MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Capns1, a new binding partner of RasGAP-SH3 domain in K-Ras(V12) oncogenic cells: modulation of cell survival and migration. Capns1, a new binding partner of RasGAP-SH3 domain in K-Ras(V12) oncogenic cells: modulation of cell survival and migration. Cell. Signal. (0898-6568) 2008 mimix curation Pamonsinlapatham P., Gril B., Dufour S., Hadj-Slimane R., Gigoux V., Pethe S., L'hoste S., Camonis J., Garbay C., Raynaud F., Vidal M. only a selection of interactions described in this publication have been curated SH3 suggested by mcarducci partial coverage mimix curation in vitro In vitro competition binding competition binding western blot western blot Immuno blot Immuno blot Pamonsinlapatham P., Gril B., Dufour S., Hadj-Slimane R., Gigoux V., Pethe S., L'hoste S., Camonis J., Garbay C., Raynaud F., Vidal M. only a selection of interactions described in this publication have been curated SH3 suggested by mcarducci Cell. Signal. (0898-6568) 2008 partial coverage mimix curation mimix curation Capns1, a new binding partner of RasGAP-SH3 domain in K-Ras(V12) oncogenic cells: modulation of cell survival and migration. Capns1, a new binding partner of RasGAP-SH3 domain in K-Ras(V12) oncogenic cells: modulation of cell survival and migration. Cell. Signal. (0898-6568) 2008 mimix curation Pamonsinlapatham P., Gril B., Dufour S., Hadj-Slimane R., Gigoux V., Pethe S., L'hoste S., Camonis J., Garbay C., Raynaud F., Vidal M. only a selection of interactions described in this publication have been curated SH3 suggested by mcarducci partial coverage mimix curation yeast Saccharomyces cerevisiae Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Pamonsinlapatham P., Gril B., Dufour S., Hadj-Slimane R., Gigoux V., Pethe S., L'hoste S., Camonis J., Garbay C., Raynaud F., Vidal M. only a selection of interactions described in this publication have been curated SH3 suggested by mcarducci Cell. Signal. (0898-6568) 2008 partial coverage mimix curation mimix curation Capns1, a new binding partner of RasGAP-SH3 domain in K-Ras(V12) oncogenic cells: modulation of cell survival and migration. Capns1, a new binding partner of RasGAP-SH3 domain in K-Ras(V12) oncogenic cells: modulation of cell survival and migration. Cell. Signal. (0898-6568) 2008 mimix curation Pamonsinlapatham P., Gril B., Dufour S., Hadj-Slimane R., Gigoux V., Pethe S., L'hoste S., Camonis J., Garbay C., Raynaud F., Vidal M. only a selection of interactions described in this publication have been curated SH3 suggested by mcarducci partial coverage mimix curation human-hct116 Human colon carcinoma HCT116 cells hct116 Human colon carcinoma line HCT116 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Pamonsinlapatham P., Gril B., Dufour S., Hadj-Slimane R., Gigoux V., Pethe S., L'hoste S., Camonis J., Garbay C., Raynaud F., Vidal M. only a selection of interactions described in this publication have been curated SH3 suggested by mcarducci Cell. Signal. (0898-6568) 2008 partial coverage mimix curation mimix curation cpns1_human Calpain small subunit 1 Calcium-dependent protease small subunit 1 Calcium-dependent protease small subunit Calpain regulatory subunit Calcium-activated neutral proteinase small subunit CAPNS1 CAPN4 CAPNS protein protein human Homo sapiens Human MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 17B87A8E47A90632 canc_drome Calpain-C CalpC CG3692 Calcium-activated neutral proteinase homolog C protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MASKYERILSDCRSKNVLWEDPDFPAVQSSVFYYQTPPFTFQWKRIMDLADSGSGAVAANSSAAPVFLNESAEFDVVPGKMGDRWLVSCLGLLSSLRNLFYRVVPADQTLASAHGVFRFRLWWCGEWVEVLVDDRLPTINGRLAFMQPQASNCFWAALLEKAIAKLHGSYEALKYGTRSDGLTDLLGGVVRQMPILSDNIRPQTLKELLTTTCIVTCLADKSATVAKKNLAERMPNGILVNVNYRLSSLDKVKTLMGDSVQLVCLKDTFSSKPFGEKTHFLGDWSPMSKTWERVSQVERARLIRQLGPGEFWLSFCDFVEIFSTMEVVYLDTETSNDEEMLKSRPLHWKMKMHQGQWKRGVTAGGCRNHESFHINPQLLISVQDEQDLVIALNQHTAVEPKVIGFTMYTWDGEYMLSECLQKDFFKNHVSYLNSDYGNTRHVSYHTHLEAGHYVLIPTTYEPAEEAHFTVRILGTGSFRLSCLETQTMILLDPFPALKSTDAERCGGPKVKSVCQYEPVYMQLADENKTINCFELHELLEACLPNDYIKGCANIDICRQVIALQDRSGSGRITFQQFKTFMVNLKSWQGVFKMYTKEKAGILRAERLRDALCDIGFQLSTDIMNCLIQRYIRKDGTLRLSDFVSAVIHLTTAFNQFHLKNYGQVNVIEVHLHDWIKSILSC 67B4FDD05122E9D3 q8ir23_drome D-RasGAP Dmel\CG9209 FBpp0073946 RAS-GAP RasGAP Vap p120RasGAP rasGap vap RasGap Dmel_CG9209 p120 RasGAP vap-RA CG9209 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MADLIHLGNIDVVIQKDKPGSPTGCSDDGNLAGLGGMTGLGGIMAPGGIDLGDLAQELDHDEFDGPHMLNGERPAIIAPPESEWYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGINHFRITAVCGDFYIGGRQFISLSDLVGYYTSCSDLLKRERLAIPVAPPEPVNDKKRVVAILPYTKMPETDELSFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVDDLDVSIDPNTVFPWFHPNCTKNEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHSLNHPVVNGIQPEFNQQYVVEKAAEKIYATLRECRDQIGLKKIKGIKHHGHLNKKSDKTTKWKQLYFALINDGSETQLCFYDNPKKTKPKGLIDLSCAYLYQCHDSLWERPYCFQIVERALPCLATVTYLCAPSQESYVEWINSLKAQCDSQLSRAQKKVSRLRELRCLNLHVLEAHRLPFKLVPHPYCSISLNQVKVGKTRVKIAPEPVWEEEFVLDDVPPDVVSLTITLISRGKRGKDSEVAELTIDLSSLKNGQETEGWYQLTGMTPMGEWGSLRLRMRYLDDLIMPCEEYSPLQQLLLESELYAVKALAELCHNDRVPLATALLRVFRQEKRETELIRMLCQAEVTRENETTTLFRGASLATTLMDLYMRTECSGFLQSAVSETVQRILESKQSAELNPTKMDVNDDACTNAEFLLQILDLVTQSIFTSPDACPRNVRFICSCLQKAVMAKWPTERLVRTRVVSGFIFLRLLCPALLNPRQFGLVSETPPMAATRSLVMVAKCLQNLANLIEFGGKEQYMEVVNPFILKNKERMIVFLDQLSSVNDPNQPLGMFVEQSTNLNSQDTGRELATLHHICVSHSQELHELSNILSIKKLVTVTDMLTKHKLKYREMIS B9041102FD6C6F57 rasa1_human Ras GTPase-activating protein 1 Ras p21 protein activator p120GAP RASA1 RASA GAP protein protein human Homo sapiens Human MMAAEAGSEEGGPVTAGAGGGGAAAGSSAYPAVCRVKIPAALPVAAAPYPGLVETGVAGTLGGGAALGSEFLGAGSVAGALGGAGLTGGGTAAGVAGAAAGVAGAAVAGPSGDMALTKLPTSLLAETLGPGGGFPPLPPPPYLPPLGAGLGTVDEGDSLDGPEYEEEEVAIPLTAPPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVPDTDEISFLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDGKEIYNTIRRKTKDAFYKNIVKKGYLLKKGKGKRWKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCNLRKSSPGTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSSHIPLKGIEPGSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLRIFLHEKLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMKATATQFVHHALKDSILKIMESKQSCELSPSKLEKNEDVNTNLTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELPDTTEHSRTDLSRDLAALHEICVAHSDELRTLSNERGAQQHVLKKLLAITELLQQKQNQYTKTNDVR DIP protein P20936 original sequence version: 136 DIP protein P20936 original sequence version: 182 C35B6567F5BC5370 vap-calpc 2 Calpain-C 5 unspecified role unspecified role prey prey binding site binding region binding-associated region binding region certain certain sequence position certain c-terminal c-terminal position c-term carboxy-terminus c-terminus c-term c-terminus carboxy-terminus c-terminal RasGap 6 unspecified role unspecified role bait bait tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain physical association physical association f1a f1b domino mint rasa1-calpc 2 Calpain-C 5 unspecified role unspecified role prey prey binding site binding region binding-associated region binding region certain certain sequence position certain c-terminal c-terminal position c-term carboxy-terminus c-terminus c-term c-terminus carboxy-terminus c-terminal RasGap 7 unspecified role unspecified role bait bait binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P20936:p.Trp317Lys mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain W K Tue Jul 12 10:07:58 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 18:14:59 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'trp317lys' Tue Jun 30 16:02:40 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Trp317Lys' physical association physical association f1b domino mint rasa1-capns1 3 capns1 4 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level RasGap 7 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role bait bait living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association f2a homomint mint the same interaction has also been detected in PANC10.05 cells. capns1-rasa1 3 RasGap 7 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level capns1 4 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role bait bait living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association homomint mint the same interaction has also been detected in PANC10.05 cells. f2b f4a capns1-rasa1-1 1 RasGap 7 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain capns1 4 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role bait bait living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association homomint domino mint the same interaction has also been detected in PANC10.05 cells. f2b f4a