IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. Dev. Biol. (0012-1606) 2010 imex curation Fridolfsson HN., Ly N., Meyerzon M., Starr DA. dastarr@ucdavis.edu 13-Sept-2010: Contacted by JYOTI. orchard Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Fridolfsson HN., Ly N., Meyerzon M., Starr DA. dastarr@ucdavis.edu [Daniel A. Starr] dastarr@ucdavis.edu Accepted 2010-SEP-31 by ORCHARD. 13-Sept-2010: Contacted by JYOTI. Dev. Biol. (0012-1606) 2010 orchard Only protein-protein interactions imex curation UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. Dev. Biol. (0012-1606) 2010 imex curation Fridolfsson HN., Ly N., Meyerzon M., Starr DA. dastarr@ucdavis.edu 13-Sept-2010: Contacted by JYOTI. orchard Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Fridolfsson HN., Ly N., Meyerzon M., Starr DA. dastarr@ucdavis.edu [Daniel A. Starr] dastarr@ucdavis.edu Accepted 2010-SEP-31 by ORCHARD. 13-Sept-2010: Contacted by JYOTI. Dev. Biol. (0012-1606) 2010 orchard Only protein-protein interactions imex curation UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. Dev. Biol. (0012-1606) 2010 imex curation Fridolfsson HN., Ly N., Meyerzon M., Starr DA. dastarr@ucdavis.edu 13-Sept-2010: Contacted by JYOTI. orchard Only protein-protein interactions human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Fridolfsson HN., Ly N., Meyerzon M., Starr DA. dastarr@ucdavis.edu [Daniel A. Starr] dastarr@ucdavis.edu Accepted 2010-SEP-31 by ORCHARD. 13-Sept-2010: Contacted by JYOTI. Dev. Biol. (0012-1606) 2010 orchard Only protein-protein interactions imex curation UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. Dev. Biol. (0012-1606) 2010 imex curation Fridolfsson HN., Ly N., Meyerzon M., Starr DA. dastarr@ucdavis.edu 13-Sept-2010: Contacted by JYOTI. orchard Only protein-protein interactions human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 fluorescence imaging fluorescence microscopy fluorescence imaging tag fluorescence tag visualisation by fluorescence tag fluorescence Fridolfsson HN., Ly N., Meyerzon M., Starr DA. dastarr@ucdavis.edu [Daniel A. Starr] dastarr@ucdavis.edu Accepted 2010-SEP-31 by ORCHARD. 13-Sept-2010: Contacted by JYOTI. Dev. Biol. (0012-1606) 2010 orchard Only protein-protein interactions imex curation UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. Dev. Biol. (0012-1606) 2010 imex curation Fridolfsson HN., Ly N., Meyerzon M., Starr DA. dastarr@ucdavis.edu 13-Sept-2010: Contacted by JYOTI. orchard Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Fridolfsson HN., Ly N., Meyerzon M., Starr DA. Only interactions observed in at least 3 independent experiments were taken as positive. dastarr@ucdavis.edu [Daniel A. Starr] dastarr@ucdavis.edu Accepted 2010-SEP-31 by ORCHARD. Dev. Biol. (0012-1606) 2010 orchard Only protein-protein interactions imex curation egal1_caeel Egalitarian protein homolog egal-1 C10G6.1 protein protein caeel Caenorhabditis elegans MEEAKNMALLFFMDHLMQKNGRRTIHDLSCQFGARGFSEEMRNAVGTTQEGLTEFLQGHPSLFTVEGDQVILNGHNDLNAKNNPLLQSGIRSRNYEKEAVDFFVTKLTKFGPELQIKSLLGHRSQAAPEVRLVSGRHLKEFCEFLQSQVDYFVVEGDRVRLKNMPEPDENAIEMDDEGRPLAGVKAKQAAVEYLKSVLEQNEDQPIPLDQFYQNFCQRFSHTIRQDVATNPKELLQFLKLNRGLFFIRSNKVSLVKNRLNEDGSENGSDEGEETNNNGMFPLDQSALTRIHFVKALKPAQDLISRLWQDINNMEKKVVGLDLKTVTVGVDGEIFLSLGVIATTSQIGIFDLASSDVIILESGFKGILESEKVVKVIHDARRVASLLAHKYAVHMRNVFDTQVAHSLLQHEKFNKSLNEMRPISFINLQRVYYPQSIMLSDVTPRKMSMCPNWGVRPITEEFQLTIVEEAHCLLSALYQSLSNLIPVHLRGVFEDKCIEVNHPEVLLASPNRPPPQPFISSPYRASTRRDVRNGGSIMQSFSPAPYAAAPRPQMSDACTQTFSTGDIEVLNVFYE F9EB08582F3FA5FF nud2_caeel Protein nud-2 nud-2 R11A5.2 protein protein caeel Caenorhabditis elegans MDLSEDQIRGLPHHELLGHFLQMREEFNEFQTSSAEIEKMMDSELDDLKTQLKKAETRVQQMTTEQIRNKDRQDDSRVQFAQVEEQLRRENSHLHEQCESQRERIRKLEQRNDVLETSERNKEYLASDLGSKLDHAIEKIAMLESELYERQVAAEEMHRLREEQLRTTERPRLIVEPLRNDPEILPDEPSPGPSKEEFKMSSEDVFMEDVQHHEDVRMEETIAKIDEVRIDDNKNIQEKSQRVSTGTGAGACINRIVKDLMTKVERLDSILSTIRVSNNSSNNNSSHLTTTRA 84E075C3DC96C3D9 pat12_caeel Protein pat-12 pat-12 Paralyzed arrest at two-fold 12 protein T17H7.4 protein protein caeel Caenorhabditis elegans MTSHIATETSVNRWSTEPVVREEGRPPGPEDFPSTKQGREQDGNVIGITPNYKIGEQKPNSELNLGKTGSLPRGSGDYKMTYRQEDYKQTIIDPKVITNANMPYISTRIPDPRRNLAGDFPSEHSKSKIKLDPLEQRRFRSSESRPITTSNYLAESVDRHREMEASRLREYLKAKENEANQPWNKPGWPGPKKNDESLRELETMKQRIETLKRDANKGPVNAELDELSKRAEELRKRDGWSKYKLVESDIYKTDPDPMPANIKDQVRDLLESRNSVETTTTQRDHDKSGYVTDVSTATWNFSTVDYSPRSVVSMNGASHDILKDDKPRSIMKRNDLVRREQMLYPTVDTQVVKSVVKKPTVTETVQRFEETRRTEEVERRVQRREKKERRSRHHSSSRHHSGWEGHTGGYQGHRSSSLSRGGHGGGGQETYYRQETTRRQQHNNYDDNFNRGIAHARYGSLSDSLRRGELQYVPNGEVRQSFYRDGSNGGQRMHKSYSTRDVFTGDGYDDRRSVSSFRRGSQQQVSPFVEFPPTLPRRGGGGDYRREEDAYFRPVSKSRSYADWDDAGRAGMGREVRRYDDDMSRLEAEFRDSLLMPMPAGNMNERDHRTEQLPGGYETFNKERHANSGRRSGRDGKPVDFNEATQEYNYKREQTLNDDRRRR 416F3943DB9A7ACA mel26_caeel Protein maternal effect lethal 26 ZK858.4 mel-26 protein protein caeel Caenorhabditis elegans MEPRIDGGVFIGGIGNSGNEMCSNGVPALGVSSQTEIKVEKVQHTWTVKNFSHCYQEYLENFVYLQRGDEQLTWSIKIYPKGNGENNKDFVFLCLNRVINNNVKAGKIGFKSQFKLRTAENKDIEMRIHPNPSHSDYVSYIKRDVLFPQIMPRDMIIVNVEIDVAVETITTTNEPIQFEPTNSEQQLIEDYQRLFSQELLCDFAINVNGKIIRAHKAVLAARSPVFNAMLTHQDTDEAKSSMMYINDMDYDVIYEMVYYIYCGRCNKDITDMATALLIAADKYRLEELKSHCEKYLVENINIENACSLLIIGDLYSAPKLRKRAVTYILARPKNVTGTPGWEDILKGHPNLITDIFSQIDRQSSTGATSSVSNLPGVPMDIPGITGNIVPPPSGL 3AED944583A155AC unc83_caeel Nuclear migration protein unc-83 unc-83 Uncoordinated protein 83 W01A11.3 protein protein caeel Caenorhabditis elegans MDVMDSFSEVEMPNDISSEDHLLKVIESSAEEVDIFLENCSSLYNLILDSLHNLTSKTISCECLDEMTSTLEKSAKKILAERPEAENSVLLRLNTICCAMDQLRVQHNSRMMSGADSDTASSARSSTSSSTGEMRLWLHEVERRLEINEKRIRVEPNLQLLLSDQQALQLEIQHEGQLLVNRLNKQIKDDHDSDSSEEEKRKTCVDAIRKRWHTIYLNSLSLVCRIEELINHQQASEDSESDPDLVGPPIKRARIRTVGHLTASDTEESEADEEDRHSQTETVVTEDDNVLPFAENEYESIMDGRVTVDSCTSSSEDQMVEQSTNKKWESVLQDVGYSSGENSIHEALNTCADHLVPETSDMRRKRIECSPVKAFYRTVQLEDMSDLEVTKAINHDVEEEPNLSDSMYVNHDSTFLATQNLPEYDEVMALMDDDDLPMDMSMTESFNTKWREIHGQKKPLRRASRPSREQMNLIAKSSCDASSEDSSEGENQTNLEDDPEMMSVSFNSAQFDTSSPLKRQRSARGLKNASFLYDSLEMDGSFCSTRSEMLPPCKTRSLARRKLRVRRMPRSMSDGEQLGVVSSKPEGMMTPMIRVSPPSTPVRRLLRKLDEQIRNRDSDTAPEHSDAAQAYEWDEYNPPQKDDSISDRHIQTMTDISDQLMNIDDDFAEHFGTSSAIRLIEESKSHLRVVLKALEESDSNIPQLSNFELIARSNLRQVDEALKIQSGNQPSFLETSTLQDLRSEWANLYESIRSPFARIMHQVKKFAATLQEVSSMASLGDVDIRSKEDVAKTLDAVTAIERRLSSERQELRDLLASSSFRDVAKDLSCEFESVSEGYDDAVDKIGKMAHSLSQVKGEWDAWNSRQNDIRNAMVRIESHLKEGQMDNKMIADEMELCQERMNSLETMCNYLTASLGSIQNESNSKNLPDFKAELSIYSNALARLKDRFNDMIRVPTPPTVQFHPPEPLPSLARSMTTQTAEMESETENEPLTIAEAISSSRLIKFTFALSLLAALAAIFYYHVFGKPFGPHVTYVNGPPPV BB403A9A7C41A01F dyl1_caeel Dynein light chain 1, cytoplasmic dlc-1 T26A5.9 protein protein caeel Caenorhabditis elegans MVDRKAVIKNADMSDDMQQDAIDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 72831C3103C2294E h2kz24_caeel C27H5.2 CELE_C27H5.2 protein protein caeel Caenorhabditis elegans MSSITGLQVKSLRIGVEPVEVELDEDAGILWTSLQTAFPGCSGMYYREIGDSCKKSVKFDGKKFMAPGGAWNDREYFVTLSQRCHTAAGNSGHTASYSDATKQFEKSVQAVQKMMLASGMKIDMSHLTKKRQHTSSRETASSTSSSTVTPDPIQAIEERSQMLKTAGRELSPLEQQFLDLCRISTAKDQIIDANRQEITKMNETLRILEKNLKETETNLSEANAMVDCKQQELEMVSEALKRLEESRHTISELNRKSGNLEENVTELQMKLMNVEEENHGLKAQLETSHNRIKEMSDTISMLTSSKDILSKELDQLRPFADAAGIEDYENIPTFIHAIQENKELRKTNENMKLQSEETKDNHKQMQSIHTEVFEENAKLRNRNEDLERRFAHVDDELACVNENWAKELKEKQQDWDKVKYAAESEVLSLREQLVHLQSILESATREAAENARRVSELEHERHEVRRLSDAMHIKAQEDLARQVRVLKERLAESDSQVAELNVLVSSLAADATASRREISDLL 8F1875875E0678DF g5ecd7_caeel mel-11 C06C3.1 CELE_C06C3.1 protein protein caeel Caenorhabditis elegans MGQDDEDDAHMLQAKQQITFNVVNKRKDQLRRWQSSEMNAEAARRTKRPKVQFQDSDIFLSACMSGDEEEVEELLNKGANINTCTVDGLTALHQSVIDSKPEMVRFLCEKGADVNAQDNEGWTPLHAAACCGNVAIVRYLCQHGADLSIVNSDKELALDLAVDEQCRDYLDDDYKRQMIDLDACRDQELQTMLKDVNMWMSQGEYRDIPHHRTGGTAMHVAAGRGYTQLLELLIKAGGNVRAQDVEGWTPLHAAAHWAERDACKILLENGAELSDLTFTGADVLGVADKECIDYLVELADTVKVQNKRKSPGSGSQPPTSILQEKNHRMPSHEEHVLTSERKRDLQHKDQHSENEFLHSHPSTASVGSTTSSNTNTTTTTIVIGENDISAAQKDSRESSKESAVDDEEYVAEDEMEEAEEDEEEEDVEEEEEEKSEAELKNGKEISPLRSETTSSRSISITRSLDGYTDRSSSGRETSAEMSEAASSASTGTTSSSSRFTSSTPSSQRSAAGSVHTETPRSSMENSSSVGSGDQNVSATIPIVPLSAPPKAVHQSPSSWINRGVPLSSRSSTSSVTRSSSTPVSEIISPPSSIHSQLSFPSVSNTTTTTATVAPTSSTVPSTPVSNVMAATISSTAKNTPSPAGSVTTINATFSKPSSRHPSEEVYRSPSQPTNVPWASLWHNVNNASTGQIRSHIEQLRNASFSSLSSYPRVSAFRSPIKTTASSTSVNSASSPLLLQPHPHPPVIAEYPRGFVPQQINPNKMSRWQSKTVTESEAERRNNSRMQRQHRRSTQGVTKEQLEEASKFATDEVARRNSQVLSTYPNSLHARLASEEKDLSSTSDDLKDGDVSTTATVSLINSPNSNSANVRRKSQGLSISRSNRRATGPVNPEDLAPAMSLRLATAQPYSPASVRSNAGTLPTMTSRFSEKAQSLPPASNGMSSTQPLSTRSAIVAGLSSAPSMRTTAPLSSTATSSRFMPSSSLSSNGSSANQQPSSIYGLQSRPTETNLNYKALFEKERSECERLRREMEEMRRSQTADSYRGASTQLAWRARNASPSAQPHNLSVAKSTSLASFDENERRSMERKISDLELQLKTATNLRMENQRLKEENGALVRVISKMTI 2E8FC5358AC56169 o76640_caeel math-41 T08E11.4 CELE_T08E11.4 protein protein caeel Caenorhabditis elegans MANQDQNYLGPRTHPPNLQKSTSFSGAKLHYQYQYTGKEQKTSSSKDESRVHHSESRSPRLSKHLAEDDGSGSTLDQRLSRQLTVDYGGGSTVDQRSQLGTSGTKYLTTVQSSNLDSAASPLSFSGHTAPSKIAVVRETLPVSSQASIFPTSYRSSQYPFLNPSTKVTTTPPIQQSHLGTSRLTTVQSSNLDRSPSPSRSRYMNSRDRRKTTTIIPSSIPQSSEYKSAFQREAPAVYFNQHTESQSTYKPLPMSSQTQNRNLTIGYTPNQFQEIERAQREFKNQKKQEEEIRAKLDRRRIEESQRLEAERFALEATMVDEDEDVAKFIRNPEERFKDSRDSKKLEWRSRRAPNQPEQVCGESCENAKLGKFGKFAKLSKYGKFARLGKFGKFATLGKFSKYYIRTMPNSCKEFSISENVKNISRFVDGERYHTNLEDRFNIPWRIRIEKTNDNFQLYLRCEKEECENRKWSIETEITLKLVSHNGKSLMKNWKYTFAKPTGRGFEFISWKELESDYVVDDSIVVEAHVKILNILDSPCTETMNQKTFMLNHTVQNVSNIKERGIYTTNVETHYNIPWRIEIQRREGFFGMYLQCEKKHFDSKDWSIEVELVLTLKSSNGQRLSFTASSTLNEPASYGYDKLIRWDDMERKYAVNDSIIIEARVKIIKMTGFEERPPVGRLSGIVIPVGDREYSMEEWMEMAFGC 0896CA23591F8711 q5fc73_caeel F54D5.5 CELE_F54D5.5 protein protein caeel Caenorhabditis elegans MHYLVFFDLLFKPPITLSPIDLPTFPVHISLSVKVSATHSIGPHVLPIDHPVRLALISHSADTTKMAAIIRTLFKSKKSKKGDEENNEDLAREVSNRRSFRAPSTSSSKSQRRAVARFADDGALPATAAYHTTSAPKLRKGPQSCPGGYRDESDVSYESDKYSQKSNSHRRRDVLHQSMRQNYTIDEGRKPSSRRHHSSKSDFRRRGESSEYGSGDPSPVGQYSSRHSHYEDRIEESENDDFSEKAQFAVIERAQQHYMQKYKESEQKRREEKRKLKDMEKECNDAKNAMFHYMNQLDKVKKERDCYRKELSRCKKQLEAFQNSGYDAFHHLRQPQISNPQQYPPPLSMGSYPYMSQSMNASHHMSSNFMNSAPPSSNTPMTMTSGAGESLINPSDVSFLQNSFLQPTSQGLTGMTPPPGGFKVPTNYGDDDRDEVKDYRSELLIETSRSTKEVDSISPSSSADSQVTLLDHSTIDKENRKPPSRPFSMMSI 6030017856717C2E mysp_caeel Paramyosin unc-15 F07A5.7 Uncoordinated protein 15 protein protein caeel Caenorhabditis elegans MSLYRSPSAALLKSPSQAAFGAPFGSMSVADLGSLTRLEDKIRLLQEDLESERELRNRVERERADLSVQVIALTDRLEDAEGTTDSQIESNRKREGELSKLRKLLEESQLESEDAMNVLRKKHQDSCLDYQDQIEQLQKKNAKIDRERQRVQHEVIELTATIDQLQKDKHTAEKAAERFEAQANELANKVEDLNKHVNDLAQQRQRLQAENNDLLKEVHDQKVQLDNLQHVKYTLAQQLEEARRRLEDAERERSQLQSQLHQVQLELDSVRTALDEESIARSDAEHKLNLANTEITQWKSKFDAEVALHHEEVEDLRKKMLQKQAEYEEQIEIMLQKISQLEKAKSRLQSEVEVLIVDLEKAQNTIALLERAREQLERQVGELKVRIDEITVELEAAQRELRAVNAELQKMKHLYEKAVEQKEALARENKKLHDELHEAKEALADANRKLHELDLENARLAGEIRELQTALKEADAQRRDAENRAQRALAELQALRIEMERRLQEKEEEMEALRKNLQFEIDRLIAALADAEARMKSEISRLKKKYQAEIAELEMTVDNLNRANIEAQKTIKKQSEQLKILQASLEDTQRQLQQVLDQYALAQRKVAALSAELEECKTALDNAIRARKQAEVDLEEANGRISDLISINNNLTSIKNKLETELSTAQADLDEVTKELHAADERANRALADAARAVEQLHEEQEHSMKIDALRKSLEEQVKQLQVQIQEAEAAALLGGKRVIAKLETRIRDLETALDEETRRHKETQNALRKKDRRIKEVQQLVDEEHKNFVMAQDTADRLTEKLNIQKRQLAESESVTMQNLQRVRRYQHELEDAEGRADQAESSLHLIRAKHRSSVVTGKSSSKIFVTEDDY D3146CC6547EBD75 klc_caeel Kinesin light chain klc-2 C18C4.10 protein protein caeel Caenorhabditis elegans MSNMSQDDVTTGLRTVQQGLEALREEHSTISNTLETSVKGVKEDEAPLPKQKLSQINDNLDKLVCGVDETSLMLMVFQLTQGMDAQHQKYQAQRRRLCQENAWLRDELSSTQIKLQQSEQMVAQLEEENKHLKYMASIKQFDDGTQSDTKTSVDVGPQPVTNETLQELGFGPEDEEDMNASQFNQPTPANQMAASANVGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAANLLNEALSIREKCLGESHPAVAATLNNLAVLFGKRGKFKDAEPLCKRALEIREKVLGDDHPDVAKQLNNLALLCQNQGKYEEVEKYYKRALEIYESKLGPDDPNVAKTKNNLSSAYLKQGKYKEAEELYKQILTRAHEREFGQISGENKPIWQIAEEREENKHKGEGATANEQAGWAKAAKVDSPTVTTTLKNLGALYRRQGKYEAAETLEDVALRAKKQHEPLRSGAMGGIDEMSQSMMASTIGGSRNSMTTSTSQTGLKNKLMNALGFNS BDA3B2CD06D38D06 h2kyj3_caeel bath-44 CELE_C07D10.2 C07D10.2 protein protein caeel Caenorhabditis elegans MDNSLMQMRHAADSWSTSEVRSLVHKHMWTIRGFSQLECRYLETSAKIKDITKDESGLQVPLTHQPSSSGGLPELPDITFRIRLHPQGNKESNKDFTFFQCFTNQATTTTTPTFRAKFKFTVFNQRTEETPTTVYSGTQQLHGYFEYIRREVLVGHVQPADDLILCLTITITFDTVTKAAQNTRSVPPELPMPSDVTKDLENLYRSGKHADFTLVVEERELKAHKAILAARSPVFAAMMEPHTAEAQNSRAILRDIDYEVVQAILYYIYTGTCTNMGGNALDILAAAERFALPGLKNIAEVAMRNGLATETVCKNLAFAEMYGLVDFKKEAIKYICMNANAVINSEGFLRLSRQNPDLIVDIMTVLVNERHNSPSCFSLDGTLEPASKRARMTETNL C2E720ABA7B07E12 ess2_caeel Splicing factor ESS-2 ess-2 ES2 similar protein 2 F42H10.7 protein protein caeel Caenorhabditis elegans MSSFDKNDERAQLMVPKSINEGKVVKLSQKTLVTKKIERQVVPEEKYIAGLDKIIEKDYFPHLKKMQAQKEYLEAVANKDINKIKELQMKFCSTGSVRTDRSFRTPITTRSTTEAPDVSSFDADTPGPSSASTSSAHDWMQSPMPFANEEGDNEALNRKRKKKKEETLTSYLNKYTSEDNASFEELAKVMREREDARRPWVYKAEEEHNKNLVTRQAIAAEADVQLALKHAVDADDNRPLNVDNWAYKAWNTVLFNPDGAALTPAEIADAARKQQTEINKRGTRFPDSGKLKPSDEAMTRAAVSHALANAGKVDFLGNEVTPANSFKLLETPNPNPDDMDSPLMTWGEIDGTPFRLDAPDVTEHSLPGAAPVFKIPEVPYREKIAQSMNDSIAAKYRDKRKVAMRAAEGAHFSRTPGFGSKRVSDKLAQLSPAAQKLATKKLGLKMLPAHKSPFASPKIMSNWSRPSSSKRSTTPGSAWSRGSTTPGSSWSQGAQTPGTPGIESMIRRKGDNVGPSTSAGAADRANAGDFF 809E5BA29DC4173D bicd_caeel Protein bicaudal D homolog bicd-1 C43G2.2 protein protein caeel Caenorhabditis elegans MAESELEKLRQDIAILTEKYEQAKEDIHKAANAGLELLRQKEDLEKRLAEMQAELDLARTEIDKTNQTLAEYRSQHQRSTRSELENEESLLEESSAKEEEYLQRIAKLEADLKKKEQELAEKKEELESIEKKHSKEIDSGAALEDERRKLRAELKETKEREQRLISEYSELEEENIGLQKTVANLRGSQVEYESLRIDNNRLEETIEIMKMAAEEDEILRVIADKQLEEALLTAQQERDQRLAMKRELEQTRNAEHISSLNDMLFGLERLGEDGELPPPQPGASDLFSELQGSSDVKVRELEAAKEGLQEELKSREKIFIEFVTGLADTLNIHRPTNELDYMHARQQKDVVLEKIQNIARDTDRHDKEGEEKRSGILKADLRTLVLVAGEKSAQLAAAQDAMIQVSDQLYQFYHQMTQNQGVQTEKSVQEIVKKLRLLARANAEDVPRVSLADEGVESGTETDVNASRSIPLNSDRLVIAPSFAKEIEKKLASVKIGDVLSETDLRQRILTEGNAISETTESLKKMIQVVKRTSEQAFNQAVMASGAENEIEMQNMKLRSLLSTKRDQISTLRTVLKSNKLTAESALTSMREKYESEKKMMMEINDKMRRELKQLKEDAATFASHRAMFTARGEELKSKVEELSNELRANEEEKKTLNQLLRLAIQQKLTLTQRLEEVEVDRDRQVFKRSSTRAPTRETYQPPRAVRYPGSTTTAQQPAPSSSGGSRGGPRRGDNQQ A0A4803FAE0F6473 q23064-3 Nuclear migration protein unc-83 unc-83 Uncoordinated protein 83 W01A11.3 protein protein caeel Caenorhabditis elegans MDGRVTVDSCTSSSEDQMVEQSTNKKWESVLQDVGYSSGENSIHEALNTCADHLVPETSDMRRKRIECSPVKAFYRTVQLEDMSDLEVTKAINHDVEEEPNLSDSMYVNHDSTFLATQNLPEYDEVMALMDDDDLPMDMSMTESFNTKWREIHGQKKPLRRASRPSREQMNLIAKSSCDASSEDSSEGENQTNLEDDPEMMSVSFNSAQFDTSSPLKRQRSARGLKNASFLYDSLEMDGSFCSTRSEMLPPCKTRSLARRKLRVRRMPRSMSDGEQLGVVSSKPEGMMTPMIRVSPPSTPVRRLLRKLDEQIRNRDSDTAPEHSDAAQAYEWDEYNPPQKDDSISDRHIQTMTDISDQLMNIDDDFAEHFGTSSAIRLIEESKSHLRVVLKALEESDSNIPQLSNFELIARSNLRQVDEALKIQSGNQPSFLETSTLQDLRSEWANLYESIRSPFARIMHQVKKFAATLQEVSSMASLGDVDIRSKEDVAKTLDAVTAIERRLSSERQELRDLLASSSFRDVAKDLSCEFESVSEGYDDAVDKIGKMAHSLSQVKGEWDAWNSRQNDIRNAMVRIESHLKEGQMDNKMIADEMELCQERMNSLETMCNYLTASLGSIQNESNSKNLPDFKAELSIYSNALARLKDRFNDMIRVPTPPTVQFHPPEPLPSLARSMTTQTAEMESETENEPLTIAEAISSSRLIKFTFALSLLAALAAIFYYHVFGKPFGPHVTYVNGPPPV 1B1C06D66C9E2F88 ylu3_caeel Uncharacterized protein F10E9.3 F10E9.3 protein protein caeel Caenorhabditis elegans MASKTRRGSSLAKKEKEIKKEIEEDKEVAPIQEEDDDGPPPILEREASCGENDDTDGDGKEEDAQKEDDIDGSKTKNESILEALSQFFTADDATVKNRRNSPPSESSSTRNTLGLNRGGAIPKALLLNKNLRPVPSKTPPIATTRFASLRHLSSAPGTSASTSGSPSVGIRKYGVPPPMPRSLRNIAGSINVVGSNSSLGPARLLESRKRHFDKDKDGKNPKRSSLVAYNGGRAGENFRKVPPSAVSPAPGSGSSASSGTSTSSSNGIIDVQSMLRDQSPVRMQVMVGGDHETNGDSIQEAMELANAQKESIGNIARASSHHNMLLGSMIINGLNTLQSRDKDEYTNFSSDLFSLITRYNIN 61CA7300CA94CDA5 dlc1-egal1-2 1 6 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey dlc1_1-89 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Fig. 5. dlc1-unc83-2 1 10 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 11 unspecified role unspecified role prey prey physical association physical association Fig. 5. bicd1-unc83-2 1 20 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Fig. 5. bicd1-egal1-2 1 20 unspecified role unspecified role prey prey bicd1_253-737 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 6 unspecified role unspecified role bait bait physical association physical association Fig. 5. unc83c-klc2-1 5 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 17 unspecified role unspecified role prey prey physical association physical association author score author-based confidence author score 20 Table 1 unc83c-dlc1-1 5 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 11 unspecified role unspecified role prey prey physical association physical association author score author-based confidence author score 4 Table 1 unc83c-nud2-1 5 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 7 unspecified role unspecified role prey prey physical association physical association author score author-based confidence author score 4 Table 1 unc83c-bicd1-1 5 20 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association author score author-based confidence author score 3 Table 1 unc83c-gei16-1 5 8 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association author score author-based confidence author score 12 There are 12 isoforms for gei-16 (Q95QA6) in UniProtKB/TrEMBL. It is unclear which isoform is identified in the screen so I have used isoform d as this is the longest isform and will be the master entry when the entries are merged. Table 1 unc83c-unc15-1 5 16 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association author score author-based confidence author score 5 Table 1 unc83c-mel26-1 5 9 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association author score author-based confidence author score 6 Table 1 unc83c-mel11-1 5 13 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association author score author-based confidence author score 5 There are 4 isoforms for mel-11 (Q8I0N9) in UniProtKB/TrEMBL. It is unclear which isoform is identified in the screen so I have used isoform c as this is the longest isform and will be the master entry when the entries are merged. Table 1 unc83c-c227h5_5-1 5 12 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association author score author-based confidence author score 10 There are 4 isoforms for C27H5.2 (Q18266) in UniProtKB/TrEMBL. It is unclear which isoform is identified in the screen so I have used the longest isoform as this will be the master entry when the entries are merged. Table 1 unc83c-f10e9_3-1 5 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 22 unspecified role unspecified role prey prey physical association physical association author score author-based confidence author score 5 Table 1 unc83c-math41-1 5 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 14 unspecified role unspecified role prey prey physical association physical association author score author-based confidence author score 3 Table 1 unc83c-bath44-1 5 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 18 unspecified role unspecified role prey prey physical association physical association author score author-based confidence author score 3 There are 2 isoforms for bath-44 (Q95QX2) in UniProtKB/TrEMBL. It is unclear which isoform is identified in the screen so I have used the longest isoform as this will be the master entry when the entries are merged. Table 1 unc83c-ess2-1 5 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 19 unspecified role unspecified role prey prey physical association physical association author score author-based confidence author score 3 There are 2 isoforms for ess-2 (P34420) in UniProtKB/Swiss-Prot. It is unclear which isoform is identified in the screen so I have used isoform b as this is the longest isform and the master entry. Table 1 unc83c-f54d5_5-1 5 21 unspecified role unspecified role bait bait unc83c_137-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 15 unspecified role unspecified role prey prey physical association physical association author score author-based confidence author score 3 There are 2 isoforms for F54D5.5 (Q5FC73) in UniProtKB/TrEMBL. It is unclear which isoform is identified in the screen so I have used the longest isoform as this will be the master entry when the entries are merged. Table 1 unc83c-bicd1-3 2 20 unspecified role unspecified role bait bait gst-bicd1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) 21 unspecified role unspecified role prey prey mbp-unc83c mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) 98 101 physical association physical association egal1-bicd1-3 2 6 unspecified role unspecified role prey prey mbp-egal1 mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) 20 unspecified role unspecified role bait bait gst-bicd1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined bicd-1_227-737 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) physical association physical association Fig. 5D unc83c-dlc1-3 2 11 unspecified role unspecified role bait bait gst-dlc1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) 21 unspecified role unspecified role prey prey mbp-unc83c mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) direct interaction direct interaction Fig. 5B egal1-dlc1-3 2 11 unspecified role unspecified role bait bait gst-dlc1 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) 6 unspecified role unspecified role prey prey mbp-egal1 mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) physical association physical association Fig. 5B unc83c-nud2-2 1 7 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 21 unspecified role unspecified role bait bait unc-83c_362-692 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 121 123 physical association physical association Fig. 6A unc83c-nud2-3 2 7 unspecified role unspecified role bait bait gst-nud2 gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined nud2_239-293 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) 21 unspecified role unspecified role prey prey region mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) 130 127 physical association physical association Fig. 6B unc83c-nud2-4 3 21 unspecified role unspecified role prey prey myc-unc-83c myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined unc-83c_1-698 unc-83-KASH sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 7 unspecified role unspecified role bait bait gfp-nud2 gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Fig. 7A unc83c-nud2-5 4 7 unspecified role unspecified role neutral component neutral component gfp-nud2 gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role neutral component neutral component myc-unc-83c myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain colocalization colocalization Fig. 7B