mbinfo MBInfo http://www.mechanobio.info/ The cortactin-binding domain of WIP is essential for podosome formation and extracellular matrix degradation by murine dendritic cells. The cortactin-binding domain of WIP is essential for podosome formation and extracellular matrix degradation by murine dendritic cells. Eur. J. Cell Biol. (0171-9335) 2011 imex curation Banon-Rodriguez I., Monypenny J., Ragazzini C., Franco A., Calle Y., Jones G.E., Anton I.M. Host organism: dendritic cells from mouse spleen. The interactions of WIP with HS1 and WASP (Fig 3D) could not be curated since the source of the recombinant WIP was not specified and could not be traced. ianton@cnb.csic.es 15-Nov-2012: Contacted by pporras. Only protein-protein interactions mouse-dendritic cell Mouse dendritic cell dendritic_cell dendritic cell anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Banon-Rodriguez I., Monypenny J., Ragazzini C., Franco A., Calle Y., Jones G.E., Anton I.M. Host organism: dendritic cells from mouse spleen. The interactions of WIP with HS1 and WASP (Fig 3D) could not be curated since the source of the recombinant WIP was not specified and could not be traced. ianton@cnb.csic.es Accepted 2012-OCT-24 by ORCHARD 15-Nov-2012: Contacted by pporras. Eur. J. Cell Biol. (0171-9335) 2011 Only protein-protein interactions imex curation src8_mouse Src substrate cortactin Cttn Ems1 protein protein mouse Mus musculus Mouse MWKASAGHAVSITQDDGGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDRSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSSAVGFDYKERLAKHESQQDYAKGFGGKYGVQKDRMDKNASTFEEVVQVPSAYQKTVPIEAVTSKTSNIRANFENLAKEREQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKKQTPPASPSPQPIEDRPPSSPIYEDAAPFKAEPSYRGSEPEPEYSIEAAGIPEAGSQQGLTYTSEPVYETTEAPGHYQAEDDTYDGYESDLGITAIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ DIP protein Q60598 original sequence version: 136 DIP protein Q60598 original sequence version: 78 DIP protein Q60598 original sequence version: 135 8F5CA026ACCD6D4F mmp2_mouse 72 kDa type IV collagenase Mmp2 72 kDa gelatinase Gelatinase A Matrix metalloproteinase-2 protein protein mouse Mus musculus Mouse MEARVAWGALAGPLRVLCVLCCLLGRAIAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQGTSYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRNDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSHDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC C630A7DBDB272F02 cttn-mmp2-1 1 2 unspecified role unspecified role bait bait 3 unspecified role unspecified role prey prey physical association physical association Fig 2F. The Cortactin-WIP interaction was intact in the presence or absence of WIP (Fig 2F).