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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>MINT</shortLabel>
        <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
        <alias type="synonym" typeAc="MI:1041">MINT</alias>
      </names>
      <bibref>
        <xref>
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      </bibref>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0471" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="mint" dbAc="MI:0471" id="MINT-80017" refType="identity" refTypeAc="MI:0356"/>
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        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
        <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
        <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
        <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
        <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Crystal structure of an ascomycete fungal laccase from Thielavia arenaria--common structural features of asco-laccases.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="21535408" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="mint" dbAc="MI:0471" id="MINT-8170699" refType="primary-reference" refTypeAc="MI:0358"/>
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            <secondaryRef db="mint" dbAc="MI:0471" id="fj-11-0200" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8662546" refType="identity" refTypeAc="MI:0356"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Crystal structure of an ascomycete fungal laccase from Thielavia arenaria--common structural features of asco-laccases.</attribute>
            <attribute name="journal" nameAc="MI:0885">FEBS J. (1742-464X)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2011</attribute>
            <attribute name="author-list" nameAc="MI:0636">Kallio JP., Gasparetti C., Andberg M., Boer H., Koivula A., Kruus K., Rouvinen J., Hakulinen N.</attribute>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-8170708" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="fj-11-0200" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="pubmed" dbAc="MI:0446" id="21535408" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Kallio JP., Gasparetti C., Andberg M., Boer H., Koivula A., Kruus K., Rouvinen J., Hakulinen N.</attribute>
          <attribute name="journal" nameAc="MI:0885">FEBS J. (1742-464X)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2011</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>f6n9e7_9pezi</shortLabel>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="F6N9E7" version="TrEMBL_12" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9844077" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033138"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001117"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011706"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011707"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002355"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008972"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="F6N9E7"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005507" version="TrEMBL_46"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0052716" version="TrEMBL_46"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PPS" version="TrEMBL_46"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="2609790">
          <names>
            <shortLabel>9pezi</shortLabel>
            <fullName>Canariomyces arenarius</fullName>
          </names>
        </organism>
        <sequence>MKSWAAAVALMVGILSPHAAAAPPANPVQRDMLQVLEARQSGPTCNTPSNRACWTNGFDINTDYEVSTPNTGRTVAYQLTLTEKENWIGPDGVLKNVVMLVNDKIIGPTIRANWGDNIEVTVINNLKTNGTSMHWHGLRQLGNVFNDGANGVTECPIPPKGGRKTYKFRATQYGTSWYHSHFSAQYGNGVVGTIQIDGPASLPYDIDLGVFPLMDYYYRSADELVHFTQSNGAPPSDNVLFNGTARHPETGAGQWYNVTLTPGKRHRLRIINTSTDNHFQVSLVGHNMTVIATDMVPVNAFTVSSLFLAVGQRYDVTIDANSPVGNYWFNVTFGDGLCGSSNNKFPAAIFRYQGAPATLPTDQGLPVPNHMCLDNLNLTPVVTRSAPVNNFVKRPSNTLGVTLDIGGTPLFVWKVNGSAINVDWGKPILDYVMSGNTSYPVSDNIVQVDAVDQWTYWLIENDPTNPIVSLPHPMHLHGHDFLVLGRSPDELPSAGVRHIFDPAKDLPRLKGNNPVRRDVTMLPAGGWLLLAFKTDNPGAWLFHCHIAWHVSGGLSVDFLERPNDLRTQLNSNAKRADRDDFNRVCREWNAYWPTNPFPKIDSGL</sequence>
        <attributeList>
          <attribute name="crc64">84A810556D762F5D</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="3">
        <names>
          <shortLabel>ta lcc1</shortLabel>
        </names>
        <xref>
          <primaryRef db="wwpdb" dbAc="MI:0805" id="3pps" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="MINT-8173385" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8662559" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="4">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">laccase</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-8173391" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>2</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <stoichiometry value="4"/>
            <attributeList>
              <attribute name="comment" nameAc="MI:0612">Stoichiometry: 4.0</attribute>
            </attributeList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="3d-r-factors" nameAc="MI:0631">Rworking = 0.18 Rfree = 0.22</attribute>
          <attribute name="3d-resolution" nameAc="MI:0632">2.5 A</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>