IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS ONE (null) 2011 imex curation Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu 21-Dec-2011: Contacted by JYOTI. Only protein-protein interactions ecoli Escherichia coli (strain K12) solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu Accepted 2011-NOV-01 by MGT 21-Dec-2011: Contacted by JYOTI. PLoS ONE (null) 2011 Only protein-protein interactions imex curation Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS ONE (null) 2011 imex curation Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu 21-Dec-2011: Contacted by JYOTI. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu Accepted 2011-NOV-01 by MGT 21-Dec-2011: Contacted by JYOTI. PLoS ONE (null) 2011 Only protein-protein interactions imex curation Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS ONE (null) 2011 imex curation Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu 21-Dec-2011: Contacted by JYOTI. Only protein-protein interactions schpm Schizosaccharomyces pombe (fission yeast) Fission yeast tap tandem affinity purification TAP TAP tap sequence tag sequence tag identification sequence tag Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. Spectra with less than 6 peaks were excluded from the analysis. The S. pombe database (http://www.sanger.ac.uk) was searched using the SEQUEST algorithm, and results were processed using the CHIPS program (jointly developed by Vanderbilt University Mass Spectrometry Research Center and University of Arizona). Filter settings for peptides were: Xcorr≥1.8 for singly charged; Xcorr≥2.5 for doubly charged; Xcorr≥3.3 for triply charged. kathy.gould@vanderbilt.edu Accepted 2011-NOV-01 by MGT 21-Dec-2011: Contacted by JYOTI. PLoS ONE (null) 2011 Only protein-protein interactions imex curation Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS ONE (null) 2011 imex curation Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu 21-Dec-2011: Contacted by JYOTI. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu Accepted 2011-NOV-01 by MGT PLoS ONE (null) 2011 Only protein-protein interactions imex curation Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS ONE (null) 2011 imex curation Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu 21-Dec-2011: Contacted by JYOTI. Only protein-protein interactions in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu Accepted 2011-NOV-01 by MGT 21-Dec-2011: Contacted by JYOTI. PLoS ONE (null) 2011 Only protein-protein interactions imex curation Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS ONE (null) 2011 imex curation Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu 21-Dec-2011: Contacted by JYOTI. Only protein-protein interactions in vitro In vitro solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu Accepted 2011-NOV-01 by MGT 21-Dec-2011: Contacted by JYOTI. PLoS ONE (null) 2011 Only protein-protein interactions imex curation Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS ONE (null) 2011 imex curation Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu 21-Dec-2011: Contacted by JYOTI. Only protein-protein interactions yeast Saccharomyces cerevisiae Baker's yeast tap tandem affinity purification TAP TAP tap sequence tag sequence tag identification sequence tag Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. Spectra with less than 6 peaks were excluded from the analysis. The S. pombe database (http://www.sanger.ac.uk) was searched using the SEQUEST algorithm, and results were processed using the CHIPS program (jointly developed by Vanderbilt University Mass Spectrometry Research Center and University of Arizona). Filter settings for peptides were: Xcorr≥1.8 for singly charged; Xcorr≥2.5 for doubly charged; Xcorr≥3.3 for triply charged. kathy.gould@vanderbilt.edu Accepted 2011-NOV-01 by MGT 21-Dec-2011: Contacted by JYOTI. PLoS ONE (null) 2011 Only protein-protein interactions imex curation Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS ONE (null) 2011 imex curation Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu 21-Dec-2011: Contacted by JYOTI. Only protein-protein interactions schpm Schizosaccharomyces pombe (fission yeast) Fission yeast anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu Accepted 2011-NOV-01 by MGT 21-Dec-2011: Contacted by JYOTI. PLoS ONE (null) 2011 Only protein-protein interactions imex curation Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS ONE (null) 2011 imex curation Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu 21-Dec-2011: Contacted by JYOTI. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. I could not open Supp. Fig. 2A but prp17 domain is given in the text so can only hope the figure shows the same. kathy.gould@vanderbilt.edu Accepted 2011-NOV-01 by MGT 21-Dec-2011: Contacted by JYOTI. PLoS ONE (null) 2011 Only protein-protein interactions imex curation Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS ONE (null) 2011 imex curation Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu 21-Dec-2011: Contacted by JYOTI. Only protein-protein interactions yeast Saccharomyces cerevisiae Baker's yeast anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. kathy.gould@vanderbilt.edu Accepted 2011-NOV-01 by MGT 21-Dec-2011: Contacted by JYOTI. PLoS ONE (null) 2011 Only protein-protein interactions imex curation brr2_schpo Pre-mRNA-splicing factor brr2 Pre-mRNA-splicing factor spp41 brr2 SPAC9.03c Pre-mRNA-splicing helicase BRR2 spp41 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSSAHPKGDSKEPPKHGNSKEKPNYGQSQYSYSAMSNLVTQADRRFVSRRDAEPTGEPESLVNRVSIADMGSRARIEKPSTLPLELTQEVQEVRLPRKDAESLEIGIRQPEREKRSSAILKYFDSFEILKYNPLTDETREVYDYILSFIQQYLGDQSPEILRSAADLIIELLKDSSLDEQGRKKQIEEVLSTELPQDRFSQLVNLGNRLTDYTVEQEEELNEEGVNESGVPVLFNEADEEEEAVEAMEEDEVAEDEDVVLETSISQEEEKKNIENPDTEVTFISADTKKVTEIPTVHPREIDAFWLQREIAKYFADAVVCQEKTNQAFEALSADYDLGELENELMSIFDYEHFYLVQLLTKNRWTIVSCTMLKRAATDEERLGVEEQIRAAGRSWILEALRPGAITIPDDGLNELNNNVVEKAEPAPVSEIPLSKTLTSHKIVPKHQVDLENYVFTEGSRLMSNKAVKLPEGSFRRTGKGYEEIHVPAPNKAVLGADERLVKIKELPEWSHQAFLNTQSLNRIQSHLYPIAFGTDENILLCAPTGAGKTNVAMLCILNELQKHLREDLSFNLQNFKIVYIAPLKALVQEMVNNFSKRLTPYNIRVAELTGDSQLTKQQISETQIIVTTPEKWDIITRKANDLSYVNLVRLVIIDEVHLLHDERGPVLESIVARIFRHQEETLEQVRLVGLSATLPNYTDVASFLHVDPKKGLFYFDSTYRPCPLKQEFIGITEKTPFKRMQTTNEACYEKVMQHAGKNQVLIFVHSRKETAKTARFIRDKALEEETIGHLLRSDAASREILRAEADSTSDENLKDLLPYGFAIHHAGMRREDRQTSEDLFADGTIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGIWTELSPQDVLQMLGRAGRPQFDTYGEGIIITAHSELQYYLSLMNQQLPIESQFMRRLADCLNAEVSLGTVRSIEDGVDWLGYTYLYVRMLRSPALYSVGPEYDDDKYLVQKRADLLHSAAILLEKCKLLVYNRQSGTLTATELGKVAASYYVTHNSMAIYNRLLMQTTSFIELFRVFSFSDEFKHIPVREEEKVELAKLLERVPIPIRERLDEPAAKINALLQSYISRQRLDGFALVADMVYVTQSAGRIMRAIFEISLRRGWSSVATLSLDTCKMIEKRLWPTMSPLRQFPNCPSEVIRRVEKKEFPWQRYFDLDPAELGELVGVPKEGRRVYNMVQSFPRLSVEAHVQPITRSLVRVELVINSQFNWDDHLSGTSEAFWILVEDVDGDRLLHYEQFFLLKKYKDDEHIVNFTVPLLEPLPPCYFIKIVSDRWLHSITKVPLSFQRLIMPEKFPAPTPLLDLQNAPVSSLNNPSFISLYPNFKFFNKIQTQVFNSVYKTNDSVFIGAPNGSGKTVCAELALLHHWSQEDYGTAVYIAPIQEIVDRRYEEWYGKFSDLGDGKVLVKLTGERSQDLKLIQVADLIFCTPSQWDSLSKRWRSMRSIQKVDFYICDELQLLGGFYGPLYEIVISRIRYMAVQLEKNIRVVGLSVSVANARDLGEWLGTSPQCIFNFSPKDRPNPLTIHLQSFSITHFPSLMLAMSKPIYRSLKNFISQRKSTIVFTPDRKVAKQLAFDLVTFSMADEDEYLFSLMENEAFNKVEDAALQQSLKHGIAYISEITSSNDQNIVQYLYRHGLIKVLIASRDVIYSLKAKSNAVIVMGTQYYDGKEHRYIDYPISELLQMLGFTASIGSSELSQVILMTVTTKKEYYKKFLNEPLPMESHLQVWLHDAFVSEISTQTIESKQDAVDWLTWSYMYRRLVANPAYYGLQDITHESVSEFLSDLVETTMNDLSEARLITVDDEDDSCVALNLAMIASHYGITYITMQTFALSLSERTKMKGLLEIVTSAAEYEQLPIRKYEDIVLERIHSRLPVRLSNPNYEDPHTKSFILLAAHFSRFELPPGLVIDQKFILTRVHNLLGACVDTLSSEGHLIACIRPMEMSQMVTQALWDRDSPLKQIPYFDDALIERCNKEGVHDVFDIIDLDDEKRTELLHMDNAHLAKCAEFINKYPDIDIDFEIEDSEDVHANSPSVLIVQLTRELEEDEEVDTTVIAPYFPAQKTEHWWLVISDDKTLLAIKKITLGRSLTTKMEFVPPAMGTLKYKLSCFSDSYMGVDYEKEFECNVLEPLDTEMEDGE 369A1FA6EA8951AA snu66_schpo U4/U6.U5 tri-snRNP-associated protein snu66 snu66 SPAC167.03c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSGNSGASESISIEETNRIRISLGLKPLDISEEKPQKELSDASVKSSYVDQEQQAYENWKKQEQEEINRKKEEELKSKFEKLRQKNERRRRTQGKTLAETLAEEDDQIDANDTRAWILKMRNSSLNKNGNGLNFEAKNDAPRRSTLHSQNAGPNVNSSLEGMKIAHGFQDLNKNDGLVLTLKDADILDEDNHDLLENVEMVQRKTKNERKEDNPYKPYEDENDFLQQSEADQPSEDTFTTIGPQNSLTVNSTIEKHKSDNKKTFGTLVSFVEPTITGSEQSDYRQIKIKKSKKKKSKSDRRKRLVELDAENENENDPSDFVLPNGQSNSDLSVEQDSAIFKEQKKMKIQKRMRELETQSFADDDDLQQSIAMQRRLAQKRAKILKPEDVAEQLQNAEEVTDMTDSDTASGLIFDDTRAFVNSIKETENREALGSINEQAFEDSKDLNDTNSITGSSPTEESNALVEDTSVDISATLEEANTQQENAEDEPLVSDNVGAVLSLLRNKGVIKVSDEAKEKIQKEEEYNKWFARKQQARVELEEQRRKKKEQDRLSGKFEKMTQKEREQYAKKENERWDKKIAEIELEQFHDYKPQVDIKYVDEFGVELGPKEAYKYLLSHQFHGKGSGKAKTEKRLRRIVEKEREERKPIF 27EC1138F612329D sn114_schpo Pre-mRNA-splicing factor cwf10 cwf10 snu114 spef2 SPBC215.12 Complexed with cdc5 protein 10 114 kDa U5 small nuclear ribonucleoprotein component homolog protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MMEEDLYDEFGNYIGPENEEDEEELFPQAPSPTIAQVPSFEEVIPDEELEDVERAEEMALSHLEPQNAVVLHEDKQYYPSAEEVYGSNVDIMVQEQDTQPLSQPIIEPIRHKRIAIETTNVPDTVYKKEFLFGLLTGTDDVRSFIVAGHLHHGKSALLDLLVYYTHPDTKPPKRRSLRYTDTHYLERERVMSIKSTPLTLAVSDMKGKTFAFQCIDTPGHVDFVDEVAAPMAISDGVVLVVDVIEGVMINTTRIIKHAILHDMPIVLVLNKVDRLILELRLPPNDAYHKLRHVIDEVNDNICQISKDLKYRVSPELGNVCFASCDLGYCFTLSSFAKLYIDRHGGIDVDLFSKRLWGDIYFDSKTRKFAKQSLDGSGVRSFVHFILEPLYKLHTLTISDEAEKLKKHLSSFQIYLKPKDYLLDPKPLLQLICASFFGFPVGFVNAVTRHIPSPRENAARKASQSYIGPINSSIGKAILEMSREESAPLVMHVTKLYNTVDANNFYAFARVYSGQVKKGQKVKVLGENYSLEDEEDMVVAHIAEICVPCARYRLHVDGAVAGMLVLLGGVDNSISKTATIVSDNLKDDPYIFRPIAHMSESVFKVAVEPHNPSELPKLLDGLRKTNKSYPLSITKVEESGEHTIFGTGEMYMDCLLYDLRTLYSEIEIRVSDPVARFCETAVDTSSIKCFSDTPNKKNRITMVVEPLEKGISNDIENGKVNINWPQKRISEFFQKNYDWDLLASRSIWAFGPDDRGTNILRDDTLSTDVDKNVLNSVKEYIKQGFQWGTREGPLCDETIRNVNFRLMDVVLAPEQIYRGGGQIIPTARRVCYSSFLTASPRLMEPVYMVEVHAPADSLPIIYDLLTRRRGHVLQDIPRPGSPLYLVRALIPVIDSCGFETDLRVHTQGQAMCQMVFDHWQVVPGDPLDKSIKPKPLEPARGSDLARDFLIKTRRRKGLVEDVSTTRYFDQEMIDSLKEAGVVLSL B15A139BEC1EA53E mpip_yeast M-phase inducer phosphatase MIH1 YMR036C YM9532.01C YM9973.10C Mitosis initiation protein MIH1 Mitotic inducer homolog protein protein yeast Saccharomyces cerevisiae Baker's yeast MNNIFHGTEDECANEDVLSFQKISLKSPFGKKKNIFRNVQTFFKSKSKHSNVDDDLINKENLAFDKSPLLTNHRSKEIDGPSPNIKQLGHRDELDENENENDDIVLSMHFASQTLQSPTRNSSRRSLTNNRDNDLLSRIKYPGSPQRSSSFSRSRSLSRKPSMNSSSNSSRRVQRQDGKIPRSSRKSSQKFSNITQNTLNFTSASSSPLAPNSVGVKCFESCLAKTQIPYYYDDRNSNDFFPRISPETLKNILQNNMCESFYNSCRIIDCRFEYEYTGGHIINSVNIHSRDELEYEFIHKVLHSDTSNNNTLPTLLIIHCEFSSHRGPSLASHLRNCDRIINQDHYPKLFYPDILILDGGYKAVFDNFPELCYPRQYVGMNSQENLLNCEQEMDKFRRESKRFATKNNSFRKLASPSNPNFFYRDSHQSSTTMASSALSFRFEPPPKLSLNHRRVSSGSSLNSSESTGDENFFPILSKSSMSSNSNLSTSHMLLMDGLDTPSYFSFEDERGNHQQVSGDEEQDGDFTFVGSDREDLPRPARRSLFPSLETEDKK DBD85D02CF48CA6F DBD85D02CF48CA6F ru2a_yeast U2 small nuclear ribonucleoprotein A' YPL213W LEA1 Looks exceptionally like U2A protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MKFTPSIVIDAPQYYVDHFNGKYNVDKCVILRDLQLETDSESMPSSLKHLTKPTHILDLTNNDLIMIPDLSRRDDIHTLLLGRNNIVEVDGRLLPMNVQNLTLSNNSIRRFEDLQRLRRAPRTLKNLTLIGNQVCHLANYREHVLRLVPHLETLDFQNVTAEERKSAMSFPRQADGDTLGPVNTAIRDNGSRDKTMEIMNLVVSKMTVERRNELKKQLAEATSLEEIARLEKLLSGGV 0E92A1922BFEDC25 ruxg_schpo Small nuclear ribonucleoprotein G SPBC4B4.05 smg1 Sm protein G protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSKAGAPDLKKYLDRQVFVQLNGSRKVYGVLRGYDIFLNIVLEDSIEEKVDGEKVKIGSVAIRGNSVIMIETLDKMT 6468E36CFEA8139A erg8_schpo Probable phosphomevalonate kinase erg8 SPAC343.01c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MKVTCSAPGKVLIAGGYIVLDPQYSGLVIGLTAKGYASTTTLDDKCGTVRVKSPQFINAEWLYNIDWTVSPIRVHQIYENCELEKNPNPFVQLALFYVINYFFSTGRQPLCWQDLQVTLQVDNAYYHQPQLKPDQTSYPKFNFLNCTLGQVHKTGLGSSAAMITSLIGSLFLSLRRLTDDTGDKSLKIDDSTKVIVHNLAQIAHCSAQGKVGSGFDVGAATWGSCIYRRFDPKLIEQLLVPYDEQIKNINFSTELRKIVSKKWSDVVPFQLPATYCLLMGDVAGGSSTPGMVKKVQQWQKENPEESKNCFDDLYSRVLSIKNCFLSSESLDSELQSQFRSIRRILQRITVEAKVDIEPLKQTNILDNIEQLPGVIGVGVPGAGGFDAQFCLAINHTEIIENVIKTWKDDGVVPMDVSPAFDGLAVE 25635B99E7FAAD64 clf1_yeast Pre-mRNA-splicing factor CLF1 CLF1 NTC77 YLR117C SYF3 L2952 Crooked neck-like factor 1 PRP19-associated complex protein 77 Synthetic lethal with CDC40 protein 3 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDTLEPTAVDTHVSAEQILRDVYKKGQKARGSTNIDILDLEELREYQRRKRTEYEGYLKRNRLDMGQWIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLWIRYIDAELKVKCINHARNLMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWCSLEPGVNAWNSFVDFEIRQKNWNGVREIYSKYVMAHPQMQTWLKWVRFENRHGNTEFTRSVYSLAIDTVANLQNLQIWSDMEVAKLVNSFAHWEAAQQEYERSSALYQIAIEKWPSNQLLKAGLLDFEKQFGDINSIEETISYKRKMEYETILSNNAYDYDTWWLYLDLISESFPKQIMQTFEKAIVDSRPKELSKNVQWKRYIYLWMRYICYVELELENSLLEEELFQRLIDDIIPHKHFTFSKIWLMYAKFLIRHDDVPKARKILGKAIGLCPKAKTFKGYIELEVKLKEFDRVRKIYEKFIEFQPSDLQIWSQYGELEENLGDWDRVRGIYTIALDENSDFLTKEAKIVLLQKYITFETESQEFEKARKLYRRYLELNQYSPQSWIEFAMYQTSTPTEQQLLDLAKLQSENVDEDIEFEITDENKLEARKVFEEAIVFFKEKDDKQGRLSILEALKDYEETYGTELDQETVKKRFPKVIKKVRLQNGVEEEFVDYIFPDDIDDDKPKPSKFLELAKKWKQEQAL AE7D5EC5B3979E00 AE7D5EC5B3979E00 cef1_yeast Pre-mRNA-splicing factor CEF1 CEF1 YMR213W YM8261.07 NTC85 PRP nineteen-associated complex protein 85 PRP19-associated complex protein 85 protein protein yeast Saccharomyces cerevisiae Baker's yeast MPPVPIYVKGGVWTNVEDQILKAAVQKYGTHQWSKVASLLQKKTARQSELRWNEYLNPKLNFTEFSKEEDAQLLDLARELPNQWRTIADMMARPAQVCVERYNRLLESEDSGGAALSTGVTDLKAGDINPNAETQMARPDNGDLEDEEKEMLAEARARLLNTQGKKATRKIRERMLEESKRIAELQKRRELKQAGINVAIKKPKKKYGTDIDYNEDIVYEQAPMPGIYDTSTEDRQIKKKFEQFERKVNRKGLDGNKDKPSKKNKDKKRKHDENEHVEKAALGESTTLTDEYKKPKLILSAPGTKQGKVTYKKKLESKRQKLIEAQATGTVLTPKELLPHDSGQEDNERSNIKSGKQLKSRIRKFLVQMFASLPSPKNDFEIVLSEDEKEEDAEIAEYEKEFENERAMNEEDNFIEPPSQNDAPRVSLVAVPLAYSTLPIPEFKNNPQSAIDNKYNLLVANAINKEPHMVPEDTVDFLKEVESRMQHITQGRTSMKIQFKTAMPPTEVLLESIQSKVESIEQLQRKLQHVQPLEQQNNEMCSTLCHHSLPALIEGQRKYYADYYAYRQEIRSLEGRRKRLQAMLNSSSSI A4C417A8B330EA9C A4C417A8B330EA9C ist3_schpo U2 snRNP component ist3 ist3 RNA-binding protein cwf29 Complexed with cdc5 protein 29 cwf29 SPBC887.05c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MNSIRQIERLNEQELDKPFSSSWHQDYSDSAYIYIGNLDFDLNEDDILCVFSEFGEPVDINLVRDKETGKSKGFAFLKYEDQRSTVLAVDNMTNVKLLDRLVRVDHVASYKVPQKEKEPANLVPLGESGSSLSVSTINTSNLPDHDYKTIIQNEVEQTLSPKDEKDLLDPMRDYIHREKRRKLKHESSDRSDKSDSNRHSRHHRRHSRSRRHRDLDG 4F42BFA4ABAA0C8F ruxe_schpo Small nuclear ribonucleoprotein E sme1 Sm protein E SPBC11G11.06c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSGRVQKVMIPPINFIFKLLQQHTPVSIWLFEQTDIRLQGQIRGFDEFMNIVLDDAVQVDAKNNKRELGRILLKGDNITLIQAI F74655EA6D48793D uba3_yeast NEDD8-activating enzyme E1 catalytic subunit Ubiquitin-activating enzyme E1 3 RUB1-activating enzyme E1 Ubiquitin-like protein-activating enzyme UBA3 YPR066W YP9499.21 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDCKILVLGAGGLGCEILKNLTMLSFVKQVHIVDIDTIELTNLNRQFLFCDKDIGKPKAQVAAQYVNTRFPQLEVVAHVQDLTTLPPSFYKDFQFIISGLDAIEPRRFINETLVKLTLESNYEICIPFIDGGTEGLKGHVKTIIPGITACWECSIDTLPSQQDTVPMCTIANNPRCIEHVVEYVSTIQYPDLNIESTADMEFLLEKCCERAAQFSISTEKLSTSFILGIIKSIIPSVSTTNAMVAATCCTQMVKIYNDLIDLENGNNFTLINCSEGCFMYSFKFERLPDCTVCSNSNSN 2C355EF52AB8092F brr2_yeast Pre-mRNA-splicing helicase BRR2 BRR2 RSS1 SNU246 YER172C SYGP-ORF66 Protein Snu246 protein protein yeast Saccharomyces cerevisiae Baker's yeast MTEHETKDKAKKIREIYRYDEMSNKVLKVDKRFMNTSQNPQRDAEISQPKSMSGRISAKDMGQGLCNNINKGLKENDVAVEKTGKSASLKKIQQHNTILNSSSDFRLHYYPKDPSNVETYEQILQWVTEVLGNDIPHDLIIGTADIFIRQLKENEENEDGNIEERKEKIQHELGINIDSLKFNELVKLMKNITDYETHPDNSNKQAVAILADDEKSDEEEVTEMSNNANVLGGEINDNEDDDEEYDYNDVEVNSKKKNKRALPNIENDIIKLSDSKTSNIESVPIYSIDEFFLQRKLRSELGYKDTSVIQDLSEKILNDIETLEHNPVALEQKLVDLLKFENISLAEFILKNRSTIFWGIRLAKSTENEIPNLIEKMVAKGLNDLVEQYKFRETTHSKRELDSGDDQPQSSEAKRTKFSNPAIPPVIDLEKIKFDESSKLMTVTKVSLPEGSFKRVKPQYDEIHIPAPSKPVIDYELKEITSLPDWCQEAFPSSETTSLNPIQSKVFHAAFEGDSNMLICAPTGSGKTNIALLTVLKALSHHYNPKTKKLNLSAFKIVYIAPLKALVQEQVREFQRRLAFLGIKVAELTGDSRLSRKQIDETQVLVSTPEKWDITTRNSNNLAIVELVRLLIIDEIHLLHDDRGPVLESIVARTFWASKYGQEYPRIIGLSATLPNYEDVGRFLRVPKEGLFYFDSSFRPCPLSQQFCGIKERNSLKKLKAMNDACYEKVLESINEGNQIIVFVHSRKETSRTATWLKNKFAEENITHKLTKNDAGSKQILKTEAANVLDPSLRKLIESGIGTHHAGLTRSDRSLSEDLFADGLLQVLVCTATLAWGVNLPAHTVIIKGTDVYSPEKGSWEQLSPQDVLQMLGRAGRPRYDTFGEGIIITDQSNVQYYLSVLNQQLPIESQFVSKLVDNLNAEVVAGNIKCRNDAVNWLAYTYLYVRMLASPMLYKVPDISSDGQLKKFRESLVHSALCILKEQELVLYDAENDVIEATDLGNIASSFYINHASMDVYNRELDEHTTQIDLFRIFSMSEEFKYVSVRYEEKRELKQLLEKAPIPIREDIDDPLAKVNVLLQSYFSQLKFEGFALNSDIVFIHQNAGRLLRAMFEICLKRGWGHPTRMLLNLCKSATTKMWPTNCPLRQFKTCPVEVIKRLEASTVPWGDYLQLETPAEVGRAIRSEKYGKQVYDLLKRFPKMSVTCNAQPITRSVMRFNIEIIADWIWDMNVHGSLEPFLLMLEDTDGDSILYYDVLFITPDIVGHEFTLSFTYELKQHNQNNLPPNFFLTLISENWWHSEFEIPVSFNGFKLPKKFPPPTPLLENISISTSELGNDDFSEVFEFKTFNKIQSQVFESLYNSNDSVFVGSGKGTGKTAMAELALLNHWRQNKGRAVYINPSGEKIDFLLSDWNKRFSHLAGGKIINKLGNDPSLNLKLLAKSHVLLATPVQFELLSRRWRQRKNIQSLELMIYDDAHEISQGVYGAVYETLISRMIFIATQLEKKIRFVCLSNCLANARDFGEWAGMTKSNIYNFSPSERIEPLEINIQSFKDVEHISFNFSMLQMAFEASAAAAGNRNSSSVFLPSRKDCMEVASAFMKFSKAIEWDMLNVEEEQIVPYIEKLTDGHLRAPLKHGVGILYKGMASNDERIVKRLYEYGAVSVLLISKDCSAFACKTDEVIILGTNLYDGAEHKYMPYTINELLEMVGLASGNDSMAGKVLILTSHNMKAYYKKFLIEPLPTESYLQYIIHDTLNNEIANSIIQSKQDCVDWFTYSYFYRRIHVNPSYYGVRDTSPHGISVFLSNLVETCLNDLVESSFIEIDDTEAEVTAEVNGGDDEATEIISTLSNGLIASHYGVSFFTIQSFVSSLSNTSTLKNMLYVLSTAVEFESVPLRKGDRALLVKLSKRLPLRFPEHTSSGSVSFKVFLLLQAYFSRLELPVDFQNDLKDILEKVVPLINVVVDILSANGYLNATTAMDLAQMLIQGVWDVDNPLRQIPHFNNKILEKCKEINVETVYDIMALEDEERDEILTLTDSQLAQVAAFVNNYPNVELTYSLNNSDSLISGVKQKITIQLTRDVEPENLQVTSEKYPFDKLESWWLVLGEVSKKELYAIKKVTLNKETQQYELEFDTPTSGKHNLTIWCVCDSYLDADKELSFEINVK DFAF7E3B7168D944 DFAF7E3B7168D944 cwc22_schpo Pre-mRNA-splicing factor cwf22 Complexed with cdc5 protein 22 cwf22 SPBC13E7.01 SPBC15D4.16 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MEKEDKSFGIGMLDYNRENPESSGHSRVAVIRKQKTEQENNNLSWEDRHYIPDLHKSNKIKTPTSLADEKKSHNELDPKAQIKKLMETRSGGTYIPPAKLKALQAQLTDVNTPEYQRMQWEALKKSINGLINKVNKSNIRDIIPELFQENIIRGRALYCRSIMKAQAASLPFTPIYAAMTAVINTKFPQIGELLLTRLIVQFRKSFQRNDKSMCISSSSFIAHLINQKIAHEIVGLQILAVLLERPTNDSIEIAVMLLREIGAYLAEVSTRAYNGVFERFRTILHEGQLERRTQFIIEVLFQTRKDKFKNNPTIPQELDLVEEEDQITHYISLDDNLDVQESLGIFHYDPDYEENEKKYDAIKHEILGEEDDDENEEDEEDSEETSESEEDESVNDEKPQVIDQTNASLVNLRKSIYLTIMSSVDFEECCHKLLKIDLPEGQEIELCNMVIECNSQERTYAKFYGLIGERFCKLSRTWRSTYEQCFKNYYETIHRYETNRLRNIALFFANLLSTDSIGWEVYDCVRLTEDDTTASSRIFLKIMFQEIVEALGLKSLVERLHDPNLVPYLHGLFPVDEARNVRFSINYFTSIGLGALTEEMREYLLTMPKSEPKEQDSEGYSSGSETGSTYSSSYSSTYSRGRSYSRSTRSYSKSRSYSRSRSVTPINNINHKKYIRKDRELSPRGRERSSNRNSYSDLSRSSSLSRGRSRSYTPEGRLIESEDKGYRSRSSSPASRKYRSRQRYRRSYAGSTSRGRSFSRSPSYRRRLSMSCSVSYSRSPSPAARPISRSPARNKRSYDSLSYNRQYSPKVSRKRSNESRSPSPYTLRKQKTYHLNKRNEDFVVKMDKKGSESPVILAPWLREVDDGELYKDRNSESDSVRKQPRAD D6681A6F09ADFF85 cwf17_schpo Pre-mRNA-splicing factor cwf17 cwf17 Complexed with cdc5 protein 17 SPBC1289.11 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MDKRKESESATNGHLVKRIRIQDSSLITEGSVLQRTSDLNVPNLQMFGHTAEVLVARFDPSGSYFASGGMDRQILLWNVFGDVKNYGVLNGCKGAITDLQWSRDSRVVYCSSSDTHLMSWDAVSGQKIRKHKGHAGVVNALDVLKVGSELLTSVSDDCTMKVWDSRSKDCIKTIEEKYPLTAVAIAQQGTQVFIGGIDGAIKIWDLRNNHCSHVLKGHKDIITSLAISKDGSSLLSNSMDNTVRIFDVKPFASAQRQLQIFEGAIHGQEHNLLGVAWSRNSRFVGAGSSDKNVYVWSATGDLRYVLPGHEGSVNHVDFHPHQDIILSCSSDRTIFLGELN BBAA5938CA4C24C2 spf27_schpo Pre-mRNA-splicing factor cwf7 Complexed with cdc5 protein 7 cwf7 spf27 SPBC28F2.04c Splicing factor 27 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSYNISLDSLPYFESTYNEEDRSAAAQIVEEELKRSGGLLIKQEEQKKKFQSHRLSDRLENAIVAAGKGEKLAAIDVQRYIQLKPPGTRESLLQSAVVWEYQKSRNDNLYLLEKHGEKAFDSSLEALEVQLELLEKELVNTKKLSQGCNRKRKHYQMEVGARLAEAEVKFGQLLQSSIQCRVATLLS C2CE833F1036FA33 sa114_schpo Pre-mRNA-splicing factor sap114 sap114 Spliceosome-associated protein 145 SPAC22A12.09c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSSLMEFQDRNTTNNETEHQKSITDQSSSVPAGVILPPPAIREIIDKSASYVARNGPAFEEKIRQNEQANTKFAFLHANDPYHPYYQHKLTEAREGKLKSHATGLSTQKTSTLARPIQKPIEATIPAPSPYLFSEPLPSISSLDLDVLRLTARYAAVRGSSFLVSLSQKEWNNTQFDFLKPNNALYPYFMRIVQQYTSLIREPISSPEQELRENVRDPYSLLSKIQPRVRWQSHMESQKKKQKEEAEKEKLEYAQIDWNDFVVVEVIQFTKSDEHAKLAKPTNLADLQTATLEQKSAMFTMPDQNYTIEEAPPTAEPWEPISAPKKQEFGVSLPPSLASPEKGGISSTTSVSPAAQASPVLSTTTQPKVQKPVPKAFQPKVPMEISPFSGELVPATELEEHMRLKLLDPRWQEQRKVEESRKSTLNLENVNVAANMKRLVSQRTDLFDVQNGVEISQEEIERRKRAATQSAWGATPTNKRR 2304459FC2735878 cwc16_schpo Protein saf4 saf4 cwc16 SPBC18H10.10c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MQGFNMGKYIPPEGPNAKRKFDKLRNVIRFEMPFPVWCNNCENIIQQGTRFNAVKKEIGSYYTTKIWSFSLKCHLCSNPIDVHTDPKNTEYIVASGGRRKIEPQDINERPAKAENDEKVPSDAIEALETQLTQQKSEKHNSSVINFIYEKNERLWSDPFVSSQRLRKQFRERKKIEKKQEAKDLSLKNRAALDIDILPPSSSDKDKALLLLDNELGKNKFIRKLDYRRTLMPSSRTFSTFAKFAETSFAKKDPFARKFVPSEKLRSEQRKFPTENLKGEKILEDNSVSLVNYEVSDDEG E64CEDDDE987859C rsmb_yeast Small nuclear ribonucleoprotein-associated protein B SMB1 Sm protein B YER029C protein protein yeast Saccharomyces cerevisiae Baker's yeast MSKIQVAHSSRLANLIDYKLRVLTQDGRVYIGQLMAFDKHMNLVLNECIEERVPKTQLDKLRPRKDSKDGTTLNIKVEKRVLGLTILRGEQILSTVVEDKPLLSKKERLVRDKKEKKQAQKQTKLRKEKEKKPGKIAKPNTANAKHTSSNSREIAQPSSSRYNGGNDNIGANRSRFNNEAPPQTRKFQPPPGFKRK 0A1078D5AA241430 0A1078D5AA241430 slt11_schpo Pre-mRNA-splicing factor cwf5 Complexed with cdc5 protein 5 ecm2 cwf5 SPCC550.02c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSHGPKGDINKQEWEDVEFPSICERCLGDNSYVRMTKEPLGQECKICSKPCTIFRWIKERGQKPGKTQICVGCARYKNCCQSCMLDLQFGLPIALRDAALKLVESGPTNDINREFFAQNQQRLLSNGETAYDSQEASAAARNLVKKVEKRELHSRPPKRKLDDVESKQILKEARASDASLNAERPLFPVKKIINGNVSLSINMEPPKDKKIASLFLIGVEDELADYKIRKHFEQYGPLKSVVCSHRAKCAFVNFKTRSSAEIAAAASPDGNVVIEGFRLKVQWGKPRSLGGPEGEVRNAKLADLVMRGSSHGNKTSQKSTIKNIENEDHENTKSPAVAIPIDPNQPRYRSQIPR 5283C11C4BD504AA sa145_schpo Pre-mRNA-splicing factor sap145 sap145 Spliceosome-associated protein 145 SPAC22F8.10c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MYLLTRPKHCCLDFLLMAEIQTAQNPLKELEKILERNNKQKNKKSRNQVRREKKKLLREKTNSGAKLAEKNSDDKDQLTENNDNLYNDKKSNGNFYDTNKTDSVDGMVYTTIVDSVELDPNDPLIEQFKDVFNRFKADGQEKDFEDTDKGQIMYSDDEILSEGEEDALQKQQEEKLSKKKLRKLKRMTVAQLKMLSEKADVVEWWDVSSLDPLFLTHLKAYPNTVPVPRHWNQKRDYLSGQRGIERQLFELPSYIRATGIVQMRNAVHENEADMPLRQKMRERVQPKMGKLDIDYQKLHDAFFRYQTKPVLTGFGECYFEGKELEADVKEKRPGDISEELREALGIAPGAPPPWLFAMQRYGPPPSYPDLKIPGVNCPIPTGAQWGFHPGGWGKPPVDQFNRPLYGDVFGNVKPRIHAGTGSPVSTQHWGELEEFEEEESSEEEESEDVEYPTEEITERETIEEYQSASEPRSQREDLHAEPLTYFNQSNVEVDNVELRKNTQPSSDAANRDLYQVLPEKSTNISGFMGPQHQYDIPTAEDTLPQKRNAHSMLSSTNKGDVALNQSSNWQDELSELVSEQAMKVGAAKRQKTQSKRDKFRL 3A0B235301B594A4 prp11_schpo Pre-mRNA-processing ATP-dependent RNA helicase prp11 prp11 SPCC10H11.01 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSRRTRSRSPPRRSYNRERRDYRKYDDSEDQKGARYNRYVDDVSSRRDRHDSFRSHESNKIRRDNSWKHDKYSYEKRYQERDREYARSKNIPDQYIGRSPRPTSHRHAEEKEVDNKTKSDETNPVLQGSATEIKPQPRRSRFDRTERVGASLSVSEIQSENPRVDVIPKDKAVENNHQRNAEKPVASDKITDAKLLARLERVRAWKESKAKQEASKKEEHKLNTKPQVTAKDQNAMPSTGISGFEINRQKDTSDMKRNNRVHMDDEDGPRRMNLEDYQELWDQEDRGMLGNEQAASMEEDEVDPLDAYMASLVGTTDTIRPGLLNTEVIDPNANDDERMVISETLEEEENLLALAAKRSKKKDVITVDHSKINYEDFKKDFYVEPEELKNLSPAEVDELRASLDGIKIRGIDCPKPVTSWSQCGLSAQTISVINSLGYEKPTSIQAQAIPAITSGRDVIGVAKTGSGKTIAFLLPMFRHIKDQRPLKTGEGPIAIIMTPTRELAVQIFRECKPFLKLLNIRACCAYGGAPIKDQIADLKRGAEIVVCTPGRMIDVLSANAGRVTNLHRCTYLVLDEADRMFDLGFEPQVMRIINNIRPDRQTVLFSATFPRAMEALARKVLKKPVEITVGGRSVVASEVEQIVEVRPEESKFSRLLELLGELYNNQLDVRTLVFVDRQESADALLSDLMKRGYTSNSIHGGKDQHDRDSTISDYKAGVFDVLIATSVVARGLDVKSLQLVVNYDCPNHMEDYVHRVGRTGRAGHTGVAVTFITPEQEKYAVDIAKALKMSKQPVPKELQTLASQFLEKVKAGKEKAAGGGFGGKGLSRLDETRNAERKMQRKAYGEDEEDVETEAEAKSPLEKITPEKSTGDPTLDRVRAAVGGIAARAFANQTAQSNKLTQPISIIKTDGDEYKAKMEINDYPQQARWAVTNNTNIVHVTELTGTSITTKGNFYLPGKNPEPGEEKLYLWIEGPSELVVNRAITELRRLLLEGINHSLEGGNKPSASGRYTVV 7700C6A90B79192B 7700C6A90B79192B prp17_yeast Pre-mRNA-processing factor 17 CDC40 PRP17 SLU4 XRS2 YDR364C D9481.11 Cell division control protein 40 protein protein yeast Saccharomyces cerevisiae Baker's yeast MGLVDGYDTSSDSDLNFDEGKSVHEKKNGNLHEDTSYEPSSNNIHKRKSHFTKSELKRRRKTRKGDGPWGSWSSSDDETSQASETQKEDQDIFVHALAEDNLDSEQIEVEEVSHFYGKSEKDYQGRGYLYPPNDVDVDLREERISFRCYLPKKVIRNYPGHPEGTTALKFLPKTGHLILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVKIWDTETGKVKTRLHLNSTPADVESRPTNPHEFIVGLSNSKILHYDDRVSENQGLVQTYDHHLSSILALKYFPDGSKFISSSEDKTVRIWENQINVPIKQISDTAQHSMPFLNVHPSQNYFCAQSMDNRIYSFSLKPKYKRHPKKIFKGHSSAGYGISLAFSGDGRYICSGDSKSRLFTWDWNTSRLLNNIKIPGNKPITQVDWHPQETSKVICSGAAGKIYVCD 40AED5DB35319147 40AED5DB35319147 cwf19_schpo Pre-mRNA-splicing factor cwf19 Complexed with cdc5 protein 19 cwf19 SPAC30D11.09 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MEKEKLTNRTSTHKFNETDRETNHSRRHRHHHSRHRESKHGRHDRSERPSSREAGDRSRHERFSKEPLEVKKLPVENEYFDSKFASASSMPSSKDNPQNNDFTNSLQGLDFGTFGSRIQREPIDRKSNKPGEIFVGATLQNESSTSTEHKDIEQLETEINESGINYKIGDNGSRWRMMKLKRVFDMAQDQRRPVEEVALERYGSLKEFDFALEERDELELRKRTRKVQKEVPTGELYEKRCADEFKTRKDSGNGATYYKVIPDPSVNKDTPTESDLNRLKADLLRAQLKKDPNYESLEREYQKACDDFENSLHPSENSNSQATIPSKKRNFDDPTIDEMVQEEKLLNKQRKYGQNYEYAKQIAKDKTYSNNLDYLDENAGKLSNRMKRGDVSLAQISSGGDLKKINHVLDTCPLCLNYETQPLAPVISLSHRAYVSLPTQPELAKYHCLIVPTGHRINTLSCDEDEWDEIRNFMKCIALMFDSMNLGVIFYENAPSPQRYMHTAIECIPVSKRILSLAPAYFREALSTSDEEWSQHRKIIDTLEGSKKYGKWAFRKMMVKELGYFHVWFSIDGGYGHVVEDEKAWGRHDQVPRQVFASMLNLPPEVIRRKGSWTGKKDPREDMFRSRFEKFDWTKGLID 95F79E570802DA1B cwc15_schpo Pre-mRNA-splicing factor cwf15 Complexed with cdc5 protein 15 cwf15 SPBC337.06c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MTTAHRPQFDPARGHSEMAPTRITSSRALPAHLKLKYRQESQGTEEEVRKQDLREALLRAEAAHFATQEHGASSEEVSQNSKLIEGFTSPSTDDKPNNDVEVDYQELLRQTLEADEDASDSDDSVDSSNKNSEVSIKRRKTESNSQESVDSSNSESSDEESDSEDETQQLLRELENIKQERKREQMLQEEKNRALEQEKREREIAFGNELLNKASSGSFQVKRRWDEDVVFRNTHKGVDDTPRPGFVNDMLRSEFHKKFLARFVD 3F99C03BC06CD67B luc7_schpo U1 snRNP-associated protein usp106 usp106 luc7 Protein luc7 SPCC16A11.13 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MAAEQRKIIEQLMGSNLSNFTSRGLVHFTDRKVCRSFLCGICPHDIFTNTKMDLGPCPKIHSDKLKSDYERASYSHDYGYEWDYLEDLERHVDDCNKRIDIAEARREKTKEEEERIDELMRDIIHTDHSIEVIITEMEALAKRKLVNDAVKHFIELNRLKTYRKELYDEVISMNEIPSQASTTHQKLQVCDICSAYLSRLDNDRRLADHFSGKMHLGYAMLRNIARDLRAQLEDREKSRDKKDGEKQRDNLASFEDKISTSFVA DC74E10B3AA84F2F prp46_schpo Pre-mRNA-splicing factor prp5 Pre-mRNA-processing protein 5 Complexed with cdc5 protein 1 prp5 cwf1 SPBP22H7.07 pi024 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MTEAKNISDDTDVLSLTTNSLRTSKTLFGAEFGSVTSFDDTVAQNLKRTYKEHLEYGSVLGGTVGKRKNRHYEEDTIGSNALTVRADSENPSSQVITKFSDPNKKIAGQVSMQSLEKIKGVPEAAHRIAGESQASLVKRTLAEQIRPEWHAPWTLMRVISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLHPTLDVLVTAGRDAVARVWDMRTRQNVHVLSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLAAGKTLTTLTHHKKTVRALSLHPDEFTFASGSSDNIKHWKFPEGAFMGNFEGHNAIVNTLSINSDNVMFSGADNGSMCFWDWKSGHKYQELQSVVQPGSLDSEAGIFASSFDKTGLRLITCEADKSVKIYKQVDNATPETHPNLPWTPSNLRRRY 941F3B31A8C19799 prp45_schpo Pre-mRNA-processing protein 45 prp45 snw1 SPCC188.11 SPCC584.08 cwf13 Complexed with cdc5 protein 13 Transcriptional coregulator snw1 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MALLSEELSSILPNPDFDDEEEDYVERETSHADERQIGVKFHIPPYGQRKGWFPSSPEDFGDGGAFPEIHVAQYPLDMGRKRSAKSAGNTLALQVTSSGAVDYNAIARQGHEHGELVQASFRDLIPLRARLGVGEISLEKPSDEQKQEVANKTKLALQKILSKQIAQSQPKSAVVQQRDDPVYIRYTPSNQMGQALSKQRIIKMVTAEQDPMEPPKFRHKKVPRGPPSPPPPVLHSPPRKVSAQEQQDWQIPPSISNWKNPKGYTIPLDKRLAADGRGLNDVEINDGFAKFSEALYTVERQAREEVRYRAIMRQKMAEKEKQEKEQRLFMLAQKAREDRMGRNAASSGPSHAKPRSTSVSSEERSRSRAGSFSHHSESENEDEDSEAFRRRQELRRERRRQAEKDLRLSRMGAEKRAKLAEKDRPRDVAERVALGLSKPSMSSDTMIDSRLFNQASGLGSGFQDEDSYNVYDKPWRAAPSSTLYRPGATLSRQVDASAELERITSESRYDVLGNAHKKFKGSDEVVESRAGPVTFEKDIADPFGVDTFLNNVSSKKT 916673DA5F9FE192 cwc21_schpo Pre-mRNA-splicing factor cwf21 Complexed with cdc5 protein 21 cwf21 SPAC4A8.09c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSYNGIGLPTPRGSGTNGYVMRNLSHVKKYDKNTNLQSNRNAKALEKRVQDPSISEHECRRQIESKLLLYREQLLEEVSSQHSTDAAASDSNTNFGTENPKPPKAIIKDEQSQSKTKSLDEADVEILVQKYREQLLKELQLQKSTEKGKNFESILQPQKRKETRGFHSKNDDDGRLEERDDLRSSVDDDYYDYPRYSERKSLNSKRHVDNYNENRRRHYDSYSSYDELERRRSSNESYSRRSELPRRDYNRHDERERYSYHRRRERSNSPSYTKNESIPVVDRDSSPEGGEIV 248C4D2649234CAE yhv5_schpo Uncharacterized protein C211.05 SPBC211.05 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MADRLRSQAKLEQLQARYVGVGNAFTTKYEWMVNQHRDTLSSVVGHPPLLAYMATALGEPRVQVRKNLLEKMIMPCGPPPPSNQF 7212FA5A4D040541 cwf14_schpo Pre-mRNA-splicing factor cwf14 cwf14 Complexed with cdc5 protein 14 SPBC24C6.11 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MPRLRTSRTKRPPDGFDEIEPTLIEFQDRMRQIENTMGKGTKTEMLAPIFQLHHQRSRYIYDLYYKREAISTELYNWLLKQNYADGNLIAKWKKPGYEKLCCLRCIQTAESKFGSTCICRVPKSKLDKDQRVRCTHCGCNGCASCD CF21C81738F746C7 cwc2_schpo Pre-mRNA-splicing factor cwf2 Complexed with cdc5 protein 2 Pre-mRNA-processing protein 3 prp3 cwf2 SPAC3A12.11c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSENGLEQEVTVEEKNNDVTEKILVEGEKSKEYEETPRKVKIVKRKKQPARKQIETRPEYEMEPEQPGQVYNLWYNKWSGGMRQDPLKSQVKSETRCVISRDSGYTKADKNPGSFFCLYFARGMCSEGSKCEYLHRLPKDTDFFNANVDCFGREKHADYRDDMGGVGSFLRQNYTLYVGGITPTDDIEEIVSRHFAEWGDIERIRVLNSRGIAFITYLNEANAQFAKEAMAHQSLDHDECLNVRWATTDPNPASQARNQRRLEERAANAVKKLLPKQFLLDLEETKNGKSGNRKRKLELEFGLKGYVPSDDLLYADGANSVHNQLAANEFPNKSQSEEGSNDDHKSVTTTESQNKFVNSQILSDLQVAKQAVHTNQSALVSYYDSDED 5CD36A5C880077DE 5CD36A5C880077DE yere_schpo WW domain-containing protein C2F3.14c SPAC2F3.14c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSSSKDCKATSNVDQTIPASNVNSGDFISSNTSSSNSENSNIQGKHYTQVGEDADNSFISENTPKNTFESTQTYENLESISKNEPTSEASKPLLNELVPEEPLPREPPLPNEPVPEEPLPGEPPLPDEPVPEEPLPGEPPLPNEPVPETNCHKESPLSDETVSETSKNDTSNSPTNENQAQPSIAWSEGHRIAAIWDPSQQAYYFWDTLTNTTSWNNPLEDEEQTSPLDYTAKVQFNRLSGKFMPKWASPELRSEENKAHKHMEQYFDINSSLNSHNGQSLLAERRNKRYTRKEMEQMKRRTKEKKEMKRRALYDIASDEKDFRRRKIIRY EA888EACC4CBB7B1 yju2_schpo Splicing factor YJU2 cwf16 Complexed with cdc5 protein 16 Pre-mRNA-splicing factor cwf16 SPAC9.13c SPAPJ735.01c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSERKVLNKYIPPDYDPSIRPPKKKKKFQGPNGGKLTVRLMTPFSMRCHTCGEYIYKGKKFNARKEKTGEKYFSIDILRFYIRCTRCAAEITFITDPKHADYAAESGASRNYEPWHEKRLQEYEENELAERNDIPEEDEMEKLEQKTLDTKRQMQISDALDELREKSARRSRVNIDDAIALLKEDAYGSIEEEESKKRKFEEEEIDREAKSLFSSQDGEIIRRLNAETTVEKELPKPIDLVSEKLATSNIPNFQPPKYAKRKMEKKKVLV 3A403699FCC655CE smd3_schpo Small nuclear ribonucleoprotein Sm D3 snRNP core protein D3 smd3 SPBC19C2.14 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSLCIKLLHETQGHIVTMELENGSTYRGKLIEAEDNMNCQMRDISVTARDGRVSHLDQVYIRGSHIRFLIVPDMLRNAPMFKVGPGRSVPLPTRGRR 4B0A6627BE7D4608 urn1_yeast Pre-mRNA-splicing factor URN1 URN1 U2-U5-U6 snRNP, RES complex and NTC-interacting pre-mRNA-splicing factor 1 YPR152C protein protein yeast Saccharomyces cerevisiae Baker's yeast MRGEWQEFKTPAGKKYYYNKNTKQSRWEKPNLKKGSNLESNAKESQTERKPTFSLELVNGWHLIIYNDGTKLYFNDDSKEFKNDISQEDDSRCRSLIESLDKEKLVLLIGVARGYTMREEDIDKILESCNEEIHLFKRNQDEVERKDEISEEAGDVKSPLQESHTGLVSGYGSSSGEEDEEEDEEEDEENEEQIVNQDISIIDDLNRIDTDDIDERNIFFELFDRYKLDKFSTWSLQSKKIENDPDFYKIRDDTVRESLFEEWCGERSGNATAEESDSEDNSEDDSEVLEPTKYHYLAQIVANAGTIAPDTIPQDIRKQQKALYKAYKIKEYIPSKRDQDKFVSQLLFYYKTFDLEQRKEIFCDCLRDHERDFTGAVESLRQDKELIDRWQTLLKAPADSSSIEDILLSIEHRCCVSPIVVTEPRYYVVGILEKTVVWVRWLAAEVGPSSRFTPVGAGNEPINPE B32285888B7DB772 prp46_yeast Pre-mRNA-splicing factor PRP46 CWC1 PRP nineteen-associated complex protein 50 PRP19-associated complex protein 50 P2594 YPL151C PRP46 NTC50 Pre-mRNA-processing protein 46 Complexed with CEF1 protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDGNDHKVENLGDVDKFYSRIRWNNQFSYMATLPPHLQSEMEGQKSLLMRYDTYRKESSSFSGEGKKVTLQHVPTDFSEASQAVISKKDHDTHASAFVNKIFQPEVAEELIVNRYEKLLSQRPEWHAPWKLSRVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWDVVAGKTMKVLTHHKRSVRATALHPKEFSVASACTDDIRSWGLAEGSLLTNFESEKTGIINTLSINQDDVLFAGGDNGVLSFYDYKSGHKYQSLATREMVGSLEGERSVLCSTFDKTGLRLITGEADKSIKIWKQDETATKESEPGLAWNPNLSAKRF 0E888F566A5414BD 0E888F566A5414BD clf1_schpo Pre-mRNA-splicing factor cwf4 Complexed with cdc5 protein 4 syf3 cwf4 SPBC31F10.11c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MTSEAPRVKNKNPAPIQISAEQLLREAVERQDVAFVPPKINITDLEELQEFQGRKRKEFEDAIRRNRLAMGHWMRYGQWELDQKEFARARSVFERALDVDSTYIPLWLKYIECEMKNRNINHARNLFDRAVTQLPRVDKLWYKYVYMEEMLGNITGCRQVFERWLKWEPDENCWMSYIRMERRYHENERARGIYERFVVVHPEVTNWLRWARFEEECGNAANVRQVYLAAIDALGQEFLNERFFIAFAKFEIRQKEYERARTIFKYAIDFMPRSKSMELYKEYTHFEKQFGDHLGVESTVLDKRRLQYEKLLKDSPYDYDTWLDLLKLEESAGDINTIRETYEKAIAKVPEVVEKNAWRRYVYIWLNYCLFEEIDVKDVDRARKVYQEALKLIPHKKFTFAKLWLMYAMFELRQRKIDVARKTLGRALGMCPKPKLFRGYIEFEDAIKQFDRCRILYEKWILYDPEACAPWLGYAALETKLGDSDRARALYNLAVNQPILETPELVWKAYIDFEFEEMEYGKARSIYQQLLRTAPHVKVWISFANFEIAHLEDDDEEPPNEEVASPTAVVRARNVFENALAHLRQQGLKEERVVLLEAWKQFEAMHGTEDTRKHVSSLMPQVVKKRRRLEDGSFEEYLDYLFPDTATDQGDKMRKMLELSRKWKEEMAKKKLEA 1AFAA23A68CB2A9F yo314_yeast Uncharacterized protein YOR314W 06123 YOR314W protein protein yeast Saccharomyces cerevisiae Baker's yeast MTMIRFCGARQSAIISNASDAAAGTNKKRILNPLESLCLNDRIDEHRCKEVQLSSLRSLLYAMILNRTIGSETGVFSFLLFSFRYFGEERDLFYCFFSVFLLNITYLLD C347BF65EEF85121 C347BF65EEF85121 sap61_schpo Pre-mRNA-splicing factor sap61 sap61 Spliceosome-associated protein 61 SPBC36.09 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSESVLETERYAHEELERLQQAIVDRQVANPKAPRERLRLEHQSAQFLNQFRETSKKLLVSHESSDRLKDQEVARINADDDLTEFYKSLGEIQEFHKKYPDHKVEDLSQLYSIKPSQPGIDEIDTLFRGEEMYGRFMDLNECYEEYINLSNVQHISYLEYLKNLEDFDQIPKPEKNQTYINYITHLYEYLVSFYRRTHPLSNLDKIIAVFDTEFDAAWEAGLPGWYSHNAEAEKDGKDSTEAFYCEVCQKFFGKITVFEAHKKSKAHNKAVKRMQSSSPSTTSNTNEKQKGPKAIARIEFLIKKLTSLLDDVRKDTRENVVRRQTLTAAERLAEVEAAEREAFEQSTPSVSVEGNQDEESDQDDEEKIYNPLKLPLGWDGKPIPFWLWKLHGLGKEFPCEICGNYVYMGRKAFDKHFTEQRHIYGLKCLGISPSPLFNQITSIDEALQLWQKYKVDSKKRETTMASLNEMEDDEGNVMSEKVYNDLKAQGLL 5208F677B10E9B95 prp31_schpo Pre-mRNA-processing factor 31 prp31 SPBC119.13c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSLADELLADLDDIEETTESTITDELGPDAKKRRLELQLEEGNGISAELENDLDITKISDSAQKLPSEVANKFNDNNENIYQLLNSTRLRDIIEGTEKYKGTEKQAITGNIEDDLEYHLIVDSNSIAMEIDDEILRLHRLVKEWYHDRFPELSSLVLNAFDYCKTVSSLLNDLDNSKTKLSFLPSATVMVIATTATTTVGKPLPDEMIKNVKNCCEAIQQLGEEKQKIIEYVQSRISVVAPNLSAVVGSTTAANLIGIAGGLTRLGKFPACNLPALGKRRLTTIGINNPAVSGDYGFLYMSEIVQKTPPDVRKQAIRMTAAKVALAARIDSIHEYPDGSFGISARKEVERKIEKLLEPPSQKPTVALPVPDDRPKRRRGGRRIRKMKEQYAVTELRRLQNRVAFGKEEAEVFNFDETEGLGMLGQEGEGKIRAVSIDSRTKLRLPKARKAQLQSMAQKNPLAASGLQSSLSFTPIQGIELVNPLLQRQQKVEEANKWFRDGVFTQIKKDSNEPKNKFS EA2CBCB489438E6E prp45_yeast Pre-mRNA-processing protein 45 YAL032C PRP45 FUN20 protein protein yeast Saccharomyces cerevisiae Baker's yeast MFSNRLPPPKHSQGRVSTALSSDRVEPAILTDQIAKNVKLDDFIPKRQSNFELSVPLPTKAEIQECTARTKSYIQRLVNAKLANSNNRASSRYVTETHQAPANLLLNNSHHIEVVSKQMDPLLPRFVGKKARKVVAPTENDEVVPVLHMDGSNDRGEADPNEWKIPAAVSNWKNPNGYTVALERRVGKALDNENNTINDGFMKLSEALENADKKARQEIRSKMELKRLAMEQEMLAKESKLKELSQRARYHNGTPQTGAIVKPKKQTSTVARLKELAYSQGRDVSEKIILGAAKRSEQPDLQYDSRFFTRGANASAKRHEDQVYDNPLFVQQDIESIYKTNYEKLDEAVNVKSEGASGSHGPIQFTKAESDDKSDNYGA FE5A724186D7FE84 FE5A724186D7FE84 ru2a_schpo U2 small nuclear ribonucleoprotein A' lea1 SPBC1861.08c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MRLNAEFLSQVPSFISPLKETELDLRWYQIPIIENLGVLRDVHDAIDFTDNDIRYLGNFPRMKRLQTLLCGNNRITAIAPDIGKVLPNLKTLSLAQNHLQEIADLDPLASCPQLTNLSCIDNPVAQKQYYRLYLIWRIPSLHILDFERVRRNERLRAEEVFGQIQNPTEIASSIMGVKSRVFDLAALVQSHPEANSPITTGYTLTPEEREKIKEAIKNASSIAEINRLEAMLLEGKIPK CAB29D7CE38D3938 smd1_yeast Small nuclear ribonucleoprotein Sm D1 YGR074W SMD1 snRNP core protein D1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MKLVNFLKKLRNEQVTIELKNGTTVWGTLQSVSPQMNAILTDVKLTLPQPRLNKLNSNGIAMASLYLTGGQQPTASDNIASLQYINIRGNTIRQIILPDSLNLDSLLVDQKQLNSLRRSGQIANDPSKKRRRDFGAPANKRPRRGL 9929F21EB9218447 9929F21EB9218447 rse1_yeast Pre-mRNA-splicing factor RSE1 RSE1 YML049C YM9827.03C SAP130 RNA splicing and ER to Golgi transport factor 1 Spliceosome-associated protein 130 protein protein yeast Saccharomyces cerevisiae Baker's yeast MWGGGKMAVVSLSPHTAKMRKLFGQASTTMAYDGLKREAERRTRSDHNITMVAKDDELYLYHLTLKKQTNFVHSCIGHFVDLEAGSKREQSQLCVATETHLELYDTADGELKLIAKFQNLFATITSMKSLDLPHSGSRAKASNWPTFLALTSDSGNLSIVQIIMHAGALRLKTLVNQPLTRTTLRRVSPISYMEIDPNGRCIILSSVEQNKLCFLVDYAQKLRISSPLEIIRPHMVTLDMAVVDVNFNNPCFVTLEIDNAATQLSVHLIFYVLELGLNHIVKKADYLVNPSANFVLSLPDLSRYNITTSLSDNNYDADYDTLFNPFVVIGFENHILVKDMNGFFSLKVEIPKRSITNSRHKNVTIISGIVQKLKNDFFVLLQSNHGDLFKLTVSPDTNDRNRPLVQLSYFDTIQNSHQLHIFKNGYLFALSEMNNNFLFQFEKLGVEKNDFSNVLTSKDPNKSLVFEPSIKLQNLSILSQQLNLNPSIKSQIVSDSPLSIATKHFTNNKIITLTNAVNYSNLISTSLPPNATKLWLIPDPATTGDNNTLLFITFPKKTMILQIDNESMEELTPDEATRSAFKLSQDTTIHTCLMGSHSIIQVCTAELRHIVPTGKSRYSNKLTWVPPAGIRIVCATSSKTQLIISLSNYELVYFKIDVSSDSLIELTTHPELDTMPSKVAIVQDTQHADLLAIADNEGMIKIMSLKDQKEDFLTVISLQLVSEKISDMIMVRDSSIGQLNLHVGLENGVYMKFHIGDVDGSFTDIKRRFLGLKPVSLSYLREISVSLNNEEEEEEEEDDDDEKEEEEINSSGAKWMSCVVCHSSSTWVSYTWKNVWTIRQLKDQNMLSCSKFVNADVAINGVCSISSSGRLNIGRVSNFPTLDNWFHVHESSVNKQENGGGDESNEEEEDEMEEEMEMLQISTFRPRTILSFPNNPKSILFIDNHSGKKQCRISLQIDGECLKFGSSDHLYKILDDIDCVSAAIIDFTRQADHLIICAGDKRLLTYKILVNKDKLSFDIELLHQTEIISPIHAMLKFKNFLLTAMGSTIVLYGLGKKQLLRRSVTQTPVSITKIVSMHQWNYERLAVGDIHESVTLFIWDPAGNVFIPYVDDSVKRHVTVLKFLDEATVIGADRYGNAWTLRSPPECEKIMSNHDPSELSNGAIKYPLDVITLQQKLPNTYDCKFKFQLLNHFFVNDIITDFHILDSLSNSDRPGCIYMGLQGTVGCFIPLLSKGNVFMMGNIENIMAEADDTFYLDYESRKKNNNMRKEDDEEESGSVVLQGRHGIEDEIICEGSCSILGRDHQEYRSYYAPVRKVIDGDLCENFLRLSLNEQEFLAKNLKSVQVEDIIQTINEVRTNYM 4D92837F5C267D67 4D92837F5C267D67 prp1_schpo Pre-mRNA-splicing factor prp1 prp1 zer1 SPBC6B1.07 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MANFYPDFLNMQPPPNYVAGLGRGATGFTTRSDLGPAQELPSQESIKAAIEQRKSEIEEEEDIDPRYQDPDNEVALFATAPYDHEDEEADKIYQSVEEHLSKRRKSQREKQEQLQKEKYEKENPKVSSQFADLKRGLSTLTDEDWNNIPEPGDLTRKKRTKQPRRERFYATSDFVLASARNENQAISNFAVDTQAGTETPDMNGTKTNFVEIGAARDKVLGIKLAQASSNLTSPSTIDPKGYLTSLNSMVPKNANDLGDIRKARKLLQSVIETNPKHASGWVAAARLEEVANKLSQAQSLILKGCENCSRSEDVWLEAIRLHPAAEAKVIIANAVKKLPKSVTLWLEAEKLENQAQHKKRIIKKALEFNPTSVSLWKEAVNLEEEVDNARILLARAVELIPMSIDLWLALARLETYENAKKVLNKARQTIRTSHEVWIAAARLEEQQGNVSRVEKIMARGVSELQATGGMLQRDQWLSEAEKCETEGAVITAQAIINTCLGVGLDEEDQFDTWLDDAQSFIARKCIDCARAVFAFSLRVYPKSEKLWLRAVELEKLYGTTESVCSILEKAVESCPKAEILWLLYAKERKNVNDIAGARNILGRAFEYNSNSEEIWLAAVRIEFVNNENERARKLLARARIESGTERIWTKSISLERILDEKDRALQLLENALKIYPHYDKLYMMKGQIFEDKEQIELARDAYLAGTKVCPYSIPLWLLLAKLEEKQSVIRARVVFDRAKVKNPKNEFLWLELIKMELRAGNISQVRAALAKALQECPSSGLLWTEAIWLEPRAQRKTRATDALRKCEGNAHLLCTIARMLWLEKKADKARSWFLKAVKADQDNGDVWCWFYKYSLEAGNEDQQKEVLTSFETADPHHGYFWPSITKDIKNSRKTPQELLHLAINVL 4690EDBCA9F1AA3B prp8_yeast Pre-mRNA-splicing factor 8 PRP8 DBF3 DNA39 RNA8 SLT21 USA2 YHR165C protein protein yeast Saccharomyces cerevisiae Baker's yeast MSGLPPPPPGFEEDSDLALPPPPPPPPGYEIEELDNPMVPSSVNEDTFLPPPPPPPSNFEINAEEIVDFTLPPPPPPPGLDELETKAEKKVELHGKRKLDIGKDTFVTRKSRKRAKKMTKKAKRSNLYTPKAEMPPEHLRKIINTHSDMASKMYNTDKKAFLGALKYLPHAILKLLENMPHPWEQAKEVKVLYHTSGAITFVNETPRVIEPVYTAQWSATWIAMRREKRDRTHFKRMRFPPFDDDEPPLSYEQHIENIEPLDPINLPLDSQDDEYVKDWLYDSRPLEEDSKKVNGTSYKKWSFDLPEMSNLYRLSTPLRDEVTDKNYYYLFDKKSFFNGKALNNAIPGGPKFEPLYPREEEEDYNEFNSIDRVIFRVPIRSEYKVAFPHLYNSRPRSVRIPWYNNPVSCIIQNDEEYDTPALFFDPSLNPIPHFIDNNSSLNVSNTKENGDFTLPEDFAPLLAEEEELILPNTKDAMSLYHSPFPFNRTKGKMVRAQDVALAKKWFLQHPDEEYPVKVKVSYQKLLKNYVLNELHPTLPTNHNKTKLLKSLKNTKYFQQTTIDWVEAGLQLCRQGHNMLNLLIHRKGLTYLHLDYNFNLKPTKTLTTKERKKSRLGNSFHLMRELLKMMKLIVDTHVQFRLGNVDAFQLADGIHYILNHIGQLTGIYRYKYKVMHQIRACKDLKHIIYYKFNKNLGKGPGCGFWQPAWRVWLNFLRGTIPLLERYIGNLITRQFEGRSNEIVKTTTKQRLDAYYDLELRNSVMDDILEMMPESIRQKKARTILQHLSEAWRCWKANIPWDVPGMPAPIKKIIERYIKSKADAWVSAAHYNRERIKRGAHVEKTMVKKNLGRLTRLWIKNEQERQRQIQKNGPEITPEEATTIFSVMVEWLESRSFSPIPFPPLTYKNDTKILVLALEDLKDVYASKVRLNASEREELALIEEAYDNPHDTLNRIKKYLLTQRVFKPVDITMMENYQNISPVYSVDPLEKITDAYLDQYLWYEADQRKLFPNWIKPSDSEIPPLLVYKWTQGINNLSEIWDVSRGQSAVLLETTLGEMAEKIDFTLLNRLLRLIVDPNIADYITAKNNVVINFKDMSHVNKYGLIRGLKFASFIFQYYGLVIDLLLLGQERATDLAGPANNPNEFMQFKSKEVEKAHPIRLYTRYLDRIYMLFHFEEDEGEELTDEYLAENPDPNFENSIGYNNRKCWPKDSRMRLIRQDVNLGRAVFWEIQSRVPTSLTSIKWENAFVSVYSKNNPNLLFSMCGFEVRILPRQRMEEVVSNDEGVWDLVDERTKQRTAKAYLKVSEEEIKKFDSRIRGILMASGSTTFTKVAAKWNTSLISLFTYFREAIVATEPLLDILVKGETRIQNRVKLGLNSKMPTRFPPAVFYTPKELGGLGMISASHILIPASDLSWSKQTDTGITHFRAGMTHEDEKLIPTIFRYITTWENEFLDSQRVWAEYATKRQEAIQQNRRLAFEELEGSWDRGIPRISTLFQRDRHTLAYDRGHRIRREFKQYSLERNSPFWWTNSHHDGKLWNLNAYRTDVIQALGGIETILEHTLFKGTGFNSWEGLFWEKASGFEDSMQFKKLTHAQRTGLSQIPNRRFTLWWSPTINRANVYVGFLVQLDLTGIFLHGKIPTLKISLIQIFRAHLWQKIHESIVFDICQILDGELDVLQIESVTKETVHPRKSYKMNSSAADITMESVHEWEVSKPSLLHETNDSFKGLITNKMWFDVQLRYGDYDSHDISRYVRAKFLDYTTDNVSMYPSPTGVMIGIDLAYNMYDAYGNWFNGLKPLIQNSMRTIMKANPALYVLRERIRKGLQIYQSSVQEPFLNSSNYAELFNNDIKLFVDDTNVYRVTVHKTFEGNVATKAINGCIFTLNPKTGHLFLKIIHTSVWAGQKRLSQLAKWKTAEEVSALVRSLPKEEQPKQIIVTRKAMLDPLEVHMLDFPNIAIRPTELRLPFSAAMSIDKLSDVVMKATEPQMVLFNIYDDWLDRISSYTAFSRLTLLLRALKTNEESAKMILLSDPTITIKSYHLWPSFTDEQWITIESQMRDLILTEYGRKYNVNISALTQTEIKDIILGQNIKAPSVKRQKMAELEAARSEKQNDEEAAGASTVMKTKTINAQGEEIVVVASADYESQTFSSKNEWRKSAIANTLLYLRLKNIYVSADDFVEEQNVYVLPKNLLKKFIEISDVKIQVAAFIYGMSAKDHPKVKEIKTVVLVPQLGHVGSVQISNIPDIGDLPDTEGLELLGWIHTQTEELKFMAASEVATHSKLFADKKRDCIDISIFSTPGSVSLSAYNLTDEGYQWGEENKDIMNVLSEGFEPTFSTHAQLLLSDRITGNFIIPSGNVWNYTFMGTAFNQEGDYNFKYGIPLEFYNEMHRPVHFLQFSELAGDEELEAEQIDVFS 8F4F6F89D34D3508 8F4F6F89D34D3508 syf2_schpo Pre-mRNA-splicing factor syf2 syf2 SPBC3E7.13c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MDSPSHSREARVEKLKKIREQMRKSSHENRKEVVQEHSRMRIDPALERRLERKRMEAEEELAKIETEEEGGDFERRRAWDWTIEESEKWDQRLRKKKQTIQNVAFSDYHSQASKDYNRGIRDLKPDYEKYDKDKKEEKSKSRSVALYDEAERLDWVSNKPDKEHVERLVESIKKQDQRRLKNTKRRGTDEEDHITFINERNRKFNLKLQRFYSKYTKDIKEDLERGTAL 3858D6810D59DCF6 sap49_schpo Spliceosome-associated protein 49 sap49 SPAC31G5.01 SPAPB1A11.05 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSIREDRNQDATIYLGNLDEKVTDSILFELCLQAGPVVNIHIPRDRVRNSHNGFGFCEFLHEQDVEYACQILNQVKLFGKPIRVNRASQDRGVNTLIGANLFVGNLDPLVDERVLYDTFSALGQLVKAPQVARDENGRSKGYGFVSYDSFETADAAIEAMNNQFLMNKPITVSYAFKREGKGERHGDIAERKLAAAAKKNKVAVTPQSTLPPGFSPATPAPTSAANTPATIAATSIPPVPNVPLVGATTAVPPLSIPNVLPFTAAQHFPGMPAMPMMNVPMGPGGAPLVPPPPPGMVMASPSPAAATIPGAPVMPNIPFYQTINAQNGYSQQQRR 5F05F7CDF7144400 cwc25_schpo Pre-mRNA-splicing factor cwf25 Complexed with cdc5 protein 25 cwf25 SPBC146.05c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MGGGDLNMKKSWHPLLMRNQEKVWKDEQAHKEEMKRVEQLRREIEEERQLLELHRLQEAAGGKKRKDRVEWMYAVPNTNGPNRDSSEMEEYLLGRRRLDDLLKDKIEDQNNSLEKTEFIALQNANSLQDTQAKLRLDPLLAIKQQEQKQLQTLMEKRKYSLDSDRKSKERRHRDRHHRSNQDRSRERSDNEQHSSDKREHSRRSYRNDRNNWRERTHNDRYRHRDKYDSGYFKKHYDDDMRFDQGHFQDERDLKKYVRTSRQYSRSPSPDFRTRNHQFHSRDSQPITQRHTDIESRLQKMQDNAKELDESRRKKIELLEKKERDEEQFLEKERRDTARKWDNQGDFIRNMRKEIYSGDSVSLADRVNSSRHNMLRP 7CAD5F99CF165B15 bud31_yeast Pre-mRNA-splicing factor BUD31 BUD31 Bud site selection protein 31 CWC14 Complexed with CEF1 protein 14 YCR63W YCR903 YCR063W protein protein yeast Saccharomyces cerevisiae Baker's yeast MPRIKTRRSKPAPDGFEKIKPTLTDFEIQLRDAQKDKSSKLAAKSNEQLWEIMQLHHQRSRYIYTLYYKRKAISKDLYDWLIKEKYADKLLIAKWRKTGYEKLCCLRCIQKNETNNGSTCICRVPRAQLEEEARKKGTQVSFHQCVHCGCRGCASTD 70A8B15F8DA6F85D 70A8B15F8DA6F85D cwf11_schpo Pre-mRNA-splicing factor cwf11 cwf11 Complexed with cdc5 protein 11 SPBC646.02 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MVLYKNKKKQIINYANSNWGQNEGVEFQETMLQCILEAVIVSKDAKQVLSLLHELKLFENFLWQRVNTEMSLNHINLTCMLLLYKSKYEYITWDLIDENRFQLFFEKVIEVSLSLNLSEVVYMIQFITLCFQFSNIEKLRKLVYQLTNISILNSLDNLDKVKYLLHDSSSLTKAFDSYKEKRPSIVEKFPLHNLLSRWIHSLLIKSISYAQTEKQEAKVTPLLAIINMSLVLLSAFPTRRFAHPVIEDSCFYTALRMSLYYDSNELFKKMTDDLNYVLKFPFDNTRGNEYEKEQKIRNDELVYYHLQLTLFSDFQKELGDLVFCTQTSLQQRQKLEEITSFLSFNSLKSLCSKCYLRTSFPEKYAIKVDFEFLKNVFINTYDRTRLVNDYDEIINFTLKDVLGERSVMDQENSLTNYFLLQNTAIQYLSISFFMRQQSKAYKKLLLRSLYAELLNFSEQYRRLSIKNATKNLTKDNFFSLNNFKVTSVAPPQIGQVLPQFVKCQMGLSRPGPFHSALRDLKNSIKSPFLCLIYISKDMEYKLLHGNALDPLEGVTDFTIATICNDDVGMFQSDMQSDSDNKSINVYLSPFYYHSLAGLGEYRPKQLKFNFALVLSPEANKYWLDLNILVSLLNRAKEFPKWFEDLFLGFGTPDICAFPNAGLNSIYARNLFNTVEQLQSVLPNCHVPSNLSTESLLIKFYTNQNKISADVTASDRHFLLPSNRLYTYNDKQLESILRGSQPGLTMVNGPTRCGKHVLVCKLLEVLQDTSPNDRTVVLSDSNFSMNTLFTLLEKARCFHQGHLLYLSDEGKDETLERYGTLSSWISKLPGLLREIGRLAASIQAPGSHDASPDTALYFRDAYIKRLWEKYLNTVDDKDSVDAYNRFPFHSYFGDKSKRPIETYNKDNFFDYATKLYGELEYMFQQLEEIRPFGLLRYYEDQELYALCQQSRIIGCTWTSLSTRLGTLKEKGFCFNNLIVMNSQNISESSITSILLSNCEPTGFDRLVLLGNQYLTSGNQDINNTSNGSLFKRLRYLKSRIIDLNTQYNVRESISSLCSSIYPLDIKTVDSSPNKRLDYGNSGFAHEVQFINVGAFKGSQETEPVSGYKQNLGEAEYAVALFQYMRMLGYPTNEIVICTLYESQVSLLNEIISVRCSHNSFFGQPAFVGTVEKLPSDKRVNFVIFTTVESKEASDHWNPKTFYKAFSACSYGLYVLCNRDLFRSTRGLEKLWNEIEKTPDKLLLTTGEIYPSSHKIGSSVETFEIENLLHLSNYVVEMTKKRLNTN F751A9F4B36534D5 smd2_yeast Small nuclear ribonucleoprotein Sm D2 SMD2 YLR275W L9328.5 snRNP core protein D2 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSSQIIDRPKHELSRAELEELEEFEFKHGPMSLINDAMVTRTPVIISLRNNHKIIARVKAFDRHCNMVLENVKELWTEKKGKNVINRERFISKLFLRGDSVIVVLKTPVE 7287070B10E090C0 7287070B10E090C0 prp16_schpo Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16 prp16 SPBC1711.17 SPBC17G9.01 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MLSHNQNDLLFTKLIDKLTDYMSSKDAATSLASRVLTIAKGSSSSTEFSNALHTFGRFSDNDSVLIYDLCKSIIGLETNLGISKDKLPGNDGSQVAGLVLSNRSGLKGREPKKSQLGLDVLAVQKKKEKSQVEGRSELSQVENDSLESIGNYDRVEFKRPKNPHEKHFRPLRQRSSVDDHQEFESEDDKYRRNSYSSWSGSNFESSNGSNRRRYRTQMEEPLSSKRRNRFGNGSRRDVDSSKYSHDSDYSYGAHSSWDARDVEYPEEDPESKADRQRWEEEQAHLDRDWYMNSESQNLLGDEVHNPFSDFETVEDRAHEAEFIEKQKKHLSIEASDRFKENSMWEKNRMITSGVSKAPGLESDYSLMEERRVHLLVDELRPHFLDGAEFSSKKVGDITSVRDPQSDLAINARLGSRLVRERREFRERQKAASAATSLAGTSLGNVMGLKDSNDEDAKAGTTPVKVAGRSEQSNKKDTEFARTKSYREQREFLPAFAVREQLLSVIRDNQVLIVVGETGSGKTTQLAQFLYEDGYHRNGMIGCTQPRRVAAMSVAKRVSEEMGVRLGSTVGYSIRFEDVTGPDTVIKYMTDGVLLRESLMQNNLEKYSVIIMDEAHERSLNTDILMGLLKKVLSRRRDIKLLVTSATMNSQKFSDFFGGAPQFTIPGRTYPVDIMFAKAPCSDYVEAAVRQVLQIHLSQPAGDILVFMTGQEDIEATCEIIADRLNQLHDAPRLSILPIYSQMPADLQAKIFDSAEPGVRKVVVATNIAETSLTVHGISYVVDTGYCKLKMYNSKLGIDTLQVTPISQANANQRAGRAGRTGPGIAYRLYTEMAYIREMFETTLPEIQRTNLSNTVLILKSLGVEEISDFDFMDRPPNDTLMASLYELWTLGALDNFGKLTTLGKKMSLFPMDPSLSKLIIIAEDYKCTEEIITIVSMLSVPSVFYRPKERAEESDAAREKFNVPESDHLMLLNIYQHWQRNGYSNSWCSKHFLHSKTLKRARDIRQQLVEIMSKQKISLESVSDWDIVRRVLCSAYFHQAACAKGIGEYVHLRSGMPCHLHVTSSLYGLGYLPDYVIYHELVLTSKEYMNIVTSVDPYWLAEFGGVYYSVKERFRNETESYDRVFSSKPQLDAQIAADRELDAKQKLAKNQEPVKSKRKSVIRAKPPRRVRGF 1B382AC72F2C2249 cus1_yeast Cold sensitive U2 snRNA suppressor 1 YM9408.02C YMR240C CUS1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MARTKSRKRSGNNQNKNASVVNNKAEIAAMIDARRLEQKKKGGVTNSKGKTNKVVDAKLEKEFKDVLQRFQVQENDTPKEITKDEKNNHVVIVEKNPVMNRKHTAEDELEDTPSDGIEEHLSARKRRKTEKPSLSQLKSQVPYPQIIEWYDCDARYPGLLASIKCTKNVIPVPSHWQSKKEYLSGRSLLGKRPFELPDIIKKTNIEQMRSTLPQSGLDGQDEKSLKEASRARVQPKMGALDLDYKKLHDVFFKIGANWKPDHLLCFGDVYYENRNLFEETNWKRMVDHKRPGRISQELRAIMNLPEGQLPPWCMKMKDIGLPTGYPDLKIAGLNWDITNLKGDVYGKIIPNHHSRSKKQGRNYFGALISFETPEFENSKEDTQANAENGRQDDKIDDEVEHKLDHFQEDISEVTSAEEKLERNEEESEKQLYTVLK 0204B3A666AF7336 0204B3A666AF7336 q9u523_drome alpha-Catr alpha-catenin-related alpha-catenin-related gene CG2987 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MYGITQSTVNNQRFRVRDMDNEQIMSTFGNIGHLLNIAVERFITIGEIIAEENIDIKGDMYEAAKEARDAGKSIERLCDISPLSGMELRHHIEPLKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNFTEFVRAFSVFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCVIVKENRDTVFCQIRRAMDLIHFVVKDSIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQLSYYEGSGEGNNNSDAYFSFLDDDLWKSEKNLPSAAGGGRMVNNTNFRKHLSSESLDLREELSLAFEKLFEKAHDFTDSPYISHNHRKNILSYCDNCKLEFDLYLNTIMKDQHEGGGGAGGVGGVGGGQVKGRSDPELGMLSSLEELCKQLVVSVSSQIEDFNESLKICSKLVKSFHVLATNYDIDNLNQRSSKFHDCCDHIFDICKLLQHIAPTERLQVQAKCLAINLRIYGPQVFIAAKILWKYSNSSAANENFESFSDMWKWLTNEISMIAKKILVSINTTKGDRDADAEKCESSSDKLTKSGVPATEDGEMVEYSGLEGKNNGDLNTYQSKWSEDLSDDNDILKRAKNMSAMAFLMYQFTKGNGSLRTTQDLFTQAEYFAEEANRLYKVLRHFSYQFPASDNKKGFLQHFR 7F07A87DD97E9705 yp257_yeast Uncharacterized membrane protein YPL257W YPL257W protein protein yeast Saccharomyces cerevisiae Baker's yeast MTAHANERISDVSPSARGSSSESKYDKLCRVLFFIAITKSSFTPEHILYKHSIFTDKPILADIVTFMYAAFVSIGWFLIWGERAYRTQEMGQPPMYSNINYHLLSFKKRHPKKFTCALWLVFFLAYTVLTVLIWLVQLIFRKGNVFQMLLQLIILDIAIALVNVAIAFTFEIYLSQKAAIEIRDEGLNNLDTA 9EFB6F4E1166160C yidc_schpo Uncharacterized WD repeat-containing protein C227.12 SPAC227.12 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MNENEGISLGELETRPFSEGITRFTKEQAAYYAEQKEKDRIKALKIPYEDSKVREYLRRYGEPITYFGEDALARRQRLQQLMIEKSLEGDNPLDVDQGASENIEKETYVQGSHELLVARKKIALYSLEKAKLRLKKEREISEIPVPEIVLSGKSSIEHLQKAELMGSQIGGERPIAIVRFSNNGNHFASGSWGGQVKVWNSDNLSEVQLFRGHTDRVSGLDWYPLCQAWDADSEQLTLATGAADNTVCLWKASQSTPLLRLEGHLARVGRVAFHPSGDYLVSASFDTTWRLWDVHTGVELLMQEGHSEGIFSIACQPDGSLVSSGGNDAIGRIWDLRSGKSIMVLDEHIRQIVAMAWSPNGYQLATSSADDTVKIWDLRKVSLAHTIPAHSSLVSDVRYIESGVNRFIATSGYDGCVKLWNPLNCSLIKSMVGHEEKVMSVDGYGDRFISSGYDRTIKLWYP 4D3703820FF54067 dhx15_schpo Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43 prp43 SPBC16H5.10c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MEPAQKKLRQESKNPYLAHLNNGDDSEEVVSSKGLTRRATTVAQAAKAEEGPNNFFNDKPFSQNYFKILETRRELPVYQQREEFLKIYHENQIIVFVGETGSGKTTQIPQFVLYDELPHLTNTQIACTQPRRVAAMSVAKRVADEMDVDLGEEVGYNIRFEDCSGPNTLLKYMTDGMLLREAMTDHMLSRYSCIILDEAHERTLATDILMGLMKRLATRRPDLKIIVMSATLDAKKFQKYFFDAPLLAVPGRTYPVEIYYTQEPERDYLEAALRTVLQIHVEEGPGDILVFLTGEEEIEDACRKITLEADDLVREGAAGPLKVYPLYGSLPPNQQQRIFEPTPEDTKSGYGRKVVISTNIAETSLTIDGIVYVVDPGFSKQKIYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFRKELIEQTYPEILRSNLSSTVLELKKLGIDDLVHFDYMDPPAPETMMRALEELNYLNCLDDNGDLTPLGRKASEFPLDPNLAVMLIRSPEFYCSNEVLSLTALLSVPNVFVRPNSARKLADEMRQQFTHPDGDHLTLLNVYHAYKSGEGTADWCWNHFLSHRALISADNVRKQLRRTMERQEVELISTPFDDKNYYVNIRRALVSGFFMQVAKKSANGKNYVTMKDNQVVSLHPSCGLSVTPEWVVYNEFVLTTKSFIRNVTAIRPEWLIELAPNYYDLDDFDNNKEVKSALQKVYQMAARSKKNARR DC2A25F145F5A5C4 smd1_schpo Small nuclear ribonucleoprotein Sm D1 snRNP core protein D1 smd1 SPAC27D7.07c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MKLVRFLMKLTNETVSIELKNGTIVHGTITSVDMQMNTHLKAVKMTVKGREPVPVETLSIRGNNIRYYILPDSLPLDTLLIDDSTKPKQKKKEVVRGRGRGRGRGTRGRGRGASRGF B568575B62600C64 aim4_yeast Altered inheritance of mitochondria protein 4 YBR194W YBR1404 AIM4 SOY1 Synthetic with old yellow enzyme protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDQKKDPSNNLTERRVSKVQRPNKKKVRNQVESLSRNLERNKEGQLLQTVSKGHLEADSGHSLGREKENGELGIRSIFYDKDWNPRGTAPSHYRNIPYNPATFKRRTEVQARLGNLENIKIPK AF25FE81D22D4C8C smd2_schpo Small nuclear ribonucleoprotein Sm D2 snRNP core protein D2 smd2 SPAC2C4.03c Complexed with cdc5 protein 9 cwf9 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MADLVDKPRSELSEIELARLEEYEFSAGPLSVLQQAVKNHDQVLINCRNNKKLLARVKAFDRHSNMVLENVKEMWTEKKRTASGKKGKAINKDRFISKMFLRGDGVVLVVRIPSA EF39B51D94356C33 sf3b6_schpo Splicing factor 3B subunit 6-like protein Pre-mRNA branch site p14-like protein SPBC29A3.07c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MPPSTVNQEVNSILFIKNLSFKITAEEMYDLFGRYGPVRQIRLGNTVQTRGTAFVVYENVQDARRACEKLSGYNFMDRYLVVHYYNPERAKVDGQDLAARYAALEQVKQKYGVQL 75AAC211FB503AAD prp38_schpo Pre-mRNA-splicing factor 38 prp38 SPBC19C2.08 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MADFLARDYRSQGEAAHEMLPTFLIGKILRERIVDSIYWKEQCFGLNACSLVDRAVRLEYIGGQYGNQRPTEFICLLYKLLQIAPEKEIIQQYLSIPEFKYLRALAAFYVRLTWDDVEVHQTLEPLLRDYRKLRIRTNSEIRLTYLDEVVDDLLNAEVVCDISLPPLRSRLQLEDLDLLEPLSSSSDEEDDDEEQISKLESNEGAVDRNI EDA154276C34929B saf1_schpo Protein saf1 saf1 SPCC663.11 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MLSKRGLNPVQAESRKKKKREQIKVREERAKRHEERLSHRNMSQMERQLSELTQLESSQALNAHDKQLLQNLQRDMAIMKKKNIHGHRVGRVESDKTKEAERQHKPRKPFIPKNPKRSIYYDPIFNPYGVPPPGMPYREKEELSSETDESVIDIPLPSEEYPFEDPKPREKKNKSFKPKHHKKQDINASSAQPKSTTTTEAAANTKDIEEETMIEYSAQPVVRDLRQEAAQFLPAAFQRQKLAKGQKIGQPDRDVSSQVQEDKDEEIDNFYKEIGGYL 4A53E3740FA05A93 ylk3_schpo Uncharacterized protein C1782.03 SPAC1782.03 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MPIDTPLIPHKPISRYRSGRLEGLESESSSESDYEEVSDSHDQENSISSSRHVITPVFEKEGISETKTSSNFQNINPVQTIDNSASEYETDASSAEGGSNSAASSSEEEDSSDSEYEMELRRRTLLLPPKFTSKVIKNRAKANEEDTEVLKKVTSQKILEETIKRELLLKETKNNNELLNDIDDTDGIDPQSEYELWKLRHLLRKKRDKEKSLELEREKMAIEERRLMNSEEREAQDLKDAEASRRGKKKSSMQFLQKYYHKGAFYQNEDIVSKRDYSEATEGEVLNKDLLPKPMQIRGDLFAKAGQTRWTHLANEDTTKEGSAWYDPKNPILQKNLHRLGGLHSDSPLSKRKRT C4E97823B2598A00 dre4_schpo Pre-mRNA-splicing factor dre4 dre4 hgp1 Hyphal growth protein 1 SPAC13C5.02 DNA replication protein 4 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSQPLPPGWTEHKAPSGIPYYWNAELKKSTYQRPSFIEKNHSSSVTASQASLAFNTSEKLFVNENAEERKNSRDLRKQLPDRPKFKKRIPNNDSWVVVFTKKNRYFFHNLKSHESYWEPPLEISKDLKILRLPIRKQISKDSSQSQNVDSGKTNHEEIHESRHLQTEIEEPSGLEESSEESVLYSEEFYEKSDEEEDEEKSHSAEELEFGEEDIMYQLQQLDDETVSYDIQEQATNLSTDDARRVFTELLKDKNIGAYQPWELVYPKLLDDDRFYVLDSGERRKEVFEEYCKSVVSTKKITRRKNTLSDFWTLLHSLPSTLLWPQFKRKYRKSSTLQIPGYSERDFEKLFREFQILRKQPMQDKLLNFKKLCKSKTVDPKNPDEFTESILNDTRYAVLTREELDSLACSSN 7A89C5F7397B8AAF prp22_schpo Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22 SPAC10F6.02c prp22 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MDDLKELEYLSLVSKVASEIRNHTGIDDNTLAEFIINLHDQSKNYDEFKNNVLSCGGEFTDSFLQNISRLIKEIKPKDDIPTDNVNNGSNSVNGASHDLDSKDVDKQHQRKMFPGLSIPNSTNNLRDRPALMDNAMDELEELSTLAKTRRNDRDSRRDERHYLNGIRERRERSISPSFSHHSRTSISGQSHSSRSSRGPLLNAPTLYGIYSGVVSGIKDFGAFVTLDGFRKRTDGLVHISNIQLNGRLDHPSEAVSYGQPVFVKVIRIDESAKRISLSMKEVNQVTGEDLNPDQVSRSTKKGSGANAIPLSAQNSEIGHVNPLETFTSNGRKRLTSPEIWELQQLAASGAISATDIPELNDGFNTNNAAEINPEDDEDVEIELREEEPGFLAGQTKVSLKLSPIKVVKAPDGSLSRAAMQGQILANDRREIRQKEAKLKSEQEMEKQDLSLSWQDTMSNPQDRKFAQDVRDSAARQLTSETPSWRQATRNANISYGKRTTLSMKEQREGLPVFKLRKQFLEAVSKNQILVLLGETGSGKTTQITQYLAEEGYTSDSKMIGCTQPRRVAAMSVAKRVAEEVGCRVGEEVGYTIRFEDKTSRMTQIKYMTDGMLQRECLVDPLLSKYSVIILDEAHERTVATDVLFGLLKGTVLKRPDLKLIVTSATLDAERFSSYFYKCPIFTIPGRSYPVEIMYTKQPEADYLDAALMTVMQIHLSEGPGDILVFLTGQEEIDTSCEILYERSKMLGDSIPELVILPVYSALPSEIQSRIFEPAPPGGRKVVIATNIAETSLTIDGIYYVVDPGFVKQSCFDPKLGMDSLIVTPISQAQARQRSGRAGRTGPGKCYRLYTESAYRNEMLPSPIPEIQRQNLSHTILMLKAMGINDLLNFDFMDPPPAQTMIAALQNLYALSALDDEGLLTPLGRKMADFPMEPQLSKVLITSVELGCSEEMLSIIAMLSVPNIWSRPREKQQEADRQRAQFANPESDHLTLLNVYTTWKMNRCSDNWCYEHYIQARGMRRAEDVRKQLIRLMDRYRHPVVSCGRKRELILRALCSGYFTNVAKRDSHEGCYKTIVENAPVYMHPSGVLFGKAAEWVIYHELIQTSKEYMHTVSTVNPKWLVEVAPTFFKFANANQVSKTKKNLKVLPLYNRFEKPDEWRISKQRKGGR 42503E03FE59E126 prp19_schpo Pre-mRNA-processing factor 19 prp19 Complexed with cdc5 protein 8 cwf8 SPAC29A4.08c RING-type E3 ubiquitin transferase PRP19 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MFCSISGETPKEPVISRVSGNVYEKRLIEQVIRETSKDPVTQQECTLEDLVPVKVPDFVRPRPPSATSLPALLSLFQEEWDSVALEQFELRRNLTETKQELSTALYSLDAALRVISRLTKERDEAREALAKFSDNIGTVSSKTIEVQEVEMGESDDQLKTSLRSTVEKTFQELSSKRKRTKLQPKWATDDAVSQLLQATPSTILENLETESTTSFFPSPENSSFVLCLHKDELLCLDIQSNSTLKIFEGSALACCWLTSSKIAVATADAISIFEFPVSSSGLQSVGEPTSSIPIDEKVNFLQAHPSGEYLLAASNEKCYIFSLKSQVYNITVAQHITSLAVHPDGNLFVAGLENGELRFFETSSGNELTKFGPHSSPVKTLQFGENGYWLVVTTNDDSDIFIWDLRKSELVQKIPLQTKVAAVSLDITSQLLVSSDGETLYVHIYVKSSKSWRCMSQTHVSSISNLVWLNELHQLLFSTSNGAILRLG 3900431C90A94A41 3900431C90A94A41 sf3b1_schpo U2 snRNP component prp10 prp10 sap155 SPAC27F1.09c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSTGTYPYKMFKMDVTNLNKVEDVEIERLRAERELLRRQKEAAKNSSTNGSVNIEGTQDSNDLQYNAHLFKSSNPKEEYDSAIDVRNDISQDEDDYKRTNDVNDSYRLVRQYEAPKELLNEYADESYDPMQERQSKKQIQDRESDYQKQRYDRQLTPTRVDAFQPDGTQSNGRSYAEVMRQVELEKEERRVHMELNQRRREGTLKEVEEEESISDKKRELELNNTEISQKPKRSRWDQAPPSVTQVSTTKRRSRWDKAPENFTISEHVIENGISEDLINKEVNVVEEKLRPPVRLLTEEELNELLPSEGYAILEPPPGYLESIHPELLQKGTTLDTYHVPQEQELPLEKELPAALPTEIPGVGDLAFFKQEDVKYFGKLLKVEDEAKLTIAELRERKILRLLLKVKNGTPPMRKSALRQLTDQARDFGAAALFNQILPLLMERTLEDQERHLLVKVIDRILYKLDDLVRPFTHKILVVIEPLLIDEDYYARAEGREIISNLAKASGLAHMIATMRPDIDHVDEYVRNTTARAFSVVASALGVPALLPFLKAVCRSKKSWQARHTGVRIIQQIALLLGCSILPHLKNLVDCIGHGLEDEQQKVRIMTALSLSALAEAATPYGIEAFDSVLKPLWSGVQRHRGKSLAAFLKATGFIIPLMEPEYASHFTRRIMKILLREFNSPDEEMKKIVLKVVSQCASTDGVTPEYLRTDVLPEFFHCFWSRRMASDRRSYKQVVETTVVLAQQVGSRQIVERVVNNFKDESEPYRKMTAETVDKVIGSLGVSEIDERLEELLLDGVLFAFQEQSVEEKVILTCFSTVVNALGTRCKPYLPQIVSTILYRLNNKSANVREQAADLVSSITIVLKACGEEALMRKLGVVLYEYLGEEYPEVLGSILGAIKAIVSVVGMSSMQPPIRDLLPRLTPILRNRHEKVQENTIDLVGKIADRGSEYVSAREWMRICFELIDMLKAHKKSIRRAAVNTFGYISKAIGPQDVLATLLNNLKVQERQNRVCTTVAIAIVAETCMPFTVVPALMADYRTPEMNVQNGVLKSLAFMFEYIGEQARDYVYAITPLLADALMDRDAVHRQTAASVIKHLSLGCVGLGVEDAMIHLLNILWPNILEESPHVINAVREGIDGIRNCIGVGPIMAYLVQGLFHPSRKVRNTYWTSYNSAYVQSADAMVPYYPHVDDDQFNNYDMKTLHICI BE72C08FEACC8ADF cwc26_schpo Pre-mRNA-splicing factor cwf26 Complexed with cdc5 protein 26 cwf26 SPCC1620.10 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MHSAHMSNADYIAKKYLRKDQGKKKKKKEKDFVEIQDEDVAGWDDDNSFSLVNRELTSLHDAPTIVANESLKDRDIDAIYQNIEKTTNKPAQLWKAVGNDEVVESEQQDSHDAESIPQFGLLTGKQVTFKAEERRKREEKSSNLDEEELRKSRETVYRDATGRRIDLVLARKEAKRKLKEKEEEARRQKEQQQGVVQVRQQKEYLKELERQKTVPLARYEDDPEYNKELKERSRWNDPAASFLTNKPVSSKATYQGYAPPNRFNIRPGHRWDGIIRGNGFENKWFQRQNERKAQEHEAHMWAIEDM 96D266BB3B89BAE6 rse1_schpo Pre-mRNA-splicing factor prp12 Pre-mRNA-processing protein 12 Spliceosome-associated protein 130 prp12 sap130 SPAPJ698.03c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MDTFPSLFLYSLTIQNSNYVQSSCAASLSGKKAQEIVIATESRLLIYKVDATDGRMNCILNQNCFGIIRNVAPLRLTGFKRDYLVVTSDSGRITILEYNVEKNKLVPIYQETFGKSGIRRVVPGEYLAIDAKGRAAMIASVEKNKLVYVLNRDSEANLTISSPLEAHKANNICFHLIGLDTGYANPIFAALEVDYSEIDHDSTREAFTSSEKVLSYYELDLGLNHVVKRWSKVVDRNSYMLIPVPGGNDGPSGTLVISNGWISYRHLQKAFHQIPILRRQAASANAISTPWNQVNSNSANDGPLIVSAVLHKMKGSFFYLLQTGDGDLLKLTIEHDGQGNVVELRLKYFDTVPLAVQLNILKTGFLFVATEFGNHQLYQFENLGIDDDELEITSLDFQAQDNEVGTKNVHFGVRGLQNLSLVEEIPSLYSLTDTLLMKAPSSGEANQLYTVCGRGSNSSLRQLRRGLETTEIVASELPGAPIAIWTLKLNQTDVYDSYIILSFTNGTLVLSIGETVEEISDSGFLSSVSTLNARQMGRDSLVQIHPKGIRYIRANKQTSEWKLPQDVYVVQSAINDMQIVVALSNGELVYFEMSDDVEGGQLNEYQERKTLTANVTSLALGPVQEGSRRSNFMCLACDDATVRVLSLDLYTTLENLSVQALSSPANSLCIIPMNVNGVSTLYLHIGLMNGVYLRTVIDVTSGQLLDTRTRFLGPRAVKIYPITMKNQNTVLAVSSRTFLAYSYQQNLQLSPIAYSAIDHASSFASEQCPEGIVAIQKNTLKIFTVDSLQDDLKSDIYPLICTPRKIVKHPNFPVLYILQSERNFDSFKYAQENGDVGSSYTKEKQNEHTSKSWVSFISVFDMISKKIIHESPLGDNEAAFSMTAAFFKNRDEFFLVAGSATNMDLECRTCSHGNFRVYRFHDEGKKLELISHTEIDGIPMALTPFQGRMLAGVGRFLRIYDLGNKKMLRKGELSAVPLFITHITVQASRIVVADSQYSVRFVVYKPEDNHLLTFADDTIHRWTTTNVLVDYDTLAGGDKFGNIWLLRCPEHVSKLADEENSESKLIHEKPFLNSTPHKLDLMAHFFTNDIPTSLQKVQLVEGAREVLLWTGLLGTVGVFTPFINQEDVRFFQQLEFLLRKECPPLAGRDHLAYRSYYAPVKCVIDGDLCEMYYSLPHPVQEMIANELDRTIAEVSKKIEDFRVRSF 88AC5252ADB7C47D ufd4_yeast Ubiquitin fusion degradation protein 4 UFD4 HECT-type E3 ubiquitin transferase UFD4 YKL162 YKL010C protein protein yeast Saccharomyces cerevisiae Baker's yeast MSENNSHNLDEHESHSENSDYMMDTQVEDDYDEDGHVQGEYSYYPDEDEDEHMLSSVGSFEADDGEDDDNDYHHEDDSGLLYGYHRTQNGSDEDRNEEEDGLERSHDNNEFGSNPLHLPDILETFAQRLEQRRQTSEGLGQHPVGRTLPEILSMIGGRMERSAESSARNERISKLIENTGNASEDPYIAMESLKELSENILMMNQMVVDRIIPMETLIGNIAAILSDKILREELELQMQACRCMYNLFEVCPESISIAVDEHVIPILQGKLVEISYIDLAEQVLETVEYISRVHGRDILKTGQLSIYVQFFDFLTIHAQRKAIAIVSNACSSIRTDDFKTIVEVLPTLKPIFSNATDQPILTRLVNAMYGICGALHGVDKFETLFSLDLIERIVQLVSIQDTPLENKLKCLDILTVLAMSSDVLSRELREKTDIVDMATRSFQHYSKSPNAGLHETLIYVPNSLLISISRFIVVLFPPEDERILSADKYTGNSDRGVISNQEKFDSLVQCLIPILVEIYTNAADFDVRRYVLIALLRVVSCINNSTAKAINDQLIKLIGSILAQKETASNANGTYSSEAGTLLVGGLSLLDLICKKFSELFFPSIKREGIFDLVKDLSVDFNNIDLKEDGNENISLSDEEGDLHSSIEECDEGDEEYDYEFTDMEIPDSVKPKKISIHIFRTLSLAYIKNKGVNLVNRVLSQMNVEQEAITEELHQIEGVVSILENPSTPDKTEEDWKGIWSVLKKCIFHEDFDVSGFEFTSTGLASSITKRITSSTVSHFILAKSFLEVFEDCIDRFLEILQSALTRLENFSIVDCGLHDGGGVSSLAKEIKIKLVYDGDASKDNIGTDLSSTIVSVHCIASFTSLNEFLRHRMVRMRFLNSLIPNLTSSSTEADREEEENCLDHMRKKNFDFFYDNEKVDMESTVFGVIFNTFVRRNRDLKTLWDDTHTIKFCKSLEGNNRESEAAEEANEGKKLRDFYKKREFAQVDTGSSADILTLLDFLHSCGVKSDSFINSKLSAKLARQLDEPLVVASGALPDWSLFLTRRFPFLFPFDTRMLFLQCTSFGYGRLIQLWKNKSKGSKDLRNDEALQQLGRITRRKLRISRKTIFATGLKILSKYGSSPDVLEIEYQEEAGTGLGPTLEFYSVVSKYFARKSLNMWRCNSYSYRSEMDVDTTDDYITTLLFPEPLNPFSNNEKVIELFGYLGTFVARSLLDNRILDFRFSKVFFELLHRMSTPNVTTVPSDVETCLLMIELVDPLLAKSLKYIVANKDDNMTLESLSLTFTVPGNDDIELIPGGCNKSLNSSNVEEYIHGVIDQILGKGIEKQLKAFIEGFSKVFSYERMLILFPDELVDIFGRVEEDWSMATLYTNLNAEHGYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLNPKFTVVLKHAEDGLTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEGAGAFLLS A9B8B9D812C6216F A9B8B9D812C6216F ye8a_schpo Probable inositol polyphosphate 5-phosphatase C9G1.10c SPAC9G1.10c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MASRQGFSNVNEDEPELPPSVLSLKSKFESLSTGDLTNLDEKTAKRRTVKGCKNGTSEPNVFKARPIPPPRQVSSTIGSSTGRKVSGSIQRLASNFKNPSNPHADVSKIDRLPSDSSESHVATPSSPTISNSFVSVSPLLKRPQQKGPEISFQSSVQSTKGNDLMKHDDTNNHQIPPPKPNFSSKAGSSSPISVSPLKNVKAYISQSPTHSEASSVLSSEEEEENVINSSKSVPSFDLHDPFSQTFGKECPISTAPPVLNIGDRSLETPPPIPSPRPPQPVAVEAIQQSRAVISQQLPLHVSPRKPPKPPLRKVSTQRSSSPIENLATKSDASLVTGLQSSPYTHIAPASEMSLIPEKPRLPPRPSHTLSELSSPALTSENLSSKPSPLFPPPPPRVKSLATNKPVSMPVSTEQSDPSVAASSSSSSQLDVVLKGSIPDTSSVRRNPPCFVNGVESINVDFEARIFDVSGDRLVLAGNGGLRVYDTVTGLCHWHMPLGDTKVTSLSFKSSPENYSDDGRFVWFGTRDGMLWEVDVQNHHIVTKKSVSNCPITYVMVYKNEMWTLDDMGKLYVWQEDEIMGLSIQSTPHSIRTIPHATHAMVLDNRLLWVVVGKSIYVYDPSTSENESASVLAKPMTPPGLIGDISCGTTISNFTDLVFYGHVDGKISIFSKTQYRFLELITSSSFYRICSLVGVGNTLWAAYTTGMIYVFDVSESPWRLLKSWHGHKASHNGATTILGIDVNSVWKAKRLQVVSMASSVVKFWDGLMMGDWLATEMRSRFPEYSNFTDVSILICSWNAGASKPSDLDSDTIGASMIPMMIRDNGYPDIVVFGFQELVDLENKRLTARSILSKSSSKGGSSNSANISSQYRLWREKLESEMMRVSSNDDYQVLVCENLVGLFSCVFVKNKLQSKIRMLQSTTVKTGLGGLHGNKGAIVVRFLVDDTSYCIVNCHLAAGQSNKAARNNDLATILDNASLFPENDETDQLNTFVGGGDGSLIMDHEVCVLHGDLNYRINTLRPKALDLIKKNDIKTLLQSDQLLVERKRNAGFRLRTFTEPEITFAPTYKYDVHSEQYDSSEKKRVPAWCDRICYRGSPDYISAENYTRYELKASDHRPVSALIHSKAKMVNAQSQGSTWDVVKRKWIEYADEFKRKAKITYVMNYTSVSYQTAEQYLSGNNWNVQNALKQVSS 7BAB86AD85F3A7E7 ntc20_yeast Pre-mRNA-splicing factor NTC20 YBR188C YBR1316 NTC20 SNT384 PRP19-associated complex protein 20 Synergistic to PRP19 mutation protein 384 protein protein yeast Saccharomyces cerevisiae Baker's yeast MPSLRDLSLERDQELNQLRARINQLGKTGKEEANDFVGLNISNEPVYDTVIQTGQSSNATNSFVQETIQKTKQKESGQPYIIPQKNEHQRYIDKVCETSDLKAKLAPIMEVLEKKTNEKIKGIIRKRVLQEPDRDNDDSG 15C5234B25213223 15C5234B25213223 prp19_yeast Pre-mRNA-processing factor 19 PRP19 PSO4 RING-type E3 ubiquitin transferase PRP19 YLL036C protein protein yeast Saccharomyces cerevisiae Baker's yeast MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEIVPSAQQASLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAAKLVAAQLLMEKNEDSKDLPKSSQQAVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNLELLQAQNYSRNIKTFPYKELNKSMYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPRTGGEHPAIISRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVVCGDGGIAAILKTNDSFNIVALTP A44D8C7DD6F64185 A44D8C7DD6F64185 rsmb_schpo Small nuclear ribonucleoprotein-associated protein B SPAC26A3.08 smb1 Sm protein B protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MGTTKMVSLLNHSLNVTTKDGRTFVGQLLAFDGFMNLVLSDCQEYRHIKKQNVPSNSVYEEKRMLGLVILRGEFIVSLSVQGPPPMDPSMRGSLLSGPGVARPAGRGIPLGQAPVGLAGPVRGVGYTAPPPPAGFGRGAPPPGFRPV 09FD4F2D583F0FF5 spp42_schpo Pre-mRNA-splicing factor spp42 Complexed with cdc5 protein 6 spp42 cwf6 SPAC4F8.12c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MASLPPGNPPPPPPPPGFEPPSQPPPPPPPGYVKKRKNKTPAQSGNLEKQLNERARKWRASQKSKFGVKRKQGYVQTEKADLPPEHLRKIMKDRGDMSSRKFRADKRSYLGALKYLPHAVLKLLENMPMPWEEYREVKVLYHVTGAITFVNESPRVIEPHFIAQWGTMWMMMRREKRDRKNFKRLRFPPFDDEEPPFSIDQLLDLEPLEAIRMDLDEEDDAPVMDWFYENKALEDTPHVNGPTYRRWKLNLPQMANLHRLGYQLLSDLRDDNYFYLFNDNSFFTAKALNVAIPGGPKFEPLYKDEAPEMEDWNEFNDIYKLIIRHPIKTEYRIAFPYLYNSRARSVALSEYHQPSNVFVPPEDPDLPAFFWDPIINPITSRQLTLHELDTSPEDSAIEEDPNFEIPFDPFFHSEDIEFEHTASALILLWAPHPFNKRSGATKRAQDVPLIKHWYLEHCPPNQPVKVRVSYQKLLKSHVMNKLHMAHPKSHTNRSLLRQLKNTKFFQSTSIDWVEAGLQVCRQGYNMLQLLIHRKGLTYLHLDYNCNLKPTKTLTTKERKKSRFGNAFHLMREILRLTKLIVDSHVQYRLGNIDAYQLADGLHYIFNHVGQLTGMYRYKYRLMRQIRACKDFKHLIYYRFNTGPVGKGPGCGFWAPSWRVWLFFLRGIVPLLERWLGNLLARQFEGRHSTGVAKQITKQRVDSHQDLELRAAVMNDILDMIPEGIRQGKSKTILQHLSEAWRCWKANIPWKVPGLPAPIENMILRYVKSKADWWTSVAHFNRERIRRGATVDKTVAKKNLGRLTRLWLKAEQERQHNYLKDGPYVTADEAVAIYTTFVHWLESRRFQPIPFPPLSYKHDTKLLVLALERLKEAYSVKGRLNQSQREELALVEQAYDNPHEMLSQIKRRLLTMRTFKEVGIEFMDMYSHLIPVYSVDPMEKICDAYLDQYLWFEADRRHLFPSWVKPSDSEPPPLLVYKWCQGINNLTDVWETSNGECNVLMETRLSKVFEKVDLTLLNRLMSLLMDTNLASYASAKNNVVLSYKDMSHTNSYGLVRGLQFSSFIWQFYGLVLDLLILGLQRATEIAGPADAPNDFLHFKDQATETSHPIRLYTRYIDKVYIMFRFTDEESRDLIQRFLNENPDPTNSNVVNYSKGKKNCWPRDARMRLMKHDVNLGRAVFWEIRNRLPRSLTTLEWEDTFPSVYSKDNPNLLFSMTGFEVRILPKIRQNEEFSLKDGVWNLTDNRTKQRTAQAFIRVTEDGINQFGNRIRQILMSSGSTTFTKIANKWNTALIALMTYYREAAISTPELLDLLVKCESKIQTRVKISLNSKMPSRFPPAVFYSPKELGGLGMLSMGHVLIPQSDLRWSKQTDTGITHFRSGMTTNGEHLIPNLYRYIQPWESEFIDSQRVWAEYAMKRQEALQQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTEFKQYQLLKNNPFWWTSQRHDGKLWQLNNYRVDVIQALGGVEGILEHTMFKATGFPSWEGLFWEKASGFEESMKFKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIMMHGKIPTLKISLIQIFRSHLWQKIHESVVWDLCQVLDQELESLQIETVQKETIHPRKSYKMNSSCADILLLAAYKWNVSRPSLLNDNRDVLDNTTTNKYWIDVQLRFGDYDSHDIERYTRAKFLDYSTDAQSMYPSPTGVLIGIDLCYNMHSAYGNWIPGMKPLIQQSMNKIMKANPALYVLRERIRKGLQLYASEPQEQYLSSSNYAELFSNQIQLFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKVIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPRQIIVTRKGMLDPLEVHLLDFPNITIKGSELQLPFQAIIKLDKINDLILRATEPQMVLFNLYDDWLQSVSSYTAFSRLILILRALNVNTEKTKLILRPDKSIITKENHVWPNLDDQQWLDVEPKLRDLILADYAKKNNINVASLTNSEVRDIILGMTITAPSLQRQQIAEIEKQGRENAQVTAVTTKTTNVHGDEMVVTTTSAYENEKFSSKTEWRNRAISSISLPLRTKNIYVNSDNISETFPYTYILPQNLLRKFVTISDLRTQVAGYMYGKSPSDNPQIKEIRCIALVPQLGSIRNVQLPSKLPHDLQPSILEDLEPLGWIHTQSSELPYLSSVDVTTHAKILSSHPEWDTKAVTLTVSYIPGSISLAAYTVSKEGIEWGSKNMDINSDEAIGYEPSMAEKCQLLLSDRIQGFFLVPEEGVWNYNFNGASFSPKMTYSLKLDVPLPFFALEHRPTHVISYTELETNDRLEEDMPDAFA 128DB6CF3B22EC29 isy1_schpo Pre-mRNA-splicing factor cwf12 Complexed with cdc5 protein 12 cwf12 isy1 SPBC32F12.05c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSSAKYVVGSKPTEKRPKDIKSIKSVPICEKHRASVVKDISRKISRIQSATLPEYQIRDLNDAINRLMREKHEWEVQIRDLGGINYLYNKAKLFEDEGEQISDIDDYRYYGRARELPGVKELFEADMSFIPERQRKQEMQKRRLDAWYFGYIPPAQESLLEDFEAKIEEQQHKHLENLGDEVEQDWKPLVIEQIPTRDDVEAILLERRKNALLSRIS 6E829D95858F3A85 sf3b1_yeast U2 snRNP component HSH155 YMR288W YM8021.14 HSH155 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSHPIQFVNANNSDKSHQLGGQYSIPQDLRENLQKEAARIGENEKDVLQEKMETRTVQNREDSYHKRRFDMKFEPDSDTQTVTSSENTQDAVVPRKRKSRWDVKGYEPPDESSTAVKENSDSALVNVEGIHDLMFFKPSDHKYFADVISKKPIDELNKDEKKERTLSMLLLKIKNGNTASRRTSMRILTDKAVTFGPEMIFNRLLPILLDRSLEDQERHLMIKTIDRVLYQLGDLTKPYVHKILVVAAPLLIDEDPMVRSTGQEIITNLSTVAGLKTILTVMRPDIENEDEYVRNVTSRAAAVVAKALGVNQLLPFINAACHSRKSWKARHTGIKIVQQIGILLGIGVLNHLTGLMSCIKDCLMDDHVPVRIVTAHTLSTLAENSYPYGIEVFNVVLEPLWKGIRSHRGKVLSSFLKAVGSMIPLMDPEYAGYYTTEAMRIIRREFDSPDDEMKKTILLVLQKCSAVESITPKFLREEIAPEFFQKFWVRRVALDRPLNKVVTYTTVTLAKKLGCSYTIDKLLTPLRDEAEPFRTMAVHAVTRTVNLLGTADLDERLETRLIDALLIAFQEQTNSDSIIFKGFGAVTVSLDIRMKPFLAPIVSTILNHLKHKTPLVRQHAADLCAILIPVIKNCHEFEMLNKLNIILYESLGEVYPEVLGSIINAMYCITSVMDLDKLQPPINQILPTLTPILRNKHRKVEVNTIKFVGLIGKLAPTYAPPKEWMRICFELLELLKSTNKEIRRSANATFGFIAEAIGPHDVLVALLNNLKVQERQLRVCTAVAIGIVAKVCGPYNVLPVIMNEYTTPETNVQNGVLKAMSFMFEYIGNMSKDYIYFITPLLEDALTDRDLVHRQTASNVITHLALNCSGTGHEDAFIHLMNLLIPNIFETSPHAIMRILEGLEALSQALGPGLFMNYIWAGLFHPAKNVRKAFWRVYNNMYVMYQDAMVPFYPVTPDNNEEYIEELDLVL 27D26E4252A788E2 27D26E4252A788E2 ruxf_schpo Small nuclear ribonucleoprotein F smf1 SPBC3E7.14 SPBC4F6.01 Sm protein F protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSFVPVNPKPFLQGLIGKPVLVRLKWGQEYKGTLQSVDSYMNLQLLNAEELVDGVKTGDLGEILIRCNNVLWVGESTV 005687FA91F013CA sn114_yeast Pre-mRNA-splicing factor SNU114 GIN10 YKL173W YKL637 SNU114 Growth inhibitory protein 10 114 kDa U5 small nuclear ribonucleoprotein component protein protein yeast Saccharomyces cerevisiae Baker's yeast MEGDDLFDEFGNLIGVDPFDSDEEESVLDEQEQYQTNTFEGSGNNNEIESRQLTSLGSKKELGISLEHPYGKEVEVLMETKNTQSPQTPLVEPVTERTKLQEHTIFTQLKKNIPKTRYNRDYMLSMANIPERIINVGVIGPLHSGKTSLMDLLVIDSHKRIPDMSKNVELGWKPLRYLDNLKQEIDRGLSIKLNGSTLLCTDLESKSRMINFLDAPGHVNFMDETAVALAASDLVLIVIDVVEGVTFVVEQLIKQSIKNNVAMCFVINKLDRLILDLKLPPMDAYLKLNHIIANINSFTKGNVFSPIDNNIIFASTKLGFTFTIKEFVSYYYAHSIPSSKIDDFTTRLWGSVYYHKGNFRTKPFENVEKYPTFVEFILIPLYKIFSYALSMEKDKLKNLLRSNFRVNLSQEALQYDPQPFLKHVLQLIFRQQTGLVDAITRCYQPFELFDNKTAHLSIPGKSTPEGTLWAHVLKTVDYGGAEWSLVRIYSGLLKRGDTVRILDTSQSESRQKRQLHDISKTETSNEDEDEDDETPSCEVEEIGLLGGRYVYPVHEAHKGQIVLIKGISSAYIKSATLYSVKSKEDMKQLKFFKPLDYITEAVFKIVLQPLLPRELPKLLDALNKISKYYPGVIIKVEESGEHVILGNGELYMDCLLYDLRASYAKIEIKISDPLTVFSESCSNESFASIPVSNSISRLGEENLPGLSISVAAEPMDSKMIQDLSRNTLGKGQNCLDIDGIMDNPRKLSKILRTEYGWDSLASRNVWSFYNGNVLINDTLPDEISPELLSKYKEQIIQGFYWAVKEGPLAEEPIYGVQYKLLSISVPSDVNIDVMKSQIIPLMKKACYVGLLTAIPILLEPIYEVDITVHAPLLPIVEELMKKRRGSRIYKTIKVAGTPLLEVRGQVPVIESAGFETDLRLSTNGLGMCQLYFWHKIWRKVPGDVLDKDAFIPKLKPAPINSLSRDFVMKTRRRKGISTGGFMSNDGPTLEKYISAELYAQLRENGLVP 5CE30CEFF154D013 5CE30CEFF154D013 snu23_schpo U4/U6.U5 small nuclear ribonucleoprotein component snu23 snu23 SPAC22F3.11c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MDRYNPPRRNGNSKKNEVVITGGRTQRIDFEKDVNKTTILPAGASVGRRGRGAGWYCEACNETYKDSLSWLDHLNSTQHLRKTRTVIIEKRATLEEVKERMEYWRRQLLEPEKGSEEYSLKERVERYHQELEAKKLRRKQKKVNKEKNSPRLVGENTELAAIMGISSFGSTNL DD7490AFDC72E06D cwc2_yeast Pre-mRNA-splicing factor CWC2 CWC2 YDL209C D1041 NTC40 SLC3 Complexed with CEF1 protein 2 PRP19-associated complex protein 40 Synthetic lethal with CLF1 protein 3 protein protein yeast Saccharomyces cerevisiae Baker's yeast MTSWRDKSAKVQVKESELPSSIPAQTGLTFNIWYNKWSQGFAGNTRFVSPFALQPQLHSGKTRGDNDGQLFFCLFFAKGMCCLGPKCEYLHHIPDEEDIGKLALRTEVLDCFGREKFADYREDMGGIGSFRKKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYVESKNCGFVKFKYQANAEFAKEAMSNQTLLLPSDKEWDDRREGTGLLVKWANEDPDPAAQKRLQEELKLESLNMMVHLINNNTNSAGTEVNNKNNERLDRTFPEASVDNVKKRLLPLDNGMESDDFIEKLKKVKKNISRENISSKPSVGKLGGPLLDYLSSDED 371734A11DFDB339 371734A11DFDB339 cef1_schpo Pre-mRNA-splicing factor cdc5 Cell division control protein 5 SPAC644.12 cdc5 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MVVLKGGAWKNTEDEILKAAVSKYGKNQWARISSLLVRKTPKQCKARWYEWIDPSIKKTEWSREEDEKLLHLAKLLPTQWRTIAPIVGRTATQCLERYQKLLDDLEAKENEQLGLISGEGAEAAAPVNDPNSRLRFGEAEPNLETLPALPDAIDMDEDEKEMLSEARARLANTQGKKAKRKDREKQLELTRRLSHLQKRRELKAAGINIKLFRRKKNEMDYNASIPFEKKPAIGFYDTSEEDRQNFREKREADQKIIENGIRNNEMESEGRKFGHFEKPKPIDRVKKPNKDAQEEKMRRLAEAEQMSKRRKLNLPSPTVSQDELDKVVKLGFAGDRARAMTDTTPDANYSTNLLGKYTQIERATPLRTPISGELEGREDSVTIEVRNQLMRNREQSSLLGQESIPLQPGGTGYTGVTPSHAANGSALAAPQATPFRTPRDTFSINAAAERAGRLASERENKIRLKALRELLAKLPKPKNDYELMEPRFADETDVEATVGVLEEDATDRERRIQERIAEKERLAKARRSQVIQRDLIRPSVTQPEKWKRSLENEDPTANVLLKEMIALISSDAINYPFGNSKVKGTANKVPDLSNEEIERCRLLLKKEIGQLESDDYIQFEKEFLETYSALHNTSSLLPGLVIYEEDDEDVEAAEKFYTNDIQRDLAKKALECNKLENRVYDLVRSSYEQRNFLIKKISHAWKALQTERKNLTCYEFLYNQERLALPNRLEAAEIELSKMQQIEAYAQQDYARVTGQN 9FCA639A2F9A9E84 9FCA639A2F9A9E84 syf1_schpo Pre-mRNA-splicing factor cwf3 Complexed with cdc5 protein 3 cwf3 syf1 SPBC211.02c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MGDVIPLKVNFDLINVDDEPFELELLRDPYSLKSWLRYIKTHEGSTLEKRVLLFERACSELPGSYKIWKSYLELRVAHVEHLNPYFHAEAFASVNDCFERSLILLHKMPVIWKLYLQFLMKQPNVTKIRCTFNSALRALPVTQHDDIWDMFTKYAEDIGGLFCIHVYRRYIQVEPRAIENYIEILCKLGLWNEAARQYEDILNRPVFLSAKRKSNYQIWLEFSELVVQHPDHTQNIDVEKVFRAGIKRFSDQAGKLWTYLAQYYIRIGDYEKARSTFYEGMNNIMTVRNFTIIFDAFVEFEEQWLSARVEASSGNANDELSIDFHMAWLEKILDKRPLYINDVLLRQNINNVDEWLRRVKFLEDDSEKVVQVYTDAIKNVNPKLAHGSLGKLFSEFARFYENFDDLEQSRIIFEKATHVPYKTVNELAQVWIDWAEMELRHQNFDAARKLIGDAVHAPRKSHISFFDESLSPQVRLHKSSKIWMYYLDLEESVGTIETTRKLYDRVFELKIATPQVVVNYANLLEENAYFEDSFKIYERGVALFSYPVAFELWNLYLTKFVKRYQGTHMERTRDLFEQALEGCPPEFSKSIYLLYADFEEKFGKAKRSISILEKAADKVKTADRLAIYNVLLVKVALNYGVLATRTVYEKAIESLSDSEVKDMCLRFAEMETKLGEIDRARLIYIHGSQYCDPRVETDYWKAWQEFEIRYGNPEETVKEMLRIKRSVQTKFSTDSLHIAKRAAKIESAAAPMDPMEQLEMEKSEGPKALAGFVLSKSNPQETSKITGEEN 4915D160DD83F324 sn309_yeast Pre-mRNA-splicing factor SNT309 YPR101W SNT309 NTC25 Synergistic to PRP19 mutation protein 309 PRP19-associated complex protein 25 protein protein yeast Saccharomyces cerevisiae Baker's yeast MDGLSFVDKGKIPDGYKNEIDQLVKKEFANIKREPVHPEIRGILAKRKGADNSVSTLTNALYTEYLKQRNNKKRRTPDFNDDDDTLFLEEYRRKYPRIDTSRYIPNESSEVSLLGIVDSYLKHQEIVLDTLLPQTVSNQWRINNDYIRQTCTIVEEMNIQQRKQINDLEIYRKRL B781CA65BC9A1918 B781CA65BC9A1918 prp17_schpo Pre-mRNA-processing factor 17 prp17 SPBC6B1.10 protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MLVANYSSDSEEQENSQSPNIQPLLHTENLAPAVVDNVKDDLIVSKGGNSRELARNVPVNEMVQPALGPANPFVTKEQDSIKNSITGYAEREYVPNFVFNQEYYANTHAIYGKRNFDDNEATTSTDLKRKSQKIKERREDPGDPSILEGDGAYKGPWAGYGSEQSSSPLEYSEYEEVESLDVKSEKDTESNNLGQNELLKEQLATPEVETHRSKEETILHKDRLFDYQNRSYMHVPNDVGINLSEEPGEQTCYIPKKHIFTWKGHTKGISCLRFFPISGHLLLSGSMDNQIKIWEVYHDRSLLRTFQGHARPIRDLSFSQDGRSFLSTSFDKTIKLWDTELGKCLNCFNSDRLTNCVKFQVDPDKPNEFLAGTADKRILQFDIRSPDIVQAYDHHLGGINSITFLENGKRFVTTSDDSSMRFWEYGTPVPIKFVADIAMHSMPRVALRPNGKSIACQSLDNCIYVYSAYEKYRQNKKKVFKGYSCSGYSLEVGFSPDGRFVFSGDSSGNACFWDWKTCKLMAKLPAHSGPVQSMAFHPQETSKVATSSIVDGSIKYWD 78859607D4460195 cwf18_schpo Pre-mRNA-splicing factor cwf18 cwf18 Complexed with cdc5 protein 18 SPCP1E11.07c protein protein schpo Schizosaccharomyces pombe (strain ATCC 38366 / 972) Fission yeast MSSLDEVAESRKQRLAELRKIKQLENKTRDSQEVQKNVIEHRNYDPEVQAPKMGFVEPPNMIESVEALSKEIEEKTKRKIEEQSSVPVEELDLVTLRPKKPTWDLERDLKERMRSLETQNQNAIAFYIQQLISERAHSTEKA E66F4815B8C9175A prp19-cwc2 4 94 unspecified role unspecified role prey prey 86 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Fig. 1B prp19-cdc40 4 86 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 33 unspecified role unspecified role prey prey physical association physical association Fig. 1B prp19-urn1-1 4 46 unspecified role unspecified role prey prey 86 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Fig. 1B prp19-mih1 4 86 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 14 unspecified role unspecified role prey prey physical association physical association Fig. 1B prp19-yo314 4 86 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 49 unspecified role unspecified role prey prey physical association physical association Fig. 1B prp19-uba3 4 86 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 22 unspecified role unspecified role prey prey physical association physical association Fig. 1B prp19-yp257 4 67 unspecified role unspecified role prey prey 86 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Fig. 1B prp19-ufd4 4 83 unspecified role unspecified role prey prey 86 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Fig. 1B prp19-cdc40-1 5 33 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) 86 unspecified role unspecified role bait bait purified purified region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) direct interaction direct interaction Fig. 1C prp19-cwc2-1 5 94 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 86 unspecified role unspecified role bait bait purified purified region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined direct interaction direct interaction Fig. 1C prp19-urn1-2 5 46 unspecified role unspecified role prey prey purified purified region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) 86 unspecified role unspecified role bait bait purified purified region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) direct interaction direct interaction Fig. 1C cwf8-prp17 8 79 unspecified role unspecified role bait bait region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 98 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 1D prp17-cwf8 8 79 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 98 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 1D dre4-cwf8 8 79 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 77 unspecified role unspecified role bait bait region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 1D cwf8-dre4 8 79 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 77 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 1D dre4-brr2-1 3 35 unspecified role unspecified role prey prey 79 unspecified role unspecified role prey prey 30 unspecified role unspecified role prey prey 81 unspecified role unspecified role prey prey 20 unspecified role unspecified role prey prey 42 unspecified role unspecified role prey prey 80 unspecified role unspecified role prey prey 88 unspecified role unspecified role prey prey 95 unspecified role unspecified role prey prey 53 unspecified role unspecified role prey prey 16 unspecified role unspecified role prey prey 70 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 26 unspecified role unspecified role prey prey 37 unspecified role unspecified role prey prey 99 unspecified role unspecified role prey prey 48 unspecified role unspecified role prey prey 82 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey 50 unspecified role unspecified role prey prey 72 unspecified role unspecified role prey prey 27 unspecified role unspecified role prey prey 87 unspecified role unspecified role prey prey 73 unspecified role unspecified role prey prey 93 unspecified role unspecified role prey prey 43 unspecified role unspecified role prey prey 32 unspecified role unspecified role prey prey 17 unspecified role unspecified role prey prey 59 unspecified role unspecified role prey prey 74 unspecified role unspecified role prey prey 77 unspecified role unspecified role prey prey 36 unspecified role unspecified role prey prey 77 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 38 unspecified role unspecified role prey prey association association Fig. 3 prp17-alpha_cateni-1 3 98 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 50 unspecified role unspecified role prey prey 37 unspecified role unspecified role prey prey 78 unspecified role unspecified role prey prey 26 unspecified role unspecified role prey prey 44 unspecified role unspecified role prey prey 81 unspecified role unspecified role prey prey 79 unspecified role unspecified role prey prey 62 unspecified role unspecified role prey prey 34 unspecified role unspecified role prey prey 24 unspecified role unspecified role prey prey 87 unspecified role unspecified role prey prey 30 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 45 unspecified role unspecified role prey prey 42 unspecified role unspecified role prey prey 53 unspecified role unspecified role prey prey 88 unspecified role unspecified role prey prey 91 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey 35 unspecified role unspecified role prey prey 89 unspecified role unspecified role prey prey 58 unspecified role unspecified role prey prey 99 unspecified role unspecified role prey prey 39 unspecified role unspecified role prey prey 60 unspecified role unspecified role prey prey 41 unspecified role unspecified role prey prey 72 unspecified role unspecified role prey prey 96 unspecified role unspecified role prey prey 48 unspecified role unspecified role prey prey 95 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 16 unspecified role unspecified role prey prey 70 unspecified role unspecified role prey prey 59 unspecified role unspecified role prey prey 43 unspecified role unspecified role prey prey 38 unspecified role unspecified role prey prey 69 unspecified role unspecified role prey prey 64 unspecified role unspecified role prey prey 28 unspecified role unspecified role prey prey 66 unspecified role unspecified role prey prey association association Fig 3 cwf8-brr2 3 79 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 37 unspecified role unspecified role prey prey 91 unspecified role unspecified role prey prey 39 unspecified role unspecified role prey prey 27 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 89 unspecified role unspecified role prey prey 96 unspecified role unspecified role prey prey 24 unspecified role unspecified role prey prey 70 unspecified role unspecified role prey prey 88 unspecified role unspecified role prey prey 78 unspecified role unspecified role prey prey 58 unspecified role unspecified role prey prey 99 unspecified role unspecified role prey prey 35 unspecified role unspecified role prey prey 16 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey 48 unspecified role unspecified role prey prey 62 unspecified role unspecified role prey prey 34 unspecified role unspecified role prey prey 53 unspecified role unspecified role prey prey 82 unspecified role unspecified role prey prey 45 unspecified role unspecified role prey prey 95 unspecified role unspecified role prey prey 81 unspecified role unspecified role prey prey 30 unspecified role unspecified role prey prey 41 unspecified role unspecified role prey prey 50 unspecified role unspecified role prey prey 98 unspecified role unspecified role prey prey 80 unspecified role unspecified role prey prey 42 unspecified role unspecified role prey prey 26 unspecified role unspecified role prey prey 87 unspecified role unspecified role prey prey 60 unspecified role unspecified role prey prey 44 unspecified role unspecified role prey prey 21 unspecified role unspecified role prey prey 59 unspecified role unspecified role prey prey 73 unspecified role unspecified role prey prey 32 unspecified role unspecified role prey prey 38 unspecified role unspecified role prey prey 84 unspecified role unspecified role prey prey 64 unspecified role unspecified role prey prey 69 unspecified role unspecified role prey prey 40 unspecified role unspecified role prey prey 28 unspecified role unspecified role prey prey 17 unspecified role unspecified role prey prey association association Figure 3 cwf2-brr2 3 87 unspecified role unspecified role prey prey 96 unspecified role unspecified role prey prey 30 unspecified role unspecified role prey prey 45 unspecified role unspecified role prey prey 41 unspecified role unspecified role prey prey 53 unspecified role unspecified role prey prey 34 unspecified role unspecified role prey prey 78 unspecified role unspecified role prey prey 91 unspecified role unspecified role prey prey 89 unspecified role unspecified role prey prey 60 unspecified role unspecified role prey prey 62 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 37 unspecified role unspecified role prey prey 79 unspecified role unspecified role prey prey 48 unspecified role unspecified role prey prey 26 unspecified role unspecified role prey prey 70 unspecified role unspecified role prey prey 39 unspecified role unspecified role prey prey 16 unspecified role unspecified role prey prey 99 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 35 unspecified role unspecified role prey prey 95 unspecified role unspecified role prey prey 98 unspecified role unspecified role prey prey 88 unspecified role unspecified role prey prey 58 unspecified role unspecified role prey prey 42 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role prey prey 38 unspecified role unspecified role prey prey 64 unspecified role unspecified role prey prey 28 unspecified role unspecified role prey prey association association Figure 3 saf1-cdc5-1 3 96 unspecified role unspecified role prey prey 30 unspecified role unspecified role prey prey 79 unspecified role unspecified role prey prey 98 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 88 unspecified role unspecified role prey prey 87 unspecified role unspecified role prey prey 62 unspecified role unspecified role prey prey 16 unspecified role unspecified role prey prey 95 unspecified role unspecified role prey prey 77 unspecified role unspecified role prey prey 75 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Figure 3 yere-cwf10-1 3 31 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 79 unspecified role unspecified role prey prey 81 unspecified role unspecified role prey prey 88 unspecified role unspecified role prey prey 50 unspecified role unspecified role prey prey 72 unspecified role unspecified role prey prey 42 unspecified role unspecified role prey prey 38 unspecified role unspecified role prey prey 43 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Figure 3 ylk3-brr2-1 3 16 unspecified role unspecified role prey prey 72 unspecified role unspecified role prey prey 53 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 88 unspecified role unspecified role prey prey 87 unspecified role unspecified role prey prey 82 unspecified role unspecified role prey prey 42 unspecified role unspecified role prey prey 81 unspecified role unspecified role prey prey 50 unspecified role unspecified role prey prey 27 unspecified role unspecified role prey prey 45 unspecified role unspecified role prey prey 80 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey 70 unspecified role unspecified role prey prey 51 unspecified role unspecified role prey prey 32 unspecified role unspecified role prey prey 93 unspecified role unspecified role prey prey 17 unspecified role unspecified role prey prey 59 unspecified role unspecified role prey prey 12 unspecified role unspecified role prey prey 74 unspecified role unspecified role prey prey 73 unspecified role unspecified role prey prey 68 unspecified role unspecified role prey prey 56 unspecified role unspecified role prey prey 77 unspecified role unspecified role prey prey 76 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Figure 3 cdc40-prp19-1 9 33 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain 86 unspecified role unspecified role prey prey physical association physical association Supp. Fig. 2A prp19-cdc40-3 2 33 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain region mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) 86 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) physical association physical association Fig. 2D prp19-urn1-3 2 46 unspecified role unspecified role prey prey purified purified region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) 86 unspecified role unspecified role bait bait purified purified region his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) physical association physical association Fig. 2D cwf7-cwf8 8 26 unspecified role unspecified role bait bait region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 98 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 79 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Fig. 2E prp17-1 1 33 unspecified role unspecified role neutral component neutral component region mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined direct interaction direct interaction Fig 2G cwf7-cwf2 8 42 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 26 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 98 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Fig. 2H urn1-prp19 9 86 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 46 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Fig. 4A prp19-1 1 86 unspecified role unspecified role neutral component neutral component purified purified direct interaction direct interaction Fig. 4B prp19-urn1-5 6 86 unspecified role unspecified role neutral component neutral component purified purified ecoli Escherichia coli (strain K12) 46 unspecified role unspecified role neutral component neutral component purified purified region his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) direct interaction direct interaction Fig. 4D, 4E, Table 1 cwf8-cwf2 8 42 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 79 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 77 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Fig. 5C cwf8-dre4-1 8 98 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 79 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 77 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Fig. 5D cwf8-cdc5 8 95 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 79 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 77 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Fig. 5E urn1-aim4-1 7 57 unspecified role unspecified role prey prey 52 unspecified role unspecified role prey prey 86 unspecified role unspecified role prey prey 15 unspecified role unspecified role prey prey 61 unspecified role unspecified role prey prey 54 unspecified role unspecified role prey prey 63 unspecified role unspecified role prey prey 97 unspecified role unspecified role prey prey 18 unspecified role unspecified role prey prey 29 unspecified role unspecified role prey prey 92 unspecified role unspecified role prey prey 65 unspecified role unspecified role prey prey 19 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey 71 unspecified role unspecified role prey prey 90 unspecified role unspecified role prey prey 47 unspecified role unspecified role prey prey 55 unspecified role unspecified role prey prey 46 unspecified role unspecified role bait bait region tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Fig. 6 aim4-brr2 7 71 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 63 unspecified role unspecified role prey prey 47 unspecified role unspecified role prey prey 46 unspecified role unspecified role prey prey 61 unspecified role unspecified role prey prey 18 unspecified role unspecified role prey prey 97 unspecified role unspecified role prey prey 52 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey 86 unspecified role unspecified role prey prey 85 unspecified role unspecified role prey prey association association Table 6 dre4-saf1 8 75 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 77 unspecified role unspecified role bait bait region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 7A saf1-dre4 8 75 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 77 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 7A cwf8-saf1 8 79 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 75 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 7B saf1-cwf8 8 79 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 75 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 7B saf1-dre4-1 9 75 unspecified role unspecified role bait bait 77 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Fig. 7C urn1-aim4-2 10 46 unspecified role unspecified role bait bait region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 71 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 7E ylk3-cwf8 8 79 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 76 unspecified role unspecified role bait bait region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Supp. Fig. 3 cwf8-ylk3 8 79 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 76 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Supp. Fig. 3 cwf8-yere 8 79 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 43 unspecified role unspecified role prey prey region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Supp. Fig. 3 yere-cwf8 8 79 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 43 unspecified role unspecified role bait bait region tap tagged calmodulin binding peptide plus protein a tag CBP-ProtA tagged CBP-ProtA tagged tap tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Supp. Fig. 3 dre4-ylk3 8 77 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 76 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Supp. Fig. 3 ylk3-dre4 8 76 unspecified role unspecified role bait bait region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 77 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Supp. Fig. 3 yere-dre4 8 77 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 43 unspecified role unspecified role bait bait region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Supp. Fig. 3 dre4-yere 8 43 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 77 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Supp. Fig. 3 aim4-urn1 10 71 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 46 unspecified role unspecified role prey prey region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 7E