IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. Cancer Cell (1535-6108) 2012 imex curation Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Only protein-protein interactions human-colon_cancer human colonic cancer tissue Human colon_cancer Colon cancer tisuue ch-ip chromatin immunoprecipitation assay ch-ip primer specific pcr primer specific pcr Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Accepted 2012-FEB-10 by ORCHARD Cancer Cell (1535-6108) 2012 Only protein-protein interactions imex curation CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. Cancer Cell (1535-6108) 2012 imex curation Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Only protein-protein interactions human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Accepted 2012-FEB-10 by ORCHARD Cancer Cell (1535-6108) 2012 Only protein-protein interactions imex curation CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. Cancer Cell (1535-6108) 2012 imex curation Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Only protein-protein interactions human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Accepted 2012-FEB-10 by ORCHARD Cancer Cell (1535-6108) 2012 Only protein-protein interactions imex curation CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. Cancer Cell (1535-6108) 2012 imex curation Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Only protein-protein interactions in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Accepted 2012-FEB-10 by ORCHARD Cancer Cell (1535-6108) 2012 Only protein-protein interactions imex curation CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. Cancer Cell (1535-6108) 2012 imex curation Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Only protein-protein interactions human-colon_cancer human colonic cancer tissue Human colon_cancer Colon cancer tisuue ch-ip chromatin immunoprecipitation assay ch-ip primer specific pcr primer specific pcr Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. ChIP-3C (Chromosome Conformation Capture Assay) zhijiec@tsinghua.edu.cn, baoqingjia@126.com Accepted 2012-FEB-10 by ORCHARD Cancer Cell (1535-6108) 2012 Only protein-protein interactions imex curation CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. Cancer Cell (1535-6108) 2012 imex curation Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Only protein-protein interactions human-mgc-803 Homo sapiens mgc-803 Human-poorly differentiated human gastric adenocarcinoma MGC803 Original paper: - no pmid available. K.H. Wang The establishment and biological characteristics of a poorly differentiated human gastric adenocarcinoma MGC803 cell line. Acta Biol. Exp. Sin., 16 (1983), pp. 257–267 ch-ip chromatin immunoprecipitation assay ch-ip primer specific pcr primer specific pcr Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Accepted 2012-FEB-10 by ORCHARD Cancer Cell (1535-6108) 2012 Only protein-protein interactions imex curation CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. Cancer Cell (1535-6108) 2012 imex curation Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Only protein-protein interactions human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. anti tag coip anti tag coimmunoprecipitation anti tag coip ms participant Identification by mass spectrometry ms participant Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Accepted 2012-FEB-10 by ORCHARD Cancer Cell (1535-6108) 2012 Only protein-protein interactions imex curation CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. Cancer Cell (1535-6108) 2012 imex curation Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Only protein-protein interactions human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. crosslink cross-linking study crosslink western blot western blot Immuno blot Immuno blot Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. After formaldehyde fixation an IP was carried out. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Accepted 2012-FEB-10 by ORCHARD Cancer Cell (1535-6108) 2012 Only protein-protein interactions imex curation CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes. Cancer Cell (1535-6108) 2012 imex curation Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. zhijiec@tsinghua.edu.cn, baoqingjia@126.com Only protein-protein interactions human-mgc-803 Homo sapiens mgc-803 Human-poorly differentiated human gastric adenocarcinoma MGC803 Original paper: - no pmid available. K.H. Wang The establishment and biological characteristics of a poorly differentiated human gastric adenocarcinoma MGC803 cell line. Acta Biol. Exp. Sin., 16 (1983), pp. 257–267 ch-ip chromatin immunoprecipitation assay ch-ip primer specific pcr primer specific pcr Lu D., Wu Y., Wang Y., Ren F., Wang D., Su F., Zhang Y., Yang X., Jin G., Hao X., He D., Zhai Y., Irwin D.M., Hu J., Sung J.J., Yu J., Jia B., Chang Z. Cancer - Interactions investigated in the context of cancer The authors confirm 293T was the cell line used. Run-on/off assays(Fig 4) not included as the mRNA binding to cDNA (probably) cannot only be due to CREPT mRNA, as "nuclei" used. ChIP-3C (Chromosome Conformation Capture Assay) zhijiec@tsinghua.edu.cn, baoqingjia@126.com Accepted 2012-FEB-10 by ORCHARD Cancer Cell (1535-6108) 2012 Only protein-protein interactions imex curation rpr1b_human Regulation of nuclear pre-mRNA domain-containing protein 1B RPRD1B C20orf77 CREPT Cell cycle-related and expression-elevated protein in tumor protein protein human Homo sapiens Human MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAGDLFSTD DIP protein Q9NQG5 original sequence version: 101 9057EEF6F3D18215 ccnd1_human_gene Human Cyclin D1 gene gene gene human Homo sapiens Human rpb1_human DNA-directed RNA polymerase II subunit RPB1 POLR2A DNA-directed RNA polymerase II subunit A DNA-directed RNA polymerase III largest subunit POLR2 RNA-directed RNA polymerase II subunit RPB1 protein protein human Homo sapiens Human MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPASPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN DIP protein P24928 original sequence version: 108 DIP protein P24928 original sequence version: 147 DIP protein P24928 original sequence version: 158 DIP protein P24928 original sequence version: 157 DIP protein P24928 original sequence version: 179 DIP protein P24928 original sequence version: 181 DIP protein P24928 original sequence version: 161 DIP protein P24928 original sequence version: 175 DIP protein P24928-1 original sequence version: 175 DIP protein P24928 original sequence version: 68 DIP protein P24928 original sequence version: 116 28D6FD25693A6472 rprd1b-polr2a 7 12 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig 5A rprd1b-polr2a-1 3 12 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined rpr_domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Fig 5B myc-CREPT rather than flag-CREPT is stated to have been used in the figure legend. rprd1b-polr2a-2 2 12 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait physical association physical association Fig 5C polr2a-rprd1b 8 10 unspecified role unspecified role prey prey 12 unspecified role unspecified role bait bait physical association physical association Fig 5D rprd1b-polr2a-3 4 10 unspecified role unspecified role bait bait region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) 12 unspecified role unspecified role prey prey human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. physical association physical association Fig 5E rprd1b-ccnd1 6 11 unspecified role unspecified role prey prey pre-poly(a) cleavage site binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined promoter_p2 binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 unspecified role unspecified role bait bait association association 6B/C CREPT crosslinks strongly to a CYCLIN D1 promoter region (P2) , and also to a region related to transcription termination at the 3′ end of the gene. polr2a-ccnd1 6 11 unspecified role unspecified role prey prey promoter binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 12 unspecified role unspecified role bait bait association association 6D/E CREPT expression reduced RNAPII binding to region G - after the poly(A) site. CREPT rprd1b-ccnd1-2 9 11 unspecified role unspecified role prey prey b1_promoter_and_f1_pre-poly(a)- cleavage site_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 unspecified role unspecified role bait bait association association 6I The anti-RNAPII antibody precipitated down a strong cycled band (chromatin loop) when CREPT was overexpressed. CREPT rprd1b-ccnd1-3 1 10 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey promoter_p2 binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined pre-poly(a) cleavage site binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 7C CREPT crosslinks strongly to a CYCLIN D1 promoter region (P2) , and also to a region related to transcription termination at the 3′ end of the gene. polr2a-ccnd1-3 1 12 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey promoter_p2 binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined pre-poly(a) cleavage site binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 7D CREPT expression reduced RNAPII binding to region G - after the poly(A) site. CREPT rprd1b-ccnd1-4 5 11 unspecified role unspecified role prey prey b1_promoter_and_f1_pre-poly(a)- cleavage site_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 unspecified role unspecified role bait bait association association 6I The anti-RNAPII antibody precipitated down a strong cycled band (chromatin loop) when CREPT was overexpressed. CREPT