IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia. Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia. Cancer Cell (1535-6108) 2013 imex curation Khandanpour C., Phelan J.D., Vassen L., Schütte J., Chen R., Horman S.R., Gaudreau M.C., Krongold J., Zhu J., Paul W.E., Dührsen U., Göttgens B., Grimes H.L., Möröy T. Cancer - Interactions investigated in the context of cancer The authors state that the Gfi1-Flag contruct used in Fig 5H contains the human GFI1 sequence. Tarik.Moroy@ircm.qc.ca,Lee.Grimes@cchmc.org 27-Mar-2013: Contacted by IntAct-Help. Only protein-protein interactions mouse-hematopoietic progenitors MOUSE bone marrow hematopoietic progenitor cells hematopoietic progenitor cells Bone marrow hematopoietic progenitor cells/HSC-haematopoietic stem cells ch-ip chromatin immunoprecipitation assay ch-ip nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Khandanpour C., Phelan J.D., Vassen L., Schütte J., Chen R., Horman S.R., Gaudreau M.C., Krongold J., Zhu J., Paul W.E., Dührsen U., Göttgens B., Grimes H.L., Möröy T. Cancer - Interactions investigated in the context of cancer Cells immortalized by retroviral transduction of an MLL-ENL expression vector. Sequencing was carried out using an Illumina Genome Analyzer. The authors state that the Gfi1-Flag contruct used in Fig 5H contains the human GFI1 sequence. lee.grimes@cchmc.org,tarik.moroy@ircm.qc.ca Tarik.Moroy@ircm.qc.ca,Lee.Grimes@cchmc.org Accepted 2013-MAR-05 by ORCHARD 27-Mar-2013: Contacted by IntAct-Help. Cancer Cell (1535-6108) 2013 Only protein-protein interactions imex curation Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia. Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia. Cancer Cell (1535-6108) 2013 imex curation Khandanpour C., Phelan J.D., Vassen L., Schütte J., Chen R., Horman S.R., Gaudreau M.C., Krongold J., Zhu J., Paul W.E., Dührsen U., Göttgens B., Grimes H.L., Möröy T. Cancer - Interactions investigated in the context of cancer The authors state that the Gfi1-Flag contruct used in Fig 5H contains the human GFI1 sequence. Tarik.Moroy@ircm.qc.ca,Lee.Grimes@cchmc.org 27-Mar-2013: Contacted by IntAct-Help. Only protein-protein interactions human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Khandanpour C., Phelan J.D., Vassen L., Schütte J., Chen R., Horman S.R., Gaudreau M.C., Krongold J., Zhu J., Paul W.E., Dührsen U., Göttgens B., Grimes H.L., Möröy T. Cancer - Interactions investigated in the context of cancer The authors state that the Gfi1-Flag contruct used in Fig 5H contains the human GFI1 sequence. lee.grimes@cchmc.org,tarik.moroy@ircm.qc.ca Tarik.Moroy@ircm.qc.ca,Lee.Grimes@cchmc.org Accepted 2013-MAR-05 by ORCHARD 27-Mar-2013: Contacted by IntAct-Help. Cancer Cell (1535-6108) 2013 Only protein-protein interactions imex curation Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia. Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia. Cancer Cell (1535-6108) 2013 imex curation Khandanpour C., Phelan J.D., Vassen L., Schütte J., Chen R., Horman S.R., Gaudreau M.C., Krongold J., Zhu J., Paul W.E., Dührsen U., Göttgens B., Grimes H.L., Möröy T. Cancer - Interactions investigated in the context of cancer The authors state that the Gfi1-Flag contruct used in Fig 5H contains the human GFI1 sequence. Tarik.Moroy@ircm.qc.ca,Lee.Grimes@cchmc.org 27-Mar-2013: Contacted by IntAct-Help. Only protein-protein interactions mouse-thymocyte MOUSE THYMOCYTE thymocyte THYMOCYTE ch-ip chromatin immunoprecipitation assay ch-ip q-pcr quantitative pcr q-pcr Khandanpour C., Phelan J.D., Vassen L., Schütte J., Chen R., Horman S.R., Gaudreau M.C., Krongold J., Zhu J., Paul W.E., Dührsen U., Göttgens B., Grimes H.L., Möröy T. Cancer - Interactions investigated in the context of cancer For the genes - I have entered promoter regions where this is clearly correct. No features have been entered if I could not get any results from blatting, or if the primers were located within the body of the gene somewhere. I have entered all genes except Snai2 from S4K, and have not entered Jun, ccdc45,pten,fam53b, spice 1 nor Snai2 from S4 L. (so this = 8 genes from S4 L - rather than the 9 the text suggests...maybe the JUN error bar hides a star?!) Thymocytes were irradiated (5 Gy) and chromatin was generated either at 90 minutes later (Fig S4 K/L) or at 0, 30, 60, 90 and 120 minutes later (Fig S4 M). The authors state that the Gfi1-Flag contruct used in Fig 5H contains the human GFI1 sequence. lee.grimes@cchmc.org,tarik.moroy@ircm.qc.ca Tarik.Moroy@ircm.qc.ca,Lee.Grimes@cchmc.org Accepted 2013-MAR-05 by ORCHARD 27-Mar-2013: Contacted by IntAct-Help. Cancer Cell (1535-6108) 2013 Only protein-protein interactions imex curation Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia. Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia. Cancer Cell (1535-6108) 2013 imex curation Khandanpour C., Phelan J.D., Vassen L., Schütte J., Chen R., Horman S.R., Gaudreau M.C., Krongold J., Zhu J., Paul W.E., Dührsen U., Göttgens B., Grimes H.L., Möröy T. Cancer - Interactions investigated in the context of cancer The authors state that the Gfi1-Flag contruct used in Fig 5H contains the human GFI1 sequence. Tarik.Moroy@ircm.qc.ca,Lee.Grimes@cchmc.org 27-Mar-2013: Contacted by IntAct-Help. Only protein-protein interactions mouse-thymocyte MOUSE THYMOCYTE thymocyte THYMOCYTE anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Khandanpour C., Phelan J.D., Vassen L., Schütte J., Chen R., Horman S.R., Gaudreau M.C., Krongold J., Zhu J., Paul W.E., Dührsen U., Göttgens B., Grimes H.L., Möröy T. Cancer - Interactions investigated in the context of cancer I have left in the opser feature (S15) as the same antibody was used as for human expt. However, nothing is stated about this in the paper and the equivalent murine site to S15 is not stated -probably be the same serine according to UniProt....(could be added as ?-?) No details about the antibody (e.g.supplier/source) are given. 10Gy gamma- irradiation The authors state that the Gfi1-Flag contruct used in Fig 5H contains the human GFI1 sequence. lee.grimes@cchmc.org,tarik.moroy@ircm.qc.ca Tarik.Moroy@ircm.qc.ca,Lee.Grimes@cchmc.org Accepted 2013-MAR-05 by ORCHARD 27-Mar-2013: Contacted by IntAct-Help. Cancer Cell (1535-6108) 2013 Only protein-protein interactions imex curation Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia. Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia. Cancer Cell (1535-6108) 2013 imex curation Khandanpour C., Phelan J.D., Vassen L., Schütte J., Chen R., Horman S.R., Gaudreau M.C., Krongold J., Zhu J., Paul W.E., Dührsen U., Göttgens B., Grimes H.L., Möröy T. Cancer - Interactions investigated in the context of cancer The authors state that the Gfi1-Flag contruct used in Fig 5H contains the human GFI1 sequence. Tarik.Moroy@ircm.qc.ca,Lee.Grimes@cchmc.org 27-Mar-2013: Contacted by IntAct-Help. Only protein-protein interactions mouse-thymocyte MOUSE THYMOCYTE thymocyte THYMOCYTE ch-ip chromatin immunoprecipitation assay ch-ip primer specific pcr primer specific pcr Khandanpour C., Phelan J.D., Vassen L., Schütte J., Chen R., Horman S.R., Gaudreau M.C., Krongold J., Zhu J., Paul W.E., Dührsen U., Göttgens B., Grimes H.L., Möröy T. Cancer - Interactions investigated in the context of cancer Primers were from Gfi1-bound regions. Assays were carried out before and after irradiation. The authors state that the Gfi1-Flag contruct used in Fig 5H contains the human GFI1 sequence. lee.grimes@cchmc.org,tarik.moroy@ircm.qc.ca Tarik.Moroy@ircm.qc.ca,Lee.Grimes@cchmc.org Accepted 2013-MAR-05 by ORCHARD 27-Mar-2013: Contacted by IntAct-Help. Cancer Cell (1535-6108) 2013 Only protein-protein interactions imex curation apr_mouse_gene Pmaip1 /Noxa gene Mouse Gene gene gene mouse Mus musculus Mouse p53_human Cellular tumor antigen p53 TP53 P53 Tumor suppressor p53 Phosphoprotein p53 Antigen NY-CO-13 protein protein human Homo sapiens Human MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD DIP protein P04637 original sequence version: 121 DIP protein P04637 original sequence version: 115 DIP protein P04637-1 original sequence version: 224 DIP protein P04637 original sequence version: 117 DIP protein P04637-1 original sequence version: 226 DIP protein P04637 original sequence version: 226 DIP protein P04637 original sequence version: 212 DIP protein P04637 original sequence version: 220 DIP protein P04637-1 original sequence version: 220 DIP protein P04637-1 original sequence version: 145 DIP protein P04637 original sequence version: 146 DIP protein P04637 original sequence version: 145 DIP protein P04637 original sequence version: 166 DIP protein P04637-1 original sequence version: 166 DIP protein P04637 original sequence version: 169 DIP protein P04637 original sequence version: 177 DIP protein P04637 original sequence version: 175 DIP protein P04637-1 original sequence version: 175 DIP protein P04637-1 original sequence version: 172 DIP protein P04637-1 original sequence version: 169 DIP protein P04637 original sequence version: 170 DIP protein P04637 original sequence version: 172 DIP protein P04637-1 original sequence version: 194 DIP protein P04637 original sequence version: 196 DIP protein P04637 original sequence version: 185 DIP protein P04637-1 original sequence version: 191 DIP protein P04637 original sequence version: 191 DIP protein P04637 original sequence version: 180 DIP protein P04637-1 original sequence version: 197 DIP protein P04637 original sequence version: 183 DIP protein P04637-1 original sequence version: 183 DIP protein P04637-1 original sequence version: 185 DIP protein P04637 original sequence version: 199 DIP protein P04637 original sequence version: 201 DIP protein P04637 original sequence version: 189 DIP protein P04637 original sequence version: 235 DIP protein P04637 original sequence version: 230 DIP protein P04637 original sequence version: 234 DIP protein P04637-1 original sequence version: 234 DIP protein P04637-1 original sequence version: 235 DIP protein P04637 original sequence version: 239 DIP protein P04637-1 original sequence version: 212 DIP protein P04637-1 original sequence version: 213 DIP protein P04637 original sequence version: 213 DIP protein P04637 original sequence version: 206 DIP protein P04637-1 original sequence version: 188 DIP protein P04637-1 original sequence version: 228 DIP protein P04637 original sequence version: 208 DIP protein P04637 original sequence version: 240 DIP protein P04637-1 original sequence version: 240 DIP protein P04637 original sequence version: 204 DIP protein P04637-1 original sequence version: 204 DIP protein P04637-1 original sequence version: 209 DIP protein P04637-1 original sequence version: 203 DIP protein P04637 original sequence version: 221 DIP protein P04637-1 original sequence version: 152 DIP protein P04637 original sequence version: 217 DIP protein P04637-1 original sequence version: 140 DIP protein P04637 original sequence version: 215 DIP protein P04637 original sequence version: 214 DIP protein P04637-1 original sequence version: 182 DIP protein P04637 original sequence version: 182 DIP protein P04637 original sequence version: 188 DIP protein P04637 original sequence version: 192 DIP protein P04637-1 original sequence version: 192 DIP protein P04637 original sequence version: 218 DIP protein P04637-1 original sequence version: 218 AD5C149FD8106131 gfi1_mouse Zinc finger protein Gfi-1 Gfi1 Gfi-1 Growth factor independent protein 1 protein protein mouse Mus musculus Mouse MPRSFLVKSKKAHSYHQPRSPGPDYSLRLETVPAPGRAEGGAVSAGESKMEPRERLSPDSQLTEAPDRASASPNSCEGSVCDPCSEFEDFWRPPSPSVSPASEKSLCRSLDEAQPYTLPFKPYAWSGLAGSDLRHLVQSYRQCSALERSAGLSLFCERGSEPGRPAARYGPEQAAGGAGAGQPGRCGVAGGATSAAGLGLYGDFAPAAAGLYERPSTAAGRLYQDHGHELHADKSVGVKVESELLCTRLLLGGGSYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFACEMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRETQHGLK 63AB726025300B6B gfi1_human Zinc finger protein Gfi-1 Growth factor independent protein 1 Zinc finger protein 163 GFI1 ZNF163 protein protein human Homo sapiens Human MPRSFLVKSKKAHSYHQPRSPGPDYSLRLENVPAPSRADSTSNAGGAKAEPRDRLSPESQLTEAPDRASASPDSCEGSVCERSSEFEDFWRPPSPSASPASEKSMCPSLDEAQPFPLPFKPYSWSGLAGSDLRHLVQSYRPCGALERGAGLGLFCEPAPEPGHPAALYGPKRAAGGAGAGAPGSCSAGAGATAGPGLGLYGDFGSAAAGLYERPTAAAGLLYPERGHGLHADKGAGVKVESELLCTRLLLGGGSYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFACEMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRETQHGLK DIP protein Q99684 original sequence version: 93 DIP protein Q99684 original sequence version: 94 740A466F72C5FC72 p53_mouse Cellular tumor antigen p53 Tp53 P53 Trp53 Tumor suppressor p53 protein protein mouse Mus musculus Mouse MTAMEESQSDISLELPLSQETFSGLWKLLPPEDILPSPHCMDDLLLPQDVEEFFEGPSEALRVSGAPAAQDPVTETPGPVAPAPATPWPLSSFVPSQKTYQGNYGFHLGFLQSGTAKSVMCTYSPPLNKLFCQLAKTCPVQLWVSATPPAGSRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNLYPEYLEDRQTFRHSVVVPYEPPEAGSEYTTIHYKYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKKEVLCPELPPGSAKRALPTCTSASPPQKKKPLDGEYFTLKIRGRKRFEMFRELNEALELKDAHATEESGDSRAHSSYLKTKKGQSTSRHKKTMVKKVGPDSD DIP protein P02340 original sequence version: 117 DIP protein P02340 original sequence version: 165 DIP protein P02340 original sequence version: 187 DIP protein P02340 original sequence version: 201 DIP protein P02340 original sequence version: 111 DIP protein P02340 original sequence version: 141 DIP protein P02340 original sequence version: 180 DIP protein P02340 original sequence version: 163 DIP protein P02340 original sequence version: 152 ED5A607378D921D7 ddb2_mouse_gene DDB2_MOUSE GENE gene gene mouse Mus musculus Mouse vdr_mouse_gene VDR MOUSE GENE gene gene mouse Mus musculus Mouse cdn1a_mouse_gene CDN1A_MOUSE_GENE gene gene mouse Mus musculus Mouse bax_mouse_gene BAX MOUSE GENE gene gene mouse Mus musculus Mouse id2_mouse_gene Mouse Id2 gene gene gene mouse Mus musculus Mouse bbc3_mouse_gene BBC3_MOUSE_GENE gene gene mouse Mus musculus Mouse pten_mouse_gene PTEN_MOUSE_GENE gene gene mouse Mus musculus Mouse egr2_mouse_gene EGR2 MOUSE GENE gene gene mouse Mus musculus Mouse jun_mouse_gene JUN MOUSE GENE gene gene mouse Mus musculus Mouse cep95_mouse_gene CEP95_MOUSE_GENE/Ccdc45 gene gene mouse Mus musculus Mouse gfi1-tp53-1 2 7 unspecified role unspecified role prey prey possible_phospho-ser15 opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations certain certain sequence position certain certain certain sequence position certain 9 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association 5H gamma-ray irradiation (6Gy) increased levels of S15 phosphorylated- p53 detected. gfi1-tp53-2 4 8 unspecified role unspecified role bait bait 10 unspecified role unspecified role prey prey possible_phosph-ser15 opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations certain certain sequence position certain certain certain sequence position certain physical association physical association 5I gfi1-mouse 1 8 unspecified role unspecified role bait bait 14 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 5Dii gfi1-mouse-1 1 8 unspecified role unspecified role bait bait 6 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 5D gfi1-mouse-2 1 8 unspecified role unspecified role bait bait 16 unspecified role unspecified role prey prey association association 5Diii gfi1-mouse-5 5 14 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 unspecified role unspecified role bait bait association association 5Eii 6Gy gamma irradiation gfi1-mouse-5 5 10 unspecified role unspecified role bait bait 6 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 5E 6Gy gamma irradiation gfi1-bbc3-1 5 16 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 unspecified role unspecified role bait bait association association 5Eiii 6Gy gamma irradiation gfi1-mouse-6 3 10 unspecified role unspecified role bait bait 14 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association S4 L/M Co-occupation by Gfi1 and p53 is maintained over time, but p53 occupation clearly dominates at 120 min after the initial DNA damage signal over Gfi1. gfi1-mouse-6 3 10 unspecified role unspecified role bait bait 6 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association S4 L/M Co-occupation by Gfi1 and p53 is maintained over time, but p53 occupation clearly dominates at 120 min after the initial DNA damage signal over Gfi1. gfi1-bbc3-2 3 16 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait association association S4 L/M Co-occupation by Gfi1 and p53 is maintained over time, but p53 occupation clearly dominates at 120 min after the initial DNA damage signal over Gfi1. gfi1-mouse-7 3 8 unspecified role unspecified role bait bait 14 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association S4 K/M Co-occupation by Gfi1 and p53 is maintained over time, but p53 occupation clearly dominates at 120 min after the initial DNA damage signal over Gfi1. gfi1-mouse-8 3 8 unspecified role unspecified role bait bait 6 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association S4 K/M Co-occupation by Gfi1 and p53 is maintained over time, but p53 occupation clearly dominates at 120 min after the initial DNA damage signal over Gfi1. gfi1-bbc3-3 3 8 unspecified role unspecified role bait bait 16 unspecified role unspecified role prey prey association association S4 K/M Co-occupation by Gfi1 and p53 is maintained over time, but p53 occupation clearly dominates at 120 min after the initial DNA damage signal over Gfi1. gfi1-bbc3-4 3 8 unspecified role unspecified role bait bait 13 unspecified role unspecified role prey prey association association S4 K/M Co-occupation by Gfi1 and p53 is maintained over time, but p53 occupation clearly dominates at 120 min after the initial DNA damage signal over Gfi1. tp53-bbc3-6 3 13 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 unspecified role unspecified role bait bait association association S4 L/M Co-occupation by Gfi1 and p53 is maintained over time, but p53 occupation clearly dominates at 120 min after the initial DNA damage signal over Gfi1. gfi1-mouse-9 3 8 unspecified role unspecified role bait bait 20 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association S4 K gfi1-bbc3-5 3 8 unspecified role unspecified role bait bait 17 unspecified role unspecified role prey prey association association S4 K gfi1-bbc3-6 3 8 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey association association S4 K tp53-bbc3-8 3 11 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait association association S4 L gfi1-bbc3-7 3 8 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey association association S4 K tp53-bbc3-9 3 15 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait association association S4 L gfi1-bbc3-8 3 8 unspecified role unspecified role bait bait 18 unspecified role unspecified role prey prey association association S4 K tp53-ddb2 3 18 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait association association S4 L gfi1-bbc3-9 3 8 unspecified role unspecified role bait bait 19 unspecified role unspecified role prey prey association association S4 K gfi1-mouse-11 3 8 unspecified role unspecified role bait bait 12 unspecified role unspecified role prey prey promoter_region binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association S4 K