MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin. Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin. FEBS J. (1742-464X) 2010 imex curation Martinho A., Gonçalves I., Cardoso I., Almeida MR., Quintela T., Saraiva MJ., Santos CR. Only protein-protein interactions chlae-cos_7 Cercopithecus aethiops simian cells transformed with SV40 Grivet cos_7 cercopithecus aethiops, by transformation with SV40 anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Martinho A., Gonçalves I., Cardoso I., Almeida MR., Quintela T., Saraiva MJ., Santos CR. FEBS J. (1742-464X) 2010 Only protein-protein interactions imex curation Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin. Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin. FEBS J. (1742-464X) 2010 imex curation Martinho A., Gonçalves I., Cardoso I., Almeida MR., Quintela T., Saraiva MJ., Santos CR. Only protein-protein interactions yeast Saccharomyces cerevisiae Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Martinho A., Gonçalves I., Cardoso I., Almeida MR., Quintela T., Saraiva MJ., Santos CR. FEBS J. (1742-464X) 2010 Only protein-protein interactions imex curation Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin. Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin. FEBS J. (1742-464X) 2010 imex curation Martinho A., Gonçalves I., Cardoso I., Almeida MR., Quintela T., Saraiva MJ., Santos CR. Only protein-protein interactions in vitro In vitro saturation binding saturation binding predetermined predetermined participant predetermined Martinho A., Gonçalves I., Cardoso I., Almeida MR., Quintela T., Saraiva MJ., Santos CR. FEBS J. (1742-464X) 2010 Only protein-protein interactions imex curation Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin. Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin. FEBS J. (1742-464X) 2010 imex curation Martinho A., Gonçalves I., Cardoso I., Almeida MR., Quintela T., Saraiva MJ., Santos CR. Only protein-protein interactions rat-cpec Rattus norvegicus cpec cpec fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Martinho A., Gonçalves I., Cardoso I., Almeida MR., Quintela T., Saraiva MJ., Santos CR. FEBS J. (1742-464X) 2010 Only protein-protein interactions imex curation mt3_human Metallothionein-3 MT3 Metallothionein-III Growth inhibitory factor GIFB protein protein human Homo sapiens Human MDPETCPCPSGGSCTCADSCKCEGCKCTSCKKSCCSCCPAECEKCAKDCVCKGGEAAEAEAEKCSCCQ mint 59801ECF5BC8A406 a4_human Amyloid-beta precursor protein APP A4 AD1 Alzheimer disease amyloid protein ABPP PreA4 Cerebral vascular amyloid peptide Protease nexin-II APPI Amyloid precursor protein Amyloid-beta A4 protein Alzheimer disease amyloid A4 protein homolog Amyloid-beta (A4) precursor protein protein protein human Homo sapiens Human MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN DIP protein P05067 original sequence version: 160 DIP protein P05067 original sequence version: 207 DIP protein P05067 original sequence version: 185 DIP protein P05067 original sequence version: 188 A12EE761403740F5 tthy_human Transthyretin Prealbumin TBPA ATTR TTR PALB protein protein human Homo sapiens Human MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE DIP protein P02766 original sequence version: 114 DIP protein P02766 original sequence version: 163 DIP protein P02766 original sequence version: 174 3A6AEBCBBA56BC44 mt3_rat Metallothionein-3 Mt3 Metallothionein-III Growth inhibitory factor protein protein rat Rattus norvegicus (Rat) Rat MDPETCPCPTGGSCTCSDKCKCKGCKCTNCKKSCCSCCPAGCEKCAKDCVCKGEEGAKAEKCSCCQ BE7538E85664EBF8 tthy_rat Transthyretin Ttr Tt Prealbumin TBPA protein protein rat Rattus norvegicus (Rat) Rat MASLRLFLLCLAGLIFASEAGPGGAGESKCPLMVKVLDAVRGSPAVDVAVKVFKKTADGSWEPFASGKTAESGELHGLTTDEKFTEGVYRVELDTKSYWKALGISPFHEYAEVVFTANDSGHRHYTIAALLSPYSYSTTAVVSNPQN 67F00D09BCF195BA ttr-mt3 2 MT3 5 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell fusion protein fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined TTR 7 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell fusion protein fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association homomint mint no f mt3-ttr 3 MT3 5 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified TTR 7 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified direct interaction direct interaction f1 homomint mint app-ttr 3 Ttr 9 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified Amyloid beta 6 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain physical association physical association f4 homomint mint mt3-ttr-1 4 TTR 9 immunostaining immunostaining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell Mt3 8 immunostaining immunostaining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell colocalization colocalization f2a homomint mint ttr-mt3-1 1 Mt3 5 anti tag western anti tag western blot anti tag western predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Ttr 7 anti tag western anti tag western blot anti tag western predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell myc tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association f3b homomint mint