IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ An NF-κB p65-cIAP2 link is necessary for mediating resistance to TNF-α induced cell death in gliomas. An NF-κB p65-cIAP2 link is necessary for mediating resistance to TNF-α induced cell death in gliomas. J. Neurooncol. (0167-594X) 2011 imex curation Zhao X., Laver T., Hong S.W., Twitty G.B., Devos A., Devos M., Benveniste E.N., Nozell S.E. IBD - Inflammatory bowel disease snozell@uab.edu 05-Jan-2015: Contacted by IntAct-Help. Only protein-protein interactions human-u251 Homo sapiens u251 U2521 glioblastoma cell line ch-ip chromatin immunoprecipitation assay ch-ip primer specific pcr primer specific pcr Zhao X., Laver T., Hong S.W., Twitty G.B., Devos A., Devos M., Benveniste E.N., Nozell S.E. IBD - Inflammatory bowel disease snozell@uab.edu Accepted 2014-DEC-02 by ORCHARD J. Neurooncol. (0167-594X) 2011 Only protein-protein interactions imex curation tf65_human Transcription factor p65 Nuclear factor NF-kappa-B p65 subunit RELA NFKB3 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 protein protein human Homo sapiens Human MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFSALLSQISS DIP protein Q04206 original sequence version: 170 DIP protein Q04206 original sequence version: 173 DIP protein Q04206 original sequence version: 99 DIP protein Q04206-1 original sequence version: 99 DIP protein Q04206 original sequence version: 168 DIP protein Q04206 original sequence version: 128 DIP protein Q04206 original sequence version: 131 DIP protein Q04206 original sequence version: 153 DIP protein Q04206 original sequence version: 185 DIP protein Q04206 original sequence version: 181 DIP protein Q04206 original sequence version: 183 8147A6AF9F2445C6 birc3_human_gene Human BIRC3 gene gene gene human Homo sapiens Human rela-birc3-1 1 3 unspecified role unspecified role prey prey promoter region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 2 unspecified role unspecified role bait bait association association Fig. 3c P01375 (Tumor necrosis factor alpha (TNF-alpha)) No cIAP-2 promoter DNA co-precipitated with anti-p65 antibody from cells not treated with TNF-alpha. Q04206 increases expression at RNA level of ENSG00000023445 Q04206 increases expression at protein level of ENSG00000023445 P01375 increases binding of Q04206 to ENSG00000023445 P01375 indirectly increases expression at RNA level of ENSG00000023445 P01375 indirectly increases expression at protein level of ENSG00000023445