MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it ADP-ribosylation factor 6 and a functional PIX/p95-APP1 complex are required for Rac1B-mediated neurite outgrowth. ADP-ribosylation factor 6 and a functional PIX/p95-APP1 complex are required for Rac1B-mediated neurite outgrowth. Mol. Biol. Cell (1059-1524) 2003 Albertinazzi C., Za L., Paris S., de Curtis I. Virus - Publications including interactions involving viral proteins suggested by aryamontry in vitro In vitro pull down pull down predetermined predetermined participant predetermined Albertinazzi C., Za L., Paris S., de Curtis I. Virus - Publications including interactions involving viral proteins suggested by aryamontry Mol. Biol. Cell (1059-1524) 2003 ADP-ribosylation factor 6 and a functional PIX/p95-APP1 complex are required for Rac1B-mediated neurite outgrowth. ADP-ribosylation factor 6 and a functional PIX/p95-APP1 complex are required for Rac1B-mediated neurite outgrowth. Mol. Biol. Cell (1059-1524) 2003 Albertinazzi C., Za L., Paris S., de Curtis I. Virus - Publications including interactions involving viral proteins suggested by aryamontry chick-neuron Chick neuron neuron Neuron [Neuronal cell; Neural cell fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Albertinazzi C., Za L., Paris S., de Curtis I. Virus - Publications including interactions involving viral proteins suggested by aryamontry Mol. Biol. Cell (1059-1524) 2003 q6lc82_chick cRac1A RAC1 protein protein chick Gallus gallus (Chicken) Chicken MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL mint ACEDF83A45E5EA67 arhg6_chick Rho guanine nucleotide exchange factor 6 ARHGEF6 RCJMB04_5b15 Rac/Cdc42 guanine nucleotide exchange factor 6 protein protein chick Gallus gallus (Chicken) Chicken MNPEEQVVTWLISLGVLNSPKKIVDDPEEFLKTSLKDGTVLCKLIHRLLPGSAEKYCLEPKNEADCISNIQEFLRGCAVLKVELFEPHDLYSGEQFSKVLSTLTAVNKATEDQPSEGPCSHPSALSSAAGGAHTDSNSTASQSAKEMTENGSHQLVVKARFNFKQTNEDELSVNKGDIIYVTRVEEGGWWEGTLNGKTGWFPSNYVREIKSTDKPLSPKALKGLESTQLTKNYYPVVLQNILETERDYAKELQSLLGTYLRPLQSYDKLSAVDIASLLGNVEEISAFQQTLNQALEDVAKLPENQQRVGGCFMNLMAQFRSLYLTYCANHPSAVSVLTQHSDELEKFMESQGAANPGILILTTSLSKPFLRLDKYVTLLQELERHMEEAHADHEDVLKAITSFKSLVSQCQELRKRKQLELQILSESIQRWEGEDIKTMGNIIYMSQVMVQSGGSEEKEERYFLLFSNVLLMLSASPRMSGFIYQGRLPLTGMTLTKLEDAEGNEHMFEIAGNMMERITVSCSTSQDLHEWLEHLQRLTKGTCNTVSKTQSWSAHSTFGSTGQIRGPLEPPKILKPWSLSCLRPAPPLRPSAALSYKERMSYILKDSSKSPKTMKKFLPKRKTERKASDEEFVIRKSTAALEEDAQILKVIEAYCTGAGFQQALSSGSRKDSIPQVLLPEEEKIIIEETRSNGQTVTEEKSLVDTVYALKDEVKELKQENKRMKQCLEEELKSRKDLEKLVRRLLKQTDECSREETGRKSSLIA Acts as a RAC1 guanine nucleotide exchange factor (GEF) mint 3DF41DBE90259847 paxi_chick Paxillin PXN protein protein chick Gallus gallus (Chicken) Chicken MDDLDALLADLESTTSHISKRPVFLTEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTVIDPLDQWQPSVSRYGHQQPQSQSPIYSSSAKSSSASVPRDGLSSPSPRASEEEHVYSFPNKQKSAEPSPTMTSTSLGSNLSELDRLLLELNAVQHNPPSGFSADEVSRSPSLPNVTGPHYVIPESSSSAGGKAAPPTKEKPKRNGGRGIEDVRPSVESLLDELESSVPSPVPAITVSQGEVSSPQRVNASQQQTRISASSATRELDELMASLSDFKFMAQGKAGGSSSPPSTTPKPGSQLDTMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGVFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFINGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMGKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC 6450270D90B2DE84 arf6_chick ADP-ribosylation factor 6 ARF6 CPS1 protein protein chick Gallus gallus (Chicken) Chicken MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNYKS GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus mint 49E68E09AEA52B98 q9dg15_chick protein protein chick Gallus gallus (Chicken) Chicken MSRKAQRAEVCADCSAADPGWASINRGVLICDECCSVHRSLGRHISIVKHLRHSPWPATLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPTKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQILQAELLVVYGADPGAPDVNGRTPIDYARQAAQHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLTTQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLLIDILGEAKRRQQGKSPLSPTDALDYSLRSQSDLDDQHDYDSVASDEDTDQELLRNASRNNRARSMDSSDLSDGPITLQEYLEVKKALAASEAKVQQLMKVNNSLSDELRRLQREIHKLQSENTQIRQQAVPPHPTPAPSERPEHGHPPGTAPLHRRDRQAFSMYEPGSVLKPFGQPVEELVTRLQPFGGGMRKGPSVSSMPFPPSSPLLSCPPDGARHMSKLDRHGSGTDSDYDNTQTGEILLGVEGKRFVELSKDEDFPHELDPLDGELDPGLPSTEDVILKTEQVTKNIQELLRAAQESKHDSFVPCSEKIHSAVTEMASLFPKKPALETVRSSLRLLNASAYRLQSECRKTVPPEPGAAVDYQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ mint 483AD23F2AC795BB arf5_chick ADP-ribosylation factor 5 ARF5 CPS3 protein protein chick Gallus gallus (Chicken) Chicken MGLTVSAIFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESAEELQKMLQEDELRDAVLLVFANKQDMPNAMVVSELTDKLGLQALRSRTWYVQATCATQGTGLYDGLDWLSHELSKR GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus mint 846E785B55163415 arf5-arf6-1 2 Arf6 6 immunostaining immunostaining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell Arf5 8 immunostaining immunostaining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell p95-N 7 immunostaining immunostaining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell colocalization colocalization F6 mint arf6-q9dg15 2 p95-C2 7 immunostaining immunostaining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-6825970: original sequence: 229-740 : RLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLTTQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLLIDILGEAKRRQQGKSPLSPTDALDYSLRSQSDLDDQHDYDSVASDEDTDQELLRNASRNNRARSMDSSDLSDGPITLQEYLEVKKALAASEAKVQQLMKVNNSLSDELRRLQREIHKLQSENTQIRQQAVPPHPTPAPSERPEHGHPPGTAPLHRRDRQAFSMYEPGSVLKPFGQPVEELVTRLQPFGGGMRKGPSVSSMPFPPSSPLLSCPPDGARHMSKLDRHGSGTDSDYDNTQTGEILLGVEGKRFVELSKDEDFPHELDPLDGELDPGLPSTEDVILKTEQVTKNIQELLRAAQESKHDSFVPCSEKIHSAVTEMASLFPKKPALETVRSSLRLLNASAYRLQSECRKTVPPEPGAAVDYQLLTQQVIQCAYDIAKAAKQLVTITTREKK Arf6 6 immunostaining immunostaining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell colocalization colocalization F7 mint crac1a-arhgef6 1 p95 7 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey cell lysate cell lysate physiological level physiological level endogenous level endogenous endogenous endogenous level Rac1B 3 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined PIX 4 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey cell lysate cell lysate physiological level physiological level endogenous level endogenous endogenous endogenous level Paxillin 5 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey cell lysate cell lysate physiological level physiological level endogenous level endogenous endogenous endogenous level association association F1B homomint mint arhgef6-q9dg15 1 PIX 4 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified p95 7 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role prey prey cell lysate cell lysate physiological level physiological level endogenous level endogenous endogenous endogenous level gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association F3A mint