<?xml version='1.0' encoding='UTF-8'?>
<entrySet xmlns="http://psi.hupo.org/mi/mif300" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://psi.hupo.org/mi/mif300 https://raw.githubusercontent.com/HUPO-PSI/miXML/master/3.0/src/MIF300.xsd" level="3" version="0" minorVersion="0">
  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>mpidb</shortLabel>
        <fullName>The Microbial Protein Interaction Database</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0903" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6390654" refType="identity" refTypeAc="MI:0356"/>
      </xref>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Maltose binding protein (MalE) interacts with periplasmic loops P2 and P1 respectively of the MalFG subunits of the maltose ATP binding cassette transporter (MalFGK(2)) from Escherichia coli/Salmonella during the transport cycle.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="17961142" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6400976" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-18150" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Maltose binding protein (MalE) interacts with periplasmic loops P2 and P1 respectively of the MalFG subunits of the maltose ATP binding cassette transporter (MalFGK(2)) from Escherichia coli/Salmonella during the transport cycle.</attribute>
            <attribute name="journal" nameAc="MI:0885">Mol. Microbiol. (0950-382X)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2007</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Daus M.L., Berendt S., Wuttge S., Schneider E.</attribute>
            <attribute name="author-announcement">04-Feb-2013: Contacted by IntAct-Help.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-18150" refType="imex-primary" refTypeAc="MI:0662"/>
          <secondaryRef db="pubmed" dbAc="MI:0446" id="17961142" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>crosslink</shortLabel>
            <fullName>cross-linking study</fullName>
            <alias type="synonym" typeAc="MI:1041">crosslink</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0030" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1049" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>ms participant</shortLabel>
            <fullName>Identification by mass spectrometry</fullName>
            <alias type="synonym" typeAc="MI:1041">ms participant</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0427" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608794" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Daus M.L., Berendt S., Wuttge S., Schneider E.</attribute>
          <attribute name="accepted">Accepted 2013-JAN-04 by ORCHARD</attribute>
          <attribute name="author-announcement">04-Feb-2013: Contacted by IntAct-Help.</attribute>
          <attribute name="journal" nameAc="MI:0885">Mol. Microbiol. (0950-382X)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2007</attribute>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959"/>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>malf_ecoli</shortLabel>
          <fullName>Maltose/maltodextrin transport system permease protein MalF</fullName>
          <alias type="gene name" typeAc="MI:0301">malF</alias>
          <alias type="locus name" typeAc="MI:0305">b4033</alias>
          <alias type="locus name" typeAc="MI:0305">JW3993</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P02916" version="SP_74" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q2M6S1" version="SP_74" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensemblbacteria" id="AAC77003" version="SP_182" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="BAE78035" version="SP_182" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1118919" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="AAC77003" version="SP_182" refType="transcript"/>
          <secondaryRef db="ensemblbacteria" id="b4033" version="SP_182" refType="gene"/>
          <secondaryRef db="ensemblbacteria" id="BAE78035" version="SP_182" refType="gene"/>
          <secondaryRef db="ensemblbacteria" id="BAE78035" version="SP_182" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_182"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" version="SP_182"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006974" version="SP_182"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015423" version="SP_182"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015768" version="SP_182"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" version="SP_182"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042956" version="SP_182"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043190" version="SP_182"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990060" version="SP_182"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000515" version="SP_182"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029345" version="SP_182"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR030156" version="SP_182"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035277" version="SP_182"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035906" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2R6G" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3FH6" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PUV" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PUW" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PUX" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PUY" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PUZ" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PV0" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RLF" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JBW" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KHZ" version="SP_182"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KI0" version="SP_182"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_418457.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="WP_001297290.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-10142N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="83333">
          <names>
            <shortLabel>ecoli</shortLabel>
            <fullName>Escherichia coli (strain K12)</fullName>
          </names>
        </organism>
        <sequence>MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKATRMKFD</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P02916 original sequence version: 123</attribute>
          <attribute name="remark-internal">DIP protein P02916 original sequence version: 114</attribute>
          <attribute name="crc64">895CEA1986CE5C0B</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>male_salty</shortLabel>
          <fullName>Maltose/maltodextrin-binding periplasmic protein</fullName>
          <alias type="gene name" typeAc="MI:0301">malE</alias>
          <alias type="gene name synonym" typeAc="MI:0302">MMBP</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Maltodextrin-binding protein</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Maltose-binding protein</alias>
          <alias type="locus name" typeAc="MI:0305">STM4229</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P19576" version="SP_95" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="AAL23053" version="SP_143" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6470151" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="AAL23053" version="SP_143" refType="transcript"/>
          <secondaryRef db="ensemblbacteria" id="STM4229" version="SP_143" refType="gene"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015144" version="SP_143"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015768" version="SP_143"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042597" version="SP_143"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042956" version="SP_143"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0055052" version="SP_143"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901982" version="SP_143"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_463094.3"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006060"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006061"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3JYR"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006059"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6L0Z"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6L3E"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="99287">
          <names>
            <shortLabel>salty</shortLabel>
            <fullName>Salmonella typhimurium</fullName>
          </names>
        </organism>
        <sequence>MKIKTGVGILALSALTTMMISAPALAKIEEGKLVIWINGDKGYNGLAEVGKKFEQDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEVTPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLVPNPPKTWEEIPALDKELKVKGKSAIMFNLQEPYFTWPLIAADGGYAFKFENGKYDVKDVGVDNAGAKAGLTFLIDMIKNKNMSADTDYSIAEAAFNKGETAMTINGPWAWSNIDKSKVNYGVTLLPTFKGKPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDQGLEAVNKDKPLGAVALKSFQEQLAKDPRIAATMDNAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALKDAQSRITK</sequence>
        <attributeList>
          <attribute name="crc64">2D76BAD17BC502A9</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>malg_ecoli</shortLabel>
          <fullName>Maltose/maltodextrin transport system permease protein MalG</fullName>
          <alias type="locus name" typeAc="MI:0305">JW3992</alias>
          <alias type="locus name" typeAc="MI:0305">b4032</alias>
          <alias type="gene name" typeAc="MI:0301">malG</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P68183" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="AAC77002" version="SP_130" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="BAE78034" version="SP_130" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P07622" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q2M6S2" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6400985" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="WP_001252058.1"/>
          <secondaryRef db="ensemblbacteria" id="AAC77002" version="SP_130" refType="transcript"/>
          <secondaryRef db="ensemblbacteria" id="b4032" version="SP_130" refType="gene"/>
          <secondaryRef db="ensemblbacteria" id="BAE78034" version="SP_130" refType="gene"/>
          <secondaryRef db="ensemblbacteria" id="BAE78034" version="SP_130" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_130"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" version="SP_130"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015423" version="SP_130"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015768" version="SP_130"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" version="SP_130"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042956" version="SP_130"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043190" version="SP_130"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990060" version="SP_130"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000515" version="SP_130"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035906" version="SP_130"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2R6G" version="SP_130"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3FH6" version="SP_130"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PUV" version="SP_130"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PUW" version="SP_130"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PUX" version="SP_130"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PUY" version="SP_130"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PUZ" version="SP_130"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PV0" version="SP_130"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RLF" version="SP_130"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JBW" version="SP_130"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KI0" version="SP_130"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_418456.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-59709N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="83333">
          <names>
            <shortLabel>ecoli</shortLabel>
            <fullName>Escherichia coli (strain K12)</fullName>
          </names>
        </organism>
        <sequence>MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNFATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVALSTTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHGGVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITIVFLLAQRWLVNGLTAGGVKG</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P68183 original sequence version: 76</attribute>
          <attribute name="remark-internal">DIP protein P68183 original sequence version: 67</attribute>
          <attribute name="crc64">E54418E91E344A29</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="5" imexId="IM-18150-1">
        <names>
          <shortLabel>male-malg</shortLabel>
        </names>
        <xref>
          <primaryRef db="mpidb" dbAc="MI:0903" id="MPIDB-INT-1095" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6400992" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-18150-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="6">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="7">
                <names>
                  <shortLabel>P19576:p.Ser237Cys</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-6470171" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>mutation</shortLabel>
                    <fullName>mutation</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456558" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="237"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="237"/>
                    <resultingSequence>
                      <originalSequence>S</originalSequence>
                      <newSequence>C</newSequence>
                    </resultingSequence>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">Wed May 02 19:12:21 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser237cys'</attribute>
                  <attribute name="remark-internal">Tue Jun 30 16:36:25 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser237Cys'</attribute>
                </attributeList>
              </feature>
              <feature id="8">
                <names>
                  <shortLabel>P19576:p.Gly39Cys</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-6470169" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>mutation</shortLabel>
                    <fullName>mutation</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456558" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="39"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="39"/>
                    <resultingSequence>
                      <originalSequence>G</originalSequence>
                      <newSequence>C</newSequence>
                    </resultingSequence>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">Wed May 02 14:46:11 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gly39cys'</attribute>
                  <attribute name="remark-internal">Tue Jun 30 17:38:33 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gly39Cys'</attribute>
                </attributeList>
              </feature>
              <feature id="9">
                <names>
                  <shortLabel>P19576:p.Phe243Cys</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-6470173" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>mutation</shortLabel>
                    <fullName>mutation</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456558" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="243"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="243"/>
                    <resultingSequence>
                      <originalSequence>F</originalSequence>
                      <newSequence>C</newSequence>
                    </resultingSequence>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">Wed May 02 20:02:05 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe243cys'</attribute>
                  <attribute name="remark-internal">Tue Jun 30 16:24:57 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe243Cys'</attribute>
                </attributeList>
              </feature>
            </featureList>
          </participant>
          <participant id="10">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="11">
                <names>
                  <shortLabel>P68183:p.Pro78Cys</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-6470175" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>mutation</shortLabel>
                    <fullName>mutation</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456558" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="78"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="78"/>
                    <resultingSequence>
                      <originalSequence>P</originalSequence>
                      <newSequence>C</newSequence>
                    </resultingSequence>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">Wed May 02 16:08:07 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro78cys'</attribute>
                  <attribute name="remark-internal">Tue Jun 30 17:18:40 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Pro78Cys'</attribute>
                </attributeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Figs 3-5</attribute>
        </attributeList>
      </interaction>
      <interaction id="12" imexId="IM-18150-2">
        <names>
          <shortLabel>male-malf</shortLabel>
        </names>
        <xref>
          <primaryRef db="mpidb" dbAc="MI:0903" id="MPIDB-INT-1094" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6400997" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-18150-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="13">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="14">
                <names>
                  <shortLabel>P02916:p.Ser252Cys</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-6470194" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>mutation</shortLabel>
                    <fullName>mutation</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456558" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="252"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="252"/>
                    <resultingSequence>
                      <originalSequence>S</originalSequence>
                      <newSequence>C</newSequence>
                    </resultingSequence>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">Wed May 02 17:39:04 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser252cys'</attribute>
                  <attribute name="remark-internal">Tue Jun 30 17:05:03 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser252Cys'</attribute>
                </attributeList>
              </feature>
              <feature id="15">
                <names>
                  <shortLabel>P02916:p.Ser205Cys</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-6470190" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>mutation</shortLabel>
                    <fullName>mutation</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456558" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="205"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="205"/>
                    <resultingSequence>
                      <originalSequence>S</originalSequence>
                      <newSequence>C</newSequence>
                    </resultingSequence>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">Wed May 02 17:13:02 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser205cys'</attribute>
                  <attribute name="remark-internal">Tue Jun 30 17:36:09 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser205Cys'</attribute>
                </attributeList>
              </feature>
            </featureList>
          </participant>
          <participant id="16">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="17">
                <names>
                  <shortLabel>P19576:p.Phe243Cys</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-6470182" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>mutation</shortLabel>
                    <fullName>mutation</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456558" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="243"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="243"/>
                    <resultingSequence>
                      <originalSequence>F</originalSequence>
                      <newSequence>C</newSequence>
                    </resultingSequence>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">Wed May 02 18:08:13 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe243cys'</attribute>
                  <attribute name="remark-internal">Tue Jun 30 20:25:03 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe243Cys'</attribute>
                </attributeList>
              </feature>
              <feature id="18">
                <names>
                  <shortLabel>P19576:p.Gly39Cys</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-6470177" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>mutation</shortLabel>
                    <fullName>mutation</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456558" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="39"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="39"/>
                    <resultingSequence>
                      <originalSequence>G</originalSequence>
                      <newSequence>C</newSequence>
                    </resultingSequence>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">Wed May 02 19:20:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gly39cys'</attribute>
                  <attribute name="remark-internal">Tue Jun 30 19:53:45 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gly39Cys'</attribute>
                </attributeList>
              </feature>
              <feature id="19">
                <names>
                  <shortLabel>P19576:p.Ser237Cys</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-6470180" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>mutation</shortLabel>
                    <fullName>mutation</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456558" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="237"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="237"/>
                    <resultingSequence>
                      <originalSequence>S</originalSequence>
                      <newSequence>C</newSequence>
                    </resultingSequence>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">Wed May 02 15:54:55 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser237cys'</attribute>
                  <attribute name="remark-internal">Tue Jun 30 18:38:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser237Cys'</attribute>
                </attributeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Figs 3-5</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>