InnateDB InnateDB IL-35-mediated induction of a potent regulatory T cell population. IL-35-mediated induction of a potent regulatory T cell population. Nat. Immunol. (1529-2908) 2010 imex curation Collison LW., Chaturvedi V., Henderson AL., Giacomin PR., Guy C., Bankoti J., Finkelstein D., Forbes K., Workman CJ., Brown SA., Rehg JE., Jones ML., Ni HT., Artis D., Turk MJ., Vignali DA. Fig. 6G. used CD4+ T cells from the spleen and tumor in Foxp3(gfp) mice. vignali.lab@stjude.org jyoti Only protein-protein interactions Curated by: InnateDB - a knowledge resource for innate immunity mouse-t-cell Mouse T cell t-cell Peripheral blood T-lymphocytes anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Collison LW., Chaturvedi V., Henderson AL., Giacomin PR., Guy C., Bankoti J., Finkelstein D., Forbes K., Workman CJ., Brown SA., Rehg JE., Jones ML., Ni HT., Artis D., Turk MJ., Vignali DA. Fig. 6G. used CD4+ T cells from the spleen and tumor in Foxp3(gfp) mice. vignali.lab@stjude.org Accepted 2011-APR-05 by ORCHARD Nat. Immunol. (1529-2908) 2010 jyoti Only protein-protein interactions imex curation Curated by: InnateDB - a knowledge resource for innate immunity il27b_mouse Interleukin-27 subunit beta Ebi3 Epstein-Barr virus-induced gene 3 protein homolog Il27b protein protein mouse Mus musculus Mouse MSKLLFLSLALWASRSPGYTETALVALSQPRVQCHASRYPVAVDCSWTPLQAPNSTRSTSFIATYRLGVATQQQSQPCLQRSPQASRCTIPDVHLFSTVPYMLNVTAVHPGGASSSLLAFVAERIIKPDPPEGVRLRTAGQRLQVLWHPPASWPFPDIFSLKYRLRYRRRGASHFRQVGPIEATTFTLRNSKPHAKYCIQVSAQDLTDYGKPSDWSLPGQVESAPHKP DIP protein O35228 original sequence version: 99 il12a_mouse Interleukin-12 subunit alpha Il12a Cytotoxic lymphocyte maturation factor 35 kDa subunit IL-12 subunit p35 protein protein mouse Mus musculus Mouse MCQSRYLLFLATLALLNHLSLARVIPVSGPARCLSQSRNLLKTTDDMVKTAREKLKHYSCTAEDIDHEDITRDQTSTLKTCLPLELHKNESCLATRETSSTTRGSCLPPQKTSLMMTLCLGSIYEDLKMYQTEFQAINAALQNHNHQQIILDKGMLVAIDELMQSLNHNGETLRQKPPVGEADPYRVKMKLCILLHAFSTRVVTINRVMGYLSSA DIP protein P43431 original sequence version: 99 56845B9B66D35A53 il12a-il27b 1 2 unspecified role unspecified role prey prey 3 unspecified role unspecified role bait bait physical association physical association Fig. 2B, 5C, 6G IL-35 IL-35 interaction not detected in Foxp3-/- splenic T cells, however, the interaction was present in Foxp3-/- tumour cells