UniProt UniProt http://www.uniprot.org Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans. Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans. Development (0950-1991) 2005 imex curation Yoda A., Kouike H., Okano H., Sawa H. sawa@cdb.riken.jp 12-Oct-2007: Contacted by JYOTI. davet Only protein-protein interactions caeel Caenorhabditis elegans anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Yoda A., Kouike H., Okano H., Sawa H. sawa@cdb.riken.jp Accepted 2007-OCT-21 by DAVET. Development (0950-1991) 2005 davet Only protein-protein interactions imex curation med13_caeel Mediator of RNA polymerase II transcription subunit 13 let-19 K08F8.6 mdt-13 psa-7 Mediator complex subunit 13 Lethal protein 19 CeTRAP240 protein protein caeel Caenorhabditis elegans MSSAKDSDKDASRKMKLQKRPEWNNGGSLEDCISNVYALLELPGIKWKCYRTKPNAPRGVALTADFVLKAYSKCLLDGILCTWRRKPLPPTDNKETPKLTNFSNDAPKELWVFWYDDEPALLQKNCEGLDNDDELSSANQMNIVSYEVRTIIFKALHVVLERDLTKDGFVRFGRWFTVPYDARENYLHFTYPSHSPAIRFNFFVHGSSTICASVQAQRQPTLITLARRHLECKTKRVVVVVGPWSMRGQLVQDQIALLADPKIQESAEKEWNQWKDYLQMEEKEPENVSEERQKSPDSDPPAPPQTTRVLLADSSDEEQSQSFEAIDESKKDDIPQRLRWMYEPDYRQEKSKEETPEEKEKREQSREVRKQRRKLREERRKEVERQRTEVKNPDDYDSDVVTDEDVGEKEECVNNDVPKMVLLDIDGVRLLYPSKFLCVTIDEDRQMLESIGLKTNQQPPELQAQNRRPRNKLVVNVANPILSTMAVYQYCENERLISKENVPQKSATSGQLLPPLKEKFLNWKFTAKKYGCRGDVSCRHCAEAEYQGESDGQVILDVDRHNRFLKYGPYTENSIRWHKIRSRIQKKFDFHAYHKKHPIGPITPRKAGDSVKQTKQLSAVKRRRRARRERAQKKRRDKKRPTGSTRADSEDDSFRMDKLSQDDWANFEGEHPKGIPEIEVDKDFELHNDIKIPKVPNDDNYKPKSFLPITYLTNNVDNNDFESMPGDDDMSEERFNQIFKDKYNRWKPGMSRAEKIEHAHYQFDPSNQMTGSPREYHLKDLPKKIQKYESILPTPKGNKFFKGSICRKGLRGYDEICADQDEKEMMRKAKWLKKARRKVSKQQIKKAGQYHIDMQKQIVKRSLKRAIRKLKLTTKKDSQSKGTKQQKLVLLSYKKKKVDEKKFQQYLKEVENVLDKLDVNSFCKKNEKAGFSEKAIPSGYIIPDYESSIHCGMEEESDSEIDEPRHGLGEGTCGQYLEGESVDLADMEHHHNELPMEVTSIGHIRTVGEHIGPDGMLSPPASNEMPKGGPLSVGPPSIESQGLNQIYPTPPSVQMLLGDAAQAHSPVMHTKSRYAMNTLEDDVERIAVPGGVGSLVEIEADDIETKNMQKWSKLSNQSKLSKFIALSCKDPFLKSKKKKYDTPVTSKFKIENEPPSMSAELVYAPMVTRNFYSAPHRTFGTLAQKVVDKRPSQFAIPSTSTAAHPGLTTPMASIFQSPTMPPPHTPSPFSAGPMSHHPMGPPAYPGTPGSFPPTTPTYPGMTPRPGPNFGPPGPVYPNSQQMMGPGGYPPQMGMINSQRHFQNQQMYQQQMVRMQQMRQMGGPPGYGAPGVSPYQQVNAITSPAGFGMPPNGPSSVQRLNNFVNQSQFGPNNGHPTPPYGYMQQMIPQSPNFNQQYNGMGNQLMSPIHQHQFHQQQMVQQQQQQQMQMHRQQMQMQNQNMSQPFQPPTAQMLQMQQNEQMRIAFSTLSERDKAKFQKRQGQLRSGIMPKSLQPAVLKNLKNPPDANIPYMKQDALFRPPESNSLQGESLTIAIVLSDTLLDLHFDSVFDACPICSCSVSIRSRDIGMYITPHTVLYSTERGHTNMREHTTGPWSGFNVNSATNCTCGFSAIRHRYLSCCSGLFEEDADEATASEHAVAPVIPPLDYPKKSTARDMSWFDSKSVHDLALLDQIRQMAFSNSLGKAVSHMATIKEHNRNLAIAVDLGNDVTVPSEYILSHVDALELLMLGNSVLGPMKNTSIANQVASHNKFLGFFHPWGIQIANGMTELEASEWVDLLGVVTPTLEGSMKQARHIPAETPFELDGPMTWKQIVTKSNRGKPPADDEEDFSLPEPVPAIMRALTKEAIRAAPNIEQYYEQAGLGPVDQPKDVMYITVIPDDDDIYSRTVEFMDTLTRTYEKMRLGRHIPFPVSTGTATRFREAFKSCQSQFPFQEQQHLAYTNQTLRNMPQTLADTPDPVNSDPKVWSRRAKRKLDFEEELKLPEAGSETIDESDDDEENEEVSKEENNELIDSEDVMDEVPKGFYEREGILRVGAPMEPSRSPHTVTNTPEFDNMTKYLSDENGFVSRLRLYLQQMEDLVHFALSENPEAFDRRGYRYQLAVEGRLKRQKHKMDIIEERLRFEASKDFDEQSDRKEPLEENDPEITPGIVISNNPVESWIDDELEEKRQQRQKENEQYPPEAQQAPSPVPAGMIHIPETLSKEERAVQPTLEMILADPATVAPINAQNIVWKQRDTRVPNPFPSSNQPPVAFEAAGSPDTDAYSTLPHVIVVYVVNPFSYGPEGHSALHMRIAILAFIRAFNSIMCKIPYEKRPQLQLEIVGMEGMDNVAKPIPDYFNDAKIPFDLLNDRPIRVERPGESVQGELARSLSIAVYTHPRVFFPDVYKSASARCMTAFGPGSQLMNTINKIEALNKDSFARMAKRSKTTLDTMDMYRHPGMIQAQQSTEKKNYIAYRVPSNIAVLAPPPMVYQMDEKGKAIMNQLDEQTLFISYCLVGTDFLVATATDAQGKLIDNCISNIKPRRQSNQVYRYRNKTQILDGMGKLWSFILGIMASETKNWRLVVGRLGRIGHGEFRAWTHLLNKTSLLRYSGSLKDICGACRSMPSVIGTPAILSACLITLEPEPSIRIMPEFHDQELSTKKSFLFQTPGDLSCTHILTFPVGTEINLEVQDQTADTKADENWEFGDLDIMEGLDDGDTEIMKDLGLETPSSAAIRQTGGPSMFFSEDSSSIEIQNQPLASGYYISTAPAPELPAWFWATCPSAKRHSPVHLKSSLHIHISEVKNDDIAMESTKEKEKDKEKDEKDAHPLESRQTEEVLRHVLESYNALSWLNLNRQTGDRYSCLPIHIQHLLRLYHSVARLLA C035FBFE9121D1FA med23_caeel Mediator of RNA polymerase II transcription subunit 23 sur-2 F39B2.4 mdt-23 Mediator complex subunit 23 Mediator complex subunit sur-2 protein protein caeel Caenorhabditis elegans MTDKPGSAEDTIEMDDTCSPQFVQEVNRIKSQIKSLVEENHTRKFFRPLTSNIGDETAILRIQFNNMMSKMEEKEKQSLVKELIKMVHHVAEKNSPDRVFVGTNYERVVDQLLRYAHQKGAISTNLCAEGLIMTSDFRLCSRICQEKWKFINDCIPKIDYKGIRNILRYILESQLRRLPYSLSPEQVNEIRIVENVILHIVDRDSNLMPPLITLSEIMRGMPKQALMLPRLTEKLASLSVHFRPIADLSHVCGRGFVYPIPLHPSFYPLTSCWEEHGLNASNTIVQPHHTLPYRPEHTSTYLYTLYMILRQPLGKDSLHPPSKTKTKTNWEMLISVMICESMAEAESLPETEPIPRYQWDNIVNIVIYGITQHLLVPKTFFNVLKNLIKRCKYTRARDEVMWIVFQVVGSLSNLTRLDDAVTEIVELYNELFDGDVVWMGASDHPALFARFLAAAGTWMILEKDFADKMPPANETIKSHIKFIQDGVDNFDSSNTAMLAVLSNIYRTDTKMGKLIVPTLQQMLESIDDTKSLFELSYKRMAVNCFSAFPVEFMEALTFRSKKTLLIQCFQPLRSFSTVRLPSPAVFETVAKICESEDYEMAVKDMEHLAQRSLHVATAADRSSGEHQNVQAKDQCYFLFDFLVYRLPHLHAYSKYSSTVNALSYFTQHIPNNPQNHQIYRLMEQFLMRRWCWAGFHGCITAHTQMFGTSYKDNTMMRHMAYPKTFSVPDQYPFAINPEIFKMAIYSFLRAVKITAQDIAIEKTMFPTIINGFGWPEKSTSYFPKWALDAIKASDTSNAVNTEEILSDVRNTARMHTSLTPNQFVIRYGEDRDPATSHCMLAVLFHFAYNSVDSTYNITSEFYEVMEKKTPKEIVVMGNYLVDYIIADAKTQDCNEKTFKNIAKAAALLVFQFQVLRADRLLLSLIMHPATDEDALICIQIANEFILTPEFQERIRWYHQNVPKKDHFPTEYIKAIVKYHDAFPEFEACELVRSYDSSSNVHMPTYYGCLIERLLPIMDQYLHVALEQQGYKLNPQILQSVSMLYKFHAMPIHFMYSVLFTSHGLMSGPDAKSFVLAFATQIEECHLTEAFEKFNHQKSSREQLIMELIDRMSASLDFILTPPPFVAKDWKIAELSPGAQTLYLACIELMASPHSPETLVAAMINVMQMKPHARPFNIVNLTALLLTALPAAYSNALHDEFVAVFVNGETANLKFEEIVFDNYEESLLLNLPNRARTINVISQQYWLHCSLSLLNFFSHEYVPRILEHVKTEKDLWYTLRLVMPYLRRYYENWDTAKQMRSQRENFGPLHIVKLVFQKLGSMAEEGVEIVYEQHLCDLFYNCKYFFAGDFLRNTAITEFAKLPEKMRDRLKFYVSQSEPTAEQETPPEKEKSPEKEKEQEQEQHVKAHQPLESTPSVSSLPQMQHHLQQAPLLPSHQMMPPPQQHSSSLQHHLQHHTSTHQMMDTSQHQTIQQQSNHPTQQQLQHQIPNMSMHQQMGPQYPGAVFHHPSGPVGHVPMQYGMGHHMQQHPHLPHHQQMPAPMHTMNPMMQNMTPQQQYLYMQQLQQHQQHQQYMQQQQQHHHQHQQQPH A125FCA74922B11C med6_caeel Mediator of RNA polymerase II transcription subunit 6 mdt-6 med-6 Y57E12AL.5 Mediator complex subunit 6 CeMED6 c-MED6 protein protein caeel Caenorhabditis elegans MMPRMGPPAAARQDNPLHVSFRNPQWPPNFINKDNVLDYFCNQANAFYEMNSCNQQIRMQNIVNRTVEECLRTMPGIQYVLWYSQPPLFIICKQRRNNVTNVSPIAYYYVINGSVHQAPDMYSLVQSRLLGALEPLRNAFGEVTNYSRYNTAKGYYWEFKNKPNVKKREEEKKEDEEEKLEDRSTNFQKTRTMMLLNQLFSEMPAEDALEREEKEEVEEEEEETLKTEEPTTSTDEPKFAEPTARTTSKQ 4AFE17BA9BDE8511 med6-med13-1 1 4 unspecified role unspecified role prey prey 3 unspecified role unspecified role prey prey c-terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 2 unspecified role unspecified role bait bait c-terminus gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range association association Fig 6