<?xml version='1.0' encoding='UTF-8'?>
<entrySet xmlns="http://psi.hupo.org/mi/mif300" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://psi.hupo.org/mi/mif300 https://raw.githubusercontent.com/HUPO-PSI/miXML/master/3.0/src/MIF300.xsd" level="3" version="0" minorVersion="0">
  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>Molecular Connections</shortLabel>
        <fullName>Molecular Connections Pvt. Ltd.</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1263" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2643791" refType="identity" refTypeAc="MI:0356"/>
      </xref>
      <attributeList>
        <attribute name="postal address">2/2, Kariappa Road, Basavanagudi, Bangalore -560 004</attribute>
        <attribute name="url" nameAc="MI:0614">www.molecularconnections.com</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Androgen up-regulates vascular endothelial growth factor expression in prostate cancer cells via an Sp1 binding site.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="23369005" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9074028" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-21843" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Androgen up-regulates vascular endothelial growth factor expression in prostate cancer cells via an Sp1 binding site.</attribute>
            <attribute name="journal" nameAc="MI:0885">Mol. Cancer</attribute>
            <attribute name="publication year" nameAc="MI:0886">2013</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Eisermann K., Broderick C.J., Bazarov A., Moazam M.M., Fraizer G.C.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Cancer - Interactions investigated in the context of cancer</attribute>
            <attribute name="contact-email" nameAc="MI:0634">gfraizer@kent.edu</attribute>
            <attribute name="author-announcement">13-Jan-2014: Contacted by IntAct-Help.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="external curation">Molecular Connections Pvt. Ltd.</attribute>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-21843" refType="imex-primary" refTypeAc="MI:0662"/>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human-22rv1</shortLabel>
              <fullName>Homo sapiens</fullName>
            </names>
            <cellType>
              <names>
                <shortLabel>22rv1</shortLabel>
                <fullName>Human prostate adenocarcinoma cell line</fullName>
              </names>
              <xref>
                <primaryRef db="intact" dbAc="MI:0469" id="IA:0165" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-4652066" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-782969" refType="identity" refTypeAc="MI:0356"/>
              </xref>
              <attributeList>
                <attribute name="comment" nameAc="MI:0612">Also known as CWR22Rv1 or Rv1. Cells dsplay a NE (neuroendocrine phenotype).</attribute>
              </attributeList>
            </cellType>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti bait coip</shortLabel>
            <fullName>anti bait coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti bait coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Eisermann K., Broderick C.J., Bazarov A., Moazam M.M., Fraizer G.C.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Cancer - Interactions investigated in the context of cancer</attribute>
          <attribute name="contact-email" nameAc="MI:0634">gfraizer@kent.edu</attribute>
          <attribute name="accepted">Accepted 2013-DEC-20 by PPORRAS</attribute>
          <attribute name="journal" nameAc="MI:0885">Mol. Cancer</attribute>
          <attribute name="publication year" nameAc="MI:0886">2013</attribute>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959"/>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
          <attribute name="external curation">Molecular Connections Pvt. Ltd.</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>sp1_human</shortLabel>
          <fullName>Transcription factor Sp1</fullName>
          <alias type="gene name" typeAc="MI:0301">SP1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">TSFP1</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P08047" version="SP_105" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q86TN8" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9H3Q5" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NR51" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NY21" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NYE7" version="SP_105" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-28977878" refType="intact-secondary"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000329357" version="SP_249" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E4Z9M7" version="SP_179" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="G5E9M8" version="SP_179" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-298336" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003100.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_612482.2"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000185591" version="SP_249" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000327443" version="SP_249" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000791" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000977" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000987" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001221" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003690" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006355" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008022" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008134" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0017053" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032869" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032993" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033194" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035035" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042826" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043425" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043536" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043923" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045766" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048511" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061629" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071837" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0140297" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1902004" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1904828" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1905564" version="SP_249"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990837" version="SP_249"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013087" version="SP_249"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036236" version="SP_249"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P08047" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1SP1" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1SP2" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1VA1" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1VA2" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1VA3" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PV0" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PV1" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PV2" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PV3" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UCO" version="SP_249"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UCP" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1989781" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173796" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2426168" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2559585" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6807505" version="SP_249"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9018519" version="SP_249"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000329357"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000426431"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000404263"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001238754.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011536998.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-36N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MSDQDHSMDEMTAVVKIEKGVGGNNGGNGNGGGAFSQARSSSTGSSSSTGGGGQESQPSPLALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQLSQGANGWQIISSSSGATPTSKEQSGSSTNGSNGSESSKNRTVSGGQYVVAAAPNLQNQQVLTGLPGVMPNIQYQVIPQFQTVDGQQLQFAATGAQVQQDGSGQIQIIPGANQQIITNRGSGGNIIAAMPNLLQQAVPLQGLANNVLSGQTQYVTNVPVALNGNITLLPVNSVSAATLTPSSQAVTISSSGSQESGSQPVTSGTTISSASLVSSQASSSSFFTNANSYSTTTTTSNMGIMNFTTSGSSGTNSQGQTPQRVSGLQGSDALNIQQNQTSGGSLQAGQQKEGEQNQQTQQQQILIQPQLVQGGQALQALQAAPLSGQTFTTQAISQETLQNLQLQAVPNSGPIIIRTPTVGPNGQVSWQTLQLQNLQVQNPQAQTITLAPMQGVSLGQTSSSNTTLTPIASAASIPAGTVTVNAAQLSSMPGLQTINLSALGTSGIQVHPIQGLPLAIANAPGDHGAQLGLHGAGGDGIHDDTAGGEEGENSPDAQPQAGRRTRREACTCPYCKDSEGRGSGDPGKKKQHICHIQGCGKVYGKTSHLRAHLRWHTGERPFMCTWSYCGKRFTRSDELQRHKRTHTGEKKFACPECPKRFMRSDHLSKHIKTHQNKKGGPGVALSVGTLPLDSGAGSEGSGTATPSALITTNMVAMEAICPEGIARLANSGINVMQVADLQSINISGNGF</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P08047 original sequence version: 185</attribute>
          <attribute name="remark-internal">DIP protein P08047 original sequence version: 187</attribute>
          <attribute name="remark-internal">DIP protein P08047 original sequence version: 181</attribute>
          <attribute name="remark-internal">DIP protein P08047 original sequence version: 162</attribute>
          <attribute name="remark-internal">DIP protein P08047 original sequence version: 161</attribute>
          <attribute name="crc64">43893DBF6518B9EA</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>andr_human</shortLabel>
          <fullName>Androgen receptor</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Dihydrotestosterone receptor</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Nuclear receptor subfamily 3 group C member 4</alias>
          <alias type="gene name" typeAc="MI:0301">AR</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DHTR</alias>
          <alias type="gene name synonym" typeAc="MI:0302">NR3C4</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P10275" version="SP_142" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000363822" version="SP_288" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000484033" version="SP_288" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A2RUN2" version="SP_146" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B1AKD7" version="SP_156" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UD95" version="SP_164" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-11476138" refType="intact-secondary"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A0A0B4J1T2" version="SP_237" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="C0JKD3" version="SP_237" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="C0JKD4" version="SP_237" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E7EVX6" version="SP_237" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608057" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000169083" version="SP_288" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000374690" version="SP_288" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000612452" version="SP_288" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001091" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001223" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001701" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003073" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003382" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003682" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004879" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" version="SP_288"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005496" version="SP_288"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" version="SP_288"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5VO4" version="SP_288"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3371497" version="SP_288"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-383280" version="SP_288"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4090294" version="SP_288"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5625886" version="SP_288"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5689880" version="SP_288"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8940973" version="SP_288"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000035.2"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000363822"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000504326"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000421155"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000484033"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001011645.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001334990.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001334992.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001334993.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-125N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P10275 original sequence version: 220</attribute>
          <attribute name="remark-internal">DIP protein P10275-1 original sequence version: 213</attribute>
          <attribute name="remark-internal">DIP protein P10275 original sequence version: 216</attribute>
          <attribute name="remark-internal">DIP protein P10275 original sequence version: 143</attribute>
          <attribute name="remark-internal">DIP protein P10275 original sequence version: 174</attribute>
          <attribute name="remark-internal">DIP protein P10275 original sequence version: 169</attribute>
          <attribute name="remark-internal">DIP protein P10275 original sequence version: 188</attribute>
          <attribute name="remark-internal">DIP protein P10275-1 original sequence version: 188</attribute>
          <attribute name="remark-internal">DIP protein P10275 original sequence version: 196</attribute>
          <attribute name="remark-internal">DIP protein P10275 original sequence version: 217</attribute>
          <attribute name="remark-internal">DIP protein P10275-1 original sequence version: 217</attribute>
          <attribute name="remark-internal">DIP protein P10275-1 original sequence version: 207</attribute>
          <attribute name="crc64">A73432C55D39AE06</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4" imexId="IM-21843-1">
        <names>
          <shortLabel>sp1-ar-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9074049" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" refType="component" refTypeAc="MI:0354"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-21843-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="6">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">7b</attribute>
          <attribute name="ligand">R1881</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>