MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA. p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA. J. Biol. Chem. (0021-9258) 2005 rapid curation Koga Y., Ikebe M. suggested by lperfetto 28-Oct_2013: Contacted by IntAct-Help. yeast Saccharomyces cerevisiae Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Koga Y., Ikebe M. suggested by lperfetto Accepted 2013-OCT-14 by LPERFETTO 28-Oct_2013: Contacted by IntAct-Help. J. Biol. Chem. (0021-9258) 2005 rapid curation p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA. p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA. J. Biol. Chem. (0021-9258) 2005 rapid curation Koga Y., Ikebe M. suggested by lperfetto 28-Oct_2013: Contacted by IntAct-Help. in vitro In vitro phosphatase assay phosphatase assay predetermined predetermined participant predetermined Koga Y., Ikebe M. suggested by lperfetto Accepted 2013-OCT-14 by LPERFETTO 28-Oct_2013: Contacted by IntAct-Help. J. Biol. Chem. (0021-9258) 2005 rapid curation p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA. p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA. J. Biol. Chem. (0021-9258) 2005 rapid curation Koga Y., Ikebe M. suggested by lperfetto 28-Oct_2013: Contacted by IntAct-Help. in vitro In vitro pull down pull down predetermined predetermined participant predetermined Koga Y., Ikebe M. suggested by lperfetto Accepted 2013-OCT-14 by LPERFETTO 28-Oct_2013: Contacted by IntAct-Help. J. Biol. Chem. (0021-9258) 2005 rapid curation p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA. p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA. J. Biol. Chem. (0021-9258) 2005 rapid curation Koga Y., Ikebe M. suggested by lperfetto 28-Oct_2013: Contacted by IntAct-Help. chlae Chlorocebus aethiops Cercopithecus aethiops Grivet Green monkey anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Koga Y., Ikebe M. suggested by lperfetto Accepted 2013-OCT-14 by LPERFETTO 28-Oct_2013: Contacted by IntAct-Help. J. Biol. Chem. (0021-9258) 2005 rapid curation p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA. p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA. J. Biol. Chem. (0021-9258) 2005 rapid curation Koga Y., Ikebe M. suggested by lperfetto 28-Oct_2013: Contacted by IntAct-Help. chlae Chlorocebus aethiops Cercopithecus aethiops Grivet Green monkey anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Koga Y., Ikebe M. suggested by lperfetto Accepted 2013-OCT-14 by LPERFETTO 28-Oct_2013: Contacted by IntAct-Help. J. Biol. Chem. (0021-9258) 2005 rapid curation myl6_human Myosin light polypeptide 6 MYL6 Smooth muscle and nonmuscle myosin light chain alkali 6 Myosin light chain alkali 3 Myosin light chain 3 17 kDa myosin light chain protein protein human Homo sapiens Human MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILSG A2B7B4F41179523D rhoa_human Transforming protein RhoA Rho cDNA clone 12 ARHA RHO12 RHOA ARH12 protein protein human Homo sapiens Human MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLVL DIP protein P61586 original sequence version: 86 DIP protein P61586 original sequence version: 123 DIP protein P61586 original sequence version: 57 DIP protein P61586 original sequence version: 88 DIP protein P61586 original sequence version: 87 DIP protein P61586 original sequence version: 85 DIP protein P61586 original sequence version: 125 DIP protein P61586 original sequence version: 132 C4DA2DC31FF858BC mypt1_rat Protein phosphatase 1 regulatory subunit 12A Ppp1r12a Mbs Mypt1 Myosin phosphatase-targeting subunit 1 Protein phosphatase myosin-binding subunit MBSP Serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110 Protein phosphatase subunit 1M protein protein rat Rattus norvegicus (Rat) Rat MKMADAKQKRNEQLKRWIGSETDLEPPVVKRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMETVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRDKKSPLIESTANMENNQPQKTFKNKETLIIEPEKNASRIESLEQEKADEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPMASVTNAHTASTQAAPAAVTTPTLSSNQGTPTSPVKKFPTSTTKISPKEEERKDESPASWRLGLRKTGSYGALAEITASKEAQKEKDTAGVIRSASSPRLSSSLDNKEKEKDNKGTRLAYVAPTIPRRLGSTSDIEEKENRESSNLRTSSSYTRRKWEDDLKKNSSINEGSTYHRSCSFGRRQDDLISCSVPSTTSTPTVTSAAGLQKSFLSSTSTTAKTPPGSSPAGTQSSTSNRLWAEDSTEKEKDSAPTAATILVAPTVVSAAASSTTALTTTTAGTLSSTSEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKDKEEKEKQDKEKQEEKKESEVSREDEYKQKYSRTYDETYARYRPVSTSSSSTPSSSSLSTLGSSLYASSQLNRPNSLVGITSAYSRGLTKDNEREGEKKEEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQERQSDTEDGSSKRDTQTDSVSRYDSSSTSSSDRYDSLLGRSASYSYLEERKPYGSRLEKDDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQRQERFADRSLLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK 43B9FC1569CD5DDB mypt1_human Protein phosphatase 1 regulatory subunit 12A PPP1R12A MBS MYPT1 Myosin phosphatase-targeting subunit 1 Protein phosphatase myosin-binding subunit protein protein human Homo sapiens Human MKMADAKQKRNEQLKRWIGSETDLEPPVVKRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRDKKSPLIESTANMDNNQSQKTFKNKETLIIEPEKNASRIESLEQEKVDEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQATPTSPIKKFPTTATKISPKEEERKDESPATWRLGLRKTGSYGALAEITASKEGQKEKDTAGVTRSASSPRLSSSLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIEEKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTSTPTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTTTLTTTTAGTVSSTTEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQRQERFADRSLLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK DIP protein O14974 original sequence version: 95 DIP protein O14974 original sequence version: 141 EA43E9BFF5DA08FF pp1b_human Serine/threonine-protein phosphatase PP1-beta catalytic subunit PPP1CB protein protein human Homo sapiens Human MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPPKKR DIP protein P62140 original sequence version: 130 E8356022E9B94ECD mprip_human Myosin phosphatase Rho-interacting protein MRIP Rho-interacting protein 3 p116Rip MPRIP KIAA0864 RHOIP3 protein protein human Homo sapiens Human MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSSSSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSLEKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDASASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTHNVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSVIEQVSWDT 5B7A30CDB3685E4E mprip-ppp1r12a 3 7 unspecified role unspecified role prey prey 11 unspecified role unspecified role bait bait MYPT1 8 unspecified role unspecified role prey prey physical association physical association f1f mint ppp1r12a-mprip 1 MYPT1 8 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey physical association physical association f1a mint ppp1r12a-mprip-1 4 MYPT1 8 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey physical association physical association f1b mint ppp1r12a-mprip-2 5 MYPT1 9 unspecified role unspecified role bait bait 7 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey association association f1c mint mprip-ppp1r12a-1 5 11 unspecified role unspecified role bait bait 7 unspecified role unspecified role prey prey MYPT1 9 unspecified role unspecified role prey prey association association f1c mint myl6-ppp1cb 2 10 enzyme enzyme neutral component neutral component 6 enzyme target enzyme target substrate substrate neutral component neutral component dephosphorylation dephosphorylation reaction dephosphorylation f2a mprip-ppp1r12a-2 3 7 unspecified role unspecified role prey prey 11 unspecified role unspecified role bait bait MYPT1 8 unspecified role unspecified role prey prey physical association physical association f1f mint ppp1r12a-mprip-3 1 MYPT1 8 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey physical association physical association f1a mint ppp1r12a-mprip-4 4 MYPT1 8 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey physical association physical association f1b mint ppp1r12a-mprip-5 5 MYPT1 9 unspecified role unspecified role bait bait 7 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey association association f1c mint