct-Help. in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Srivastava D., Singh R.K., Moxley M.A., Henzl M.T., Becker D.F., Tanner J.J. Sorry about the mouse structure. This has now been rectified. For the ITc data, etc, this is MIMIX, and I don't think we capture this sort of thing. I've been told that for MIMIX we do not add interactions with substrates or cofactors, etc. Accepted 2012-SEP-25 by MGT 11-Oct-2012: Contacted by IntAct-Help. J. Mol. Biol. (0022-2836) 2012 mimix curation al4a1_mouse Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial Aldh4a1 Aldehyde dehydrogenase family 4 member A1 L-glutamate gamma-semialdehyde dehydrogenase protein protein mouse Mus musculus Mouse MLPLPSLRRSLLSHAWRGAGLRWKHTSSLKVTNEPILAFSQGSPERDALQKALKDLKGQMEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLQLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYMQ 4D8A0C9C68A99478 al4a1_human Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 ALDH4 P5CDH Aldehyde dehydrogenase family 4 member A1 L-glutamate gamma-semialdehyde dehydrogenase protein protein human Homo sapiens Human MLLPAPALRRALLSRPWTGAGLRWKHTSSLKVANEPVLAFTQGSPERDALQKALKDLKGRMEAIPCVVGDEEVWTSDVQYQVSPFNHGHKVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWSYAYMQ 4D964771B7DB5FFD aldh4a1-1 2 4 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) direct interaction direct interaction R-factor: 20.48%, Free R-factor: 23.85% for 3v9g R-factor: 21.07%, Free R-factor: 25.08% for 3v9h R-factor: 21.06%, Free R-factor: 26.4% for 3v9i 2.5 A for 3V9G, 2.4 A 3V9H, 2.85 A for 3V9I aldh4a1-1 1 4 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) direct interaction direct interaction Fig 3. aldh4a1-1 2 3 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) direct interaction direct interaction 1.30 A for 3V9J; 1.50 A for 3V9K 1.50 A for 3V9L R-Value: 0.133 (obs.) for 3V9J, R-Free: 0.160 for 3V9J, R-Value: 0.159 (obs.) for 3V9L, R-Free: 0.176 for 3V9L, R-Value: 0.152 (obs.) for 3V9K, R-Free: 0.169 for 3V9K