IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Trans-Synaptic Interaction of GluRdelta2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum. Trans-Synaptic Interaction of GluRdelta2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum. Cell (0092-8674) 2010 imex curation Uemura T., Lee SJ., Yasumura M., Takeuchi T., Yoshida T., Ra M., Taguchi R., Sakimura K., Mishina M. Apoptosis - Interactions involving proteins with a function related to apoptosis The presynaptic differentiation of cerebellar granule cells (GCs) was induced by treatment with magnetic beads coated with the N-terminal domain of GluRd2 fused to the Fc-domain of human IgG, and then surface proteins of cerebellar GC axons were crosslinked to GluRd2 using nonpermeable 3,30-dithiobis(sulfosuccinimidylpropionate) (DTSSP) for identification by mass spectrometric analysis Source of Grid2 taken from PMID: 7506541, details of constructs in PMID: 19000899. NRX1 exists in 2 forms created by alternative promoter usage, in human and rat but the beta form is missing in UniProtKB for mouse. mishina@m.u-tokyo.ac.jp 21-Dec-2010: Contacted by JYOTI. jyoti Only protein-protein interactions human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Uemura T., Lee SJ., Yasumura M., Takeuchi T., Yoshida T., Ra M., Taguchi R., Sakimura K., Mishina M. Apoptosis - Interactions involving proteins with a function related to apoptosis The presynaptic differentiation of cerebellar granule cells (GCs) was induced by treatment with magnetic beads coated with the N-terminal domain of GluRd2 fused to the Fc-domain of human IgG, and then surface proteins of cerebellar GC axons were crosslinked to GluRd2 using nonpermeable 3,30-dithiobis(sulfosuccinimidylpropionate) (DTSSP) for identification by mass spectrometric analysis Source of Grid2 taken from PMID: 7506541, details of constructs in PMID: 19000899. NRX1 exists in 2 forms created by alternative promoter usage, in human and rat but the beta form is missing in UniProtKB for mouse. mishina@m.u-tokyo.ac.jp Accepted 2010-JUL-30 by JYOTI. 21-Dec-2010: Contacted by JYOTI. Cell (0092-8674) 2010 jyoti Only protein-protein interactions imex curation Trans-Synaptic Interaction of GluRdelta2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum. Trans-Synaptic Interaction of GluRdelta2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum. Cell (0092-8674) 2010 imex curation Uemura T., Lee SJ., Yasumura M., Takeuchi T., Yoshida T., Ra M., Taguchi R., Sakimura K., Mishina M. Apoptosis - Interactions involving proteins with a function related to apoptosis The presynaptic differentiation of cerebellar granule cells (GCs) was induced by treatment with magnetic beads coated with the N-terminal domain of GluRd2 fused to the Fc-domain of human IgG, and then surface proteins of cerebellar GC axons were crosslinked to GluRd2 using nonpermeable 3,30-dithiobis(sulfosuccinimidylpropionate) (DTSSP) for identification by mass spectrometric analysis Source of Grid2 taken from PMID: 7506541, details of constructs in PMID: 19000899. NRX1 exists in 2 forms created by alternative promoter usage, in human and rat but the beta form is missing in UniProtKB for mouse. mishina@m.u-tokyo.ac.jp 21-Dec-2010: Contacted by JYOTI. jyoti Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Uemura T., Lee SJ., Yasumura M., Takeuchi T., Yoshida T., Ra M., Taguchi R., Sakimura K., Mishina M. Apoptosis - Interactions involving proteins with a function related to apoptosis The presynaptic differentiation of cerebellar granule cells (GCs) was induced by treatment with magnetic beads coated with the N-terminal domain of GluRd2 fused to the Fc-domain of human IgG, and then surface proteins of cerebellar GC axons were crosslinked to GluRd2 using nonpermeable 3,30-dithiobis(sulfosuccinimidylpropionate) (DTSSP) for identification by mass spectrometric analysis Source of Grid2 taken from PMID: 7506541, details of constructs in PMID: 19000899. NRX1 exists in 2 forms created by alternative promoter usage, in human and rat but the beta form is missing in UniProtKB for mouse. mishina@m.u-tokyo.ac.jp Accepted 2010-JUL-30 by JYOTI. 21-Dec-2010: Contacted by JYOTI. Cell (0092-8674) 2010 jyoti Only protein-protein interactions imex curation Trans-Synaptic Interaction of GluRdelta2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum. Trans-Synaptic Interaction of GluRdelta2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum. Cell (0092-8674) 2010 imex curation Uemura T., Lee SJ., Yasumura M., Takeuchi T., Yoshida T., Ra M., Taguchi R., Sakimura K., Mishina M. Apoptosis - Interactions involving proteins with a function related to apoptosis The presynaptic differentiation of cerebellar granule cells (GCs) was induced by treatment with magnetic beads coated with the N-terminal domain of GluRd2 fused to the Fc-domain of human IgG, and then surface proteins of cerebellar GC axons were crosslinked to GluRd2 using nonpermeable 3,30-dithiobis(sulfosuccinimidylpropionate) (DTSSP) for identification by mass spectrometric analysis Source of Grid2 taken from PMID: 7506541, details of constructs in PMID: 19000899. NRX1 exists in 2 forms created by alternative promoter usage, in human and rat but the beta form is missing in UniProtKB for mouse. mishina@m.u-tokyo.ac.jp 21-Dec-2010: Contacted by JYOTI. jyoti Only protein-protein interactions in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Uemura T., Lee SJ., Yasumura M., Takeuchi T., Yoshida T., Ra M., Taguchi R., Sakimura K., Mishina M. Apoptosis - Interactions involving proteins with a function related to apoptosis The presynaptic differentiation of cerebellar granule cells (GCs) was induced by treatment with magnetic beads coated with the N-terminal domain of GluRd2 fused to the Fc-domain of human IgG, and then surface proteins of cerebellar GC axons were crosslinked to GluRd2 using nonpermeable 3,30-dithiobis(sulfosuccinimidylpropionate) (DTSSP) for identification by mass spectrometric analysis Source of Grid2 taken from PMID: 7506541, details of constructs in PMID: 19000899. NRX1 exists in 2 forms created by alternative promoter usage, in human and rat but the beta form is missing in UniProtKB for mouse. mishina@m.u-tokyo.ac.jp Accepted 2010-JUL-30 by JYOTI. 21-Dec-2010: Contacted by JYOTI. Cell (0092-8674) 2010 jyoti Only protein-protein interactions imex curation Trans-Synaptic Interaction of GluRdelta2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum. Trans-Synaptic Interaction of GluRdelta2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum. Cell (0092-8674) 2010 imex curation Uemura T., Lee SJ., Yasumura M., Takeuchi T., Yoshida T., Ra M., Taguchi R., Sakimura K., Mishina M. Apoptosis - Interactions involving proteins with a function related to apoptosis The presynaptic differentiation of cerebellar granule cells (GCs) was induced by treatment with magnetic beads coated with the N-terminal domain of GluRd2 fused to the Fc-domain of human IgG, and then surface proteins of cerebellar GC axons were crosslinked to GluRd2 using nonpermeable 3,30-dithiobis(sulfosuccinimidylpropionate) (DTSSP) for identification by mass spectrometric analysis Source of Grid2 taken from PMID: 7506541, details of constructs in PMID: 19000899. NRX1 exists in 2 forms created by alternative promoter usage, in human and rat but the beta form is missing in UniProtKB for mouse. mishina@m.u-tokyo.ac.jp 21-Dec-2010: Contacted by JYOTI. jyoti Only protein-protein interactions mouse-brain-cerebellum Mus musculus brain cerebellum brain_cerebellum [Cerebellar] crosslink cross-linking study crosslink sequence tag sequence tag identification sequence tag Uemura T., Lee SJ., Yasumura M., Takeuchi T., Yoshida T., Ra M., Taguchi R., Sakimura K., Mishina M. Apoptosis - Interactions involving proteins with a function related to apoptosis The presynaptic differentiation of cerebellar granule cells (GCs) was induced by treatment with magnetic beads coated with the N-terminal domain of GluRd2 fused to the Fc-domain of human IgG, and then surface proteins of cerebellar GC axons were crosslinked to GluRd2 using nonpermeable 3,30-dithiobis(sulfosuccinimidylpropionate) (DTSSP) for identification by mass spectrometric analysis Source of Grid2 taken from PMID: 7506541, details of constructs in PMID: 19000899. NRX1 exists in 2 forms created by alternative promoter usage, in human and rat but the beta form is missing in UniProtKB for mouse. mishina@m.u-tokyo.ac.jp Accepted 2010-JUL-30 by JYOTI. Accepted 2010-JUL-30 by JYOTI. 21-Dec-2010: Contacted by JYOTI. Cell (0092-8674) 2010 jyoti Only protein-protein interactions imex curation pafa_mouse Platelet-activating factor acetylhydrolase Pla2g7 Pafah PAF 2-acylhydrolase LDL-associated phospholipase A2 2-acetyl-1-alkylglycerophosphocholine esterase 1-alkyl-2-acetylglycerophosphocholine esterase protein protein mouse Mus musculus Mouse MVPLKLQALFCLLCCLPWVHPFHWQDTSSFDFRPSVMFHKLQSVMSAAGSGHSKIPKGNGSYPVGCTDLMFGYGNESVFVRLYYPAQDQGRLDTVWIPNKEYFLGLSIFLGTPSIVGNILHLLYGSLTTPASWNSPLRTGEKYPLIVFSHGLGAFRTIYSAIGIGLASNGFIVATVEHRDRSASATYFFEDQVAAKVENRSWLYLRKVKQEESESVRKEQVQQRAIECSRALSAILDIEHGDPKENVLGSAFDMKQLKDAIDETKIALMGHSFGGATVLQALSEDQRFRCGVALDPWMYPVNEELYSRTLQPLLFINSAKFQTPKDIAKMKKFYQPDKERKMITIKGSVHQNFDDFTFVTGKIIGNKLTLKGEIDSRVAIDLTNKASMAFLQKHLGLQKDFDQWDPLVEGDDENLIPGSPFDAVTQVPAQQHSPGSQTQN 17C8B4D28F1ADC94 ghc2_mouse Mitochondrial glutamate carrier 2 Slc25a18 Gc2 Glutamate/H(+) symporter 2 Solute carrier family 25 member 18 protein protein mouse Mus musculus Mouse MIACRMSSQDLSISAKLINGGIAGLVGVTCVFPIDLAKTRLQNQQGKDVYRGMTDCLMKTARAEGFLGMYRGAAVNLTLVTPEKAIKLAANDFLRQLLMQDGTQRNLKMEMLAGCGAGICQVVITCPMEMLKIQLQDAGRLAVCHQASASATPTSRPYSTGSTSTHRRPSATLIARELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLGVSELTGKASFTHSFVAGCTAGSVAAVAVTPLDVLKTRIQTLKKGLGEDTYSGVTDCARKLWTQEGPAAFMKGAGCRALVIAPLFGIAQGVYFIGIGERILKCFE 1FC0AD760C44E6FE adt2_mouse ADP/ATP translocase 2 Adenine nucleotide translocator 2 ADP,ATP carrier protein 2 Solute carrier family 25 member 5 Slc25a5 Ant2 Aac2 protein protein mouse Mus musculus Mouse MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIFISWMIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGSKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT DIP protein P51881 original sequence version: 108 0798E04B987EFE20 nrx3b_mouse Neurexin-3-beta Nrxn3 Neurexin III-beta protein protein mouse Mus musculus Mouse MHLRIHPRRSPPRRPAWTLGIWSLFWGCIVSSVWSSSNVASSSSSSPGSHSQQEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTDNERLQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSVSGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTGRSDKSLSTSIFEGGYKAHAPKWESKDFRPNKVSETSRTTTTSLSPELIRFTASSSSGMVPKLPAGKMNNRDLKPQPDIVLLPLPTAYELDSTKLKSPLITSPMFRNVPTANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQASSKSGHKKQKNKDKEYYV 0CB4D38095C2B752 c1qb_mouse Complement C1q subcomponent subunit B C1qb protein protein mouse Mus musculus Mouse MKTQWGEVWTHLLLLLLGFLHVSWAQSSCTGPPGIPGIPGVPGVPGSDGQPGTPGIKGEKGLPGLAGDLGEFGEKGDPGIPGTPGKVGPKGPVGPKGTPGPSGPRGPKGDSGDYGATQKVAFSALRTINSPLRPNQVIRFEKVITNANENYEPRNGKFTCKVPGLYYFTYHASSRGNLCVNLVRGRDRDSMQKVVTFCDYAQNTFQVTTGGVVLKLEQEEVVHLQATDKNSLLGIEGANSIFTGFLLFPDMDA 0F5C33EA2DE2E253 tbb2b_mouse Tubulin beta-2B chain Tubb2b protein protein mouse Mus musculus Mouse MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA 4DC3956EFF880746 bdh_mouse D-beta-hydroxybutyrate dehydrogenase, mitochondrial 3-hydroxybutyrate dehydrogenase Bdh1 Bdh protein protein mouse Mus musculus Mouse MLAARLSRPLSQLPGKALSVRDRENGTRHTLLFYPASFSPDTRRTYASQADAASGKAILITGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGDAGVKELDSLKSDRLRTIQLNVCNSEEVEKAVETIRSGLKDPEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGIEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDDLPEVVRKDYGRKYFDEKIAKMETYCNSGSTDTSSVINAVTHALTAATPYTRYHPMDYYWWLRMQIMTHFPGAISDKIYIH B72B0550713EDB7F ef1a1_mouse Elongation factor 1-alpha 1 Eukaryotic elongation factor 1 A-1 Elongation factor Tu Eef1a1 Eef1a protein protein mouse Mus musculus Mouse MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGSASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK DIP protein P10126 original sequence version: 149 71072871DE7405DC srcn1_mouse SRC kinase signaling inhibitor 1 p140Cap SNAP-25-interacting protein Srcin1 Kiaa1684 P140 p130Cas-associated protein protein protein mouse Mus musculus Mouse MQPWQCLRRFALAWWERTAEGRARSPREEVGPRDPGGRGEPDPERSSPPMLSADDAEYPREYRTLGGGGGGGSGGRRFSNVGLVHTSERRHTVIAAQSLEALSGLQKADADRKRDAFMDHLKSKYPQHALALRGQQDRMREQVGGWTVDPVCLLSSLCSHLHGDSTPSGAGQPAQQPNYWSFKTRSSRHTQGAQPGLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSPGVLFLQFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVFYELEDVRDIQDRSIIKIYRKEPLYAAFPGSHLTNGDLRREMVYASRESSPTRRLNNLSPASHLASSSPPPGLPSGLPSGLPSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPTGQGVSPSPSAILERRDVKPDEDLAGKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAETHSHTRARAACTSGVPCALSAPTPLPRCSPTWRTRCTRRALAALYGDGYGFRLPPSSPQKLADVSAPSGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKARSTGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKVEGSNGAATPSAPVCGSGSKSSGATPVSGPPPPSASSTPAGQPTAVSRLQMQLHLRGLQNSASDLRGQLQQLRNVQLQNQESVRALLKPTEADVSMRVSEAARRQEDPLQRQRTLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVAHNHRLMPGPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEVEAVKFLKEEPQRLDGLLKRCRGVTDTLAQIRRQVDEGMWPPPNNLLNQSPKKVAAETDFSKGLDFEIPPPSPPLNLHELSGPAEGTPLTPKSTNPTKCLDASSKRNTDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKTHPGPAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLTTTRTGEVVVTSKKDSVFIKKAESEELEVQKPQVKLRRAVSEVVRPASTPPIMASAIKDEDDEERIIAELESGGSSVPPMKVVTPGASRLKAAQGPAGSPDKGKHGKQRTEYMRIQAQQQATKPSKEVSGPNETSSPGSEKPSGSRTSIPVLTSFGARNSSISF 85F394C9523F78C0 rs3_mouse 40S ribosomal protein S3 Rps3 protein protein mouse Mus musculus Mouse MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDPSGKIGPKKPLPDHVSIVEPKDEILPTTPISEQKGGKPEPPAMPQPVPTA 6B9BB34FDEE04AAF sfxn1_mouse Sideroflexin-1 Sfxn1 protein protein mouse Mus musculus Mouse MSGEVPPNINIKEPRWDQSTFIGRASHFFTVTDPRNILLTNEQLENARKVVHDYRQGIVPAGLTENELWRAKYAYDSAFHPDTGEKMTLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKRVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGTRLGESTNAAKQAITQVVISRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVTLVGFCLVFATPLCCALFPQKSSMSVTSLEDELQASIQRTHPEIRRVYFNKGL E3B055CB03CEDFA7 ibp5_mouse Insulin-like growth factor-binding protein 5 Igfbp5 Igfbp-5 protein protein mouse Mus musculus Mouse MVISVVLLLLAAYAVPAQGLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYGEQTKIERDSREHEEPTTSEMAEETYSPKVFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRVIPAPEMRQESEQGPCRRHMEASLQEFKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHAFDSSNVE F55A58729861F6F0 apoe_mouse Apolipoprotein E Apoe protein protein mouse Mus musculus Mouse MKALWAVLLVTLLTGCLAEGEPEVTDQLEWQSNQPWEQALNRFWDYLRWVQTLSDQVQEELQSSQVTQELTALMEDTMTEVKAYKKELEEQLGPVAEETRARLGKEVQAAQARLGADMEDLRNRLGQYRNEVHTMLGQSTEEIRARLSTHLRKMRKRLMRDAEDLQKRLAVYKAGAREGAERGVSAIRERLGPLVEQGRQRTANLGAGAAQPLRDRAQAFGDRIRGRLEEVGNQARDRLEEVREHMEEVRSKMEEQTQQIRLQAEIFQARLKGWFEPIVEDMHRQWANLMEKIQASVATNPIITPVAQENQ 3B36FA897CC34170 ptprs_mouse Receptor-type tyrosine-protein phosphatase S Ptprs Receptor-type tyrosine-protein phosphatase sigma PTPNU-3 protein protein mouse Mus musculus Mouse MAPTWSPSVVSVVGPVGLFLVLLARGCLAEEPPRFIREPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIDFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITIHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAPRQESVIKYELLFREGDRGREVGRTFDPTTAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPADAAEDPVLGYRLQFGREDAAPATLELAAWERRFAAPAHKGATYVFRLAARGRAGLGEEAAAALSIPEDAPRGFPQILGAAGNVSAGSVLLRWLPPVPAERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLRGLRPETAYELRVRAHTRRGPGPFSPPLRYRLARDPVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSVAPKPDNDGFIVVYLPDGQSPVTVQNYFIVMVPLRKSRGGQFPVLLGSPEDMDLEELIQDISRLQRRSLRHSRQLEVPRPYIAARFSILPAVFHPGNQKQYGGFDNRGLEPGHRYVLFVLAVLQKNEPTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGMLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYAT 725C016196E22D1A eln_mouse Elastin Eln Tropoelastin protein protein mouse Mus musculus Mouse MAGLTAVVPQPGVLLILLLNLLHPAQPGGVPGAVPGGLPGGVPGGVYYPGAGIGGLGGGGGALGPGGKPPKPGAGLLGTFGAGPGGLGGAGPGAGLGAFPAGTFPGAGALVPGGAAGAAAAYKAAAKAGAGLGGVGGVPGGVGVGGVPGGVGVGGVPGGVGVGGVPGGVGGIGGIGGLGVSTGAVVPQVGAGIGAGGKPGKVPGVGLPGVYPGGVLPGTGARFPGVGVLPGVPTGTGVKAKAPGGGGAFAGIPGVGPFGGQQPGVPLGYPIKAPKLPGGYGLPYTNGKLPYGVAGAGGKAGYPTGTGVGSQAAAAAAKAAKYGAGGAGVLPGVGGGGIPGGAGAIPGIGGIAGAGTPAAAAAAKAAAKAAKYGAAGGLVPGGPGVRLPGAGIPGVGGIPGVGGIPGVGGPGIGGPGIVGGPGAVSPAAAAKAAAKAAKYGARGGVGIPTYGVGAGGFPGYGVGAGAGLGGASPAAAAAAAKAAKYGAGGAGALGGLVPGAVPGALPGAVPAVPGAGGVPGAGTPAAAAAAAAAKAAAKAGLGPGVGGVPGGVGVGGIPGGVGVGGVPGGVGPGGVTGIGAGPGGLGGAGSPAAAKSAAKAAAKAQYRAAAGLGAGVPGFGAGAGVPGFGAGAGVPGFGAGAGVPGFGAGAGVPGFGAGAVPGSLAASKAAKYGAAGGLGGPGGLGGPGGLGGPGGLGGAGVPGRVAGAAPPAAAAAAAKAAAKAAQYGLGGAGGLGAGGLGAGGLGAGGLGAGGLGAGGLGAGGLGAGGLGAGGGVSPAAAAKAAKYGAAGLGGVLGARPFPGGGVAARPGFGLSPIYPGGGAGGLGVGGKPPKPYGGALGALGYQGGGCFGKSCGRKRK 7C340F2FFFDC92E5 nrx1b_mouse Neurexin-1-beta Nrxn1 Neurexin I-beta protein protein mouse Mus musculus Mouse MYQRMLRCGADLGSPGGGSGGGAGGRLALIWIVPLTLSGLLGVAWGASSLGAHHIHHFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRVGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV F118A9053BAB4E21 loc97081_mouse_prote LOC97081 protein protein mouse Mus musculus Mouse An amino acid sequence which is not represented in UniProt kcc2b_mouse Calcium/calmodulin-dependent protein kinase type II subunit beta Camk2b Camk2d protein protein mouse Mus musculus Mouse MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSSAITSPKGSLPPAALEPQTTVIHNPVDGIKESSDSTNTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ DIP protein P28652 original sequence version: 88 8A7962A6495FD0D0 adt1_mouse ADP/ATP translocase 1 Slc25a4 Anc1 Ant1 Adenine nucleotide translocator 1 ADP,ATP carrier protein 1 Solute carrier family 25 member 4 ADP,ATP carrier protein, heart/skeletal muscle isoform T1 Aac1 protein protein mouse Mus musculus Mouse MGDQALSFLKDFLAGGIAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDPKNVHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTLDCWRKIAKDEGANAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV 3A849FEAB0981462 ghc1_mouse Mitochondrial glutamate carrier 1 Glutamate/H(+) symporter 1 Solute carrier family 25 member 22 Slc25a22 Gc1 protein protein mouse Mus musculus Mouse MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYASMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLPKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQAQLSAQGGAQPSVEAPAPPRPTATQLTRDLLRNHGIAGLYKGLGATLLRDVPFSIVYFPLFANLNQLGRPSSEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLERGVNEDTYSGFLDCARKIWRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESLLGLLQEPQA CCAED09AB4CF73AE syn2_mouse Synapsin-2 Synapsin II Syn2 protein protein mouse Mus musculus Mouse MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPAPGPGAATASAATSAASPGPERRPPPAQAPAPQPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPSAASRKAKVLLVVDEPHTDWAKCFRGKKILGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRPDFVLIRQHAFGMAENEDFRHLVIGMQYAGLPSINSLESIYNFCDKPWVFAQMVAIFKTLGGEKFPLIEQTYYPNHREMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQTYATAEPFIDAKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDACSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITDLVISKMNQLLSRTPALSPQRPLTTQQPQSGTLKEPDSSKTPPQRPPPQGGPGQPQGMQPPGKVLPPRRLPSGPSLPSSSSSSSSSSSSSSAPQRPGGPTTTHGDASSSSNSLAEAQAPQAAPAQKPQPHPQLNKSQSLTNAFSFSESSFFRSSANEDEAKAETIRSLRKSFASLFSD 2B1B6A7453E286FC sfxn3_mouse Sideroflexin-3 Sfxn3 protein protein mouse Mus musculus Mouse MGDLPLNINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGEQLEASRNIVQNYRAGVATPGLTEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRSGDAPITVQQLGTAYVSATTGAVATALGLKSLTKHLPPLVGRFVPFAAVAAANCINIPLMRQRELQVGIPVTDEAGQRLGHSVTAAKQGIFQVVISRIGMAIPAMAIPPVIMNTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQRSSIHVTRLEPELRAQIQAQNPSIDVVYYNKGL 9B9816A54B23F4EC vime_mouse Vimentin Vim protein protein mouse Mus musculus Mouse MSTRSVSSSSYRRMFGGSGTSSRPSSNRSYVTTSTRTYSLGSALRPSTSRSLYSSSPGGAYVTRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAESTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHDEEIQELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESNEYRRQVQSLTCEVDALKGTNESLERQMREMEENFALEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPTFSSLNLRETNLESLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE A94EECEA6D70C899 g3p_mouse Glyceraldehyde-3-phosphate dehydrogenase Gapdh Gapd Peptidyl-cysteine S-nitrosylase GAPDH protein protein mouse Mus musculus Mouse MVKVGVNGFGRIGRLVTRAAICSGKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMASKE DIP protein P16858 original sequence version: 160 F25131EFFA9F2BD6 cbln1_mouse Cerebellin-1 Cbln1 Precerebellin Brain protein D3 protein protein mouse Mus musculus Mouse MLGVVELLLLGTAWLAGPARGQNETEPIVLEGKCLVVCDSNPTSDPTGTALGISVRSGSAKVAFSAIRSTNHEPSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPRKGIYSFNFHVVKVYNRQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVLIQMEKGDRAYLKLERGNLMGGWKYSTFSGFLVFPL A23C796C7D11BE5F cn37_mouse 2',3'-cyclic-nucleotide 3'-phosphodiesterase Cnp Cnp1 protein protein mouse Mus musculus Mouse MNTSFTRKSHTFLPKLFFRKMSSSGAKEKPELQFPFLQDEDTVATLHECKTLFILRGLPGSGKSTLARLILEKYHDGTKMVSADAYKIIPGSRADFSEAYKRLDEDLAGYCRRDIRVLVLDDTNHERERLDQLFEMADQYQYQVVLVEPKTAWRLDCAQLKEKNQWQLSADDLKKLKPGLEKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEPKEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYGKGKPVPIHGSRKGGAMQICTII 2FAFFDE5F0E99EAB tpa_mouse Tissue-type plasminogen activator Plat protein protein mouse Mus musculus Mouse MKRELLCVLLLCGLAFPLPDQGIHGRFRRGARSYRATCRDEPTQTTYQQHQSWLRPMLRSSRVEYCRCNSGLVQCHSVPVRSCSEPRCFNGGTCQQALYFSDFVCQCPDGFVGKRCDIDTRATCFEEQGITYRGTWSTAESGAECINWNSSVLSLKPYNARRPNAIKLGLGNHNYCRNPDRDLKPWCYVFKAGKYTTEFCSTPACPKGKSEDCYVGKGVTYRGTHSLTTSQASCLPWNSIVLMGKSYTAWRTNSQALGLGRHNYCRNPDGDARPWCHVMKDRKLTWEYCDMSPCSTCGLRQYKRPQFRIKGGLYTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWVLSAAHCFLERFPPNHLKVVLGRTYRVVPGEEEQTFEIEKYIVHEEFDDDTYDNDIALLQLRSQSKQCAQESSSVGTACLPDPNLQLPDWTECELSGYGKHEASSPFFSDRLKEAHVRLYPSSRCTSQHLFNKTVTNNMLCAGDTRSGGNQDLHDACQGDSGGPLVCMINKQMTLTGIISWGLGCGQKDVPGVYTKVTNYLDWIHDNMKQ 0A158A5A273CFAA0 eci2_mouse Enoyl-CoA delta isomerase 2 Eci2 Dodecenoyl-CoA isomerase Delta(3),delta(2)-enoyl-CoA isomerase Peci Peroxisomal 3,2-trans-enoyl-CoA isomerase protein protein mouse Mus musculus Mouse MAAVTWSRARCWCPSVLQVFRLQVAKLHLGRPTMRASQQDFENALNQVKLLKKDPGNEVKLRLYALYKQATEGPCNMPKPGMLDFVNKAKWDAWNALGSLPKETARQNYVDLVSSLSSSSEAPSQGKRGADEKARESKDILVTSEDGITKITFNRPTKKNAISFQMYRDIILALKNASTDNTVMAVFTGTGDYYCSGNDLTNFTSATGGIEEAASNGAVLLRDFVNSFIDFPKPLVAVVNGPAVGISVTLLGLFDAVFASDRATFHTPFSQLGQSPEACSSYTFPKMMGSAKAAEMLLFGKKLTAREAWAQGLVTEVFPESTFETEVWTRLKTYAKLPPNAMRISKELIRKNEKEKLYAVNAEECTTLQARWLSEECMNAIMSFVSRKPKL 0B93D3908DF77AF8 grid2_mouse Glutamate receptor ionotropic, delta-2 Grid2 protein protein mouse Mus musculus Mouse MEVFPLLLFLSFCWSRTWDLATADSIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTLSVRPPVYLNEVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENNINKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINEEINDVDVQELVRRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSSLCDPKDPFAQNMEISNLYIYDTVLLLANAFHKKLEDRKWHSMASLSCIRKNSKPWQGGRSMLETIKKGGVNGLTGDLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLENNMRGVVLRVVTVLEEPFVMVSENVLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRAEKTVDMFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTITRIESSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHGSPYRDVFSQRILELQQSGDMDILKHKWWPKNGQCDLYSSVDAKQKGGALDIKSLAGVFCILAAGIVLSCLIAVLETWWSRRKGSRVPSKEDDKEIDLEHLHRRVNSLCTDDDSPHKQFSTSSIDLTPLDIDTLPTRQALEQISDFRNTHITTTTFIPEQIQTLSRTLSAKAASGFAFGSVPEHRTGPFRHRAPNGGFFRSPIKTMSSIPYQPTPTLGLNLGNDPDRGTSI A456166CC782A44B fat2_mouse Protocadherin Fat 2 Fat2 Fath2 Kiaa0811 FAT tumor suppressor homolog 2 protein protein mouse Mus musculus Mouse MTLVLLGVAMVLLHRAACEKPLEETITPLTWRFTHSLYNATIYENSAPKTYVESPVKMGMYLAEPHWVVKYRIISGDAAGVFKTEEHVVGNFCFLRIRTKSSNTALLNREVRDSYTLVVQASDKSLEFEALTQVVVHILDQNDLKPLFSPPSYRFTISEDRPLKSPICKVTATDADLGQNAEFYYAFNARSEVFAIHPTSGVVTVAGKLNVTWRGKYELQVLAVDRMRKISEGNGFGNLAPLVIYVEPVHRKPPVITLVVLNPPEGDEGDIYATVTVDTNGSGAEVDSLEVVGGDPGKYFKVLKSYAQGNEFNLVAVRDINWAEHLHGFNISLQTHSRSRFPSRSIIRAFHLPPYTLANLRFEKAVYRVKLSEFSPPGSRVALVRVTTALPTLRYALKPSSGSTVFKLNARTGLITTTKPVDFHEQNQYQLHVKTSLGQATTTVIIDIVDCNNHAPVFNRSSYEGTLDENIPPGTSVLTVTATDQDHGDNGHITYSIAGPKAVPFSIDPYLGVISTTKSMDYELMKRIYTFRVRASDWGSPFRQEKEVSVSLRLKNLNDNQPMFEEVNCTVSLRQDAPVGKSIMAVSAIDMDELQNLKYEIVSGNEQDYFHLNHFSGVISLKRSFMNLTAVRPTVYSLKITASDGKNYASPTTLKVTVVKDPRSEVPVQCDKTGVLTHITKTILQSAGLQGQEMGEEDFTSLGNYQINHHAPQFEDHFPQSIDILEQVPVNTPLAHLAATDPDPGFHGRLVYVIADGNEEGCFDIELETGLLTVAAALDYETTSFYVLNVTVYDLGTPPKSSWKLLTVTVKDWNDKPPRFPPGGYQLTISEDTEVGTTVAELKTRDTDSEDNGRVRYTLLTPTEKFSLHPLTGELVVTGQLDRESEPQYILKAEARDQPTKGHQLFSVTDVIVTLEDINDNPPQCITEHSSLKVPEDMPLGTVLTFLDASDPDLGPAGEVKYILVDDVHGTFRVDPMTGALSLEKELDFERRAGYNLSFWASDSGRPLARRTLCHVEVLVMDVNENLHSPHFSSFVYQGQVQENSPAGTQVMVVTAQDDDSGLDGELQYFLRAGTGLEAFSINQDTGMLETLAPLDREFTPYYWLTVLAVDRGSVPLSAVTEVYIEVTDINDNIPSMSRPVFYPSVKEDAPLGTSVLQLEAWDPDFSSQGKLTFNLTSGNHMGHFIVHPFTGLLSTAKQLDRENKDEYVLEVTVQDNGDPPLRSTSRVVVCVLDVNDNSPMFSHKLFNVRLSERLSPLSPEPVYRLVASDPDEGLNGSITYSIEESDEESFRIDPVTGVVSSSSTFAAGEYNILTIKATDSGQPALSTSVRLHIEWIPQPRPSSIPLSFDESHYSFAVMETDPVNHMLGVISVEGRPGLFWFHISDGDKDMDFDIEKTTGSIVIARPLDTRRKSSYNLTVEVTDGFHTIATQVHILMIANINHHRPQFLQDHYDIRVPQDTLPGVELLRVQATDQDHGKGLIYTIHSSRDPGSANLFQLDPSSGVLVTVGTLDLHSGPSQHILTVMVRDQEMPIKRNFVWVTIHVEDGNLHSPHFTQPRYEANVPDTTTPGTELLQVRAVDADRGANAEVHYSFLKGNSEGFFNIDSLLGIITVAQRLDHVHLNRHALTVKAEDQGSPQRHDLAMVVVHVHPSDSSAPIFSKDEYFIEIPESVPIGSPILLISAASSSDVTYELREGNKNSVFSMNSYSGLISTQKRLDHEKVSSYQLKIRGSNMAGVFTEVVALVYIIDENDNAPAFLKSTFVGHISEAAPLHSLILGEDNSPLVIRASDSDQEANSLLVYKILEPEALKFFKIDPSMGTLTITSELDYETTPLFQFSIYVHDQGTPILFAPRSARVIIHVRDVNDSPPRFSEQIYEVAVVEPIHPGMELLTVQAEDNDSKVTYSIKTSNTDEAVTIHPITGQISVVNPAALRLFPKLNIRAFDGLYQDTAVVKISLTQALDKSLQFDQDIYRARVTENTPHSNVLVILGVHGNHLNDTLSYFLLNGTDLFHMVKSAGVLQTRGVTFDREQQDTHEVAVEVRDNRVPRRVAQALVRVSVEDVNDNIPEFQHLPYYTVIQDGTEPGDVLFQVSATDKDLGANGTVTYGFAEDYAYFRIDPYVGDISLKKPFDYQALNKYHLRVTARDAGTPPLQTEVEVHVTVRNKSNPLFQSPYYKVKVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKNKHVFTVRATDTALGSFSEATVEVLVEDINDNPPTFSQLVYSTSVSEGSPAQTPVIQLLASDQDSGQNQDVSYQIVEDGSDVSKFFRINGSTGEMFTIQELDYEAHQHFRVKVRATDRGDPPLTGETLVVVNVSDINDNPPEFREPQYEANVSELATCGHLVLKVQALDPDIGDTSRLEYLILSGNQDRHFSINSTSGIISMFNLCKKQLDSSYNLRVGASDGVFQATVPVYINTTNANKYSPEFQQNVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGERFFINPSGQITTLQKLDRENSTERVIAIKIMARDGGGKVAFCTVKIILTDENDNAPQFKASGYTVSIPSNVSRDSPIIQVLAYDADEGRNADVTYSVDSTEDLAEEIIEVNPTTGVVKVKESLVGLENKAVDFNIKAQDGGPPHWDSLVPVRLQVVPNEIPLPKFSEPLYTFSASEDLPEGSEIGSVKAVAAQDPIIYSLVQGTTPESNSDDVFSLDQDTGVLKVKKAMDHESTKWYQIDLMAHCPHEDTDLVSLVSVNIQVEDVNDNRPVFEADPYKAFLTENMPGGTTVIQVTANDQDTGSDGQVSYRLSVEPGSNIHQLFAVDSESGWITTLQELDCETQQTYRFYVVAFDHGQTIQLSSQALVEVSITDENDNPPRFASEDYRGSVVENNEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFSISQVGDEWRITSRKTLDREHIAKYLLRITASDGKFQASVPVEVFVLDINDNSPQCSQLLYTGKVREDVTPGHFILKVSAIDVDMDTNAQITYSLHGPGAQEFKLDPHTGELTTLSVLDRERKDVYNLVAKATDGGGQSCQAEVTLHIEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGVNAQVVYSLTDSADGQFSIDATSGVIRLEKPLQVRSSSAVELTVRASDLGTPIPLSTLGTVTVSIVGLEDYLPIFLNSEHSTQVPEDALIDMEVLYLATLTRPGSEKTGYHITGGNEQGKFRLDAHTGILYVNGSLDFETNPKYFLSIECSRKSSSSLSDVTTIVINVTDVNEHHPRFTHDLYTVRVLENAIVGDVILTVSASDDDGPVNSVITYSLVGGNQLGHFTIDPKKGKLQVAKALDWEQTPSYSLRIRATDSGQPPLHEDTEVAVEVVDVNDNPPRFFQLNYSTAVQENSPIGIKVLQLILDDPDSPQNGPPYFFRITEGNTGSVFRVTPDGWLVTAGSLSRRAQEWYQLHIEVSDSGLPPLSSSTLVRVHITEQSRYPPSTLPLEIFITKGEEEFQGGMVGKIHATDRDPQDTLTYSLDREGSLGKYFTVGASDGKIIASQGLPRGRYLFNVTVSDGTFTTTTGVHVHVWHMGQEAPQQAVWLGFHQLTPEELVSDHWRNLQRFLSNILDIKRANIHLASLQPAEVTAGVDVLLAFEGHSGTSYDLQELASAIAHSAKEMEHSVGIQMRSALPVVPCQGPSCQDQTCQETVSLEPRVGPSYSTARLSILTPRHHLGKNCSCNGTTWRFSGQSYMRYRPLEAQNWQIHFYLKTLQPWALLMFTNETASISLKLANGFLHLEYRCPGGFYGNLSSHRPVNDGQWHSMLLEERDTSVHLLVDITDNTSLVIPEECQGLRTERHLLLGGLVPSNPSSNVSLGFEGCLDAVVVNSERLELLGHRKKMAGYLETWALSQCCWPGTTCSQNPCLNGGSCSPALGSGYLCRCPPLFSGRNCELGRENCTSAPCQEGGTCVSSPEGTSCSCPHPYTGDRCEMEARGCSGGHCLITPEIKRGDWGQQEFLVIIVALPLLIIATVGLLLYCRRCKSHKPVAMEDPDLLARSIGVDTQASPAIELDPLNAGSCNDLNQLEPSKTSVPNELVTFGPSSKQRPMVCSVPPRLPPAVVSSHPGHEPIIKRTWSGEELVYPSGAAVWPPTYSRKEHWEYPHPEAMQGPLPPSPRRHVSPAVMPDPAGLYGGFPFPLELENKRAPLPPRYSNQNLEDLIPPRPPSPREHLLAPCLNEYTAISYYHSQFRQGGGGPCLAEGGYKGVSMRLSRAGPSYADCEVNGGPAPGRSQPRAPPNYEGSDMVESDYGSCEEVMF 72F9DADAAA5467D5 q91va7_mouse Isocitrate dehydrogenase [NAD] subunit, mitochondrial Idh3b protein protein mouse Mus musculus Mouse MAALSNVRWLTRAVLAARNSGAWRGLGTSTAHAASQSQAQDVRVEGAFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFKEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIYTPMEYKGELASYDMQLRRKLDLFANVVHVKSLPGYKTRHNNLDLVIIREQTEGEYSSLEHESAKGVIECLKIVTRTKSQRIAKFAFDYATKKGRSKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSATNMLRHLNLEYHSSMIADAVKKVIKAGKVRTRDMGGYSTTTDFIKSVIGHLHPHGG 49162354C2A4DFBE ttc9b_mouse Tetratricopeptide repeat protein 9B Ttc9b protein protein mouse Mus musculus Mouse MQRGALSPVLMLSAAPEPPPRPPPALSPPGPGSAPRHGSARSGPAPEPSGGLAAALDSSLRAAVAFKAEGQRCYREKKFREAIGKYHRALLQLKAAQGARPGGLPTPSPGPTTSPGPARLSEEQRRLVENTEVECYDSLTACLLQSELVNYERVREYCLKVLEKQQGNFKATYRAGIAFYHLGDYARALRYLQEARSREPTDTNVLRYIQLTQLKMNRCSLQREDSDGGTGGPARNVVG 1C2BF350E54717F6 nrx2b_mouse_protein Neurexin-2-beta protein protein mouse Mus musculus Mouse An amino acid sequence which is not represented in UniProt Neurexin-2-beta is a set of NRXn2 isoforms produced by alternative promoter usage - proteins currently only in TrEMBL. nrx1a_mouse Neurexin-1 Nrxn1 Neurexin I-alpha Kiaa0578 Neurexin-1-alpha protein protein mouse Mus musculus Mouse MGTALVQRGGCCLLCLSLLLLGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRVGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV 412281FE441F0EFC sfxn5_mouse Sideroflexin-5 Sfxn5 protein protein mouse Mus musculus Mouse MADTATTASAASAAASAPNASTDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTEKRLREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAVGLNVLVQKANKFTPATRLLVQRFVPFPAVASANICNVVLMRYGELEEGIDVLDADGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVHSLVCLAAFGLALPLAISLFPQMSEIETSQLEPEIARATSSRTVVYNKGL 9BDB8261D5EF79D9 q3ugz9_mouse Nrxn2 protein protein mouse Mus musculus Mouse MALGSRWQPPPQLPPLLLLLALAAGVRGLEFGGGPGQWARYARWAGAASTGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANLKLGERPPALLGSQGLRGAAADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAGRGGAGDVRQPTKGKEEFVATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVTISLDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGAGVGSHSSTQRADYFAMELLDGYLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGESEVLDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCRNGGICREGWNRFVCDCIGTGFLGRVCEREATVLSYDGSMYMKIMLPTAMHTEAEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMRLTVNLDCLRVGCAPSKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGAHTRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPSTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTMRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPSSGGPCQAERDDSDCEEPVEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGVPTAFEPRRPPPLRPGVTSAPGFPRLPTANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV CB782BB13128EF12 roa1_mouse Heterogeneous nuclear ribonucleoprotein A1 Hnrpa1 hnRNP core protein A1 Helix-destabilizing protein HDP-1 Single-strand-binding protein Topoisomerase-inhibitor suppressed Hnrnpa1 Fli-2 Tis protein protein mouse Mus musculus Mouse MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF 59485C9FA1FF8AE1 ppt1_mouse Palmitoyl-protein thioesterase 1 Palmitoyl-protein hydrolase 1 Ppt1 Ppt Cln1 protein protein mouse Mus musculus Mouse MASSCSRRLLAAALLPWCCAAWALGHLDPPSPPPLVIWHGMGDSCCNPMSMGVIKKMVEKEIPGIYVLSLEIGKNMMEDVENSFFLNVNVQVNMVCQILEKDPKLQQGYNAIGFSQGGQFLRAVAQRCPTPPMMTLISVGGQHQGVFGLPRCPGESSHICDFIRKSLNAGAYSKLVQERLVQAQYWHDPIKESVYRNYSIFLADINQERCVNESYKKNLMALKKFVMVKFFNDSIVDPVDSEWFGFYRSGQAKETIPLQESTLYTEDRLGLKKMDKAGKLVFLAKEGDHLQISKEWFTAHIIPFLK CC7D9B65ECAF46A8 q3ts89_mouse PIP49_C domain-containing protein Dipk2a 1190002N15Rik protein protein mouse Mus musculus Mouse MVAVNYVGEELWSYFNAPWEKRVDLAWQLMEIAEQLTNNDFEFALYLLDVSFDNFAVGPRDGKVIIVDAENVLVADKRLIRQNKPENWDVWYESKFDDCDKEACLSFSKEILCARVTVDHNYYAVCQNLLSRHATWRGTSGGLLHDPPSEIAKDGRLEALLDECTNPKKRYGRFQAAKELRGYLAQLSHNVR DB46A91974DC4AE6 grid2-adt2-1 4 7 unspecified role unspecified role prey prey 33 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. 21 unspecified role unspecified role prey prey 43 unspecified role unspecified role prey prey 18 unspecified role unspecified role prey prey 39 unspecified role unspecified role prey prey 14 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey 36 unspecified role unspecified role prey prey 9 unspecified role unspecified role prey prey 6 unspecified role unspecified role prey prey 10 unspecified role unspecified role prey prey 22 unspecified role unspecified role prey prey 28 unspecified role unspecified role prey prey 41 unspecified role unspecified role prey prey 12 unspecified role unspecified role prey prey 26 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 27 unspecified role unspecified role prey prey 15 unspecified role unspecified role prey prey 32 unspecified role unspecified role prey prey 40 unspecified role unspecified role prey prey 29 unspecified role unspecified role prey prey 31 unspecified role unspecified role prey prey 38 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 24 unspecified role unspecified role prey prey 34 unspecified role unspecified role prey prey 30 unspecified role unspecified role prey prey 16 unspecified role unspecified role prey prey 35 unspecified role unspecified role prey prey 5 unspecified role unspecified role prey prey 17 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey 19 unspecified role unspecified role prey prey 42 unspecified role unspecified role prey prey association association Supplementary Table 1 grid2-nrxn1-1 1 29 unspecified role unspecified role ancillary ancillary region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 33 unspecified role unspecified role neutral component neutral component region Fc fusion fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 20 unspecified role unspecified role neutral component neutral component region v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined s4 splicing region required to bind necessary binding region required to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined extracellular region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined colocalization colocalization GluRδ2 Interacts with β-NRXN in the Presence of Cbln1 Figs. 1D, 2A, 2B grid2-nrxn2-1 1 33 unspecified role unspecified role neutral component neutral component region Fc fusion fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 37 unspecified role unspecified role neutral component neutral component region v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined s4 splicing region required to bind necessary binding region required to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 29 unspecified role unspecified role ancillary ancillary region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined colocalization colocalization GluRδ2 Interacts with β-NRXN in the Presence of Cbln1 Figs. 1D, 2A grid2-nrxn3-1 1 33 unspecified role unspecified role neutral component neutral component region Fc fusion fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 29 unspecified role unspecified role ancillary ancillary region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 8 unspecified role unspecified role neutral component neutral component region Fc fusion fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined s4 splicing region required to bind necessary binding region required to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined colocalization colocalization GluRδ2 Interacts with β-NRXN in the Presence of Cbln1 Fig. 2A grid2-nrxn1-2 3 29 unspecified role unspecified role prey prey region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. 33 unspecified role unspecified role bait bait region Fc fusion fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. 20 unspecified role unspecified role prey prey c-terminal alk phosphatase tag alkaline phosphatase tag alk phosphatase tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range c-terminal myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range extracellular region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined c-terminal his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range s4 splicing region required to bind necessary binding region required to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. association association Pulldown assay of the interaction of GluRδ2-NTD-Fc and NRXN1β-ECD-AMH in the presence of HA-Cbln1. Fig. 3A, Supp. Fig. 3A cbln1-grid2-1 3 29 unspecified role unspecified role prey prey region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. 33 unspecified role unspecified role bait bait region Fc fusion fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. physical association physical association However, NRXN1β(�S4)-ECD-AMH was not coprecipitated by Protein A with GluRδ2-NTD-Fc and HA-Cbln1 (Figure S3A) Fig. 3C, Supp. Fig. 3A grid2-cbln1-1 1 29 unspecified role unspecified role neutral component neutral component region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 33 unspecified role unspecified role neutral component neutral component region Fc fusion fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined colocalization colocalization Binding of soluble HA-Cbln1 to HEK293T cells transfected with GluRδ2 Figs. 3B cbln1-grid2-2 2 29 unspecified role unspecified role prey prey region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. 33 unspecified role unspecified role bait bait region Fc fusion fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. direct interaction direct interaction However, NRXN1β(�S4)-ECD-AMH was not coprecipitated by Protein A with GluRδ2-NTD-Fc and HA-Cbln1 (Figure S3A) Fig. 3C, Supp. Fig. 3A pH 7.4, Temp=25C cbln1-nrxn1-1 1 20 unspecified role unspecified role neutral component neutral component region v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined s4 splicing region required to bind necessary binding region required to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined extracellular region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 29 unspecified role unspecified role neutral component neutral component region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined colocalization colocalization Binding of HA-Cbln1 to HEK293T cells transfected with NRXN1β-V5 but not to those transfected with NRXN1β(�S4)-V5. Fig. 4A cbln1-nrxn2-1 1 37 unspecified role unspecified role neutral component neutral component region v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined s4 splicing region required to bind necessary binding region required to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 29 unspecified role unspecified role neutral component neutral component region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined colocalization colocalization GluRδ2 Interacts with β-NRXN in the Presence of Cbln1 Supp. Fig. 4 cbln1-nrxn3-1 1 29 unspecified role unspecified role neutral component neutral component region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 8 unspecified role unspecified role neutral component neutral component region Fc fusion fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined s4 splicing region required to bind necessary binding region required to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined colocalization colocalization Supp. Fig. 4 cbln1-nrxn1-2 3 20 unspecified role unspecified role bait bait c-terminal alk phosphatase tag alkaline phosphatase tag alk phosphatase tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range c-terminal myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range extracellular region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined c-terminal his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. 29 unspecified role unspecified role prey prey region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. association association Pulldown assay of the interaction between NRXN1β-ECD-AMH and HA-Cbln1. Fig. 4B cbln1-nrxn1-3 2 20 unspecified role unspecified role bait bait c-terminal alk phosphatase tag alkaline phosphatase tag alk phosphatase tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range c-terminal myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range extracellular region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined c-terminal his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. 29 unspecified role unspecified role prey prey region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. association association Interaction kinetics was measured by passing various concentrations (0.625, 1.25, 2.5, 5, and 10 μg/ml) of purified HA-Cbln1-His over NRXN1β-ECD-Fc captured on the surface of a sensor chip. Fig. 4C pH 7.4, Temp=25C