MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands. Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands. J. Biol. Chem. (0021-9258) 1997 Chen HI., Einbond A., Kwak SJ., Linn H., Koepf E., Peterson S., Kelly JW., Sudol M. in vitro In vitro filter binding filter binding Filter overlay assay Filter overlay assay nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Chen HI., Einbond A., Kwak SJ., Linn H., Koepf E., Peterson S., Kelly JW., Sudol M. J. Biol. Chem. (0021-9258) 1997 Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands. Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands. J. Biol. Chem. (0021-9258) 1997 Chen HI., Einbond A., Kwak SJ., Linn H., Koepf E., Peterson S., Kelly JW., Sudol M. in vitro In vitro peptide array peptide array predetermined predetermined participant predetermined Chen HI., Einbond A., Kwak SJ., Linn H., Koepf E., Peterson S., Kelly JW., Sudol M. J. Biol. Chem. (0021-9258) 1997 wbp1_mouse WW domain-binding protein 1 Wbp1 protein protein mouse Mus musculus Mouse MARASSRNSSEEAWGSLQAPQQQQSPAASSLEGAIWRRAGTQTRALDTILYHPQQSHLLRELCPGVNTQPYLCETGHCCGETGCCTYYYELWWFWLLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPVPTGSLLDLRLLSAFKPPAYEDVVHHPGTPPPPYTVGPGYPWTTSSECTRCSSESSCSAHLEGTNVEGVSSQQSALPHQEGEPRAGLSPVHIPPSCRYRRLTGDSGIELCPCPDSSEGEPLKEARASASQPDLEDHSPCALPPDSVSQVPPMGLASSCGDIP 2A5C95D34D9D7520 yap1_human Transcriptional coactivator YAP1 YAP1 YAP65 Protein yorkie homolog Yes-associated protein YAP65 homolog protein protein human Homo sapiens Human MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAMTQDGEIYYINHKNKTTSWLDPRLDPRFAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQAMRNINPSTANSPKCQELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL DIP protein P46937 original sequence version: 143 DIP protein P46937 original sequence version: 98 DIP protein P46937-1 original sequence version: 110 DIP protein P46937 original sequence version: 149 DIP protein P46937 original sequence version: 153 DIP protein P46937 original sequence version: 157 DIP protein P46937 original sequence version: 160 DIP protein P46937 original sequence version: 122 DIP protein P46937 original sequence version: 124 6145F7049ED338AE yap1-wbp1-2 1 3 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain PROLINE RICH range MINT-3177412: original sequence: 170-179 : PAYEDVVHHPGTPPPPYTVGPGYPWTTSS gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 4 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P46937:p.Tyr188Phe mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:07:16 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 19:35:04 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr188phe' Tue Jun 30 15:45:47 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr188Phe' range MINT-3177762: original sequence: 188-188 : EMAKTSSGQRYFLNHIDQTT binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-3177406: original sequence: 171-204 : VPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR Stoichiometry: 1.0 direct interaction direct interaction F4A homomint mint yap1-wbp1-3 1 4 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-3177908: original sequence: 171-204 : VPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR P46937:p.Pro202Ala mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain P A Tue Jul 12 10:07:27 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 14:24:30 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro202ala' Tue Jun 30 20:26:09 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Pro202Ala' range MINT-3177911: original sequence: 202-202 : HIDQTTTWQDPRKAMLSQMN Stoichiometry: 1.0 3 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain PROLINE RICH range MINT-3177898: original sequence: 170-179 : PAYEDVVHHPGTPPPPYTVGPGYPWTTSS Stoichiometry: 1.0 direct interaction direct interaction F4A homomint mint yap1-wbp1-4 1 4 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-3178003: original sequence: 171-204 : VPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR P46937:p.His192Phe mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain H F Tue Jul 12 10:07:30 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 16:44:56 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'his192phe' Tue Jun 30 19:47:59 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.His192Phe' range MINT-3178006: original sequence: 192-192 : TSSGQRYFLNHIDQTTTWQD gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 3 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain PROLINE RICH range MINT-3177993: original sequence: 170-179 : PAYEDVVHHPGTPPPPYTVGPGYPWTTSS gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 direct interaction direct interaction F4A homomint mint yap1-wbp1-5 1 4 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified P46937:p.Trp199Phe mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain W F Tue Jul 12 10:50:12 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation disrupting' Wed May 02 17:21:50 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'trp199phe' Tue Jun 30 17:15:12 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Trp199Phe' range MINT-3178059: original sequence: 199-199 : FLNHIDQTTTWQDPRKAMLS binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-3178056: original sequence: 171-204 : VPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 3 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain PROLINE RICH range MINT-3178046: original sequence: 170-179 : PAYEDVVHHPGTPPPPYTVGPGYPWTTSS gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 direct interaction direct interaction F4A homomint mint wbp1-yap1-4 2 3 peptide synthesis peptide synthesis predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified undefined mutation mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain Wed Jul 06 17:44:20 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'mutation disrupting' 173 range MINT-3179126: original sequence: 173-173 : EDVVHHPGTPPPPYTVGPGY binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain PROLINE RICH range MINT-3178660: original sequence: 170-179 : PAYEDVVHHPGTPPPPYTVGPGYPWTTSS Stoichiometry: 1.0 4 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-3178678: original sequence: 171-204 : VPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 direct interaction direct interaction F7 F5 F6 homomint mint wbp1-yap1-5 2 3 peptide synthesis peptide synthesis predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified undefined mutation mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain Wed Jul 06 17:44:40 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'mutation disrupting' 174 range MINT-3179492: original sequence: 174-174 : DVVHHPGTPPPPYTVGPGYP binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain PROLINE RICH range MINT-3179489: original sequence: 170-179 : PAYEDVVHHPGTPPPPYTVGPGYPWTTSS Stoichiometry: 1.0 4 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-3179502: original sequence: 171-204 : VPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR Stoichiometry: 1.0 direct interaction direct interaction F7 F5 F6 homomint mint wbp1-yap1-6 2 3 peptide synthesis peptide synthesis predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain PROLINE RICH range MINT-3179558: original sequence: 170-179 : PAYEDVVHHPGTPPPPYTVGPGYPWTTSS undefined mutation mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain Wed Jul 06 17:46:07 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'mutation disrupting' 176 range MINT-3179561: original sequence: 176-176 : VHHPGTPPPPYTVGPGYPWT Stoichiometry: 1.0 4 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-3179551: original sequence: 171-204 : VPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 direct interaction direct interaction F7 F5 F6 homomint mint