IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Self-assembling protein microarrays. Self-assembling protein microarrays. Science (0036-8075) 2004 Ramachandran N., Hainsworth E., Bhullar B., Eisenstein S., Rosen B., Lau AY., Walter JC., LaBaer J. Tyramide Signal Amplification system was used to determine interaction. Signal intensity of >0.049 was identified as an interaction. in vitro In vitro protein array protein array predetermined predetermined participant predetermined Ramachandran N., Hainsworth E., Bhullar B., Eisenstein S., Rosen B., Lau AY., Walter JC., LaBaer J. Tyramide Signal Amplification system was used to determine interaction. Signal intensity of >0.049 was identified as an interaction. The HA-tag on prey protein was detected using anti-HA antibodies, these were then detected using HRP conjugated secondary antibodies, which was developed using Tyramide Signal Amplification system. Signal intensity of >0.049 was identified as an interaction. Accepted 2010-JAN-10 by SKERRIEN (applied to all records created before 2005-Sep-01). Science (0036-8075) 2004 Self-assembling protein microarrays. Self-assembling protein microarrays. Science (0036-8075) 2004 Ramachandran N., Hainsworth E., Bhullar B., Eisenstein S., Rosen B., Lau AY., Walter JC., LaBaer J. Tyramide Signal Amplification system was used to determine interaction. Signal intensity of >0.049 was identified as an interaction. in vitro In vitro peptide array peptide array predetermined predetermined participant predetermined Ramachandran N., Hainsworth E., Bhullar B., Eisenstein S., Rosen B., Lau AY., Walter JC., LaBaer J. Tyramide Signal Amplification system was used to determine interaction. Signal intensity of >0.049 was identified as an interaction. Accepted 2010-JAN-10 by SKERRIEN (applied to all records created before 2005-Sep-01). Science (0036-8075) 2004 ccnb2_human G2/mitotic-specific cyclin-B2 CCNB2 protein protein human Homo sapiens Human MALLRRPTVSSDLENIDTGVNSKVKSHVTIRRTVLEEIGNRVTTRAAQVAKKAQNTKVPVQPTKTTNVNKQLKPTASVKPVQMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMIPQLNSKAVKDLASPLIGRS DIP protein O95067 original sequence version: 118 874466E1DD68A4C4 cdc6_human Cell division control protein 6 homolog CDC6 CDC18L CDC6-related protein p62(cdc6) Cdc18-related protein protein protein human Homo sapiens Human MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLGDDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDKALIGNILATGLP DIP protein Q99741 original sequence version: 102 3ED7DE4AF80CB017 mcm6_human DNA replication licensing factor MCM6 MCM6 p105MCM protein protein human Homo sapiens Human MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICRNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEYCRISNLIVLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRLTHYDHVLIELTQAGLKGSTEGSESYEEDPYLVVNPNYLLED DIP protein Q14566 original sequence version: 145 DIP protein Q14566 original sequence version: 98 DIP protein Q14566 original sequence version: 109 DIP protein Q14566 original sequence version: 150 F94968EB25A3E501 mcm4_human DNA replication licensing factor MCM4 MCM4 CDC21 CDC21 homolog P1-CDC21 protein protein human Homo sapiens Human MSSPASTPSRRGSRRGRATPAQTPRSEDARSSPSQRRRGEDSTSTGELQPMPTSPGVDLQSPAAQDVLFSSPPQMHSSAIPLDFDVSSPLTYGTPSSRVEGTPRSGVRGTPVRQRPDLGSAQKGLQVDLQSDGAAAEDIVASEQSLGQKLVIWGTDVNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLILSKGKTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTGKTVRLL DIP protein P33991 original sequence version: 121 DIP protein P33991 original sequence version: 165 DIP protein P33991 original sequence version: 168 96D9CA2A7D88D015 cdn1a_human Cyclin-dependent kinase inhibitor 1 CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 p21 CDK-interacting protein 1 Melanoma differentiation-associated protein 6 protein protein human Homo sapiens Human MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP DIP protein P38936 original sequence version: 120 DIP protein P38936 original sequence version: 165 DIP protein P38936 original sequence version: 160 98D1E7C519ADFCA9 cdk2_human Cyclin-dependent kinase 2 CDK2 p33 protein kinase Cell division protein kinase 2 CDKN2 protein protein human Homo sapiens Human MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL DIP protein P24941 original sequence version: 142 DIP protein P24941 original sequence version: 118 DIP protein P24941 original sequence version: 143 DIP protein P24941 original sequence version: 144 DIP protein P24941 original sequence version: 152 DIP protein P24941 original sequence version: 182 DIP protein P24941-1 original sequence version: 204 DIP protein P24941 original sequence version: 90 DIP protein P24941 original sequence version: 190 DIP protein P24941 original sequence version: 168 F90A0F4E70910B51 ccna1_human Cyclin-A1 CCNA1 protein protein human Homo sapiens Human METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ C9C023EEA1CF036D cdk4_human Cyclin-dependent kinase 4 CDK4 Cell division protein kinase 4 PSK-J3 protein protein human Homo sapiens Human MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE DIP protein P11802 original sequence version: 177 DIP protein P11802 original sequence version: 135 DIP protein P11802 original sequence version: 136 DIP protein P11802 original sequence version: 200 DIP protein P11802 original sequence version: 86 0916A0C07403A33A mcm5_human DNA replication licensing factor MCM5 MCM5 CDC46 CDC46 homolog P1-CDC46 protein protein human Homo sapiens Human MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRKVLYRLK DIP protein P33992 original sequence version: 126 A80280E61749998D cdk6_human Cyclin-dependent kinase 6 CDK6 Serine/threonine-protein kinase PLSTIRE Cell division protein kinase 6 CDKN6 protein protein human Homo sapiens Human MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA 571733EE6BE7FD4A orc2_human Origin recognition complex subunit 2 ORC2 ORC2L protein protein human Homo sapiens Human MSKPELKEDKMLEVHFVGDDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEYDLEEDDQEVLKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNLLSKVSPSFSAELKQLNQQYEKLFHKWMLQLHLGFNIVLYGLGSKRDLLERFRTTMLQDSIHVVINGFFPGISVKSVLNSITEEVLDHMGTFRSILDQLDWIVNKFKEDSSLELFLLIHNLDSQMLRGEKSQQIIGQLSSLHNIYLIASIDHLNAPLMWDHAKQSLFNWLWYETTTYSPYTEETSYENSLLVKQSGSLPLSSLTHVLRSLTPNARGIFRLLIKYQLDNQDNPSYIGLSFQDFYQQCREAFLVNSDLTLRAQLTEFRDHKLIRTKKGTDGVEYLLIPVDNGTLTDFLEKEEEEA DIP protein Q13416 original sequence version: 117 DIP protein Q13416 original sequence version: 56 DIP protein Q13416 original sequence version: 94 DF3F9C2CF147DA5F orc3_human Origin recognition complex subunit 3 ORC3 LATHEO Origin recognition complex subunit Latheo ORC3L protein protein human Homo sapiens Human MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQSLDETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC DIP protein Q9UBD5 original sequence version: 124 DIP protein Q9UBD5-1 original sequence version: 96 DIP protein Q9UBD5 original sequence version: 100 E713569A11B39B1C ccnd3_human G1/S-specific cyclin-D3 CCND3 protein protein human Homo sapiens Human MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL DIP protein P30281 original sequence version: 150 DIP protein P30281 original sequence version: 111 16E7B1604FEB0029 mcm10_human Protein MCM10 homolog MCM10 PRO2249 protein protein human Homo sapiens Human MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDVPALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGETTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVILKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMKPKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQYKKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPKKKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVVTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYKWERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK DD87191FFF3729D4 cdt1_human DNA replication factor Cdt1 Double parked homolog CDT1 protein protein human Homo sapiens Human MEQRRVTDFFARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELASCLQRARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQPGLPGLVLPYKYQVLAEMFRSMDTIVGMLHNRSETPTFAKVQRGVQDMMRRRFEECNVGQIKTVYPASYRFRQERSVPTFKDGTRRSDYQLTIEPLLEQEADGAAPQLTASRLLQRRQIFSQKLVEHVKEHHKAFLASLSPAMVVPEDQLTRWHPRFNVDEVPDIEPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPATPPATPPAASPSALKGVSQDLLERIRAKEAQKQLAQMTRCPEQEQRLQRLERLPELARVLRSVFVSERKPALSMEVACARMVGSCCTIMSPGEMEKHLLLLSELLPDWLSLHRIRTDTYVKLDKAADLAHITARLAHQTRAEEGL DIP protein Q9H211 original sequence version: 69 DIP protein Q9H211 original sequence version: 124 8179D0330C135FB7 mcm7_human DNA replication licensing factor MCM7 MCM7 CDC47 MCM2 CDC47 homolog P1.1-MCM3 protein protein human Homo sapiens Human MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDPELVDSICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVRSPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV DIP protein P33993 original sequence version: 161 DIP protein P33993 original sequence version: 124 330A1DEFAEFBFB88 mcm3_human DNA replication licensing factor MCM3 MCM3 DNA polymerase alpha holoenzyme-associated protein P1 RLF subunit beta p102 P1-MCM3 protein protein human Homo sapiens Human MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVALLDVFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQDDNQVMVSEGIIFLI DIP protein P25205 original sequence version: 135 DIP protein P25205 original sequence version: 179 C967C068B7090558 orc5_human Origin recognition complex subunit 5 ORC5 ORC5L protein protein human Homo sapiens Human MPHLENVVLCRESQVSILQSLFGERHHFSFPSIFIYGHTASGKTYVTQTLLKTLELPHVFVNCVECFTLRLLLEQILNKLNHLSSSEDGCSTEITCETFNDFVRLFKQVTTAENLKDQTVYIVLDKAEYLRDMEANLLPGFLRLQELADRNVTVLFLSEIVWEKFRPNTGCFEPFVLYFPDYSIGNLQKILSHDHPPEYSADFYAAYINILLGVFYTVCRDLKELRHLAVLNFPKYCEPVVKGEASERDTRKLWRNIEPHLKKAMQTVYLREISSSQWEKLQKDDTDPGQLKGLSAHTHVELPYYSKFILIAAYLASYNPARTDKRFFLKHHGKIKKTNFLKKHEKTSNHLLGPKPFPLDRLLAILYSIVDSRVAPTANIFSQITSLVTLQLLTLVGHDDQLDGPKYKCTVSLDFIRAIARTVNFDIIKYLYDFL DIP protein O43913 original sequence version: 116 DIP protein O43913 original sequence version: 53 DIP protein O43913 original sequence version: 90 0FEB0E829C124745 cdc5l_human Cell division cycle 5-like protein CDC5L Pombe cdc5-related protein KIAA0432 PCDC5RP protein protein human Homo sapiens Human MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEIARQTAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKETLKSKF DIP protein Q99459 original sequence version: 121 3390F91EE7E79DA6 orc6_human Origin recognition complex subunit 6 ORC6 ORC6L protein protein human Homo sapiens Human MGSELIGRLAPRLGLAEPDMLRKAEEYLRLSRVKCVGLSARTTETSSAVMCLDLAASWMKCPLDRAYLIKLSGLNKETYQSCLKSFECLLGLNSNIGIRDLAVQFSCIEAVNMASKILKSYESSLPQTQQVDLDLSRPLFTSAALLSACKILKLKVDKNKMVATSGVKKAIFDRLCKQLEKIGQQVDREPGDVATPPRKRKKIVVEAPAKEMEKVEEMPHKPQKDEDLTQDYEEWKRKILENAASAQKATAE DIP protein Q9Y5N6 original sequence version: 119 DIP protein Q9Y5N6 original sequence version: 56 DIP protein Q9Y5N6 original sequence version: 130 78840387605F45FE ccnd1_human G1/S-specific cyclin-D1 CCND1 BCL1 PRAD1 PRAD1 oncogene BCL-1 oncogene B-cell lymphoma 1 protein protein protein human Homo sapiens Human MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI DIP protein P24385 original sequence version: 163 DIP protein P24385 original sequence version: 165 DIP protein P24385 original sequence version: 160 DIP protein P24385 original sequence version: 121 DIP protein P24385 original sequence version: 122 DIP protein P24385 original sequence version: 143 DIP protein P24385 original sequence version: 127 3CC00C9905F58D3A orc1_human Origin recognition complex subunit 1 ORC1 ORC1L PARC1 Replication control protein 1 protein protein human Homo sapiens Human MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDDENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPACDSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAELLAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRAILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYALKDE DIP protein Q13415 original sequence version: 131 DIP protein Q13415 original sequence version: 64 DIP protein Q13415 original sequence version: 100 DIP protein Q13415 original sequence version: 105 5C594553F7F808E2 gemi_human Geminin GMNN protein protein human Homo sapiens Human MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTSTTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEETVEDSLVEDSEIGTCAEGTVSSSTDAKPCI DIP protein O75496 original sequence version: 78 DIP protein O75496 original sequence version: 117 DIP protein O75496 original sequence version: 136 0BABE60F6F5AC252 orc4_human Origin recognition complex subunit 4 ORC4 ORC4L protein protein human Homo sapiens Human MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGESNSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPNCPTDVRQWATSSLSWL DIP protein O43929 original sequence version: 134 DIP protein O43929 original sequence version: 65 A7020B6690E30B4E cdc45_human Cell division control protein 45 homolog CDC45 CDC45L2 UNQ374/PRO710 PORC-PI-1 CDC45L protein protein human Homo sapiens Human MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAFLEHKEQFHYFILINCGANVDLLDILQPDEDTIFFVCDTHRPVNVVNVYNDTQIKLLIKQDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEARRRDILFDYEQYEYHGTSSAMVMFELAWMLSKDLNDMLWWAIVGLTDQWVQDKITQMKYVTDVGVLQRHVSRHNHRNEDEENTLSVDCTRISFEYDLRLVLYQHWSLHDSLCNTSYTAARFKLWSVHGQKRLQEFLADMGLPLKQVKQKFQAMDISLKENLREMIEESANKFGMKDMRVQTFSIHFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYHGLELAKKQLRATQQTIASCLCTNLVISQGPFLYCSLMEGTPDVMLFSRPASLSLLSKHLLKSFVCSTKNRRCKLLPLVMAAPLSMEHGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRMLHNHFDLSVIELKAEDRSKFLDALISLLS DIP protein O75419 original sequence version: 88 DIP protein O75419 original sequence version: 96 DIP protein O75419 original sequence version: 135 AE1BE2C8C8E5F867 mcm2_human DNA replication licensing factor MCM2 MCM2 BM28 CDCL1 KIAA0030 Minichromosome maintenance protein 2 homolog Nuclear protein BM28 CCNL1 protein protein human Homo sapiens Human MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLVAEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMILQQF DIP protein P49736 original sequence version: 116 DIP protein P49736 original sequence version: 127 DIP protein P49736 original sequence version: 170 52C6DC61F128B404 cdc7_human Cell division cycle 7-related protein kinase CDC7 CDC7L1 protein protein human Homo sapiens Human MEASLGIQMDEPMAFSPQRDRFQAEGSLKKNEQNFKLAGVKKDIEKLYEAVPQLSNVFKIEDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTHDTKIELLKFVQSEAQQERCSQNKSHIITGNKIPLSGPVPKELDQQSTTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGERNFNIHSSISHESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVCSICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKTFGKSILCSKEVPAQDLRKLCERLRGMDSSTPKLTSDIQGHASHQPAISEKTDHKASCLVQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPDEAYDLLDKLLDLNPASRITAEEALLHPFFKDMSL DIP protein O00311 original sequence version: 127 90D549BEE20AE583 ccne2_human G1/S-specific cyclin-E2 CCNE2 protein protein human Homo sapiens Human MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPPVLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTHTNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH DIP protein O96020 original sequence version: 126 D7DC9BEEF3FD62EC cdn2a_human Cyclin-dependent kinase inhibitor 2A CDKN2A CDKN2 Cyclin-dependent kinase 4 inhibitor A p16-INK4a Multiple tumor suppressor 1 MTS1 protein protein human Homo sapiens Human MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD E59C0E6174B48255 cdt1-gmnn-1 2 25 unspecified role unspecified role prey prey in vitro In vitro 17 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction Bait is GST tagged while prey is HA tagged. Region of Cdt1 between AA198 and 212 necessary for interaction. Revisit when Protein editor in place. gmnn-cdt1 1 17 unspecified role unspecified role prey prey in vitro In vitro 25 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm2-orc6l 1 28 unspecified role unspecified role bait bait in vitro In vitro 22 unspecified role unspecified role prey prey in vitro In vitro direct interaction direct interaction orc1l-hscdc6 1 4 unspecified role unspecified role prey prey in vitro In vitro 24 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc1l-hscdc5 1 21 unspecified role unspecified role prey prey in vitro In vitro 24 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc1l-mcm5 1 11 unspecified role unspecified role prey prey in vitro In vitro 24 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm2-mcm3 1 19 unspecified role unspecified role prey prey in vitro In vitro 28 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc4l-mcm7 1 18 unspecified role unspecified role prey prey in vitro In vitro 26 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm5-mcm3 1 19 unspecified role unspecified role prey prey in vitro In vitro 11 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc6l-mcm6 1 5 unspecified role unspecified role prey prey in vitro In vitro 22 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc6l-orc4l 1 26 unspecified role unspecified role prey prey in vitro In vitro 22 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-orc4l 1 26 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc3l-orc5l 1 20 unspecified role unspecified role prey prey in vitro In vitro 14 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc6l-mcm4 1 6 unspecified role unspecified role prey prey in vitro In vitro 22 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-q9up68 1 27 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-mcm2 1 28 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm2-orc2l 1 13 unspecified role unspecified role prey prey in vitro In vitro 28 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc1l-cdt1 1 17 unspecified role unspecified role prey prey in vitro In vitro 24 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-mcm6 1 5 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm2-mcm5 1 11 unspecified role unspecified role prey prey in vitro In vitro 28 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-orc2l 1 16 unspecified role unspecified role bait bait in vitro In vitro 13 unspecified role unspecified role prey prey in vitro In vitro direct interaction direct interaction orc5l-cdc45l 1 27 unspecified role unspecified role prey prey in vitro In vitro 20 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm2-cdk6 1 12 unspecified role unspecified role prey prey in vitro In vitro 28 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc1l-orc5l 1 20 unspecified role unspecified role prey prey in vitro In vitro 24 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc1l-orc2l 1 13 unspecified role unspecified role prey prey in vitro In vitro 24 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc6l-cdc7 1 29 unspecified role unspecified role prey prey in vitro In vitro 22 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc4l-ccnd1 1 23 unspecified role unspecified role prey prey in vitro In vitro 26 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc3l-q9up68 1 27 unspecified role unspecified role prey prey in vitro In vitro 14 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-cdc7 1 29 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm3-orc5l 1 20 unspecified role unspecified role prey prey in vitro In vitro 19 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm3-hscdc5 1 21 unspecified role unspecified role prey prey in vitro In vitro 19 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-mcm3 1 19 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc4l-mcm3 1 26 unspecified role unspecified role bait bait in vitro In vitro 19 unspecified role unspecified role prey prey in vitro In vitro direct interaction direct interaction orc2l-hscdc5 1 21 unspecified role unspecified role prey prey in vitro In vitro 13 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-ccnd3 1 15 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm4-hscdc5 1 21 unspecified role unspecified role prey prey in vitro In vitro 6 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc2l-hscdc6 1 4 unspecified role unspecified role prey prey in vitro In vitro 13 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-hscdc5 1 21 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm2-ccnb2 1 3 unspecified role unspecified role prey prey in vitro In vitro 28 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm6-mcm6 1 5 unspecified role unspecified role prey prey in vitro In vitro 5 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-hscdc6 1 4 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-ccnd1 1 23 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc6l-orc3l 1 14 unspecified role unspecified role prey prey in vitro In vitro 22 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-mcm7 1 18 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc3l-ccne2 1 30 unspecified role unspecified role prey prey in vitro In vitro 14 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm2-mcm7 1 18 unspecified role unspecified role prey prey in vitro In vitro 28 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm7-orc3l 1 14 unspecified role unspecified role prey prey in vitro In vitro 18 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm2-orc5l 1 20 unspecified role unspecified role prey prey in vitro In vitro 28 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc5l-orc4l 1 26 unspecified role unspecified role prey prey in vitro In vitro 20 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc1l-orc3l 1 14 unspecified role unspecified role prey prey in vitro In vitro 24 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm2-hscdc6 1 4 unspecified role unspecified role prey prey in vitro In vitro 28 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdk6-cdkn2a 1 31 unspecified role unspecified role prey prey in vitro In vitro 12 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdk4-cdkn2a 1 31 unspecified role unspecified role prey prey in vitro In vitro 10 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm6-ccna1 1 9 unspecified role unspecified role prey prey in vitro In vitro 5 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn2a-gmnn 1 25 unspecified role unspecified role prey prey in vitro In vitro 31 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc3l-mcm5 1 11 unspecified role unspecified role prey prey in vitro In vitro 14 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc4l-cdkn2a 1 26 unspecified role unspecified role bait bait in vitro In vitro 31 unspecified role unspecified role prey prey in vitro In vitro direct interaction direct interaction orc4l-orc3l 1 14 unspecified role unspecified role prey prey in vitro In vitro 26 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc5l-mcm5 1 11 unspecified role unspecified role prey prey in vitro In vitro 20 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc2l-orc5l 1 20 unspecified role unspecified role prey prey in vitro In vitro 13 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm10-cdk6 1 12 unspecified role unspecified role prey prey in vitro In vitro 16 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-ccnd3 1 15 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm6-gmnn 1 25 unspecified role unspecified role prey prey in vitro In vitro 5 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction hscdc6-orc5l 1 20 unspecified role unspecified role prey prey in vitro In vitro 4 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc3l-hscdc6 1 4 unspecified role unspecified role prey prey in vitro In vitro 14 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc5l-orc5l 1 20 unspecified role unspecified role prey prey in vitro In vitro 20 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction hscdc6-orc6l 1 22 unspecified role unspecified role prey prey in vitro In vitro 4 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc3l-mcm10 1 16 unspecified role unspecified role prey prey in vitro In vitro 14 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc6l-mcm7 1 18 unspecified role unspecified role prey prey in vitro In vitro 22 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdk2-ccne2 1 30 unspecified role unspecified role prey prey in vitro In vitro 8 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn2a-hscdc6 1 4 unspecified role unspecified role prey prey in vitro In vitro 31 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdk4-ccnd3 1 15 unspecified role unspecified role prey prey region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined in vitro In vitro 10 unspecified role unspecified role bait bait region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined in vitro In vitro direct interaction direct interaction mcm2-cdk4 1 28 unspecified role unspecified role bait bait in vitro In vitro 10 unspecified role unspecified role prey prey in vitro In vitro direct interaction direct interaction cdk6-ccnd3 1 15 unspecified role unspecified role prey prey in vitro In vitro 12 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-ccne2 1 30 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn2a-orc5l 1 20 unspecified role unspecified role prey prey in vitro In vitro 31 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdk4-ccnd1 1 23 unspecified role unspecified role prey prey in vitro In vitro 10 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-cdc45l 1 27 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-hscdc6 1 4 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-cdc7 1 29 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdc7-orc5l 1 20 unspecified role unspecified role prey prey in vitro In vitro 29 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn2a-cdc45l 1 27 unspecified role unspecified role prey prey in vitro In vitro 31 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-ccnd1 1 23 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn2a-cdc7 1 29 unspecified role unspecified role prey prey in vitro In vitro 31 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm2-cdkn2a 1 31 unspecified role unspecified role prey prey in vitro In vitro 28 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdk6-ccnd1 1 23 unspecified role unspecified role prey prey in vitro In vitro 12 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm7-mcm5 1 11 unspecified role unspecified role prey prey in vitro In vitro 18 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn2a-mcm10 1 16 unspecified role unspecified role prey prey in vitro In vitro 31 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction hscdc5-cdt1 1 17 unspecified role unspecified role prey prey in vitro In vitro 21 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm3-cdc7 1 29 unspecified role unspecified role prey prey in vitro In vitro 19 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-hscdc5 1 21 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-cdk6 1 12 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc2l-orc4l 1 26 unspecified role unspecified role prey prey in vitro In vitro 13 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-ccnb2 1 3 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc2l-cdk2 1 8 unspecified role unspecified role prey prey in vitro In vitro 13 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn2a-mcm5 1 11 unspecified role unspecified role prey prey in vitro In vitro 31 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction hscdc6-cdt1 1 17 unspecified role unspecified role prey prey in vitro In vitro 4 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-cdk4 1 10 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm4-mcm7 1 18 unspecified role unspecified role prey prey in vitro In vitro 6 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm3-hscdc6 1 4 unspecified role unspecified role prey prey in vitro In vitro 19 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdk2-ccnb2 1 3 unspecified role unspecified role prey prey in vitro In vitro 8 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-ccna1 1 9 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm4-ccna1 1 9 unspecified role unspecified role prey prey in vitro In vitro 6 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction orc2l-cdt1 1 17 unspecified role unspecified role prey prey in vitro In vitro 13 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm3-cdk2 1 8 unspecified role unspecified role prey prey in vitro In vitro 19 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-cdk2 1 8 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-gmnn 1 25 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdkn1a-mcm10 1 16 unspecified role unspecified role prey prey in vitro In vitro 7 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction cdc7-cdk4 1 10 unspecified role unspecified role prey prey in vitro In vitro 29 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction mcm3-mcm6 1 5 unspecified role unspecified role prey prey in vitro In vitro 19 unspecified role unspecified role bait bait in vitro In vitro direct interaction direct interaction