UniProt UniProt http://www.uniprot.org Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin. Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin. J. Neurosci. (0270-6474) 2008 mimix curation Zhu D., Yang Z., Luo Z., Luo S., Xiong W.C., Mei L. lmei@mcg.edu 18-Dec-2012: Contacted by IntAct-Help. human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Zhu D., Yang Z., Luo Z., Luo S., Xiong W.C., Mei L. lmei@mcg.edu Accepted 2012-NOV-15 by ORCHARD 18-Dec-2012: Contacted by IntAct-Help. J. Neurosci. (0270-6474) 2008 mimix curation Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin. Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin. J. Neurosci. (0270-6474) 2008 mimix curation Zhu D., Yang Z., Luo Z., Luo S., Xiong W.C., Mei L. lmei@mcg.edu 18-Dec-2012: Contacted by IntAct-Help. in vitro In vitro elisa enzyme linked immunosorbent assay ELISA ELISA elisa antibody detection identification by antibody antibody detection Zhu D., Yang Z., Luo Z., Luo S., Xiong W.C., Mei L. lmei@mcg.edu Accepted 2012-NOV-15 by ORCHARD 18-Dec-2012: Contacted by IntAct-Help. J. Neurosci. (0270-6474) 2008 mimix curation Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin. Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin. J. Neurosci. (0270-6474) 2008 mimix curation Zhu D., Yang Z., Luo Z., Luo S., Xiong W.C., Mei L. lmei@mcg.edu 18-Dec-2012: Contacted by IntAct-Help. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Zhu D., Yang Z., Luo Z., Luo S., Xiong W.C., Mei L. lmei@mcg.edu Accepted 2012-NOV-15 by ORCHARD 18-Dec-2012: Contacted by IntAct-Help. J. Neurosci. (0270-6474) 2008 mimix curation Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin. Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin. J. Neurosci. (0270-6474) 2008 mimix curation Zhu D., Yang Z., Luo Z., Luo S., Xiong W.C., Mei L. lmei@mcg.edu 18-Dec-2012: Contacted by IntAct-Help. mouse-c2c12 Mouse C3H muscle myoblast c2c12 Mouse C3H muscle myoblast anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhu D., Yang Z., Luo Z., Luo S., Xiong W.C., Mei L. lmei@mcg.edu Accepted 2012-NOV-15 by ORCHARD 18-Dec-2012: Contacted by IntAct-Help. J. Neurosci. (0270-6474) 2008 mimix curation Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin. Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin. J. Neurosci. (0270-6474) 2008 mimix curation Zhu D., Yang Z., Luo Z., Luo S., Xiong W.C., Mei L. lmei@mcg.edu 18-Dec-2012: Contacted by IntAct-Help. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Zhu D., Yang Z., Luo Z., Luo S., Xiong W.C., Mei L. lmei@mcg.edu Accepted 2012-NOV-15 by ORCHARD 18-Dec-2012: Contacted by IntAct-Help. J. Neurosci. (0270-6474) 2008 mimix curation musk_mouse Muscle, skeletal receptor tyrosine-protein kinase Musk Nsk2 Muscle-specific tyrosine-protein kinase receptor protein protein mouse Mus musculus Mouse MRELVNIPLLQMLTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCIANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDNALRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKLVKLEVEVFARILRAPESHNVTFGSFVTLRCTAIGIPVPTISWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATVSIAEWSKSQKDSQGYCAQYRGEVCDAVLAKDALVFFNTSYRDPEDAQELLIHTAWNELKAVSPLCRPAAEALLCNHLFQECSPGVVPTPMPICREYCLAVKELFCAKEWQAMEGKAHRGLYRSGMHLLPVPECSKLPSMHRDPTACTRLPYLDYKKENITTFPSITSSRPSADIPNLPASTSSFAVSPAYSMTVIISIVSSFALFALLTIATLYCCRRRKEWKNKKRESTAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGETMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMRLCWSKLPADRPSFCSIHRILQRMCERAEGTVGV nsf_mouse Vesicle-fusing ATPase Nsf Skd2 N-ethylmaleimide-sensitive fusion protein Vesicular-fusion protein NSF Suppressor of K(+) transport growth defect 2 protein protein mouse Mus musculus Mouse MAGRTMQAARCPTDELSLSNCAVVNEKDFQSGQHVMVRTSPNHKYIFTLRTHPSVVPGCIAFSLPQRKWAGLSIGQDIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMDPSILKGEPASGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALMREEGASPLDFD BE55AD0056AD5585 q61006-3 Muscle, skeletal receptor tyrosine-protein kinase Musk Nsk2 Muscle-specific tyrosine-protein kinase receptor protein protein mouse Mus musculus Mouse MRELVNIPLLQMLTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCIANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDNALRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKLVKLEVEVFARILRAPESHNVTFGSFVTLRCTAIGIPVPTISWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATVSIAEWSKSQKDSQGYCAQYRGEGVLMQGPGEKMLLVFLPTTSYRDPEDAQELLIHTAWNELKAVSPLCRPAAEALLCNHLFQECSPGVVPTPMPICREYCLAVKELFCAKEWQAMEGKAHRGLYRSGMHLLPVPECSKLPSMHRDPTACTRLPYLDYKKENITTFPSITSSRPSADIPNLPASTSSFAVSPAYSMTVIISIVSSFALFALLTIATLYCCRRRKEWKNKKRESTAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGETMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMRLCWSKLPADRPSFCSIHRILQRMCERAEGTVGV No experimental confirmation available. AA8D8D17E2F04722 musk-nsf 3 8 unspecified role unspecified role bait bait cytoplasmic region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 7 unspecified role unspecified role prey prey physical association physical association No Figure musk-nsf-1 5 7 unspecified role unspecified role prey prey 8 unspecified role unspecified role bait bait physical association physical association 3A, 3B, 3C musk-nsf-5 2 8 unspecified role unspecified role bait bait 7 unspecified role unspecified role prey prey direct interaction direct interaction 3D musk-nsf-3 1 8 unspecified role unspecified role bait bait 7 unspecified role unspecified role prey prey physical association physical association 4A nsf-musk 1 8 unspecified role unspecified role prey prey 7 unspecified role unspecified role bait bait physical association physical association 4B nsf-musk-2 4 6 unspecified role unspecified role prey prey 7 unspecified role unspecified role bait bait physical association physical association 7A