IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Structure of SARS-CoV-2 main protease in 1 the apo state reveals the 2 inactive conformation Structure of SARS-CoV-2 main protease in 1 the apo state reveals the 2 inactive conformation imex curation Xuelan Zhou, Fangling Zhong, Cheng Lin, Xiaohui Hu, Yan Zhang, Bing Xiong, Xiushan Yin, Jinheng Fu, Wei He, Jingjing Duan, Yang Fu, Huan Zhou, Qisheng Wang, Jian Li, Jin Zhang Virus - Publications including interactions involving viral proteins Coronavirus - Interactions investigated in the context of Coronavirus This entry has been curated from a pre-print and has not been peer-reviewed. If needed, the data in this entry will be amended once the manuscript has gone through peer-review zhangxiaokong@hotmail.com,rmsl_2040@163.com,wangqisheng@zjlab.org.cn 28-Sep-2020: Contacted by IntAct-Help. Only protein-protein interactions imex curation ecoli Escherichia coli (strain K12) x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Xuelan Zhou, Fangling Zhong, Cheng Lin, Xiaohui Hu, Yan Zhang, Bing Xiong, Xiushan Yin, Jinheng Fu, Wei He, Jingjing Duan, Yang Fu, Huan Zhou, Qisheng Wang, Jian Li, Jin Zhang Virus - Publications including interactions involving viral proteins This entry has been curated from a pre-print and has not been peer-reviewed. If needed, the data in this entry will be amended once the manuscript has gone through peer-review zhangxiaokong@hotmail.com,rmsl_2040@163.com,wangqisheng@zjlab.org.cn Accepted 2020-AUG-27 AT 11:03 BST AT 11:03 BST by LUANA Only protein-protein interactions imex curation imex curation p0dtd1-pro_0000449623 3C-like proteinase nsp5 rep ORF1ab polyprotein 1a-1b protein protein SARS-CoV-2 SARS-CoV-2 SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 2019-nCoV SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3264 3569 rep-115 1 2 unspecified role unspecified role neutral component neutral component purified purified n-terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range c-terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range direct interaction direct interaction Table 1 1.93Å Rwork: 0.23 Rfree: 0.27