IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Isolation and expression of cDNAs from rainbow trout (Oncorhynchus mykiss) that encode two novel basic helix-loop-Helix/PER-ARNT-SIM (bHLH/PAS) proteins with distinct functions in the presence of the aryl hydrocarbon receptor. Isolation and expression of cDNAs from rainbow trout (Oncorhynchus mykiss) that encode two novel basic helix-loop-Helix/PER-ARNT-SIM (bHLH/PAS) proteins with distinct functions in the presence of the aryl hydrocarbon receptor. J. Biol. Chem. (0021-9258) 1996 imex curation Pollenz RS., Sullivan HR., Holmes J., Necela B., Peterson RE. pollenzr@musc.edu Only protein-protein interactions in vitro In vitro anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Pollenz RS., Sullivan HR., Holmes J., Necela B., Peterson RE. pollenzr@musc.edu Accepted 2006-JUL-10 by ORCHARD. J. Biol. Chem. (0021-9258) 1996 Only protein-protein interactions imex curation ahr_mouse Aryl hydrocarbon receptor Ahr protein protein mouse Mus musculus Mouse MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQDLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPDSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGYQFIHAADMLHCAESHIRMIKTGESGMTVFRLFAKHSRWRWVQSNARLIYRNGRPDYIIATQRPLTDEEGREHLQKRSTSLPFMFATGEAVLYEISSPFSPIMDPLPIRTKSNTSRKDWAPQSTPSKDSFHPSSLMSALIQQDESIYLCPPSSPAPLDSHFLMGSVSKCGSWQDSFAAAGSEAALKHEQIGHAQDVNLALSGGPSELFPDNKNNDLYNIMRNLGIDFEDIRSMQNEEFFRTDSTAAGEVDFKDIDITDEILTYVQDSLNNSTLMNSACQQQPVTQHLSCMLQERLQLEQQQQLQQPPPQALEPQQQLCQMVCPQQDLGPKHTQINGTFASWNPTPPVSFNCPQQELKHYQLFSSLQGTAQEFPYKPEVDSVPYTQNFAPCNQPLLPEHSKSVQLDFPGRDFEPSLHPTTSNLDFVSCLQVPENQSHGINSQSTMVSPQAYYAGAMSMYQCQPGPQRTPVDQTQYSSEIPGSQAFLSKVQSRGIFNETYSSDLSSIGHAAQTTGHLHHLAEARPLPDITPGGFL DIP protein P30561 original sequence version: 90 DIP protein P30561 original sequence version: 94 AA1560FA83DDD03C arnt_oncmy Aryl hydrocarbon receptor nuclear translocator arnt protein protein oncmy Oncorhynchus mykiss (Rainbow trout) Salmo gairdneri MDSSIPDIPDDSLGLGAGGAQASSSACCAKRVNKRRAAPDFDDDDDGSKLFRCDDDGGGGDKERFARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGSGNTAADGTYKPSFLTDQELKHLILEAADGFLFVVSCESGRVVYVSDSLTPVLNQSQSDWLGSSLYDQLHPDDGDKLREQLSTAESNNTGRMLDLKTGTVKKEGQQSSVRMCMGARRSFICRMRCGSCPVEPMSMNRLNFLRSRNRNGLGPPKDGEPQYVVVHCTGYIKSWPPTGVNLTDEEADNILGSRYCLVAIGRLQVTSCPSDTDMNSISVPVEFISRHNCQGLFTFVDHRCMATVGYQPQELLGKNILELAHPEDQELLRDSFQQVVKLKGQVLSVMFRFLSKTRDWLWIRTSSFTFQNPFSEEIEYIICTNANVKQLQQQQAELGGGGRDGLYEAGQVTLPQMPVQAVTAAGTDHSKTMDKAEMHPSMYPNPDQAKFLPSTSAPGVPIYPQDNNNYTTANRSNDTYSRSVGMAPQMVQPSHSAGQVLAQMSRQNGAPPSNSSPLQGGAAVSWPGPAAGARPPFNNQQVVPQAGKALSPQFAMGSFVGGSSSSFGAMPTTAAPTPTMGANYPNINPRATLNTNGYDGLGSGQQFPSRAVEAVWPQWQGQQQAQNRAEQHPHTQNNQPDIFPDVLAMLDQPANFNNDDFEIPIYPSFNE 83F6EBE711EDEB82 ahr-arnt 1 3 unspecified role unspecified role prey prey region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined in vitro In vitro 2 unspecified role unspecified role bait bait mouse-hepa_1c1 Mus musculus hepatoma, BW7756; Derived from: Hepa-1cl, cloned from the Hepa-1 cell line hepa_1c1 mouse, C57L liver hepatoma, BW7756; Derived from: Hepa-1cl, cloned from the Hepa-1 cell line physical association physical association 7 These results indicate that both rtARNT proteins can associate with the mouse AHR The isoform B of ARNT P79832 interacts better than isofrom a P79831. Activation with TCDD resulted in marginal increase in interaction. rtARNTa and rtARNTb Form Heterodimers with Murine AHR ahr-arnt-5 1 3 unspecified role unspecified role prey prey region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined in vitro In vitro 2 unspecified role unspecified role bait bait mouse-hepa_1c1 Mus musculus hepatoma, BW7756; Derived from: Hepa-1cl, cloned from the Hepa-1 cell line hepa_1c1 mouse, C57L liver hepatoma, BW7756; Derived from: Hepa-1cl, cloned from the Hepa-1 cell line physical association physical association 7 The interaction with P79832 Arnt isoform b was stronger than that with P79831 Arnt isoform a. Activation with TCDD results in marginal increase in interaction. These results indicate that both rtARNT proteins can associate with the mouse AHR