UniProt UniProt http://www.uniprot.org Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans. Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans. Dev. Biol. (0012-1606) 2006 imex curation Aceto D., Beers M., Kemphues KJ. kjk1@cornell.edu 16-Oct-2008: Contacted by JYOTI. jyoti Only protein-protein interactions caeel-embryo Caenorhabditis elegans embryo embryo Embryo Defined as the development stage prior to the initiation of tissue differentiation. fluorescence imaging fluorescence microscopy fluorescence imaging tag visualisation tag visualisation Aceto D., Beers M., Kemphues KJ. kjk1@cornell.edu Accepted 2008-OCT-22 by JYOTI. 16-Oct-2008: Contacted by JYOTI. Dev. Biol. (0012-1606) 2006 jyoti Only protein-protein interactions imex curation Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans. Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans. Dev. Biol. (0012-1606) 2006 imex curation Aceto D., Beers M., Kemphues KJ. kjk1@cornell.edu 16-Oct-2008: Contacted by JYOTI. jyoti Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Aceto D., Beers M., Kemphues KJ. kjk1@cornell.edu Accepted 2008-OCT-22 by JYOTI. 16-Oct-2008: Contacted by JYOTI. Dev. Biol. (0012-1606) 2006 jyoti Only protein-protein interactions imex curation cdc42_caeel Cell division control protein 42 homolog cdc-42 R07G3.1 CDC42Ce protein protein caeel Caenorhabditis elegans MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVAPASFENVREKWVPEISHHCSKTPFLLVGTQVDLRDDPGMLEKLAKNKQKPVSTDVGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALDPPQQEKKKKCNIL 38B7C025CC0FCB70 kpc3_caeel Protein kinase C-like 3 F09E5.1 pkc-3 aPKC Atypical protein kinase C-3 protein protein caeel Caenorhabditis elegans MSSPTSLEEDGDIKLKTRFQGQVVVLYARPPLILDDFFALLKDACKQHKKQDITVKWIDEDGDPISIDSQMELDEAVRCLNSSQEAELNIHVFVGKPELPGLPCQGEDKTVYRRGARRWKKIYLYNGHRFQAKRLNRRIQCFICHDYIWGIGRQGFRCVDCRLCVHKKCHRHVRTHCGQALQGPNIIPMAPASGSLKGARSNTSSSTTRSGGGIDNGAFHEHEIESPGSTSHDASRAMNGNGSSKWAVSLNDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPPYHPAVESDRDLTHFDHQFTDELPQLSPDNPDVIARIDQSEFDGFEYVNPLQMSREDSV A92760E880DB11B8 par3_caeel Partitioning defective protein 3 par-3 F54E7.3 Abnormal embryonic partitioning of cytoplasm protein 3 protein protein caeel Caenorhabditis elegans MSASSTSSSSTSCPEGGEPSGSCKSSDEGESTLKKRMQQYGIASGYANSSISTLDRSQYQSLPLNGTRRVTVQFGRMKIVVPWKESDQTVGQLADAALLRYKKARGMANEDRIHVHRLECASDGGILDMDDVLEEVFDLNYDQILAITDEANGGSTTPTYSQIQKQQHHYAQPLPYARKFDGGPSTPIASAFGSVTVNHQAHRAASPYNVGFARSNSRDFAPQPTHSKERRDSVVEVSSFDQIPQSGLRVSTPKPSRQSEDVIDGKPMNQPILRSSLRTEASGSRTEEATPVKQSRVTLSPEVEKKLAEQDERKSERRKHYDKNPGRFARGSDRKSRITDALLDARDRIADQLESQNPAEETKSQMIRVKIDQGPMPGTSLVTFPPIPEKSENEKQLGIEVNAVFDESSELPGTSEPTKLSSVQIMKIEDGGRIAKDGRIRVGDCIVAIDGKPVDQMSIIRVRASISDLAAVTSRPVTLIINRSLESFLEQESSAKPIQSALQQANTQYIGHTTVVELIKSSNGFGFTVTGRETAKGERLFYIGTVKPYGVALGHLKSGDRLLEINGTPTGQWTQSEIVEKLKETMVGEKIKFLVSRVSQSAIMSTSASSENKENEETLKVVEEEKIPQKLPLPALMTPPVPKDTPALSPSGASRFEIVIPFINGSSSAGLGVSLKARVSKKSNGSKVDCGIFIKNVMHGGAAFKEGGLRVDDRIVGVEDIDLEPLDNREAQAALAKKLKEVGMISSNVRLTISRYNECNPGQISRDLSRITVDASSPSPSSRMSSHTAPDSLLPSPATRGTSSSGADSSHSRQSSASSAVPAVPARLTERDSIVSDGTSRNDESELPDSADPFNREGLGRKSLSEKRGMGAAADPQHIKLFQDIKHQRQNSAPTSSTQKRSKSQPRSSSQRNYRSPMKLVDLPTTAAASASTNSQNLDDSDMLNRRSQSMESINRPVESILRGTGQIPTGSSSKVQFMQAASPDQHPFPPGAALLRLKNEESRSRDKSRRKSMGNPFSAMRNFFGFGSKSRDASPEKTPTESVQLRSVERPKSIIDERNNGSSERAPPPLPPHQSQRRGSGGNVFVDYGEPYGLIPQYPHNTTSGYESYADSELYDRYAAHRYHPRGGPIIDEDEYIYRQQSTSGNSPINTSSYVNYGLPASNAYHVGSRIPPQTSSGSISKTSGAMRRVYPAEYDEDVAYHQQIPQQSTRYQQGSGSGRGNADYHHMFNSWFAYTGGGAVGAAPVIKSSYGSSPVRIAAASAIERGESFVVEPVSGSSASATDRRGRSTSSGAVASGSSSTGFQYAAKEKYADARSGKFNGGSTRLFIPRHGGGLSAAAFATNFGGEAYETRGGGAGGSPSQYRRRDQGPPHRFPQY 3B498E7652CFF17D par6_caeel Partitioning defective protein 6 T26E3.3 par-6 protein protein caeel Caenorhabditis elegans MSYNGSYHQNHHSTLQVKSKFDSEWRRFSIPMHSASGVSYDGFRSLVEKLHHLESVQFTLCYNSTGGDLLPITNDDNLRKSFESARPLLRLLIQRRGESWEEKYGYGTDSDKRWKGISSLMAQKPPKRSYSISNPEDFRQVSAIIDVDIVPEAHRRVRLCKHGQERPLGFYIRDGTSVRVTERGVVKVSGIFISRLVDGGLAESTGLLGVNDEVLEVNGIEVLGKTLDQVTDMMVANAHNLIITVKPANQRNTLSRGPSQQGTPNASEMSAATAAATGGIQRPMKMNGSSDGSYHPKQHDANDSDSGED 4247E7875124953B par6-pkc3-1 2 4 unspecified role unspecified role prey prey 6 unspecified role unspecified role bait bait physical association physical association Fig 1B par6-par3-1 2 5 unspecified role unspecified role prey prey 6 unspecified role unspecified role bait bait physical association physical association Fig 1B par6-cdc42-1 2 6 unspecified role unspecified role bait bait Q9NAN2:p.[Pro135Ala;Asp137Ala;Phe138Ala;Arg139Ala] mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain P A certain certain sequence position certain certain certain sequence position certain D A certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain R A Wed May 02 18:40:29 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro135ala,asp137ala,phe138ala,arg139ala' Tue Jun 30 18:35:13 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Pro135Ala;Asp137Ala;Phe138Ala;Arg139Ala]' Q9NAN2:p.[Val141Ala;Ser142Ala;Ile144Ala;Ile145Ala] mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain V A certain certain sequence position certain certain certain sequence position certain S A certain certain sequence position certain certain certain sequence position certain I A certain certain sequence position certain certain certain sequence position certain I A Wed May 02 19:34:47 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val141ala,ser142ala,ile144ala,ile145ala' Tue Jun 30 16:49:42 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Val141Ala;Ser142Ala;Ile144Ala;Ile145Ala]' 3 unspecified role unspecified role prey prey Q05062:p.Gln61Leu mutation mutation certain certain sequence position certain certain certain sequence position certain Q L Wed May 02 14:49:01 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln61leu' Tue Jun 30 15:49:26 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln61Leu' Q05062:p.Thr17Asn mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain T N Wed May 02 19:09:10 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr17asn' Tue Jun 30 16:09:33 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Thr17Asn' physical association physical association Fig 1B par6-cdc42-2 1 6 unspecified role unspecified role neutral component neutral component n-terminus cfp tag cyan fluorescent protein tag CFP cyan fluorescent protein cyan fluorescent protein CFP cfp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 3 unspecified role unspecified role neutral component neutral component n-terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q05062:p.Gln61Leu mutation mutation certain certain sequence position certain certain certain sequence position certain Q L Wed May 02 17:12:48 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln61leu' Tue Jun 30 17:38:44 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln61Leu' colocalization colocalization Fig 5