UniProt UniProt http://www.uniprot.org Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. J. Biol. Chem. (0021-9258) 2006 mimix curation Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr 19-Jun-2012: Contacted by JYOTI. in vitro In vitro pull down pull down weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr Accepted 2012-MAR-27 by MGT 19-Jun-2012: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2006 mimix curation Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. J. Biol. Chem. (0021-9258) 2006 mimix curation Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr 19-Jun-2012: Contacted by JYOTI. in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr Accepted 2012-MAR-27 by MGT 19-Jun-2012: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2006 mimix curation Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. J. Biol. Chem. (0021-9258) 2006 mimix curation Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr 19-Jun-2012: Contacted by JYOTI. mouse-nih_3t3 Mus musculus Swiss NIH 3t3 embryo fibroblast cells nih_3t3 Mouse Swiss NIH embryo contact inhibited fibroblast cells confocal microscopy confocal microscopy tag fluorescence tag visualisation by fluorescence tag fluorescence Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr Accepted 2012-MAR-27 by MGT 19-Jun-2012: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2006 mimix curation Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. J. Biol. Chem. (0021-9258) 2006 mimix curation Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr 19-Jun-2012: Contacted by JYOTI. mouse-nih_3t3 Mus musculus Swiss NIH 3t3 embryo fibroblast cells nih_3t3 Mouse Swiss NIH embryo contact inhibited fibroblast cells anti bait coip anti bait coimmunoprecipitation anti bait coip anti tag western anti tag western blot anti tag western Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr Accepted 2012-MAR-27 by MGT 19-Jun-2012: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2006 mimix curation Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. J. Biol. Chem. (0021-9258) 2006 mimix curation Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr 19-Jun-2012: Contacted by JYOTI. human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. anti bait coip anti bait coimmunoprecipitation anti bait coip anti tag western anti tag western blot anti tag western Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr Accepted 2012-MAR-27 by MGT 19-Jun-2012: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2006 mimix curation Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. J. Biol. Chem. (0021-9258) 2006 mimix curation Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr 19-Jun-2012: Contacted by JYOTI. human-mcf7 Homo sapiens mammary carcinoma cells mcf7 mammary carcinoma cells anti bait coip anti bait coimmunoprecipitation anti bait coip anti tag western anti tag western blot anti tag western Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr Accepted 2012-MAR-27 by MGT 19-Jun-2012: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2006 mimix curation Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. J. Biol. Chem. (0021-9258) 2006 mimix curation Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr 19-Jun-2012: Contacted by JYOTI. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr Accepted 2012-MAR-27 by MGT HeLa cDNA library J. Biol. Chem. (0021-9258) 2006 mimix curation Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. J. Biol. Chem. (0021-9258) 2006 mimix curation Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr 19-Jun-2012: Contacted by JYOTI. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr Accepted 2012-MAR-27 by MGT 19-Jun-2012: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2006 mimix curation Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. J. Biol. Chem. (0021-9258) 2006 mimix curation Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr 19-Jun-2012: Contacted by JYOTI. human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 anti bait coip anti bait coimmunoprecipitation anti bait coip anti tag western anti tag western blot anti tag western Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr Accepted 2012-MAR-27 by MGT 19-Jun-2012: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2006 mimix curation Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. J. Biol. Chem. (0021-9258) 2006 mimix curation Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr 19-Jun-2012: Contacted by JYOTI. human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Cho Y.S., Kim E.J., Park U.H., Sin H.S., Um S.J. Assays were performed in the presence of cognate ligands, (except RARa/Ncor1 interaction.) Origin of SRC-1/NCOA1 according given seq length of used constructs umsj@sejong.ac.kr Accepted 2012-MAR-27 by MGT 19-Jun-2012: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2006 mimix curation ncor1_human Nuclear receptor corepressor 1 NCOR1 KIAA1047 protein protein human Homo sapiens Human MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQQQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD DIP protein O75376 original sequence version: 186 DIP protein O75376 original sequence version: 75 DIP protein O75376 original sequence version: 153 DIP protein O75376 original sequence version: 147 DIP protein O75376 original sequence version: 112 DIP protein O75376-1 original sequence version: 111 DIP protein O75376 original sequence version: 146 1647FE060373A125 gcr_human Glucocorticoid receptor Nuclear receptor subfamily 3 group C member 1 NR3C1 GRL protein protein human Homo sapiens Human MDSKESLTPGREENPSSVLAQERGDVMDFYKTLRGGATVKVSASSPSLAVASQSDSKQRRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLSSGETDLKLLEESIANLNRSTSVPENPKSSASTAVSAAPTEKEFPKTHSDVSSEQQHLKGQTGTNGGNVKLYTTDQSTFDILQDLEFSSGSPGKETNESPWRSDLLIDENCLLSPLAGEDDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSPSNVTLPQVKTEKEDFIELCTPGVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK C5C90C9A5DD16AAB rarb_mouse Retinoic acid receptor beta Rarb Nr1b2 Nuclear receptor subfamily 1 group B member 2 protein protein mouse Mus musculus Mouse MSTSSHACPVPAVRGHMTHYPAAPYPLLFPPVIRGLSLPPLHGLHGHPPPSGCSTPSPASVGQACQRTTGGSQFAASTKWTPSLNAAIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNIAEHSPSVSPSSVENSGVSQSPLLQ 48E78E6C7D012515 thb_chick Thyroid hormone receptor beta THRB C-ERBA-BETA NR1A2 Nuclear receptor subfamily 1 group A member 2 protein protein chick Gallus gallus (Chicken) Chicken MSGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYEGKCVIDKVTRNQCQECRFKKCIFVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKTIGHKPEPTDEEWELIKIVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLVCVERIEKCQEGFLLAFEHYINYRKHHVAHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED 36FC16B41383138F asxl1_human Polycomb group protein ASXL1 ASXL1 KIAA0978 Additional sex combs-like protein 1 protein protein human Homo sapiens Human MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKDALQWSRHPATVEGEEPEDTADVESCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLSNPRDSYRASSQANKQKKKTGVMLPRVVLTPLKVNGAHVESASGFSGCHADGESGSPSSSSSGSLALGSAAIRGQAEVTQDPAPLLRGFRKPATGQMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQNVGQEEAEIKSGLCVPGESVRIQRGPATRQRDGHFKKRSRPDLRTRARRNLYKKQESEQAGVAKDAKSVASDVPLYKDGEAKTDPAGLSSPHLPGTSSAAPDLEGPEFPVESVASRIQAEPDNLARASASPDRIPSLPQETVDQEPKDQKRKSFEQAASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPTTESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARREDLPSLRKEESCLLQRATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVEQPQLHPDVRTECESGTTSWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPTMKDPVNVTPSSTPESSPTDCLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSLHWIPIPSNDEVVKQPKPESREHIPSVEPQVGEEWEKAAPTPPALPGDLTAEEGLDPLDSLTSLWTVPSRGGSDSNGSYCQQVDIEKLKINGDSEALSPHGESTDTASDFEGHLTEDSSEADTREAAVTKGSSVDKDEKPNWNQSAPLSKVNGDMRLVTRTDGMVAPQSWVSRVCAVRQKIPDSLLLASTEYQPRAVCLSMPGSSVEATNPLVMQLLQGSLPLEKVLPPAHDDSMSESPQVPLTKDQSHGSLRMGSLHGLGKNSGMVDGSSPSSLRALKEPLLPDSCETGTGLARIEATQAPGAPQKNCKAVPSFDSLHPVTNPITSSRKLEEMDSKEQFSSFSCEDQKEVRAMSQDSNSNAAPGKSPGDLTTSRTPRFSSPNVISFGPEQTGRALGDQSNVTGQGKKLFGSGNVAATLQRPRPADPMPLPAEIPPVFPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEKTFVGGPLKANAENRKATGHSPLELVGHLEGMPFVMDLPFWKLPREPGKGLSEPLEPSSLPSQLSIKQAFYGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSLQMFTDSSTVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR DIP protein Q8IXJ9 original sequence version: 71 DIP protein Q8IXJ9 original sequence version: 91 8FCE072F3295AA34 rarb_human Retinoic acid receptor beta RARB HAP NR1B2 Nuclear receptor subfamily 1 group B member 2 RAR-epsilon HBV-activated protein protein protein human Homo sapiens Human MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPATIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ 8813263AD0495D5A rxra_mouse Retinoic acid receptor RXR-alpha Rxra Nr2b1 Retinoid X receptor alpha Nuclear receptor subfamily 2 group B member 1 protein protein mouse Mus musculus Mouse MDTKHFLPLDFSTQVNSSSLNSPTGRGSMAVPSLHPSLGPGIGSPLGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFGTGSPQLNSPMNPVSSTEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVEKILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQAT 0AF62396BCDC87DB esr1_human Estrogen receptor ESR1 ESR NR3A1 Estradiol receptor ER-alpha Nuclear receptor subfamily 3 group A member 1 protein protein human Homo sapiens Human MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV DIP protein P03372 original sequence version: 214 DIP protein P03372 original sequence version: 139 DIP protein P03372 original sequence version: 167 5455C57AB0CCCAA7 asxl1_mouse Polycomb group protein ASXL1 Asxl1 Kiaa0978 Additional sex combs-like protein 1 protein protein mouse Mus musculus Mouse MKDKQKRKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKDAVQWSRNAATVDGDEPEDSADVESCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLSNPRDSHRASSQANKQKKRTGVMLPRVVLTPLKVNGAHVEPASGFSGRHADGESGSPSSSSSGSLALGNSAIRGQAEVTRDPAPLLRGFRKPATGQMKRNRGEEVDFETPGSILVNTNLRALINSRTFHALPLHFQQQLLLLLPEVDRQVGTDGLLRLSGSALNNEFFTHAAQSWRERLADGEFTHEMQVRLRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQKEVQEEAKVKSGLCVSGESVRPQRGPNTRQRDGHFKKRSRPDLRTRSRRNIYKKQEPEQAGVAKDASAAPDVSLSKDTKTDLAGVNSTPGPDVSSATSGQEGPKCPSEPVASQIQAERDNLACASASPDRIPTLPQDTVDQETKDQKRKSFEQEASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVAKGRPTYQICPRIVPITESSCRGWTGARTLADIKARALQARGARGYHCNRETATTAIGGGGGPGGGGSGAIDEGGGRDSSSGDGSEACGHPEPRGAPSTSGESASDLQRTQLLPPCPLNGEHTPAEAAMPRARREDSASLRKEESCLLKRVPGVLTSGLEDASQPPIAPTGDQPCQALPPLSSQTPVAEMLTEQPKLLLDDRTECESSREDQGPTIPSESSSGRFPLGDLLGGGSDQAFDNMKEPVSMTPTFISELSLANYLQDRPDDDGLGLGATGLLIRESSRQEALTEAFASGSPTSWVPILSNYEVIKTSDPESRENIPCPEPQDEKEWERAVPLIAATESVPQPESCISHWTPPPAAVGSTGSDSEQVDLERLEMNGISEAPSPHSESTDTASDSEGHLSEDSSEVDASEVTVVKGSLGGDEKQDWDPSASLSKVNNDLSVLTRTGGVAASQSWVSRVCSVPHKIPDSLLLSSTECQPRSVCPLRPGSSVEVTNPLVMHLLHGNLPLEKVLPPGHRSSRLESSQLPLREQSQDRGTLQGTGENNRLAARINPGSAQTLKESILAQSYGASAGLVRAMASKAPAMSQKIAKMVTSLDSQHPETELTPSSGNLEEIDSKEHLSSFLCEEQKEGHSLSQGSDPGAAPGQCLGDHTTSKVPCFSSTNVSLSFGSEQTDGTLSDQNNAGGHEKKLFGPGNTVTTLQCPRSEEQTPLPAEVPPVFPSRKIEPSKNSVSGGVQTTRENRMPKPPPVSADSIKTEQTFLRDPIKADAENRKAAGYSSLELVGHLQGMPFVVDLPFWKLPREPGKGFSQPLEPSSIPSQLNIKQALYGKLSKLQLSPTSFNYSSSSATFPKGLAGGVVQLSHKASFGTGHTASLSLQMFADSSAVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR 20D9FBE9D4CF9E74 rxra_human Retinoic acid receptor RXR-alpha RXRA NR2B1 Retinoid X receptor alpha Nuclear receptor subfamily 2 group B member 1 protein protein human Homo sapiens Human MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT DIP protein P19793 original sequence version: 177 DIP protein P19793 original sequence version: 107 DIP protein P19793 original sequence version: 153 DIP protein P19793 original sequence version: 131 DIP protein P19793 original sequence version: 136 DIP protein P19793 original sequence version: 169 DIP protein P19793 original sequence version: 161 DIP protein P19793 original sequence version: 139 7F952B580AD84C42 rara_human Retinoic acid receptor alpha RARA NR1B1 Nuclear receptor subfamily 1 group B member 1 protein protein human Homo sapiens Human MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP DIP protein P10276 original sequence version: 190 DIP protein P10276 original sequence version: 118 DIP protein P10276 original sequence version: 162 DIP protein P10276-1 original sequence version: 143 DIP protein P10276 original sequence version: 200 DIP protein P10276-1 original sequence version: 152 E8D1CF9A1E57CB99 ncoa1_human Nuclear receptor coactivator 1 Steroid receptor coactivator 1 RIP160 Protein Hin-2 Renal carcinoma antigen NY-REN-52 NCOA1 SRC1 BHLHE74 Class E basic helix-loop-helix protein 74 protein protein human Homo sapiens Human MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINRQQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTGISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDNSSSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDSASTSVSVTGQVQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVKVEKKEQMDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQFDQLLPTLEKAAQLPGLCETDRMDGAVTSVTIKSEILPASLQSATARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSERFPPQQATPPLIMEERPNLYSQPYSSPSPTANLPSPFQGMVRQKPSLGTMPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILNQFAATAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAMLMRQQSFGNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLANRNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPIPPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVSMAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTEADGTQQVQQVQVFADVQCTVNLVGGDPYLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE DIP protein Q15788-1 original sequence version: 60 DIP protein Q15788-1 original sequence version: 62 DIP protein Q15788 original sequence version: 88 DIP protein Q15788 original sequence version: 107 DIP protein Q15788 original sequence version: 96 25EF6F389489121E asxl1-rara 7 15 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait physical association physical association no figure rara-asxl1 8 15 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait physical association physical association 2B and C, 3A and 4 rara-ncoa1 8 22 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait physical association physical association 2B and C, 3A asxl1-rara-2 8 21 unspecified role unspecified role bait bait 19 unspecified role unspecified role prey prey physical association physical association 2C rxra-asxl1 8 19 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association 2C rxra-asxl1-1 8 17 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey physical association physical association 2C, 3 C rxra-ncoa1 8 22 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association 2C, 3C esr1-ncoa1-3 8 18 unspecified role unspecified role bait bait 22 unspecified role unspecified role prey prey physical association physical association 2C esr1-asxl1 8 18 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey physical association physical association 2C esr1-asxl1-1 8 18 unspecified role unspecified role bait bait 19 unspecified role unspecified role prey prey physical association physical association 2C nr3c1-asxl1 8 12 unspecified role unspecified role bait bait 19 unspecified role unspecified role prey prey physical association physical association 2C nr3c1-asxl1-1 8 12 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey physical association physical association 2C nr3c1-ncoa1-2 8 12 unspecified role unspecified role bait bait 22 unspecified role unspecified role prey prey physical association physical association 2C thrb-ncoa1 8 22 unspecified role unspecified role prey prey 14 unspecified role unspecified role bait bait physical association physical association 2C thrb-asxl1 8 14 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey physical association physical association 2C thrb-asxl1-1 8 14 unspecified role unspecified role bait bait 19 unspecified role unspecified role prey prey physical association physical association 2C asxl1-rarb 1 15 unspecified role unspecified role bait bait 16 unspecified role unspecified role prey prey direct interaction direct interaction 5A asxl1-rxra 1 15 unspecified role unspecified role bait bait 17 unspecified role unspecified role prey prey direct interaction direct interaction 5A asxl1-thrb 1 14 unspecified role unspecified role prey prey 15 unspecified role unspecified role bait bait direct interaction direct interaction 5A asxl1-esr1 1 18 unspecified role unspecified role prey prey 15 unspecified role unspecified role bait bait direct interaction direct interaction 5A asxl1-rarb-1 4 19 unspecified role unspecified role prey prey 13 unspecified role unspecified role bait bait physical association physical association 5B rxra-asxl1-2 4 17 unspecified role unspecified role bait bait 19 unspecified role unspecified role prey prey physical association physical association 5B asxl1-rara-3 5 19 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait physical association physical association 5B rxra-asxl1-3 5 19 unspecified role unspecified role prey prey 20 unspecified role unspecified role bait bait physical association physical association 5B nr3c1-asxl1-2 5 12 unspecified role unspecified role bait bait 19 unspecified role unspecified role prey prey physical association physical association 5B asxl1-esr1-1 6 18 unspecified role unspecified role bait bait 19 unspecified role unspecified role prey prey physical association physical association 5B asxl1-rara-4 10 19 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait physical association physical association 5C asxl1-rara-5 3 19 unspecified role unspecified role neutral component neutral component 21 unspecified role unspecified role neutral component neutral component physical association physical association 5D asxl1-ncoa1 9 22 unspecified role unspecified role bait bait 19 unspecified role unspecified role prey prey physical association physical association 7C, D and E asxl1-ncoa1-1 2 22 unspecified role unspecified role prey prey 19 unspecified role unspecified role bait bait direct interaction direct interaction 7F rara-ncor1-1 8 11 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait physical association physical association 2B AtRA (All-trans Retinoic Acid) This is a Positive Control. As a control, the interaction between NcoR-1 and RAR was abrogated in the presence of AtRA.