MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it The tyrosine kinase Csk dimerizes through Its SH3 domain. The tyrosine kinase Csk dimerizes through Its SH3 domain. PLoS ONE 2009 mimix curation Levinson NM., Visperas PR., Kuriyan J. SH3 mimix curation in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column weight identificat confirmation by molecular weight weight identificat Levinson NM., Visperas PR., Kuriyan J. SH3 PLoS ONE 2009 mimix curation mimix curation csk_human Tyrosine-protein kinase CSK CSK C-Src kinase Protein-tyrosine kinase CYL protein protein human Homo sapiens Human MSAIQAAWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTHELHL 431023A88C54E00C csk-1 1 csk 2 weight identificat confirmation by molecular weight weight identificat predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Stoichiometry: 2.0 direct interaction direct interaction mint f1 f2b csk-1 1 csk 2 weight identificat confirmation by molecular weight weight identificat predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified P41240:p.Tyr18Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain Y A Tue Jul 12 10:59:00 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 17:56:12 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr18ala' Tue Jun 30 15:47:05 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr18Ala' Stoichiometry: 2.0 direct interaction direct interaction f2b mint csk-1 1 csk 2 weight identificat confirmation by molecular weight weight identificat predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified P41240:p.Phe20Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain F A Tue Jul 12 10:23:47 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:20:52 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe20ala' Tue Jun 30 19:54:37 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe20Ala' Stoichiometry: 2.0 direct interaction direct interaction f2b mint csk-1 1 csk 2 weight identificat confirmation by molecular weight weight identificat predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified P41240:p.His21Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain H A Tue Jul 12 10:06:45 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 19:22:54 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'his21ala' Tue Jun 30 18:13:19 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.His21Ala' Stoichiometry: 2.0 direct interaction direct interaction f2b mint csk-1 1 csk 2 weight identificat confirmation by molecular weight weight identificat predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified P41240:p.Thr23Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain T A Tue Jul 12 10:06:43 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 14:28:05 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr23ala' Tue Jun 30 16:53:17 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Thr23Ala' Stoichiometry: 2.0 direct interaction direct interaction f2b mint csk-1 1 csk 2 weight identificat confirmation by molecular weight weight identificat predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified undefined mutation mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain Wed Jul 06 17:03:20 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'mutation disrupting' Asn47Ala Stoichiometry: 2.0 direct interaction direct interaction f2b mint csk-1 1 csk 2 weight identificat confirmation by molecular weight weight identificat predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified P41240:p.Tyr64Ala mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain Y A Tue Jul 12 10:06:32 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 20:17:57 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr64ala' Tue Jun 30 18:45:41 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr64Ala' Stoichiometry: 2.0 direct interaction direct interaction f2b mint