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        <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
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        <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>The Arabidopsis thaliana MEK AtMKK6 activates the MAP kinase AtMPK13.</fullName>
        </names>
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            <attribute name="publication title" nameAc="MI:1091">The Arabidopsis thaliana MEK AtMKK6 activates the MAP kinase AtMPK13.</attribute>
            <attribute name="journal" nameAc="MI:0885">FEBS Lett. (0014-5793)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2004</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
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            <attribute name="uniprot-dr-export">no</attribute>
            <attribute name="imex-exported"/>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
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        <hostOrganismList>
          <hostOrganism ncbiTaxId="559292">
            <names>
              <shortLabel>yeast</shortLabel>
              <fullName>Saccharomyces cerevisiae</fullName>
              <alias type="synonym" typeAc="MI:1041">Baker's yeast</alias>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>experimental interac</shortLabel>
            <fullName>experimental interaction detection</fullName>
            <alias type="synonym" typeAc="MI:1041">experimental interac</alias>
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        <participantIdentificationMethod>
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            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
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        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Melikant B., Giuliani C., Halbmayer-Watzina S., Limmongkon A., Heberle-Bors E., Wilson C.</attribute>
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      </experimentDescription>
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    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>mpk13_arath</shortLabel>
          <fullName>Mitogen-activated protein kinase 13</fullName>
          <alias type="gene name" typeAc="MI:0301">MPK13</alias>
          <alias type="orf name" typeAc="MI:0306">F24B9.3</alias>
          <alias type="locus name" typeAc="MI:0305">At1g07880</alias>
        </names>
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        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
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        <organism ncbiTaxId="3702">
          <names>
            <shortLabel>arath</shortLabel>
            <fullName>Arabidopsis thaliana (Mouse-ear cress)</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse-ear cress</alias>
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        </organism>
        <sequence>MEKREDGGILTYDGRYVMYNVLGNIFELSSKYIPPIEPIGRGAYGIVCCATNSETNEEVAIKKIANAFDNRVDAKRTLREIKLLSHMDHDNVIKIKDIIELPEKERFEDVYIVYELMDTDLHQIIRSTQTLTDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVLNTNCDLKICDFGLARTSNETEIMTEYVVTRWYRAPELLLNSSEYTGAIDIWSVGCIFMEILRRETLFPGKDYVQQLKLITELLGSPDDSDLDFLRSDNARKYVKQLPHVQKQSFREKFPNISPMALDLAEKMLVFDPSKRITVDEALKQPYLASLHEINEEPTCPTPFSFDFEETALDEQDIKELVWRESLHFKNM</sequence>
        <attributeList>
          <attribute name="crc64">88472CBA140DB739</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>m2k6_arath</shortLabel>
          <fullName>Mitogen-activated protein kinase kinase 6</fullName>
          <alias type="gene name" typeAc="MI:0301">MKK6</alias>
          <alias type="gene name synonym" typeAc="MI:0302">ANQ1</alias>
          <alias type="locus name" typeAc="MI:0305">At5g56580</alias>
          <alias type="orf name" typeAc="MI:0306">MIK19.2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Protein Arabidopsis NQK1 homolog</alias>
        </names>
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        <interactorType>
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            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
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          <names>
            <shortLabel>arath</shortLabel>
            <fullName>Arabidopsis thaliana (Mouse-ear cress)</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse-ear cress</alias>
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        <sequence>MVKIKSNLKQLKLSVPAQESPISSFLTASGTFHDGDFLLNQKGLRLTSDEKQSRQSDSKELDFEITAEDLETVKVIGKGSGGVVQLVRHKWVGKFFAMKVIQMNIQEEIRKQIVQELKINQASSQCPHVVVCYHSFYHNGAFSLVLEYMDRGSLADVIRQVKTILEPYLAVVCKQVLLGLVYLHNERHVIHRDIKPSNLLVNHKGEVKISDFGVSASLASSMGQRDTFVGTYNYMSPERISGSTYDYSSDIWSLGMSVLECAIGRFPYLESEDQQNPPSFYELLAAIVENPPPTAPSDQFSPEFCSFVSACIQKDPPARASSLDLLSHPFIKKFEDKDIDLGILVGTLEPPVNYLR</sequence>
        <attributeList>
          <attribute name="crc64">C95016C1DAE69CED</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4" imexId="IM-13901-1">
        <names>
          <shortLabel>mkk6-mpk13-1</shortLabel>
        </names>
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            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>monoclonal western</shortLabel>
                  <fullName>monoclonal antibody western blot</fullName>
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                  <fullName>unspecified role</fullName>
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              <participantIdentificationMethod>
                <names>
                  <shortLabel>nucleotide sequence</shortLabel>
                  <fullName>nucleotide sequence identification</fullName>
                  <alias type="go synonym" typeAc="MI:0303">sequence cloning</alias>
                  <alias type="synonym" typeAc="MI:1041">sequence cloning</alias>
                  <alias type="synonym" typeAc="MI:1041">nucleotide sequence</alias>
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              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
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                <fullName>enzyme</fullName>
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            <experimentalRoleList>
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                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
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                  <fullName>over expressed level</fullName>
                  <alias type="synonym" typeAc="MI:1041">over-expressed</alias>
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              <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
            </attributeList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>phosphorylation</shortLabel>
            <fullName>phosphorylation reaction</fullName>
            <alias type="synonym" typeAc="MI:1041">phosphorylation</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0217" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49922" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="resid" dbAc="MI:0248" id="AA0033" refType="see-also" refTypeAc="MI:0361"/>
            <secondaryRef db="resid" dbAc="MI:0248" id="AA0034" refType="see-also" refTypeAc="MI:0361"/>
            <secondaryRef db="resid" dbAc="MI:0248" id="AA0035" refType="see-also" refTypeAc="MI:0361"/>
            <secondaryRef db="resid" dbAc="MI:0248" id="AA0036" refType="see-also" refTypeAc="MI:0361"/>
            <secondaryRef db="resid" dbAc="MI:0248" id="AA0037" refType="see-also" refTypeAc="MI:0361"/>
            <secondaryRef db="resid" dbAc="MI:0248" id="AA0038" refType="see-also" refTypeAc="MI:0361"/>
            <secondaryRef db="resid" dbAc="MI:0248" id="AA0039" refType="see-also" refTypeAc="MI:0361"/>
            <secondaryRef db="resid" dbAc="MI:0248" id="AA0222" refType="see-also" refTypeAc="MI:0361"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="go" dbAc="MI:0448" id="GO:0016310" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F2</attribute>
          <attribute name="comment" nameAc="MI:0612">The authors show how MKK6 activates AtMPK13; kinase activity of AtMPK13 was measured by incubating the IP in kinase buffer containing myelin basic protein (MBP) - 81.208.106.64</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>