MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Intrinsic regulation of the interactions between the SH3 domain of p85 subunit of phosphatidylinositol-3 kinase and the protein network of BCR/ABL oncogenic tyrosine kinase. Intrinsic regulation of the interactions between the SH3 domain of p85 subunit of phosphatidylinositol-3 kinase and the protein network of BCR/ABL oncogenic tyrosine kinase. Exp. Hematol. (0301-472X) 2005 Ren SY., Xue F., Feng J., Skorski T. Virus - Publications including interactions involving viral proteins no SH3 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Ren SY., Xue F., Feng J., Skorski T. Virus - Publications including interactions involving viral proteins no SH3 Exp. Hematol. (0301-472X) 2005 shc1_human SHC-transforming protein 1 SHC1 SHC SHCA Src homology 2 domain-containing-transforming protein C1 SHC-transforming protein A SHC-transforming protein 3 protein protein human Homo sapiens Human MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCSFFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL DIP protein P29353 original sequence version: 161 DIP protein P29353 original sequence version: 190 7EFA5CB185A548D1 grb2_human Growth factor receptor-bound protein 2 GRB2 ASH Adapter protein GRB2 SH2/SH3 adapter GRB2 Protein Ash protein protein human Homo sapiens Human MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 83A4B0BA1B248DC4 gab2_human GRB2-associated-binding protein 2 Growth factor receptor bound protein 2-associated protein 2 GRB2-associated binder 2 pp100 GAB2 KIAA0571 protein protein human Homo sapiens Human MSGGGDVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL 107623FD07D884C9 p85a_human Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 GRB1 Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha protein protein human Homo sapiens Human MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR DIP protein P27986 original sequence version: 181 DIP protein P27986 original sequence version: 184 DIP protein P27986-1 original sequence version: 135 DIP protein P27986 original sequence version: 135 DIP protein P27986-1 original sequence version: 145 DIP protein P27986-1 original sequence version: 147 DIP protein P27986 original sequence version: 191 B9DAD8416C33140F cbl_human E3 ubiquitin-protein ligase CBL Signal transduction protein CBL Proto-oncogene c-Cbl Casitas B-lineage lymphoma proto-oncogene RING finger protein 55 CBL CBL2 RNF55 RING-type E3 ubiquitin transferase CBL protein protein human Homo sapiens Human MAGNVKKSSGAGGGSGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERKAGSCQQGSGPAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREFVSISSPAHVAT DIP protein P22681 original sequence version: 173 DIP protein P22681 original sequence version: 128 DIP protein P22681 original sequence version: 145 DIP protein P22681 original sequence version: 150 DIP protein P22681 original sequence version: 191 DIP protein P22681 original sequence version: 91 DIP protein P22681 original sequence version: 139 1AA6BF67377322CA q13746_human protein protein human Homo sapiens Human MIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPPWPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDAEALQRPVASDFQPQG fragmentation type: fragment mint homomint 95378BC0E0532DB6 pik3r1-q13746 1 7 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 5 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 direct interaction direct interaction F2 homomint mint pik3r1-q13746-1 1 7 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed Stoichiometry: 1.0 5 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified P27986:p.Tyr12Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:23:53 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 17:39:54 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr12phe' Tue Jun 30 17:29:13 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr12Phe' range MINT-1487261: original sequence: 12-12 : SAEGYQYRALYDYKKEREED P27986:p.Tyr73Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:23:53 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 17:06:15 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr73phe' Tue Jun 30 16:52:33 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr73Phe' range MINT-1487265: original sequence: 73-73 : TGERGDFPGTYVEYIGRKKI undefined mutation mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:26:16 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'mutation decreasing ' range MINT-1487267: original sequence: 52-52 : FSDGQEARPEEIGWLNGYNE range MINT-1487268: original sequence: 55-55 : GQEARPEEIGWLNGYNETTG range MINT-1487269: original sequence: 72-72 : TTGERGDFPGTYVEYIGRKK binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1487258: original sequence: 3-79 : AEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIG tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P27986:p.Tyr14Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:23:59 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 18:23:17 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr14phe' Tue Jun 30 20:23:01 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr14Phe' range MINT-1487263: original sequence: 14-14 : EGYQYRALYDYKKEREEDID Stoichiometry: 1.0 physical association physical association F3 homomint mint pik3r1-cbl-1 1 6 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 5 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified P27986:p.Tyr73Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:59:17 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 17:55:22 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr73phe' Tue Jun 30 18:40:29 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr73Phe' range MINT-1487319: original sequence: 73-73 : TGERGDFPGTYVEYIGRKKI binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1487312: original sequence: 3-79 : AEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIG tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P27986:p.Tyr12Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:24:26 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 17:31:41 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr12phe' Tue Jun 30 15:35:58 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr12Phe' range MINT-1487315: original sequence: 12-12 : SAEGYQYRALYDYKKEREED P27986:p.Tyr14Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:23:09 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 17:16:37 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr14phe' Tue Jun 30 16:25:46 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr14Phe' range MINT-1487317: original sequence: 14-14 : EGYQYRALYDYKKEREEDID undefined mutation mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:25:25 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'mutation decreasing ' range MINT-1487321: original sequence: 52-52 : FSDGQEARPEEIGWLNGYNE range MINT-1487322: original sequence: 55-55 : GQEARPEEIGWLNGYNETTG range MINT-1487323: original sequence: 72-72 : TTGERGDFPGTYVEYIGRKK Stoichiometry: 1.0 physical association physical association F3 homomint mint pik3r1-shc1-2 1 5 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undefined mutation mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:24:11 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'mutation decreasing ' range MINT-1487345: original sequence: 52-52 : FSDGQEARPEEIGWLNGYNE range MINT-1487346: original sequence: 55-55 : GQEARPEEIGWLNGYNETTG range MINT-1487347: original sequence: 72-72 : TTGERGDFPGTYVEYIGRKK range MINT-1487348: original sequence: 73-73 : TGERGDFPGTYVEYIGRKKI P27986:p.Tyr14Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:21:32 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 20:28:25 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr14phe' Tue Jun 30 19:49:15 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr14Phe' range MINT-1487343: original sequence: 14-14 : EGYQYRALYDYKKEREEDID binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1487340: original sequence: 3-79 : AEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIG Stoichiometry: 1.0 2 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 physical association physical association F3 homomint mint pik3r1-gab2 1 4 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 5 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified P27986:p.Tyr14Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:22:11 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 14:26:41 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr14phe' Tue Jun 30 19:23:52 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr14Phe' range MINT-1487219: original sequence: 14-14 : EGYQYRALYDYKKEREEDID undefined mutation mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:23:26 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'mutation decreasing ' range MINT-1487221: original sequence: 52-52 : FSDGQEARPEEIGWLNGYNE range MINT-1487222: original sequence: 55-55 : GQEARPEEIGWLNGYNETTG range MINT-1487223: original sequence: 72-72 : TTGERGDFPGTYVEYIGRKK tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1487216: original sequence: 3-79 : AEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIG Stoichiometry: 1.0 physical association physical association F3 homomint mint pik3r1-grb2 1 5 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified P27986:p.Tyr12Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:08:25 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 19:58:34 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr12phe' Tue Jun 30 16:10:18 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr12Phe' range MINT-1487288: original sequence: 12-12 : SAEGYQYRALYDYKKEREED P27986:p.Tyr73Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:08:24 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 18:40:35 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr73phe' Tue Jun 30 19:23:04 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr73Phe' range MINT-1487292: original sequence: 73-73 : TGERGDFPGTYVEYIGRKKI binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1487285: original sequence: 3-79 : AEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIG undefined mutation mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain Wed Jul 06 17:04:48 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'mutation decreasing ' range MINT-1487294: original sequence: 52-52 : FSDGQEARPEEIGWLNGYNE range MINT-1487295: original sequence: 55-55 : GQEARPEEIGWLNGYNETTG range MINT-1487296: original sequence: 72-72 : TTGERGDFPGTYVEYIGRKK tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P27986:p.Tyr14Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:08:32 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 16:05:50 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr14phe' Tue Jun 30 18:17:18 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr14Phe' range MINT-1487290: original sequence: 14-14 : EGYQYRALYDYKKEREEDID Stoichiometry: 1.0 3 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 physical association physical association F3 homomint mint pik3r1-q13746-2 1 7 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed Stoichiometry: 1.0 5 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified undefined mutation mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain Wed Jul 06 17:04:40 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'mutation decreasing ' range MINT-1487365: original sequence: 55-55 : GQEARPEEIGWLNGYNETTG tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 physical association physical association F4 homomint mint pik3r1-cbl-2 1 6 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 5 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified undefined mutation mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:37:39 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'mutation decreasing ' range MINT-1487242: original sequence: 55-55 : GQEARPEEIGWLNGYNETTG tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P27986:p.Tyr14Phe mutation mutation certain certain sequence position certain certain certain sequence position certain Y F Tue Jul 12 10:18:02 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation' Wed May 02 19:54:08 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr14phe' Tue Jun 30 18:57:20 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr14Phe' range MINT-1487240: original sequence: 14-14 : EGYQYRALYDYKKEREEDID Stoichiometry: 1.0 physical association physical association F4 homomint mint