MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation. Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation. Cell Death Differ. (1350-9047) 2010 rapid curation Xiao L., Gong LL., Yuan D., Deng M., Zeng XM., Chen LL., Zhang L., Yan Q., Liu JP., Hu XH., Sun SM., Liu J., Ma HL., Zheng CB., Fu H., Chen PC., Zhao JQ., Xie SS., Zou LJ., Xiao YM., Liu WB., Zhang J., Liu Y., Li DW. 30-Sept-2013: Contacted by IntAct-Help. partial coverage rapid curation human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Xiao L., Gong LL., Yuan D., Deng M., Zeng XM., Chen LL., Zhang L., Yan Q., Liu JP., Hu XH., Sun SM., Liu J., Ma HL., Zheng CB., Fu H., Chen PC., Zhao JQ., Xie SS., Zou LJ., Xiao YM., Liu WB., Zhang J., Liu Y., Li DW. Accepted 2013-SEP-06 by MARTA 30-Sept-2013: Contacted by IntAct-Help. Cell Death Differ. (1350-9047) 2010 partial coverage rapid curation rapid curation Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation. Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation. Cell Death Differ. (1350-9047) 2010 rapid curation Xiao L., Gong LL., Yuan D., Deng M., Zeng XM., Chen LL., Zhang L., Yan Q., Liu JP., Hu XH., Sun SM., Liu J., Ma HL., Zheng CB., Fu H., Chen PC., Zhao JQ., Xie SS., Zou LJ., Xiao YM., Liu WB., Zhang J., Liu Y., Li DW. 30-Sept-2013: Contacted by IntAct-Help. partial coverage rapid curation human Homo sapiens Human fluorescence imaging fluorescence microscopy fluorescence imaging predetermined predetermined participant predetermined Xiao L., Gong LL., Yuan D., Deng M., Zeng XM., Chen LL., Zhang L., Yan Q., Liu JP., Hu XH., Sun SM., Liu J., Ma HL., Zheng CB., Fu H., Chen PC., Zhao JQ., Xie SS., Zou LJ., Xiao YM., Liu WB., Zhang J., Liu Y., Li DW. Accepted 2013-SEP-06 by MARTA 30-Sept-2013: Contacted by IntAct-Help. Cell Death Differ. (1350-9047) 2010 partial coverage rapid curation rapid curation Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation. Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation. Cell Death Differ. (1350-9047) 2010 rapid curation Xiao L., Gong LL., Yuan D., Deng M., Zeng XM., Chen LL., Zhang L., Yan Q., Liu JP., Hu XH., Sun SM., Liu J., Ma HL., Zheng CB., Fu H., Chen PC., Zhao JQ., Xie SS., Zou LJ., Xiao YM., Liu WB., Zhang J., Liu Y., Li DW. 30-Sept-2013: Contacted by IntAct-Help. partial coverage rapid curation in vitro In vitro phosphatase assay phosphatase assay predetermined predetermined participant predetermined Xiao L., Gong LL., Yuan D., Deng M., Zeng XM., Chen LL., Zhang L., Yan Q., Liu JP., Hu XH., Sun SM., Liu J., Ma HL., Zheng CB., Fu H., Chen PC., Zhao JQ., Xie SS., Zou LJ., Xiao YM., Liu WB., Zhang J., Liu Y., Li DW. Accepted 2013-SEP-06 by MARTA 30-Sept-2013: Contacted by IntAct-Help. Cell Death Differ. (1350-9047) 2010 partial coverage rapid curation rapid curation akt1_human RAC-alpha serine/threonine-protein kinase AKT1 PKB RAC RAC-PK-alpha Protein kinase B Proto-oncogene c-Akt Protein kinase B alpha protein protein human Homo sapiens Human MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA DIP protein P31749 original sequence version: 184 DIP protein P31749 original sequence version: 168 DIP protein P31749 original sequence version: 102 DIP protein P31749 original sequence version: 110 DIP protein P31749 original sequence version: 160 DIP protein P31749 original sequence version: 136 DIP protein P31749 original sequence version: 175 DIP protein P31749 original sequence version: 201 DIP protein P31749 original sequence version: 166 DIP protein P31749 original sequence version: 178 DIP protein P31749-1 original sequence version: 194 DIP protein P31749 original sequence version: 106 DIP protein P31749 original sequence version: 141 6EAFF4F8AD436714 pp1a_human Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PPP1CA PPP1A protein protein human Homo sapiens Human MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK DIP protein P62136 original sequence version: 72 DIP protein P62136 original sequence version: 76 DIP protein P62136 original sequence version: 123 DIP protein P62136 original sequence version: 126 DIP protein P62136-1 original sequence version: 98 60C37E1AD9831DAC akt1-ppp1ca 3 5 enzyme enzyme neutral component neutral component 4 enzyme target enzyme target substrate substrate neutral component neutral component phosphorylated phosres phosphorylated residue PhosRes Phospho Phosphorylation Phosphorylation (O of Serine, Threonine, Tyrosine and Aspartate, N epsilon of Lysine) certain certain sequence position certain certain certain sequence position certain prerequisite-ptm dephosphorylation dephosphorylation reaction dephosphorylation f2c homomint mint ppp1ca-akt1 1 5 unspecified role unspecified role bait bait 4 unspecified role unspecified role prey prey physical association physical association homomint mint f3a f3b akt1-ppp1ca-1 1 5 unspecified role unspecified role prey prey 4 unspecified role unspecified role bait bait physical association physical association homomint mint f3a f3b akt1-ppp1ca-2 2 5 unspecified role unspecified role unspecified role unspecified role 4 unspecified role unspecified role unspecified role unspecified role colocalization colocalization homomint mint f3f f3j