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  <entry>
    <source releaseDate="2022-02-03">
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        <shortLabel>MINT</shortLabel>
        <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
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        <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity.</fullName>
        </names>
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            <attribute name="publication year" nameAc="MI:0886">2003</attribute>
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        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
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        <interactionDetectionMethod>
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            <shortLabel>pull down</shortLabel>
            <fullName>pull down</fullName>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>nucleotide sequence</shortLabel>
            <fullName>nucleotide sequence identification</fullName>
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          <attribute name="author-list" nameAc="MI:0636">Cavet ME., Lehoux S., Berk BC.</attribute>
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          <attribute name="publication year" nameAc="MI:0886">2003</attribute>
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        <names>
          <fullName>14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity.</fullName>
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          <hostOrganism ncbiTaxId="-3">
            <names>
              <shortLabel>unknown</shortLabel>
              <fullName>Unknown</fullName>
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            <shortLabel>pull down</shortLabel>
            <fullName>pull down</fullName>
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            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
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          <attribute name="author-list" nameAc="MI:0636">Cavet ME., Lehoux S., Berk BC.</attribute>
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      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="3">
        <names>
          <shortLabel>ks6a1_rat</shortLabel>
          <fullName>Ribosomal protein S6 kinase alpha-1</fullName>
          <alias type="gene name" typeAc="MI:0301">Rps6ka1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Rsk1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">90 kDa ribosomal protein S6 kinase 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Ribosomal S6 kinase 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">MAP kinase-activated protein kinase 1a</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Mapkapk1a</alias>
        </names>
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        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
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          <xref>
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        </interactorType>
        <organism ncbiTaxId="10116">
          <names>
            <shortLabel>rat</shortLabel>
            <fullName>Rattus norvegicus (Rat)</fullName>
            <alias type="synonym" typeAc="MI:1041">Rat</alias>
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        </organism>
        <sequence>MPLAQLKEPWPLMELVPLDPENGQASGEEAGLQPSKDEGILKEISITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDNGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTPRDSPGIPPSAGAHQLFRGFSFVATGLMEDDSKPRATQAPLHSVVQQLHGKNLVFSDGYIVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDSKHVYLVTELMRGGELLDKILRQKFFSEREASFVLYTISKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGYTPFANGPSDTPEEILTRISSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLPQSQLSHQDLQLVKGGMAATYSALSSSKPTPQLKPIESSILAQRRVRKLPSTTL</sequence>
        <attributeList>
          <attribute name="function" nameAc="MI:0613">Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
          <attribute name="crc64">12DEAD1E07140FDE</attribute>
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          <shortLabel>ks6a1_human</shortLabel>
          <fullName>Ribosomal protein S6 kinase alpha-1</fullName>
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          <alias type="gene name synonym" typeAc="MI:0302">MAPKAPK1A</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Ribosomal S6 kinase 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">MAP kinase-activated protein kinase 1a</alias>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441" version="SP_220"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017892" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043154" version="SP_220"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR041906" version="SP_220"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q15418" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2WNT" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043555" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043620" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z7Q" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z7R" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z7S" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RNY" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045202" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3TEI" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045597" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4H3P" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NIF" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CSF" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CSI" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CSJ" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CSN" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5N7D" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5N7F" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5N7G" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5V61" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5V62" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TWY" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198753" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-199920" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2559582" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-437239" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-442742" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-444257" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-881907" version="SP_220"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001006666.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002944.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001317370.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29987N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKDEGVLKEISITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQLSHQDLQLVKGAMAATYSALNSSKPTPQLKPIESSILAQRRVRKLPSTTL</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q15418 original sequence version: 111</attribute>
          <attribute name="remark-internal">DIP protein Q15418 original sequence version: 85</attribute>
          <attribute name="crc64">765731A4442A53DF</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>1433b_rat</shortLabel>
          <fullName>14-3-3 protein beta/alpha</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Protein kinase C inhibitor protein 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Prepronerve growth factor RNH-1</alias>
          <alias type="gene name" typeAc="MI:0301">Ywhab</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P35213" version="SP_71" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOP00000016981" version="SP_195" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-917309" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="rgd" dbAc="MI:0483" id="61998"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_062250.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOG00000010945" version="SP_195" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOT00000016981" version="SP_195" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004860" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006605" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008022" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0017053" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035308" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042470" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042826" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043085" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045744" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050815" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051219" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051220" version="SP_195"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000308" version="SP_195"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023409" version="SP_195"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023410" version="SP_195"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036815" version="SP_195"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P35213" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-111447" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-165159" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-166208" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-170968" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-2028269" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-392517" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-450385" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-450513" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-5625740" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-5628897" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-5673000" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-5674135" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-5675221" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-75035" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-9614399" version="SP_195"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10116">
          <names>
            <shortLabel>rat</shortLabel>
            <fullName>Rattus norvegicus (Rat)</fullName>
            <alias type="synonym" typeAc="MI:1041">Rat</alias>
          </names>
        </organism>
        <sequence>MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICSDVLELLDKYLILNATHAESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN</sequence>
        <attributeList>
          <attribute name="crc64">B663D1F2182F9C43</attribute>
        </attributeList>
      </interactor>
      <interactor id="6">
        <names>
          <shortLabel>1433b_human</shortLabel>
          <fullName>14-3-3 protein beta/alpha</fullName>
          <alias type="gene name" typeAc="MI:0301">YWHAB</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Protein kinase C inhibitor protein 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Protein 1054</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P31946" version="SP_94" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K9K2" version="SP_112" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E1P616" version="SP_127" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000300161" version="SP_235" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000361930" version="SP_235" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-359815" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003395.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_647539.1"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050815" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051219" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051220" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" version="SP_235"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000308" version="SP_235"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023409" version="SP_235"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023410" version="SP_235"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036815" version="SP_235"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P31946" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2BQ0" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C23" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DNK" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5N10" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6A5Q" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BYK" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GN0" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GN8" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GNJ" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GNK" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GNN" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6HEP" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111447" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1445148" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-165159" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166208" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-170968" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-170984" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2028269" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-392517" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-450385" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-450513" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5625740" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5628897" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5673000" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5674135" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5675221" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6802946" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6802948" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6802952" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6802955" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-75035" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9614399" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9649948" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9656223" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9660537" version="SP_235"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000166913" version="SP_235" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000353703" version="SP_235" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000372839" version="SP_235" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004860" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005774" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005925" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006605" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008022" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0017053" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035308" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042470" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042826" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043085" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045296" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045744" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" version="SP_235"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" version="SP_235"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016883528.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-743N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P31946 original sequence version: 171</attribute>
          <attribute name="remark-internal">DIP protein P31946 original sequence version: 97</attribute>
          <attribute name="remark-internal">DIP protein P31946 original sequence version: 119</attribute>
          <attribute name="remark-internal">DIP protein P31946 original sequence version: 122</attribute>
          <attribute name="remark-internal">DIP protein P31946 original sequence version: 180</attribute>
          <attribute name="crc64">6BE1A9BF97468017</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="7">
        <names>
          <shortLabel>ywhab-rps6ka1</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-19367" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8618348" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="8">
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-730010" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>6</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>nucleotide sequence</shortLabel>
                  <fullName>nucleotide sequence identification</fullName>
                  <alias type="go synonym" typeAc="MI:0303">sequence cloning</alias>
                  <alias type="synonym" typeAc="MI:1041">sequence cloning</alias>
                  <alias type="synonym" typeAc="MI:1041">nucleotide sequence</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0078" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-958" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <attributeList>
              <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
            </attributeList>
          </participant>
          <participant id="9">
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-730014" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>nucleotide sequence</shortLabel>
                  <fullName>nucleotide sequence identification</fullName>
                  <alias type="go synonym" typeAc="MI:0303">sequence cloning</alias>
                  <alias type="synonym" typeAc="MI:1041">sequence cloning</alias>
                  <alias type="synonym" typeAc="MI:1041">nucleotide sequence</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0078" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-958" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <attributeList>
              <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
            </attributeList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">domino</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
      <interaction id="10">
        <names>
          <shortLabel>rps6ka1-ywhab</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-8006350" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8618368" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="11">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">KS6A1_RAT</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-8006354" refType="identity" refTypeAc="MI:0356"/>
              <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q63531" refType="original identifier" refTypeAc="MI:0869"/>
            </xref>
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="12">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">1433B_RAT</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-8006351" refType="identity" refTypeAc="MI:0356"/>
              <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P35213" refType="original identifier" refTypeAc="MI:0869"/>
            </xref>
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>association</shortLabel>
            <fullName>association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="comment" nameAc="MI:0612">domino</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>