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        <names>
          <fullName>Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5.</fullName>
        </names>
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            <attribute name="publication title" nameAc="MI:1091">Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5.</attribute>
            <attribute name="journal" nameAc="MI:0885">Biochem. Biophys. Res. Commun. (0006-291X)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2004</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Fruchart-Najib J., Baugé E., Niculescu L.S., Pham T., Thomas B., Rommens C., Majd Z., Brewer B., Pennacchio L.A., Fruchart J.C.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Cardiac - Interactions involving cardiac related proteins</attribute>
            <attribute name="data-processing" nameAc="MI:0633">Interaction of ApoAV and recombinant LPL in Fig. 4 was not annotated because the authors don't provide the information of the origin organism of the recombinant LPL</attribute>
            <attribute name="contact-email" nameAc="MI:0634">jamila.fruchart@pasteur-lille.fr</attribute>
            <attribute name="author-announcement">20-Oct-2014: Contacted by IntAct-Help.</attribute>
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          <attribute name="accepted">Accepted 2014-SEP-18 by PPORRAS</attribute>
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            <fullName>Homo sapiens</fullName>
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        <sequence>MESKALLVLTLAVWLQSLTASRGGVAAADQRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLNKKSG</sequence>
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          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHDQGHSHLGDP</sequence>
        <attributeList>
          <attribute name="crc64">A1C9C207024D0DAF</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>lipl_bovin</shortLabel>
          <fullName>Lipoprotein lipase</fullName>
          <alias type="gene name" typeAc="MI:0301">LPL</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Phospholipase A1</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P11151" version="SP_113" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSBTAP00000017086" version="SP_170" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q17R03" version="SP_113" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8794090" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006633" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006641" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006644" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008201" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008970" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009749" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010886" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010890" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016042" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016298" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019433" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032722" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034185" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034361" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034371" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034372" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042627" version="SP_170"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSBTAG00000012855" version="SP_170" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSBTAT00000017086" version="SP_170" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004465" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004620" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004806" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_170"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001068588.1"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001024" version="SP_170"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002330" version="SP_170"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013818" version="SP_170"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016272" version="SP_170"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029058" version="SP_170"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033906" version="SP_170"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036392" version="SP_170"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6U7M" version="SP_170"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-BTA-8963889" version="SP_170"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000734" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042632" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043395" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045600" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0052739" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0052740" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0055096" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070328" version="SP_170"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071813" version="SP_170"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-61310N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9913">
          <names>
            <shortLabel>bovin</shortLabel>
            <fullName>Bos taurus (Bovine)</fullName>
            <alias type="synonym" typeAc="MI:1041">Bovine</alias>
          </names>
        </organism>
        <sequence>MESKALLLLALSVCLQSLTVSRGGLVAADRITGGKDFRDIESKFALRTPEDTAEDTCHLIPGVTESVANCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQQHYPVSAGYTKLVGQDVAKFMNWMADEFNYPLGNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEALRVIAERGLGDVDQLVKCSHERSVHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNMGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESNTYTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLLYTEVDIGELLMLKLKWISDSYFSWSNWWSSPGFDIGKIRVKAGETQKKVIFCSREKMSYLQKGKSPVIFVKCHDKSLNRKSG</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P11151 original sequence version: 125</attribute>
          <attribute name="crc64">06FDD429DD194A1F</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="5" imexId="IM-23099-1">
        <names>
          <shortLabel>apoa5-lpl-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9256330" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-23099-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="6">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="7">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Fig. 4</attribute>
        </attributeList>
      </interaction>
      <interaction id="8" imexId="IM-23099-2">
        <names>
          <shortLabel>apoa5-lpl-2</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9980672" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-23099-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="9">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="10">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Fig.4</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>