UniProt UniProt http://www.uniprot.org The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo. The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo. Mol. Cell. Biol. (0270-7306) 1994 imex curation Minami Y., Kimura Y., Kawasaki H., Suzuki K., Yahara I. yahara%rinshoken.orjp@gssm.otsuka. tsukuba.ac.jp 06-Jun-2011: Contacted by JYOTI. orchard Only protein-protein interactions in vitro In vitro crosslink cross-linking study crosslink autoradiography autoradiography Minami Y., Kimura Y., Kawasaki H., Suzuki K., Yahara I. Cross-linking agent 0.002% glutaraldehyde yahara%rinshoken.orjp@gssm.otsuka. tsukuba.ac.jp Accepted 2011-APR-28 by ORCHARD 06-Jun-2011: Contacted by JYOTI. Mol. Cell. Biol. (0270-7306) 1994 orchard Only protein-protein interactions imex curation The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo. The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo. Mol. Cell. Biol. (0270-7306) 1994 imex curation Minami Y., Kimura Y., Kawasaki H., Suzuki K., Yahara I. yahara%rinshoken.orjp@gssm.otsuka. tsukuba.ac.jp 06-Jun-2011: Contacted by JYOTI. orchard Only protein-protein interactions mouse-lymphoblast Mus musculus lymphoblast Transformed lymphocytes; Blast cell; Lymphoblastoid bn-page blue native page bn-page edman degradation edman degradation Minami Y., Kimura Y., Kawasaki H., Suzuki K., Yahara I. yahara%rinshoken.orjp@gssm.otsuka. tsukuba.ac.jp Accepted 2011-APR-28 by ORCHARD 06-Jun-2011: Contacted by JYOTI. Mol. Cell. Biol. (0270-7306) 1994 orchard Only protein-protein interactions imex curation The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo. The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo. Mol. Cell. Biol. (0270-7306) 1994 imex curation Minami Y., Kimura Y., Kawasaki H., Suzuki K., Yahara I. yahara%rinshoken.orjp@gssm.otsuka. tsukuba.ac.jp 06-Jun-2011: Contacted by JYOTI. orchard Only protein-protein interactions in vitro In vitro bn-page blue native page bn-page autoradiography autoradiography Minami Y., Kimura Y., Kawasaki H., Suzuki K., Yahara I. yahara%rinshoken.orjp@gssm.otsuka. tsukuba.ac.jp Accepted 2011-APR-28 by ORCHARD 06-Jun-2011: Contacted by JYOTI. Mol. Cell. Biol. (0270-7306) 1994 orchard Only protein-protein interactions imex curation hs90a_mouse Heat shock protein HSP 90-alpha Hsp90aa1 Hsp86 Hsp86-1 Hspca Heat shock 86 kDa Tumor-specific transplantation 86 kDa antigen protein protein mouse Mus musculus Mouse MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEEKEEEKEKEEKESDDKPEIEDVGSDEEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTSAAVTEEMPPLEGDDDTSRMEEVD DIP protein P07901 original sequence version: 141 D92B8FD38A463B4E hs90a_human Heat shock protein HSP 90-alpha HSP90AA1 HSP90A HSPC1 Heat shock 86 kDa Renal carcinoma antigen NY-REN-38 HSPCA Lipopolysaccharide-associated protein 2 protein protein human Homo sapiens Human MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD DIP protein P07900 original sequence version: 197 DIP protein P07900 original sequence version: 116 DIP protein P07900 original sequence version: 150 DIP protein P07900-1 original sequence version: 158 DIP protein P07900 original sequence version: 207 DIP protein P07900 original sequence version: 192 DIP protein P07900 original sequence version: 156 969F65FCC0BC86FD hsp90aa1-hsp90aa1-3 2 4 unspecified role unspecified role neutral component neutral component physical association physical association fig1 and table 1 hsp90aa1-4 3 5 unspecified role unspecified role neutral component neutral component region sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined in vitro In vitro physical association physical association Fig. 2 hsp90aa1-4 1 5 unspecified role unspecified role neutral component neutral component region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 2