MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J. (0261-4189) 2010 imex curation Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. Only protein-protein interactions in vitro In vitro comig non denat gel comigration in non denaturing gel electrophoresis comig non denat gel predetermined predetermined participant predetermined Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. EMBO J. (0261-4189) 2010 Only protein-protein interactions imex curation A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J. (0261-4189) 2010 imex curation Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. Only protein-protein interactions in vitro In vitro solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. EMBO J. (0261-4189) 2010 Only protein-protein interactions imex curation A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J. (0261-4189) 2010 imex curation Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. Only protein-protein interactions human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. EMBO J. (0261-4189) 2010 Only protein-protein interactions imex curation A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J. (0261-4189) 2010 imex curation Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. Only protein-protein interactions in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. EMBO J. (0261-4189) 2010 Only protein-protein interactions imex curation A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J. (0261-4189) 2010 imex curation Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. Only protein-protein interactions in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. EMBO J. (0261-4189) 2010 Only protein-protein interactions imex curation A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J. (0261-4189) 2010 imex curation Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. Only protein-protein interactions in vitro In vitro crosslink cross-linking study crosslink predetermined predetermined participant predetermined Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. EMBO J. (0261-4189) 2010 Only protein-protein interactions imex curation A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J. (0261-4189) 2010 imex curation Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. Only protein-protein interactions yeast Saccharomyces cerevisiae Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Giamarchi A., Feng S., Rodat-Despoix L., Xu Y., Bubenshchikova E., Newby LJ., Hao J., Gaudioso C., Crest M., Lupas AN., Honoré E., Williamson MP., Obara T., Ong AC., Delmas P. EMBO J. (0261-4189) 2010 Only protein-protein interactions imex curation pkd2_human Polycystin-2 PKD2 Polycystic kidney disease 2 protein Autosomal dominant polycystic kidney disease type II protein Polycystwin R48321 TRPP2 Transient receptor potential cation channel subfamily P member 2 protein protein human Homo sapiens Human MVNSSRVQPQQPGDAKRPPAPRAPDPGRLMAGCAAVGASLAAPGGLCEQRGLEIEMQRIRQAAARDPPAGAAASPSPPLSSCSRQAWSRDNPGFEAEEEEEEVEGEEGGMVVEMDVEWRPGSRRSAASSAVSSVGARSRGLGGYHGAGHPSGRRRRREDQGPPCPSPVGGGDPLHRHLPLEGQPPRVAWAERLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSTEGMEGAGGNGSSNVHV Functions as a calcium permeable cation channel. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis Defects in PKD2 are the cause of polycystic kidney disease autosomal dominant type 2 (ADPKD2) [MIM:173900]. ADPKD2 represents approximately 15% of the cases of ADPKD, a common genetic disease affecting about 1:400 to 1:1000 individuals. ADPKD is characterized by progressive formation and enlargement of cysts in both kidneys, typically leading to end-stage renal disease in adult life. Cysts also occurs in the liver and other organs. ADPKD2 is clinically milder than ADPKD1 but it has a deleterious impact on overall life expectancy mint F8D2E760EBEA8B47 pkd1_human Polycystin-1 PKD1 Autosomal dominant polycystic kidney disease 1 protein protein protein human Homo sapiens Human MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEYVACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSASFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPVTATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALELVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCYRLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGPAPQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQDAENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELRRPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASCHPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHDAGPGALLHCSPAPGHPGPRAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTVLLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPTNGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALPWLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAGSDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGAAAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATVEHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGNPAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEVGNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGSYLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLWDLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVVPLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSGKGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSAELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQVPVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAGTFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFRLQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCCEPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQVRAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGSPGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVLMRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPRLALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSESYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSLTVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGSKRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGCASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQGHCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGSATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQAETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALMRILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLSDVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNSDWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEPYLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFRWSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSFLTFSGLHAEQAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDYDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSLGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSRGPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST DIP protein P98161 original sequence version: 176 AEDAC48F3F0A853C pkd2-pkd2 7 PC2 8 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell fusion protein fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain CT2 PC2 8 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell Q13563:p.Val846Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain V A Tue Jul 12 10:05:54 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 19:14:31 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val846ala' Tue Jun 30 15:52:32 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val846Ala' Q13563:p.Leu867Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain L A Tue Jul 12 10:49:10 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 19:01:30 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu867ala' Tue Jun 30 16:12:39 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu867Ala' binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain CC2 fusion protein fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Q13563:p.Ile860Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:05:46 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 17:26:24 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860ala' Tue Jun 30 16:57:06 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Ala' Q13563:p.Ile853Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:05:45 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 20:28:58 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile853ala' Tue Jun 30 19:29:41 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile853Ala' physical association physical association f2a homomint mint pkd2-pkd1 7 PC2 8 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell Q13563:p.Ile860Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:09:04 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 15:27:36 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860ala' Tue Jun 30 17:20:49 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Ala' Q13563:p.Leu867Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain L A Tue Jul 12 10:09:03 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 18:46:18 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu867ala' Tue Jun 30 16:41:08 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu867Ala' fusion protein fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Q13563:p.Ile853Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:50:01 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 19:04:01 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile853ala' Tue Jun 30 18:37:30 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile853Ala' Q13563:p.Val846Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain V A Tue Jul 12 10:07:16 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 14:55:26 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val846ala' Tue Jun 30 16:54:21 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val846Ala' binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain PC1 9 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain P98161:p.Gln4225Pro mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain Q P Tue Jul 12 10:07:13 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:48:39 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln4225pro' Tue Jun 30 19:15:15 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln4225Pro' fusion protein fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association f4a homomint mint pkd2-pkd2-1 5 PC2 8 anti tag western anti tag western blot anti tag western predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified Q13563:p.Leu867Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain L A Tue Jul 12 10:07:01 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 20:24:19 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu867ala' Tue Jun 30 19:18:08 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu867Ala' enzyme tag enzyme tag enzyme tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Q13563:p.Ile853Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:06:55 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 15:01:59 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile853ala' Tue Jun 30 19:08:39 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile853Ala' Q13563:p.Val846Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain V A Tue Jul 12 10:06:54 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 15:38:51 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val846ala' Tue Jun 30 17:22:43 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val846Ala' Q13563:p.Ile860Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:06:53 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:11:12 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860ala' Tue Jun 30 17:16:57 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Ala' binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain PC2 8 anti tag western anti tag western blot anti tag western predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain CC2 gst tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined direct interaction direct interaction homomint mint fs1a pkd1-pkd2 5 PC2 8 anti tag western anti tag western blot anti tag western predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified Q13563:p.Ile853Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:53:40 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 15:52:50 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile853ala' Tue Jun 30 20:25:43 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile853Ala' Q13563:p.Ile860Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:14:19 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 18:55:26 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860ala' Tue Jun 30 17:59:16 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Ala' Q13563:p.Val846Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain V A Tue Jul 12 10:14:18 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:59:17 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val846ala' Tue Jun 30 15:43:56 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val846Ala' Q13563:p.Leu867Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain L A Tue Jul 12 10:14:15 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 18:22:35 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu867ala' Tue Jun 30 20:00:44 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu867Ala' enzyme tag enzyme tag enzyme tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain PC1 9 anti tag western anti tag western blot anti tag western predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified mbp tag mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain CT2 direct interaction direct interaction homomint mint fs6a pkd2-1 2 PC2 8 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified Q13563:p.Val846Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain V A Tue Jul 12 10:14:46 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 14:47:52 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val846ala' Tue Jun 30 17:26:59 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val846Ala' Q13563:p.Ile860Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:14:40 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 15:28:01 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860ala' Tue Jun 30 18:47:19 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Ala' his tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Q13563:p.Leu867Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain L A Tue Jul 12 10:15:18 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 14:57:14 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu867ala' Tue Jun 30 17:33:40 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu867Ala' Q13563:p.Ile853Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:15:17 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 15:54:30 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile853ala' Tue Jun 30 18:33:02 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile853Ala' binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain CT2 Stoichiometry: 2.0 direct interaction direct interaction f2b mint pkd2-1 6 PC2 8 weight by staining molecular weight estimation by staining weight by staining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified Q13563:p.Ile860Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:11:20 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 15:23:30 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860ala' Tue Jun 30 17:55:28 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Ala' Q13563:p.Leu867Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain L A Tue Jul 12 10:11:18 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 18:29:04 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu867ala' Tue Jun 30 17:55:41 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu867Ala' Q13563:p.Ile853Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:11:48 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:57:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile853ala' Tue Jun 30 18:29:12 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile853Ala' binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain CT2 Q13563:p.Val846Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain V A Tue Jul 12 10:52:11 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 18:06:10 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val846ala' Tue Jun 30 19:04:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val846Ala' his tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 2.0 direct interaction direct interaction f2c mint pkd2-1 6 PC2 8 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified Q13563:p.Ile853Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:52:08 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:14:53 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile853ala' Tue Jun 30 19:07:41 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile853Ala' binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain CT2 Q13563:p.Ile860Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:52:06 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 19:26:51 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860ala' Tue Jun 30 19:04:50 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Ala' Q13563:p.Val846Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain V A Tue Jul 12 10:52:05 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:10:03 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val846ala' Tue Jun 30 18:21:16 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val846Ala' his tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Q13563:p.Leu867Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain L A Tue Jul 12 10:12:08 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 15:03:34 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu867ala' Tue Jun 30 18:34:33 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu867Ala' Stoichiometry: 4.0 direct interaction direct interaction f2c mint pkd2-1 1 PC2 8 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Q13563:p.Leu867Ala mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing certain certain sequence position certain certain certain sequence position certain L A Tue Jul 12 10:52:16 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 15:16:07 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu867ala' Tue Jun 30 18:58:10 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu867Ala' Q13563:p.Ile860Ala mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:11:53 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:57:41 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860ala' Tue Jun 30 18:07:45 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Ala' Q13563:p.Ile853Ala mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:12:26 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 15:10:38 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile853ala' Tue Jun 30 20:21:01 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile853Ala' Q13563:p.Val846Ala mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing certain certain sequence position certain certain certain sequence position certain V A Tue Jul 12 10:52:34 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 19:43:03 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val846ala' Tue Jun 30 20:07:25 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val846Ala' Stoichiometry: 2.0 direct interaction direct interaction f2d mint pkd2-pkd2-2 3 PC2 8 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined PC2 8 anti tag western anti tag western blot anti tag western predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association f2e homomint mint pkd2-pkd2-3 3 PC2 8 anti tag western anti tag western blot anti tag western predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined PC2 8 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association f2e homomint mint pkd2-pkd1-1 3 PC2 8 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined PC1 9 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell flag tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P98161:p.Gln4225Pro mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain Q P Tue Jul 12 10:54:45 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 19:34:37 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln4225pro' Tue Jun 30 18:58:00 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln4225Pro' physical association physical association f4b homomint mint pkd1-pkd2-1 3 PC2 8 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined PC1 9 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell flag tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P98161:p.Gln4225Pro mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain Q P Tue Jul 12 10:16:30 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 17:53:15 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln4225pro' Tue Jun 30 16:32:48 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln4225Pro' physical association physical association f4b homomint mint pkd2-pkd1-2 3 PC2 8 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell Q13563:p.Ile853Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:54:54 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 19:35:15 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile853ala' Tue Jun 30 20:25:51 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile853Ala' Q13563:p.Ile860Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:16:46 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 17:27:21 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860ala' Tue Jun 30 19:21:59 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Ala' tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Q13563:p.Val846Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain V A Tue Jul 12 10:54:52 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 19:22:03 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val846ala' Tue Jun 30 18:36:58 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val846Ala' Q13563:p.Leu867Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain L A Tue Jul 12 10:54:50 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:26:06 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu867ala' Tue Jun 30 18:36:35 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu867Ala' PC1 9 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell myc tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association f4c homomint mint pkd1-pkd2-2 3 PC2 8 anti tag western anti tag western blot anti tag western predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell tag tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Q13563:p.Ile860Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:54:34 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 20:24:21 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860ala' Tue Jun 30 15:52:20 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Ala' Q13563:p.Ile853Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:16:15 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:49:34 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile853ala' Tue Jun 30 20:14:24 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile853Ala' Q13563:p.Val846Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain V A Tue Jul 12 10:16:15 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:06:10 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val846ala' Tue Jun 30 19:20:53 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val846Ala' Q13563:p.Leu867Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain L A Tue Jul 12 10:16:12 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 15:09:58 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu867ala' Tue Jun 30 19:19:01 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu867Ala' PC1 9 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell myc tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association f4c homomint mint pkd1-pkd2-3 4 PC2 8 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified Q13563:p.Leu867Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain L A Tue Jul 12 10:23:40 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 14:55:39 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu867ala' Tue Jun 30 18:31:13 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu867Ala' binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain CT2 Q13563:p.Ile860Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:58:42 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 17:18:39 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile860ala' Tue Jun 30 17:53:38 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile860Ala' Q13563:p.Ile853Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain I A Tue Jul 12 10:23:30 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 20:30:44 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile853ala' Tue Jun 30 19:33:58 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile853Ala' Q13563:p.Val846Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain V A Tue Jul 12 10:58:40 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 17:06:54 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val846ala' Tue Jun 30 19:29:11 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val846Ala' PC1 9 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain CT1 direct interaction direct interaction homomint mint fs6b