Molecular Connections Molecular Connections Pvt. Ltd. 2/2, Kariappa Road, Basavanagudi, Bangalore -560 004 www.molecularconnections.com Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences. Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences. Mol. Cancer 2010 imex curation Schagdarsurengin U., Richter AM., Hornung J., Lange C., Steinmann K., Dammann RH. Apoptosis - Interactions involving proteins with a function related to apoptosis Cancer - Interactions investigated in the context of cancer reinhard.dammann@gen.bio.uni-giessen.de 06-April-2011: Contacted by JYOTI. orchard Only protein-protein interactions Curation by: Molecular Connections Pvt. Ltd human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Schagdarsurengin U., Richter AM., Hornung J., Lange C., Steinmann K., Dammann RH. Apoptosis - Interactions involving proteins with a function related to apoptosis reinhard.dammann@gen.bio.uni-giessen.de Accepted 2010-Not a month!-7 by ORCHARD. 06-April-2011: Contacted by JYOTI. Mol. Cancer 2010 orchard Only protein-protein interactions imex curation Curation by: Molecular Connections Pvt. Ltd Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences. Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences. Mol. Cancer 2010 imex curation Schagdarsurengin U., Richter AM., Hornung J., Lange C., Steinmann K., Dammann RH. Apoptosis - Interactions involving proteins with a function related to apoptosis Cancer - Interactions investigated in the context of cancer reinhard.dammann@gen.bio.uni-giessen.de 06-April-2011: Contacted by JYOTI. orchard Only protein-protein interactions Curation by: Molecular Connections Pvt. Ltd yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Schagdarsurengin U., Richter AM., Hornung J., Lange C., Steinmann K., Dammann RH. Apoptosis - Interactions involving proteins with a function related to apoptosis reinhard.dammann@gen.bio.uni-giessen.de Accepted 2010-Not a month!-7 by ORCHARD. 06-April-2011: Contacted by JYOTI. Mol. Cancer 2010 orchard Only protein-protein interactions imex curation Curation by: Molecular Connections Pvt. Ltd stk4_human Serine/threonine-protein kinase 4 STK4 MST1 STE20-like kinase MST1 Mammalian STE20-like protein kinase 1 Serine/threonine-protein kinase Krs-2 KRS2 protein protein human Homo sapiens Human METVQLRNPPRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMDVKLKRQESQQREVDQDDEENSEEDEMDSGTMVRAVGDEMGTVRVASTMTDGANTMIEHDDTLPSQLGTMVINAEDEEEEGTMKRRDETMQPAKPSFLEYFEQKEKENQINSFGKSVPGPLKNSSDWKIPQDGDYEFLKSWTVEDLQKRLLALDPMMEQEIEEIRQKYQSKRQPILDAIEAKKRRQQNF 150758EBC5F77D5C q9ns23-2 Ras association domain-containing protein 1 RASSF1A RASSF1 RDA32 protein protein human Homo sapiens Human MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPATHTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRCRALVCLDCCGPRDLGWEPAVERDTNVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG Produced by alternative splicing of isoform D. 73FB7C7D87507D9F rasf3_human Ras association domain-containing protein 3 RASSF3 protein protein human Homo sapiens Human MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREVWKPD 2C8AD10649259811 q8www0-3 Ras association domain-containing protein 5 C NORE1B RASSF5 NORE1 RAPL New ras effector 1 Regulator for cell adhesion and polarization enriched in lymphoid tissues protein protein human Homo sapiens Human MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRSARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVGCLLHP 2657B6DAECD8D6A9 rasf2_human Ras association domain-containing protein 2 RASSF2 KIAA0168 CENP-34 protein protein human Homo sapiens Human MDYSHQTSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISWGLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQMPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKKLMRKYTVLRLMIRQRLEEIAETPATI C29D16376904249E q8www0-1 Ras association domain-containing protein 5 A NORE1A RASSF5 NORE1 RAPL New ras effector 1 Regulator for cell adhesion and polarization enriched in lymphoid tissues protein protein human Homo sapiens Human MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRSARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG DIP protein Q8WWW0-1 original sequence version: 114 DIP protein Q8WWW0-1 original sequence version: 111 DIP protein Q8WWW0-1 original sequence version: 107 4AFBC69B1325CC9E stk3_human Serine/threonine-protein kinase 3 STE20-like kinase MST2 Mammalian STE20-like protein kinase 2 Serine/threonine-protein kinase Krs-1 STK3 MST2 KRS1 protein protein human Homo sapiens Human MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDELDSHTMVKTSVESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCNQNMHEPFPMSKNVFPDNWKVPQDGDFDFLKNLSLEELQMRLKALDPMMEREIEELRQRYTAKRQPILDAMDAKKRRQQNF DIP protein Q13188 original sequence version: 150 DIP protein Q13188 original sequence version: 139 84F598ED3617292C rasf6_human Ras association domain-containing protein 6 RASSF6 protein protein human Homo sapiens Human MLWEETGAAPAPARASDLPYRISSDHLKKEEKMTMMAHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGMLDIFWGVKRPIQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMSEKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRASINGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV 19AF7D4B1ABA5ED6 rasf4_human Ras association domain-containing protein 4 RASSF4 AD037 protein protein human Homo sapiens Human MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIAWGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGERTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEAK 8EB5990165886D99 sav1_human Protein salvador homolog 1 SAV1 WW45 45 kDa WW domain protein protein protein human Homo sapiens Human MLSRKKTKNEVSKPAEVQGKYVKKETSPLLRNLMPSFIRHGPTIPRRTDICLPDSSPNAFSTSGDVVSRNQSFLRTPIQRTPHEIMRRESNRLSAPSYLARSLADVPREYGSSQSFVTEVSFAVENGDSGSRYYYSDNFFDGQRKRPLGDRAHEDYRYYEYNHDLFQRMPQNQGRHASGIGRVAATSLGNLTNHGSEDLPLPPGWSVDWTMRGRKYYIDHNTNTTHWSHPLEREGLPPGWERVESSEFGTYYVDHTNKKAQYRHPCAPSVPRYDQPPPVTYQPQQTERNQSLLVPANPYHTAEIPDWLQVYARAPVKYDHILKWELFQLADLDTYQGMLKLLFMKELEQIVKMYEAYRQALLTELENRKQRQQWYAQQHGKNF DIP protein Q9H4B6 original sequence version: 102 4012C40A8601417A mst1-rassf1a-1 2 4 unspecified role unspecified role unspecified role unspecified role 3 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst1-rassf2-1 2 7 unspecified role unspecified role unspecified role unspecified role 3 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst1-rassf3-1 2 3 unspecified role unspecified role unspecified role unspecified role 5 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst1-rassf4-1 2 11 unspecified role unspecified role unspecified role unspecified role 3 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst1-rassf5a-1 2 8 unspecified role unspecified role unspecified role unspecified role 3 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst1-rassf5c-1 2 6 unspecified role unspecified role unspecified role unspecified role 3 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst1-rassf6-1 2 10 unspecified role unspecified role unspecified role unspecified role 3 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst1-ww45-1 2 3 unspecified role unspecified role unspecified role unspecified role 12 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst2-rassf1a-1 2 9 unspecified role unspecified role unspecified role unspecified role 4 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst2-rassf2-1 2 7 unspecified role unspecified role unspecified role unspecified role 9 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst2-rassf3-1 2 9 unspecified role unspecified role unspecified role unspecified role 5 unspecified role unspecified role unspecified role unspecified role physical association physical association mst2-rassf4-1 2 11 unspecified role unspecified role unspecified role unspecified role 9 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst2-rassf5a-1 2 8 unspecified role unspecified role unspecified role unspecified role 9 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst2-rassf5c-1 2 6 unspecified role unspecified role unspecified role unspecified role 9 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 mst2-rassf6-1 2 10 unspecified role unspecified role unspecified role unspecified role 9 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst2-ww45-2 2 9 unspecified role unspecified role unspecified role unspecified role 12 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 ww45-rassf1a-1 2 12 unspecified role unspecified role unspecified role unspecified role 4 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 ww45-rassf3-1 2 5 unspecified role unspecified role unspecified role unspecified role 12 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 ww45-rassf4-1 2 11 unspecified role unspecified role unspecified role unspecified role 12 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 ww45-rassf5a-1 2 8 unspecified role unspecified role unspecified role unspecified role 12 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 rassf1a-rassf1a-1 2 4 unspecified role unspecified role unspecified role unspecified role 4 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 rassf2-rassf1a-1 2 7 unspecified role unspecified role unspecified role unspecified role 4 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 rassf2-rassf3-1 2 7 unspecified role unspecified role unspecified role unspecified role 5 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 rassf3-rassf3-1 2 5 unspecified role unspecified role unspecified role unspecified role 5 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 rassf3-rassf4-1 2 11 unspecified role unspecified role unspecified role unspecified role 5 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 rassf5c-rassf1a-1 2 6 unspecified role unspecified role unspecified role unspecified role 4 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 rassf5c-rassf2-1 2 6 unspecified role unspecified role unspecified role unspecified role 7 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 rassf5c-rassf4 2 6 unspecified role unspecified role unspecified role unspecified role 11 unspecified role unspecified role unspecified role unspecified role physical association physical association table 2 and additional file 2 mst1-mst2-1 2 3 unspecified role unspecified role unspecified role unspecified role 9 unspecified role unspecified role unspecified role unspecified role physical association physical association additional file 2 mst1-rassf1a-2 1 4 unspecified role unspecified role prey prey undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 3 unspecified role unspecified role bait bait undetermined Undetermined feature position gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association table 2 and fig. 5 mst1-rassf2-2 1 7 unspecified role unspecified role prey prey undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 3 unspecified role unspecified role bait bait undetermined Undetermined feature position gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association table 2 and fig. 5 mst1-ww45-2 1 12 unspecified role unspecified role prey prey undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 3 unspecified role unspecified role bait bait undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undetermined Undetermined feature position gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association table 2 and fig. 5 mst1-rassf3-2 1 5 unspecified role unspecified role prey prey undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 3 unspecified role unspecified role bait bait undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undetermined Undetermined feature position gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association table 2 and fig. 5 mst1-rassf4-2 1 11 unspecified role unspecified role prey prey undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 3 unspecified role unspecified role bait bait undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undetermined Undetermined feature position gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association table 2 and fig. 5 mst1-rassf5c-2 1 6 unspecified role unspecified role prey prey undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 3 unspecified role unspecified role bait bait undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undetermined Undetermined feature position gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association table 2 and fig. 5 rassf6-mst1-1 1 10 unspecified role unspecified role bait bait undetermined Undetermined feature position gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 3 unspecified role unspecified role prey prey undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association table 2 and fig. 5 rassf3-rassf3-2 1 5 unspecified role unspecified role bait bait undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undetermined Undetermined feature position gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 5 unspecified role unspecified role prey prey undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association table 2 and fig. 5 rassf2-mst1-1 1 7 unspecified role unspecified role bait bait undetermined Undetermined feature position gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined sarah_domain required to bind necessary binding region required to bind certain certain sequence position certain certain certain sequence position certain 3 unspecified role unspecified role prey prey undetermined Undetermined feature position flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association additional file 3