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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>IntAct</shortLabel>
        <fullName>European Bioinformatics Institute</fullName>
        <alias type="synonym" typeAc="MI:1041">IntAct</alias>
        <alias type="synonym" typeAc="MI:1041">intact</alias>
      </names>
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      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
        <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
        <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
        <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Candida tropicalis expresses two mitochondrial 2-enoyl thioester reductases that are able to form both homodimers and heterodimers.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="12890667" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1989686" refType="identity" refTypeAc="MI:0356"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Candida tropicalis expresses two mitochondrial 2-enoyl thioester reductases that are able to form both homodimers and heterodimers.</attribute>
            <attribute name="journal" nameAc="MI:0885">J. Biol. Chem. (0021-9258)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2003</attribute>
            <attribute name="author-list" nameAc="MI:0636">Torkko JM., Koivuranta KT., Kastaniotis AJ., Airenne TT., Glumoff T., Ilves M., Hartig A., Gurvitz A., Hiltunen JK.</attribute>
            <attribute name="dataset" nameAc="MI:0875">PDBe - Data obtained from the Protein Data Bank Europe</attribute>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="12890667" refType="primary-reference" refTypeAc="MI:0358"/>
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        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
          </names>
          <xref>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Torkko JM., Koivuranta KT., Kastaniotis AJ., Airenne TT., Glumoff T., Ilves M., Hartig A., Gurvitz A., Hiltunen JK.</attribute>
          <attribute name="dataset" nameAc="MI:0875">PDBe - Data obtained from the Protein Data Bank Europe</attribute>
          <attribute name="accepted"/>
          <attribute name="journal" nameAc="MI:0885">J. Biol. Chem. (0021-9258)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2003</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>etr2_cantr</shortLabel>
          <fullName>Enoyl-[acyl-carrier-protein] reductase 2, mitochondrial</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">2-enoyl thioester reductase 2</alias>
          <alias type="gene name" typeAc="MI:0301">ETR2</alias>
        </names>
        <xref>
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          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1036916" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011032"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H0K"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1N9G"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020843"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" version="SP_89"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006631" version="SP_89"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006633" version="SP_89"/>
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        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="5482">
          <names>
            <shortLabel>cantr</shortLabel>
            <fullName>Candida tropicalis (Yeast)</fullName>
          </names>
        </organism>
        <sequence>MYSVLKQSIRPRLLATHNQFRTMITAQAVLYTQHGEPKDVLFTQSFEIDDDNLAPNEVIVKTLGSPINPSDINQIQGVYPSKPAKTTGFGTAEPAAPCGNEGLFEVIKVGSNVSSLEAGDWVIPSHVNFGTWRTHALGNDDDFIKLPNPAQSKANGKPNGLTINQGATISVNPLTAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKLLNFNSISVIRDRPNLDEVVASLKELGATQVITEDQNNSKEFGPTIKEWIKQSGGEAKLALNCVGGKSSTGIARKLNNNGLMLTYGGMSFQPVTIPTSLYIFKNFTSAGFWVTELLKNNKELKTSTLNQIIAWYEEGKLTDAKSIETLYDGTKPLHELYQDGVANSKDGKQLITY</sequence>
        <attributeList>
          <attribute name="crc64">91ABE00831F0C2E8</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>etr1_cantr</shortLabel>
          <fullName>Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">2-enoyl thioester reductase 1</alias>
          <alias type="gene name" typeAc="MI:0301">ETR1</alias>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1GUF"/>
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        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
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          <xref>
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          </xref>
        </interactorType>
        <organism ncbiTaxId="5482">
          <names>
            <shortLabel>cantr</shortLabel>
            <fullName>Candida tropicalis (Yeast)</fullName>
          </names>
        </organism>
        <sequence>MYSVLKQSIRPRLLATHNQFRTMITAQAVLYTQHGEPKDVLFTQSFEIDDDNLAPNEVIVKTLGSPVNPSDINQIQGVYPSKPAKTTGFGTTEPAAPCGNEGLFEVIKVGSNVSSLEAGDWVIPSHVNFGTWRTHALGNDDDFIKLPNPAQSKANGKPNGLTINQGATISVNPLTAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKLLNFNSISVIRDRPNLDEVVASLKELGATQVITEDQNNSREFGPTIKEWIKQSGGEAKLALNCVGGKSSTGIARKLNNNGLMLTYGGMSFQPVTIPTSLYIFKNFTSAGFWVTELLKNNKELKTSTLNQIIAWYEEGKLTDAKSIETLYDGTKPLHELYQDGVANSKDGKQLITY</sequence>
        <attributeList>
          <attribute name="crc64">FCBC174A240742D8</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4">
        <names>
          <shortLabel>etr1-etr2-1</shortLabel>
        </names>
        <xref>
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          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1036936" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
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            </biologicalRole>
            <experimentalRoleList>
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                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
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            </experimentalRoleList>
            <featureList>
              <feature id="6">
                <names>
                  <shortLabel>region</shortLabel>
                </names>
                <xref>
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                <featureType>
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                    <fullName>sufficient binding region</fullName>
                    <alias type="synonym" typeAc="MI:1041">sufficient to bind</alias>
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                    </startStatus>
                    <begin position="1"/>
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                      <names>
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                    </endStatus>
                    <end position="386"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="4932">
                <names>
                  <shortLabel>yeasx</shortLabel>
                  <fullName>Saccharomyces cerevisiae (Baker's yeast)</fullName>
                  <alias type="synonym" typeAc="MI:1041">Baker's yeast</alias>
                </names>
              </hostOrganism>
            </hostOrganismList>
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                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
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                    </endStatus>
                    <end position="386"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="4932">
                <names>
                  <shortLabel>yeasx</shortLabel>
                  <fullName>Saccharomyces cerevisiae (Baker's yeast)</fullName>
                  <alias type="synonym" typeAc="MI:1041">Baker's yeast</alias>
                </names>
              </hostOrganism>
            </hostOrganismList>
            <stoichiometry value="3"/>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
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        <attributeList>
          <attribute name="assembly">dimeric, multimeric</attribute>
          <attribute name="3d-resolution" nameAc="MI:0632">1.98A</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>