<?xml version='1.0' encoding='UTF-8'?>
<entrySet xmlns="http://psi.hupo.org/mi/mif300" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://psi.hupo.org/mi/mif300 https://raw.githubusercontent.com/HUPO-PSI/miXML/master/3.0/src/MIF300.xsd" level="3" version="0" minorVersion="0">
  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>UniProt</shortLabel>
        <fullName>UniProt</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0486" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-3989247" refType="identity" refTypeAc="MI:0356"/>
      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://www.uniprot.org</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="20657822" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6280711" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-17726" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion.</attribute>
            <attribute name="journal" nameAc="MI:0885">PLoS Pathog. (1553-7366)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2010</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Wang H., Ryu W.S.</attribute>
            <attribute name="data-processing" nameAc="MI:0633">Origin of constructs for CoIP confirmed by the authors (e-mail)</attribute>
            <attribute name="contact-email" nameAc="MI:0634">wsryu@yonsei.ac.kr</attribute>
            <attribute name="author-announcement">11-Oct-2012: Contacted by IntAct-Help.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="20657822" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-17726" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human-293</shortLabel>
              <fullName>Homo sapiens transformed primary embryonal kidney cells</fullName>
              <alias type="synonym" typeAc="MI:1041">Human</alias>
            </names>
            <cellType>
              <names>
                <shortLabel>293</shortLabel>
                <fullName>Transformed human primary embryonal kidney cells.</fullName>
              </names>
              <xref>
                <primaryRef db="cabri" dbAc="MI:0246" id="ACC 305" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="IA:0058" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-1782570" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-307626" refType="identity" refTypeAc="MI:0356"/>
              </xref>
              <attributeList>
                <attribute name="comment" nameAc="MI:0612">The Cell type named 293 is synonymous with HEK-293.</attribute>
              </attributeList>
            </cellType>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti tag coip</shortLabel>
            <fullName>anti tag coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti tag coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0007" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-90" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>anti tag western</shortLabel>
            <fullName>anti tag western blot</fullName>
            <alias type="synonym" typeAc="MI:1041">anti tag western</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0705" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-967832" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Wang H., Ryu W.S.</attribute>
          <attribute name="data-processing" nameAc="MI:0633">Origin of constructs for CoIP confirmed by the authors (e-mail)</attribute>
          <attribute name="contact-email" nameAc="MI:0634">wsryu@yonsei.ac.kr</attribute>
          <attribute name="accepted">Accepted 2012-SEP-06 by MGT</attribute>
          <attribute name="author-announcement">11-Oct-2012: Contacted by IntAct-Help.</attribute>
          <attribute name="journal" nameAc="MI:0885">PLoS Pathog. (1553-7366)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2010</attribute>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959"/>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>ikke_human</shortLabel>
          <fullName>Inhibitor of nuclear factor kappa-B kinase subunit epsilon</fullName>
          <alias type="gene name" typeAc="MI:0301">IKBKE</alias>
          <alias type="gene name synonym" typeAc="MI:0302">IKKE</alias>
          <alias type="gene name synonym" typeAc="MI:0302">IKKI</alias>
          <alias type="gene name synonym" typeAc="MI:0302">KIAA0151</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Inducible I kappa-B kinase</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q14164" version="SP_77" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q3KR43" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5JTS6" version="SP_77" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DT78" version="SP_113" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000464030" version="SP_208" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q3B754" version="SP_131" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-307369" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001180250.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001180251.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_054721.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000263528" version="SP_208" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000581977" version="SP_208" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000187" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004674" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004704" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006955" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008384" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008630" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010467" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010884" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016605" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0018105" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019903" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031966" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034340" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035456" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0036435" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043254" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048255" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051091" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060340" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097400" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0098586" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR041087" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR041309" version="SP_208"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q14164" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4755510" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013973" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-918233" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-933541" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-936440" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-936964" version="SP_208"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005273413.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-27530N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLRKLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYLHPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTEKPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFAETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCVLEPSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKFVPKVDLQADYNTAKGVLGAGYQALRLARALLDGQELMFRGLHWVMEVLQATCRRTLEVARTSLLYLSSSLGTERFSSVAGTPEIQELKAAAELRSRLRTLAEVLSRCSQNITETQESLSSLNRELVKSRDQVHEDRSIQQIQCCLDKMNFIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQKYQASLVTHGKRMRVVHETRNHLRLVGCSVAACNTEAQGVQESLSKLLEELSHQLLQDRAKGAQASPPPIAPYPSPTRKDLLLHMQELCEGMKLLASDLLDNNRIIERLNRVPAPPDV</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q14164 original sequence version: 139</attribute>
          <attribute name="remark-internal">DIP protein Q14164 original sequence version: 148</attribute>
          <attribute name="remark-internal">DIP protein Q14164 original sequence version: 108</attribute>
          <attribute name="crc64">3E5FBE5840734D81</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>ddx3x_human</shortLabel>
          <fullName>ATP-dependent RNA helicase DDX3X</fullName>
          <alias type="gene name" typeAc="MI:0301">DDX3X</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DBX</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DDX3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DEAD box protein 3, X-chromosomal</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Helicase-like protein 2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DEAD box, X isoform</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CAP-Rf</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="O00571" version="SP_85" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O15536" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K538" version="SP_128" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4E3E8" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000478443" version="SP_236" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000486516" version="SP_236" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000486720" version="SP_236" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000487224" version="SP_236" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000494040" version="SP_236" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-353779" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001347.3"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001180345.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001180346.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000215301" version="SP_236" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000478993" version="SP_236" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000629496" version="SP_236" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000629785" version="SP_236" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000630255" version="SP_236" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000644876" version="SP_236" refType="transcript"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003723" version="SP_236"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_236"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_236"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045727" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045948" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048027" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0055088" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071243" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071470" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071651" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071902" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072559" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090263" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097193" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0098586" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0140603" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1900087" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1900227" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901223" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901224" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901985" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1902042" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1902523" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1903608" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1904813" version="SP_236"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001243" version="SP_236"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000629" version="SP_236"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001650" version="SP_236"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011545" version="SP_236"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014001" version="SP_236"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014014" version="SP_236"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027417" version="SP_236"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="O00571" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2I4I" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2JGN" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3JRV" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4O2C" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4O2E" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4O2F" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4PX9" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4PXA" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E7I" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E7J" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E7M" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6CZ5" version="SP_236"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6O5F" version="SP_236"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6798695" version="SP_236"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-27551N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein O00571 original sequence version: 116</attribute>
          <attribute name="remark-internal">DIP protein O00571 original sequence version: 123</attribute>
          <attribute name="crc64">7074D2B8A6EBBF09</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4" imexId="IM-17726-1">
        <names>
          <shortLabel>ikbke-ddx3x</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-6280752" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-17726-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>nucl transfection</shortLabel>
                  <fullName>nucleic acid transfection</fullName>
                  <alias type="synonym" typeAc="MI:1041">nucl transfection</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0312" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537704" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="6">
                <names>
                  <shortLabel>regiom</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-6280759" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>ha tag</shortLabel>
                    <fullName>ha tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">YPYDVPDYA epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">YPYDVPDYA epitope tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0520" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456513" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
          <participant id="7">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>nucl transfection</shortLabel>
                  <fullName>nucleic acid transfection</fullName>
                  <alias type="synonym" typeAc="MI:1041">nucl transfection</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0312" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537704" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="8">
                <names>
                  <shortLabel>region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-6280756" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>flag tag</shortLabel>
                    <fullName>flag tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">FLAG-tagged</alias>
                    <alias type="go synonym" typeAc="MI:0303">FLAG</alias>
                    <alias type="go synonym" typeAc="MI:0303">DYKDDDDKV epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">DYKDDDDKV epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">FLAG</alias>
                    <alias type="synonym" typeAc="MI:1041">FLAG-tagged</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0518" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456503" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">6c</attribute>
          <attribute name="antagonist" nameAc="MI:0626">Hepatitis B virus polymerase</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>