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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>bhf-ucl</shortLabel>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1332" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6693962" refType="identity" refTypeAc="MI:0356"/>
      </xref>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>HEB and E2A function as SMAD/FOXH1 cofactors.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="21828274" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9542632" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-22642" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">HEB and E2A function as SMAD/FOXH1 cofactors.</attribute>
            <attribute name="journal" nameAc="MI:0885">Genes Dev. (0890-9369)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2011</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Yoon S.J., Wills A.E., Chuong E., Gupta R., Baker J.C.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Cardiac - Interactions involving cardiac related proteins</attribute>
            <attribute name="contact-email" nameAc="MI:0634">jbaker@stanford.edu</attribute>
            <attribute name="author-announcement">21-Jul-2014: Contacted by IntAct-Help.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="21828274" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22642" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human-endoerm</shortLabel>
              <fullName>Human endoderm</fullName>
            </names>
            <tissue>
              <names>
                <shortLabel>endoderm</shortLabel>
                <fullName>endoderm</fullName>
              </names>
              <xref>
                <primaryRef db="intact" dbAc="MI:0469" id="IA:2827" refType="identity" refTypeAc="MI:0356"/>
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              </xref>
            </tissue>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti bait coip</shortLabel>
            <fullName>anti bait coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti bait coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Yoon S.J., Wills A.E., Chuong E., Gupta R., Baker J.C.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Cardiac - Interactions involving cardiac related proteins</attribute>
          <attribute name="remark-internal">Note there is no information about whether the antibodies are monoclonal or polyclonal, even in Supplemental files</attribute>
          <attribute name="contact-email" nameAc="MI:0634">jbaker@stanford.edu</attribute>
          <attribute name="accepted">Accepted 2014-JUN-06 by ORCHARD</attribute>
          <attribute name="journal" nameAc="MI:0885">Genes Dev. (0890-9369)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2011</attribute>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
      <experimentDescription id="2">
        <names>
          <fullName>HEB and E2A function as SMAD/FOXH1 cofactors.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="21828274" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9542632" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-22642" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">HEB and E2A function as SMAD/FOXH1 cofactors.</attribute>
            <attribute name="journal" nameAc="MI:0885">Genes Dev. (0890-9369)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2011</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Yoon S.J., Wills A.E., Chuong E., Gupta R., Baker J.C.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Cardiac - Interactions involving cardiac related proteins</attribute>
            <attribute name="contact-email" nameAc="MI:0634">jbaker@stanford.edu</attribute>
            <attribute name="author-announcement">21-Jul-2014: Contacted by IntAct-Help.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-22642" refType="imex-primary" refTypeAc="MI:0662"/>
          <secondaryRef db="pubmed" dbAc="MI:0446" id="21828274" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human-embryonic_stem_ cells</shortLabel>
              <fullName>Human-embryonic_stem_ cells (es cells)</fullName>
            </names>
            <tissue>
              <names>
                <shortLabel>embryonic_stem_cell</shortLabel>
                <fullName>Embryonic stem cell (es cells)</fullName>
              </names>
              <xref>
                <primaryRef db="brenda" dbAc="MI:0864" id="BTO:0001086" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-6544292" refType="identity" refTypeAc="MI:0356"/>
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              </xref>
            </tissue>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti bait coip</shortLabel>
            <fullName>anti bait coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti bait coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Yoon S.J., Wills A.E., Chuong E., Gupta R., Baker J.C.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Cardiac - Interactions involving cardiac related proteins</attribute>
          <attribute name="remark-internal">Note there is no information about whether the antibodies are monoclonal or polyclonal, even in Supplemental files</attribute>
          <attribute name="contact-email" nameAc="MI:0634">jbaker@stanford.edu</attribute>
          <attribute name="accepted">Accepted 2014-JUN-06 by ORCHARD</attribute>
          <attribute name="journal" nameAc="MI:0885">Genes Dev. (0890-9369)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2011</attribute>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="3">
        <names>
          <shortLabel>tfe2_human</shortLabel>
          <fullName>Transcription factor E2-alpha</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Immunoglobulin enhancer-binding factor E12/E47</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Transcription factor 3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Immunoglobulin transcription factor 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Transcription factor ITF-1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Kappa-E2-binding factor</alias>
          <alias type="gene name" typeAc="MI:0301">TCF3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">E2A</alias>
          <alias type="gene name synonym" typeAc="MI:0302">ITF1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">BHLHB21</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Class B basic helix-loop-helix protein 21</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P15923" version="SP_104" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q2TB40" version="SP_109" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P15883" version="SP_104" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14208" version="SP_104" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14635" version="SP_104" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14636" version="SP_104" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UPI9" version="SP_104" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q2TB39" version="SP_178" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-11119608" refType="intact-secondary"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000262965" version="SP_237" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-769630" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001129611.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003191.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016882669.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016882670.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016882671.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-74N"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000791" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000987" version="SP_237"/>
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          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000262965" version="SP_237" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001227" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002326" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005667" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006355" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007399" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008134" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030183" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030890" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031435" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033152" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2YPA" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2YPB" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3U5V" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6MGN" version="SP_237"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-525793" version="SP_237"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8939236" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2MH0" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043425" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045666" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045787" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051091" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061629" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070644" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070888" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090575" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0140297" version="SP_237"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000045" version="SP_237"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011598" version="SP_237"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036638" version="SP_237"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1HLH" version="SP_237"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P15923 original sequence version: 171</attribute>
          <attribute name="remark-internal">DIP protein P15923 original sequence version: 132</attribute>
          <attribute name="remark-internal">DIP protein P15923 original sequence version: 126</attribute>
          <attribute name="crc64">52F5E3DE1890AE13</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>foxh1_human</shortLabel>
          <fullName>Forkhead box protein H1</fullName>
          <alias type="gene name" typeAc="MI:0301">FOXH1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">FAST1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">FAST2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Forkhead activin signal transducer 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Forkhead activin signal transducer 2</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="O75593" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DWM4" version="SP_90" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000366534" version="SP_184" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1759806" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003914.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000160973" version="SP_184" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000377317" version="SP_184" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" version="SP_184"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000987" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001947" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003139" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003151" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003215" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003222" version="SP_184"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005667" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007179" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032444" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033147" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035054" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035909" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043425" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043433" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046332" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048318" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050681" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060766" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070410" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070412" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071345" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1900164" version="SP_184"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001766" version="SP_184"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR030456" version="SP_184"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036388" version="SP_184"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036390" version="SP_184"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5XOC" version="SP_184"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1181150" version="SP_184"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1502540" version="SP_184"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MGPCSGSRLGPPEAESPSQPPKRRKKRYLRHDKPPYTYLAMIALVIQAAPSRRLKLAQIIRQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKVPKDPAKPQAKGNFWAVDVSLIPAEALRLQNTALCRRWQNGGARGAFAKDLGPYVLHGRPYRPPSPPPPPSEGFSIKSLLGGSGEGAPWPGLAPQSSPVPAGTGNSGEEAVPTPPLPSSERPLWPLCPLPGPTRVEGETVQGGAIGPSTLSPEPRAWPLHLLQGTAVPGGRSSGGHRASLWGQLPTSYLPIYTPNVVMPLAPPPTSCPQCPSTSPAYWGVAPETRGPPGLLCDLDALFQGVPPNKSIYDVWVSHPRDLAAPGPGWLLSWCSL</sequence>
        <attributeList>
          <attribute name="crc64">27A13F39C089F722</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>smad3_human</shortLabel>
          <fullName>Mothers against decapentaplegic homolog 3</fullName>
          <alias type="gene name" typeAc="MI:0301">SMAD3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">MADH3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SMAD family member 3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">JV15-2</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P84022" version="SP_50" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1760241" refType="intact-secondary"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O09064" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O09144" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O14510" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O35273" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q92940" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q93002" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9GKR4" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1965323" refType="intact-secondary"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K4B6" version="SP_76" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B7Z9Q2" version="SP_108" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B7Z4Z5" version="SP_106" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B7Z6M9" version="SP_115" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="F5H383" version="SP_115" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000332973" version="SP_196" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-347161" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001138574.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001138575.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_005893.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001138576.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29720N"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000166949" version="SP_196" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000327367" version="SP_196" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000987" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001217" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001223" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001657" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001701" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001707" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001756" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001889" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001947" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002076" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002520" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005160" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005518" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005637" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005667" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006919" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006955" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007179" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007183" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007492" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008013" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008134" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008270" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009653" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009880" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010694" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010718" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016202" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0017015" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0017151" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019902" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0023019" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030154" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030308" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030325" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030335" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030501" version="SP_196"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032924" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033689" version="SP_196"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0038092" version="SP_196"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043130" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043235" version="SP_196"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045216" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045429" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045599" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045668" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045930" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048340" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048589" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048617" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048701" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050678" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050728" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050776" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050821" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050927" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051091" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051098" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051481" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051496" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051726" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051894" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060039" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060290" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060395" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061045" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061629" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061767" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070306" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070410" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070411" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070412" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071141" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071144" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071560" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090263" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097191" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097296" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901203" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1902895" version="SP_196"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1903243" version="SP_196"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001132" version="SP_196"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003619" version="SP_196"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008984" version="SP_196"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013019" version="SP_196"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013790" version="SP_196"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017855" version="SP_196"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036578" version="SP_196"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P84022" version="SP_196"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MHD" version="SP_196"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MJS" version="SP_196"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MK2" version="SP_196"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OZJ" version="SP_196"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1U7F" version="SP_196"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LAJ" version="SP_196"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LB2" version="SP_196"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OD6" version="SP_196"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5ODG" version="SP_196"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5XOC" version="SP_196"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ZMN" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1181150" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1502540" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173788" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173789" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173795" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173796" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3304356" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3311021" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3315487" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3656532" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5689880" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8941855" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8952158" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9008059" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013695" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9615017" version="SP_196"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9617828" version="SP_196"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P84022 original sequence version: 57</attribute>
          <attribute name="remark-internal">DIP protein P84022 original sequence version: 112</attribute>
          <attribute name="remark-internal">DIP protein P84022-1 original sequence version: 146</attribute>
          <attribute name="remark-internal">DIP protein P84022-1 original sequence version: 111</attribute>
          <attribute name="crc64">46DF5E8B371321AC</attribute>
        </attributeList>
      </interactor>
      <interactor id="6">
        <names>
          <shortLabel>htf4_human</shortLabel>
          <fullName>Transcription factor 12</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Transcription factor HTF-4</alias>
          <alias type="gene name synonym" typeAc="MI:0302">E-box-binding protein</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DNA-binding protein HTF4</alias>
          <alias type="gene name" typeAc="MI:0301">TCF12</alias>
          <alias type="gene name synonym" typeAc="MI:0302">HEB</alias>
          <alias type="gene name synonym" typeAc="MI:0302">HTF4</alias>
          <alias type="gene name synonym" typeAc="MI:0302">BHLHB20</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Class B basic helix-loop-helix protein 20</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q99081" version="SP_67" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q86VM2" version="SP_95" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000267811" version="SP_195" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000453737" version="SP_195" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q7Z3D9" version="SP_91" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q86TC1" version="SP_91" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4E1W1" version="SP_138" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-722877" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001309086.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003196.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_996919.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_996920.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_996921.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_996923.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000140262" version="SP_195" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000267811" version="SP_195" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000557843" version="SP_195" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000987" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005667" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006955" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007399" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007517" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008134" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016607" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030154" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035497" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043231" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043425" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045666" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046332" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070888" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071837" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090575" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990837" version="SP_195"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011598" version="SP_195"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036638" version="SP_195"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001309080.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001293149.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001309088.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001309091.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001309094.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29403N"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q99081" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2KNH" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JOL" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-525793" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8939236" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9031628" version="SP_195"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q99081 original sequence version: 135</attribute>
          <attribute name="remark-internal">DIP protein Q99081 original sequence version: 56</attribute>
          <attribute name="remark-internal">DIP protein Q99081 original sequence version: 91</attribute>
          <attribute name="remark-internal">DIP protein Q99081 original sequence version: 85</attribute>
          <attribute name="crc64">9736113D9361D3F5</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="7" imexId="IM-22642-1">
        <names>
          <shortLabel>smad3-foxh1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9542651" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22642-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="8">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="9">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Fig 2C</attribute>
        </attributeList>
      </interaction>
      <interaction id="10" imexId="IM-22642-2">
        <names>
          <shortLabel>smad3-tcf3</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9542655" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22642-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="11">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="12">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Fig 2C</attribute>
        </attributeList>
      </interaction>
      <interaction id="13" imexId="IM-22642-3">
        <names>
          <shortLabel>tcf3-foxh1-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9542660" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22642-3" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="14">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">HEB</alias>
            </names>
            <interactorRef>6</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="15">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Fig 2C</attribute>
        </attributeList>
      </interaction>
      <interaction id="16" imexId="IM-22642-4">
        <names>
          <shortLabel>smad3-tcf12</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9542666" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22642-4" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="17">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">HEB</alias>
            </names>
            <interactorRef>6</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="18">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Fig 2C</attribute>
        </attributeList>
      </interaction>
      <interaction id="19" imexId="IM-22642-5">
        <names>
          <shortLabel>foxh1-smad3</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9542673" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22642-5" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="20">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">HEB</alias>
            </names>
            <interactorRef>6</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="21">
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>cell lysate</shortLabel>
                  <fullName>cell lysate</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0344" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537757" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Fig 2C</attribute>
        </attributeList>
      </interaction>
      <interaction id="22" imexId="IM-22642-6">
        <names>
          <shortLabel>smad3-tcf3-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9542695" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22642-6" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="23">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="24">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Fig 2C</attribute>
        </attributeList>
      </interaction>
      <interaction id="25" imexId="IM-22642-7">
        <names>
          <shortLabel>tcf12-foxh1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9542697" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22642-7" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="26">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">HEB</alias>
            </names>
            <interactorRef>6</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="27">
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>cell lysate</shortLabel>
                  <fullName>cell lysate</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0344" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537757" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Fig 2C</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>