MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I. Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I. J. Biol. Chem. (0021-9258) 1997 Auethavekiat V., Abrams CS., Majerus PW. suggested by apalma partial coverage rapid curation human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Auethavekiat V., Abrams CS., Majerus PW. suggested by apalma J. Biol. Chem. (0021-9258) 1997 partial coverage rapid curation Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I. Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I. J. Biol. Chem. (0021-9258) 1997 Auethavekiat V., Abrams CS., Majerus PW. suggested by apalma partial coverage rapid curation in vitro In vitro enzymatic study enzymatic study predetermined predetermined participant predetermined Auethavekiat V., Abrams CS., Majerus PW. suggested by apalma J. Biol. Chem. (0021-9258) 1997 partial coverage rapid curation Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I. Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I. J. Biol. Chem. (0021-9258) 1997 Auethavekiat V., Abrams CS., Majerus PW. suggested by apalma partial coverage rapid curation in vitro In vitro affinity chrom affinity chromatography technology Affinity purification Affinity purification affinity chrom predetermined predetermined participant predetermined Auethavekiat V., Abrams CS., Majerus PW. suggested by apalma J. Biol. Chem. (0021-9258) 1997 partial coverage rapid curation Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I. Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I. J. Biol. Chem. (0021-9258) 1997 Auethavekiat V., Abrams CS., Majerus PW. suggested by apalma partial coverage rapid curation in vitro In vitro anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Auethavekiat V., Abrams CS., Majerus PW. suggested by apalma J. Biol. Chem. (0021-9258) 1997 partial coverage rapid curation plek_human Pleckstrin PLEK P47 Platelet 47 kDa protein protein protein human Homo sapiens Human MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVFKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDTEKGIKELNLEKDKKIFNHCFTGNCVIDWLVSNQSVRNRQEGLMIASSLLNEGYLQPAGDMSKSAVDGTAENPFLDNPDAFYYFPDSGFFCEENSSDDDVILKEEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGAEDPLGAIHLRGCVVTSVESNSNGRKSEEENLFEIITADEVHYFLQAATPKERTEWIRAIQMASRTGK 2E292CB18B533261 i5p1_human Inositol polyphosphate-5-phosphatase A 43 kDa inositol polyphosphate 5-phosphatase 5PTASE Type I inositol 1,4,5-trisphosphate 5-phosphatase INPP5A protein protein human Homo sapiens Human MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPSVYSGIRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRKVMLQLEKKLFDYFNQEVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDARQGEQYMNTRCPAWCDRILMSPSAKELVLRSESEEKVVTYDHIGPNVCMGDHKPVFLAFRIMPGAGKPHAHVHKCCVVQ mint Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction F55C0DFDDA01A850 inpp5a-plek 3 6 unspecified role unspecified role bait bait 5 unspecified role unspecified role prey prey direct interaction direct interaction homomint mint fig.3 inpp5a-plek-1 1 6 unspecified role unspecified role bait bait 5 unspecified role unspecified role prey prey direct interaction direct interaction homomint mint fig.3 inpp5a-plek-2 4 6 unspecified role unspecified role neutral component neutral component 5 unspecified role unspecified role neutral component neutral component association association homomint mint fig.4 inpp5a-plek-3 2 6 enzyme enzyme neutral component neutral component 5 stimulator stimulator neutral component neutral component association association homomint mint fig.5