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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>MINT</shortLabel>
        <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
        <alias type="synonym" typeAc="MI:1041">MINT</alias>
      </names>
      <bibref>
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      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0471" refType="identity" refTypeAc="MI:0356"/>
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      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
        <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
        <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
        <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
        <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>S-glutathionylation of IRF3 regulates IRF3-CBP interaction and activation of the IFN beta pathway.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="18309294" refType="primary-reference" refTypeAc="MI:0358"/>
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            <secondaryRef db="imex" dbAc="MI:0670" id="IM-11562" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">S-glutathionylation of IRF3 regulates IRF3-CBP interaction and activation of the IFN beta pathway.</attribute>
            <attribute name="journal" nameAc="MI:0885">EMBO J. (0261-4189)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2008</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Prinarakis E., Chantzoura E., Thanos D., Spyrou G.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Virus - Publications including interactions involving viral proteins</attribute>
            <attribute name="imex-exported">2009-01-08</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
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        </bibref>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6540708" refType="identity" refTypeAc="MI:0356"/>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human-293</shortLabel>
              <fullName>Homo sapiens transformed primary embryonal kidney cells</fullName>
              <alias type="synonym" typeAc="MI:1041">Human</alias>
            </names>
            <cellType>
              <names>
                <shortLabel>293</shortLabel>
                <fullName>Transformed human primary embryonal kidney cells.</fullName>
              </names>
              <xref>
                <primaryRef db="cabri" dbAc="MI:0246" id="ACC 305" refType="identity" refTypeAc="MI:0356"/>
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              </xref>
              <attributeList>
                <attribute name="comment" nameAc="MI:0612">The Cell type named 293 is synonymous with HEK-293.</attribute>
              </attributeList>
            </cellType>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti bait coip</shortLabel>
            <fullName>anti bait coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti bait coip</alias>
          </names>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
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            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
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        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Prinarakis E., Chantzoura E., Thanos D., Spyrou G.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Virus - Publications including interactions involving viral proteins</attribute>
          <attribute name="journal" nameAc="MI:0885">EMBO J. (0261-4189)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2008</attribute>
          <attribute name="imex-exported">2009-01-08</attribute>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959"/>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
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      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>gshb_human</shortLabel>
          <fullName>Glutathione synthetase</fullName>
          <alias type="gene name" typeAc="MI:0301">GSS</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Glutathione synthase</alias>
        </names>
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          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000169.1"/>
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        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKILSNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFEDISEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQLAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSRFVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVVQCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV</sequence>
        <attributeList>
          <attribute name="crc64">3C25EF7072EFE058</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>cbp_human</shortLabel>
          <fullName>CREB-binding protein</fullName>
          <alias type="gene name" typeAc="MI:0301">CREBBP</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CBP</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Histone lysine acetyltransferase CREBBP</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Protein-lysine acetyltransferase CREBBP</alias>
        </names>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LXS" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3DWY" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2N1A" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P1C" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P1D" version="SP_249"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001073315.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_004371.2"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P1E" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P1F" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2RNY" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6AY3" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6AY5" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6DMK" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ES5" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ES6" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ES7" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SQM" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FQO" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SXX" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIJ" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIK" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIL" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIM" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FQT" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7CO1" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7JFL" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7JFM" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1234158" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FQU" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1368082" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1368108" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1912408" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FR0" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FRF" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6M64" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QST" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1989781" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-201722" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-210744" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2122947" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2151201" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2426168" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2644606" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SQE" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SQF" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2894862" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3134973" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3214847" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3371568" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-350054" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-381340" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3899300" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-400206" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-400253" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5617472" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5621575" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6803204" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8866907" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8939246" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8941856" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013508" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013695" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9018519" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-918233" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-933541" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9614657" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SVH" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A9K" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N3W" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N4F" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NR4" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NR5" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NR6" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NR7" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NYV" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NYW" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NYX" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4OUF" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4TQN" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4TS8" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WHU" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4YK0" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CGP" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DBM" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5EIC" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5ENG" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5EP7" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GH9" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5H85" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5I83" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5I86" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5I89" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5I8B" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5I8G" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5J0D" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JEM" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KTU" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KTW" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KTX" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LPJ" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LPL" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MME" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MMG" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MPK" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MPN" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MPZ" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MQE" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MQG" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MQK" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5NLK" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5NRW" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5NU3" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OWK" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5SVH" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB6" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5W0E" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5W0F" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5W0L" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5W0Q" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5XXH" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ALB" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ALC" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6AXQ" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9707564" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9707616" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9617629" version="SP_249"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-952N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 134</attribute>
          <attribute name="remark-internal">DIP protein Q92793-1 original sequence version: 171</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 171</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 185</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 106</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 104</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 112</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 135</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 139</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 157</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 177</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 168</attribute>
          <attribute name="remark-internal">DIP protein Q92793-1 original sequence version: 174</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 146</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 161</attribute>
          <attribute name="remark-internal">DIP protein Q92793 original sequence version: 172</attribute>
          <attribute name="crc64">3BEA9B8558BA1A5E</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>irf3_human</shortLabel>
          <fullName>Interferon regulatory factor 3</fullName>
          <alias type="gene name" typeAc="MI:0301">IRF3</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q14653" version="SP_95" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5FBY1" version="SP_117" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5FBY2" version="SP_128" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q7Z5G6" version="SP_128" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K7L2" version="SP_95" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B2RAZ3" version="SP_139" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000310127" version="SP_205" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000366344" version="SP_205" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000469113" version="SP_205" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5FBY4" version="SP_130" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2650369" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001562.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001184053.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000126456" version="SP_205" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000309877" version="SP_205" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000377139" version="SP_205" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000597198" version="SP_205" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001227" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002376" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006974" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031663" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032481" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032727" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032728" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035666" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0039530" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042981" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050727" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051607" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060337" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060340" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071360" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071888" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097300" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0098586" version="SP_205"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990837" version="SP_205"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001346" version="SP_205"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008984" version="SP_205"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017855" version="SP_205"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019471" version="SP_205"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019817" version="SP_205"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036388" version="SP_205"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036390" version="SP_205"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q14653" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1J2F" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1QWT" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1T2K" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1ZOQ" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2O61" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2O6G" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2PI0" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3A77" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3QU6" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JEJ" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JEK" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JEL" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JEM" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JEO" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JER" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SIV" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SJA" version="SP_205"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7JFL" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1169408" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1606341" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-168928" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3134975" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3270619" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-877300" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3134973" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013973" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-909733" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-918233" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-933541" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-936440" version="SP_205"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-936964" version="SP_205"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001184051.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001184052.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001184054.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001184055.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001184056.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001184057.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006723260.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006723261.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016882255.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016882256.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-41448N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMDFQGPGES</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q14653 original sequence version: 96</attribute>
          <attribute name="remark-internal">DIP protein Q14653 original sequence version: 75</attribute>
          <attribute name="remark-internal">DIP protein Q14653 original sequence version: 95</attribute>
          <attribute name="remark-internal">DIP protein Q14653-1 original sequence version: 128</attribute>
          <attribute name="remark-internal">DIP protein Q14653 original sequence version: 119</attribute>
          <attribute name="crc64">F536676FA78B0110</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>g3p_human</shortLabel>
          <fullName>Glyceraldehyde-3-phosphate dehydrogenase</fullName>
          <alias type="gene name" typeAc="MI:0301">GAPDH</alias>
          <alias type="orf name" typeAc="MI:0306">OK/SW-cl.12</alias>
          <alias type="orf name" typeAc="MI:0306">CDABP0047</alias>
          <alias type="gene name synonym" typeAc="MI:0302">GAPD</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Peptidyl-cysteine S-nitrosylase GAPDH</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P04406" version="SP_118" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P00354" version="SP_118" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53X65" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E7EUT4" version="SP_182" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000229239" version="SP_259" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000380068" version="SP_259" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000380070" version="SP_259" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-354056" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002037.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001243728.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001276674.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001276675.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-32521N"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031965" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031982" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032481" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035605" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035606" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043231" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050661" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050821" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050832" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051287" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051402" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051873" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061844" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071346" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097452" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097718" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990904" version="SP_259"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006424" version="SP_259"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020828" version="SP_259"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020829" version="SP_259"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020830" version="SP_259"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020831" version="SP_259"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036291" version="SP_259"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P04406" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1U8F" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1ZNQ" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FEH" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3GPD" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WNC" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WNI" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ADE" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6M61" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YND" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YNE" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YNF" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YNH" version="SP_259"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-70171" version="SP_259"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-70263" version="SP_259"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6IQ6" version="SP_259"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000111640" version="SP_259" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000229239" version="SP_259" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000396859" version="SP_259" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000396861" version="SP_259" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000226" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001819" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004365" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005811" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006006" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006096" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008017" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010951" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015630" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016241" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0017148" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019828" version="SP_259"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031640" version="SP_259"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P04406 original sequence version: null</attribute>
          <attribute name="remark-internal">DIP protein P04406 original sequence version: 196</attribute>
          <attribute name="remark-internal">DIP protein P04406 original sequence version: 198</attribute>
          <attribute name="remark-internal">DIP protein P04406 original sequence version: 156</attribute>
          <attribute name="crc64">C9C135E8AE3E8744</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="6" imexId="IM-11562-1">
        <names>
          <shortLabel>irf3-gss</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6540711" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7830827" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-11562-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="7">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">IRF3</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6540713" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="8">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">GSH</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6540714" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>2</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F5A F5D F9D</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
      <interaction id="9" imexId="IM-11562-2">
        <names>
          <shortLabel>gapdh-gss</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6540721" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7830840" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-11562-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="10">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">GSH</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6540723" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>2</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="11">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">GAPDH</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6540725" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>5</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F5C</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
      <interaction id="12" imexId="IM-11562-3">
        <names>
          <shortLabel>crebbp-irf3-3</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6540731" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7830896" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-11562-3" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="13">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">IRF3</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6540733" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="14">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">CBP</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6540735" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>3</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F9A F9B F9C</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>