MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it RWD domain: a recurring module in kinetochore architecture shown by a Ctf19-Mcm21 complex structure. RWD domain: a recurring module in kinetochore architecture shown by a Ctf19-Mcm21 complex structure. EMBO Rep. (1469-221X) 2012 imex curation Schmitzberger F., Harrison SC. Only protein-protein interactions in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column weight by comassie molecular weight estimation by coomasie staining weight by comassie Schmitzberger F., Harrison SC. EMBO Rep. (1469-221X) 2012 Only protein-protein interactions imex curation RWD domain: a recurring module in kinetochore architecture shown by a Ctf19-Mcm21 complex structure. RWD domain: a recurring module in kinetochore architecture shown by a Ctf19-Mcm21 complex structure. EMBO Rep. (1469-221X) 2012 imex curation Schmitzberger F., Harrison SC. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Schmitzberger F., Harrison SC. EMBO Rep. (1469-221X) 2012 Only protein-protein interactions imex curation cenpo_klula Inner kinetochore subunit MCM21 MCM21 Minichromosome maintenance protein 21 KLLA0B10142g CENP-O homolog Constitutive centromere-associated network protein MCM21 protein protein klula Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) Yeast Candida sphaerica MEETEAVQQDIEALEREIQTIKIQIANAHSGASKDEVKIPDAYKQFLSENINFSNLMRKDENTTLSINLSPRKPGTTTGQIQGIDSSIRSNFGVSSGHNEVAGFKSITDFVQWENSVRLIGVSLFPVNYDNIEFMGIRLELFDELSLKYDPPFYVILKPSVKRLGIWELFKHNLPKYINIHQHWQLITKDTDTSDSNIMKFANLCYKDLLKVHSRVQFFRKLEGNYVNDKQYSLLHIDNMGLNVSFRLGADIIKIKVDDGDDEIIDCTFNGEKNISLLGSIYGITNRFQSIIM mint 7932BDB56BCC3691 cenpq_klula Inner kinetochore subunit OKP1 KLLA0F15136g OKP1 CENP-Q homolog Constitutive centromere-associated network protein OKP1 protein protein klula Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) Yeast Candida sphaerica MSKRYLDDVLSPDTGTSDSDSSIENLNADNYRIDIVNDNARRDDIDRIQSSNLNHEPPYNLEGVFAIDDDEHGDEMVRKDSDRRQDITEDNDDSFVPDITTPPRERKRVRFGINEKGGDEEFNNVSPWDFKRLIRKFYKEQLPDTYQIRNWKRPSKDMLTNFIDLIENNIELASEEVFKQYHQELNQLYPDSEEQAKLKDSLENKVFDTTYNIKKRLKRTKVPSKIWVDNLNMEYIYAKGESIKKRYKSELDRAEAIERQLIREEEHLKSLQEKGETQAKKRKQVLSKELSELSKTMHPSLSVALSNTFGLIKDDKMSNEIYQQDKIDFNLKLKTDFSKPLISEKEENSLNGLTNAMDNNRELVNEIFGKISALLQPKKNSNE mint 48BD096F97D21E48 cenpp_klula Inner kinetochore subunit CTF19 CTF19 CENP-P homolog Constitutive centromere-associated network protein CTF19 KLLA0D07612g protein protein klula Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) Yeast Candida sphaerica MDFTSSSGVLDSERNTGSNDSDEPSSHSDVIETEELKLIKLQEHKNNLLRQRSELLDQLSQTRVVEPRSVQLDDKLLLKLLRRNDNAVSDSSQSSNNPLPRVLPSLNIEQRKKYLDITLNDVTVTCEKDMILLRKGSFTASFRIAVENESIRSMAIDLNAFEVELQPIIQYAEDTQNVNVAMMAVVQFLRIKELHEQMISKIVEASKFIRASNNTITLNDLEVSFHCYWNLPSPYPETLILTNKVQKILDFLIYQYGIQLGVIKYGSTII mint 2B86807BAE9F2850 cenpu_klula Inner kinetochore subunit AME1 KLLA0C05500g AME1 CENP-U homolog Constitutive centromere-associated network protein AME1 protein protein klula Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) Yeast Candida sphaerica MDALKQRHLKLLYRQRGSASRTIDYDVVIEPELREDGDLVTDSQLTEQDDQSFPDIQVPSPDRVDDFDLNQGDGLMDKATANEDDIDHVIGDEVAAVNAPVETSDLVIDTTQFDSMTLSQLSTPLTSMATIDVLRRLLETVILVTIEERTSQFNRAGSARLRLKLKLEIKILTWFLHQSKEDLITISELNLSNNDLLYRLKQISLLKNSLSRSLLDVRSAISSYEGPNNALSEEQVALQNFKRINELILSQRIDTIINNNLPPDTSTFDTESKKGLLPTLKTLNESLQNTIG mint 69C5495FFA97D392 ctf19-mcm21 2 CTF19 5 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified MCM21 3 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified direct interaction direct interaction mint PDB accession number: 3ZXU st1 f2 f4 sf1 sf2 sf4 sf7 ctf19-mcm21-1 1 MCM21 3 weight by comassie molecular weight estimation by coomasie staining weight by comassie predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified CTF19 5 weight by comassie molecular weight estimation by coomasie staining weight by comassie predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified direct interaction direct interaction f1a mint ctf19-mcm21-2 1 CTF19 5 weight by comassie molecular weight estimation by coomasie staining weight by comassie predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Ame1 6 weight by comassie molecular weight estimation by coomasie staining weight by comassie predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified Okp1 4 weight by comassie molecular weight estimation by coomasie staining weight by comassie predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified MCM21 3 weight by comassie molecular weight estimation by coomasie staining weight by comassie predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified his tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain physical association physical association f1b f1c mint