UniProt UniProt http://www.uniprot.org SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing. SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing. Genes Dev. (0890-9369) 2011 mimix curation Chen Y., Zhang L., Jones K.A. Origin of GST-tagged U2AF35 and U2AF65 constructs (fig 4A) according gene names used in literature (eg pmids 15096518 and 11551507, and NCBI/genes) jones@salk.edu 18-Dec-2012: Contacted by IntAct-Help. in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Chen Y., Zhang L., Jones K.A. Origin of GST-tagged U2AF35 and U2AF65 constructs (fig 4A) according gene names used in literature (eg pmids 15096518 and 11551507, and NCBI/genes) jones@salk.edu Accepted 2012-NOV-23 by ORCHARD 18-Dec-2012: Contacted by IntAct-Help. Genes Dev. (0890-9369) 2011 mimix curation SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing. SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing. Genes Dev. (0890-9369) 2011 mimix curation Chen Y., Zhang L., Jones K.A. Origin of GST-tagged U2AF35 and U2AF65 constructs (fig 4A) according gene names used in literature (eg pmids 15096518 and 11551507, and NCBI/genes) jones@salk.edu 18-Dec-2012: Contacted by IntAct-Help. human-u2-os Human U2-OS osteosarcoma cell line u2-os U2-OS osteocaroma cell line Not in CAPRI and no primary literature reference anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Chen Y., Zhang L., Jones K.A. Origin of GST-tagged U2AF35 and U2AF65 constructs (fig 4A) according gene names used in literature (eg pmids 15096518 and 11551507, and NCBI/genes) jones@salk.edu Accepted 2012-NOV-23 by ORCHARD 18-Dec-2012: Contacted by IntAct-Help. Genes Dev. (0890-9369) 2011 mimix curation snw1_human SNW domain-containing protein 1 Nuclear protein SkiP Ski-interacting protein Nuclear receptor coactivator NCoA-62 SKIIP SKIP SNW1 protein protein human Homo sapiens Human MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGDGGAFPEIHVAQYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLVPKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE DIP protein Q13573 original sequence version: 156 0CC75E0D0B2CF842 u2af2_human Splicing factor U2AF 65 kDa subunit U2AF2 U2AF65 U2 snRNP auxiliary factor large subunit U2 auxiliary factor 65 kDa subunit protein protein human Homo sapiens Human MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW DIP protein P26368 original sequence version: 86 DIP protein P26368 original sequence version: 151 DIP protein P26368-1 original sequence version: 151 DIP protein P26368 original sequence version: 124 26AD271CD8FC6211 u2af1_human Splicing factor U2AF 35 kDa subunit U2 auxiliary factor 35 kDa subunit U2 snRNP auxiliary factor small subunit U2AF1 U2AF35 U2AFBP U2 small nuclear RNA auxiliary factor 1 FP793 protein protein human Homo sapiens Human MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF 3DA130DCE0B953F6 snw1-u2af1-1 1 3 unspecified role unspecified role bait bait 4 unspecified role unspecified role prey prey 5 unspecified role unspecified role prey prey association association 4A u2af2-snw1-1 1 5 unspecified role unspecified role prey prey 3 unspecified role unspecified role prey prey 4 unspecified role unspecified role bait bait association association 4A u2af2-snw1-2 2 3 unspecified role unspecified role prey prey 4 unspecified role unspecified role bait bait 5 unspecified role unspecified role prey prey association association 4B snw1-u2af2 2 3 unspecified role unspecified role bait bait 4 unspecified role unspecified role prey prey physical association physical association 4B u2af1-u2af2-2 1 4 unspecified role unspecified role prey prey 5 unspecified role unspecified role bait bait physical association physical association 4A