IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Distinct factors control histone variant H3.3 localization at specific genomic regions. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (0092-8674) 2010 imex curation Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu 25-Jun-2010: Contacted by JYOTI. orchard Only protein-protein interactions mouse-neuronal_precursor_cells(stem cells) Mouse Neuronal precursor cells/neural stem progenitor cells neuronal_precursor (stem cells) Neuronal Precursor Cells/neural stem progenitor cells ch-ip chromatin immunoprecipitation assay ch-ip nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Accepted 2010-JUN-20 by ORCHARD. 25-Jun-2010: Contacted by JYOTI. Cell (0092-8674) 2010 orchard Only protein-protein interactions imex curation Distinct factors control histone variant H3.3 localization at specific genomic regions. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (0092-8674) 2010 imex curation Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu 25-Jun-2010: Contacted by JYOTI. orchard Only protein-protein interactions mouse-embryonic_stem cell Mus musculus embryonic stem cell es cells embryonic stem cells pull down pull down sequence tag sequence tag identification sequence tag Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Accepted 2010-JUN-20 by ORCHARD. Cell (0092-8674) 2010 orchard Only protein-protein interactions imex curation Distinct factors control histone variant H3.3 localization at specific genomic regions. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (0092-8674) 2010 imex curation Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu 25-Jun-2010: Contacted by JYOTI. orchard Only protein-protein interactions mouse-embryonic_stem cell Mus musculus embryonic stem cell es cells embryonic stem cells ch-ip chromatin immunoprecipitation assay ch-ip nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". Some interactions are missing due to the use of non-specific anti-H3 antibodies. The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Accepted 2010-JUN-20 by ORCHARD. 25-Jun-2010: Contacted by JYOTI. Cell (0092-8674) 2010 orchard Only protein-protein interactions imex curation Distinct factors control histone variant H3.3 localization at specific genomic regions. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (0092-8674) 2010 imex curation Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu 25-Jun-2010: Contacted by JYOTI. orchard Only protein-protein interactions human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 pull down pull down western blot western blot Immuno blot Immuno blot Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Accepted 2010-JUN-20 by ORCHARD. 25-Jun-2010: Contacted by JYOTI. Cell (0092-8674) 2010 orchard Only protein-protein interactions imex curation Distinct factors control histone variant H3.3 localization at specific genomic regions. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (0092-8674) 2010 imex curation Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu 25-Jun-2010: Contacted by JYOTI. orchard Only protein-protein interactions mouse-embryonic_stem cell Mus musculus embryonic stem cell es cells embryonic stem cells confocal microscopy confocal microscopy tag fluorescence tag visualisation by fluorescence tag fluorescence Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Accepted 2010-JUN-20 by ORCHARD. 25-Jun-2010: Contacted by JYOTI. Cell (0092-8674) 2010 orchard Only protein-protein interactions imex curation Distinct factors control histone variant H3.3 localization at specific genomic regions. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (0092-8674) 2010 imex curation Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu 25-Jun-2010: Contacted by JYOTI. orchard Only protein-protein interactions mouse-embryonic_stem cell Mus musculus embryonic stem cell es cells embryonic stem cells ch-ip chromatin immunoprecipitation assay ch-ip predetermined predetermined participant predetermined Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Accepted 2010-JUN-20 by ORCHARD. 25-Jun-2010: Contacted by JYOTI. Cell (0092-8674) 2010 orchard Only protein-protein interactions imex curation Distinct factors control histone variant H3.3 localization at specific genomic regions. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (0092-8674) 2010 imex curation Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu 25-Jun-2010: Contacted by JYOTI. orchard Only protein-protein interactions mouse-embryonic_stem cell Mus musculus embryonic stem cell es cells embryonic stem cells anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". Fig 6A/B is Immunoprecipitation, according to text and image legend for Image S6 A/B - but not, of course, in the relevant image legend for Fig 6B. I am assuming that IP antibodies were used to H3.3 etc... as given across the top of the columns, and WB down the side. Similarly, the text (further down) states that Figs 6C is "immunoblot" -6E is a "pull -down". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Accepted 2010-JUN-20 by ORCHARD. 25-Jun-2010: Contacted by JYOTI. Cell (0092-8674) 2010 orchard Only protein-protein interactions imex curation q3v122_mouse DNA replication licensing factor MCM7 Mcm7 MCM7 protein protein mouse Mus musculus Mouse MALKDYAIEKEKVKKFLQEFYYENELGKKQFKYGTQLVHLAHREQVALYVDLDDIAEDDPELVDSICENAKRYSRLFGDVVQELLPEYKEKEVVNKDVLDVYIEHRLMMEQRSRDPGAVRNPQNQYPSELMRRFELYFRGPSSSKPRVIREVRADSVGKLLTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFVKFQEMKIQEHSDQVPVGNIPRSITVVLEGENTRIAQPGDHVSVTGIFLPVLRTGFQQMAQGLLSETYLEAHWIVKMTKSDDDVSGAGELSSEELKQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLLVGGVDQSPQGMKIRGNIHICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNVQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPAQFEPLDMKLMRRYIAMCHERQPTVPESLADYITAAYVEMRREARASKDATYTSARTLLAILRLSTALARLRMVDIVEKEDVNEAIRLMEMSKDSLLGEKGQTARTQRPADVIFATIRELVSRGRSVHFSEAEQRCISRGFTPAQFQAALDEYEELNVWQVNTSRTRITFV 2829CEEC115713BD dhx9_mouse ATP-dependent RNA helicase A Dhx9 Ddx9 Nuclear DNA helicase II DEAH box protein 9 RNA helicase A protein protein mouse Mus musculus Mouse MGDIKNFLYAWCGKRKMTPAYEIRAVGNKNRQKFMCEVRVEGFNYAGMGNSTNKKDAQSNAARDFVNYLVRINEVKSEEVPAVGIVPPPPILSDTSDSTASAAEGLPAPMGGPLPPHLALKAEENNSGVESSGYGSPGPTWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLENAKARLNQYFQKEKIQGEYKYTQVGPDHNRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQSCALSLVRQLYHLGVIEAYSGLTKKKEGERVEPYKVFLSPDLELQLQNVVQELDLEIVPPPVDPSMPVILNIGKLAHFEPSQRQNAVGVVPWSPPQSNWNPWTSSNIDEGPLAYASTEQISMDLKNELTYQMEQDHNLQSVLQERELLPVKKFEAEILEAISSNSVVIIRGATGCGKTTQVPQYILDDFIQNDRAAECNIVVTQPRRISAVAVAERVAYERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVLAYPEVRIVLMSATIDTTMFCEYFFNCPIIEVYGRTFPVQEYFLEDCIQMTQFIPPPKDKKKKDKEDDGGEDDDANCNLICGDEYGPETKLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLENNSHFGSHRYQILPLHSQIPREEQRKVFDPVPDGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFDRLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAIIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAVCTISAATCFPEPFISEGKRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMSGEEAEIRFCEQKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQIVFIDDWIRLQISHEAAACITIRAAMEALVVEVSKQPNIISQLDPVNEHMLNTIRQISRPSAAGINLMIGSVRYGDGPRPPKMARYDNGSGYRRGYGGGGYGGGGYGGGYGSGGFGGGFGSGGGFGGGFNSGGGGFGSGGGGFGSGGGGFGGGGGGFSGGGGGGFGGGRGGGGGGFGGSGGFGNGGGGYGVGGGGYGGGGGGGYGGGSGGYGGGGYGGGEGYSISPNSYRGNYGGGGGGYRGGSQGGYRNNFGGDYRGSSGDYRGSGGGYRGSGGFQRRGYGGGYFGQGRGGGGGGGY 005D641CD9A4F0C9 ubiq_mouse Ubiquitin Rps27a Uba80 Ubcep1 Uba52 Ubcep2 Ubb Ubc protein protein mouse Mus musculus Mouse MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG C42A35397FFD9B52 q8cgp4_mouse Histone H2A H2ac1 Hist1h2aa protein protein mouse Mus musculus Mouse MSGPTKRGGKARAKVKSRSSRAGLQFPVGRVHRLLRQGNYAQRIGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKTRITPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHKSQTK 8F9E3AA0792CE4A6 rpb1_mouse DNA-directed RNA polymerase II subunit RPB1 Polr2a Rpii215 Rpo2-1 DNA-directed RNA polymerase II subunit A DNA-directed RNA polymerase III largest subunit protein protein mouse Mus musculus Mouse MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPASPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN DIP protein P08775 original sequence version: 94 DIP protein P08775 original sequence version: 114 DIP protein P08775 original sequence version: 110 DIP protein P08775 original sequence version: 123 7D76F38FD92A657E h2az_mouse Histone H2A.Z H2az1 H2afz H2az protein protein mouse Mus musculus Mouse MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV E024E53818230371 q3uj03_mouse Poly [ADP-ribose] polymerase Parp1 protein protein mouse Mus musculus Mouse MAEASERLYRVEYAKSGRASCKKCSESIPKDSLRMTIMVQSPMFDGKVPHWYHFSCFWKVGHSIRQPDVEVDGFSELRWDDQQKVKKTAEAGGVAGKGQDGSGGKAEKTLGDFLAEYAKSNRSMCKGCLEKIEKGQMRLSKKMVDPEKPQLGMIDRWYHPTCFVKKRDELGFRPEYSASQLKGFSLLSAEDKEALKKQLPAIKNEGKRKGDEVDGTDEVAKKKSKKGKDKDSSKLEKALKAQNELIWNIKDELKKACSTNDLKELLIFNQQQVPSGESAILDRVADGMAFGALLPCKECSGQLVFKSDAYYCTGDVTAWTKCMVKTQNPSRKEWVTPKGFREISYLKKLKVKKQDRIFPPESSAPAPLALPLSVTSAPTAVNSSAPADKPLSNMKILTLGKLSQNKDEAKAVIEKLGGKLTGSANKASLCISTKKEVEKMSKKMEEVKAANVRVVCEDFLQDVSASTKSLQELLSAHSLSSWGAEVKAEPGEVVAPKGKSAAPSKKSKGAVKEEGVNKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVRGTNSYYKLQLLEDDKESRYWIFRSWGRVGTVIGSNKLEQMPSKEDAVEHFMELYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVKPGTKSKLPKPVQELVGMIFDVESMKKALVEYEIDLQKMPLGKLSRRQIQAAYSILSEVQQAVSQGSSESQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVIDIFKIEREGESQRYKPFRQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSASITLEGVEVPLGTGIPSGVNDTCLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW BF83A64B8879C37A ldha_mouse_gene Mouse L-lactate dehydrogenase A chain gene gene gene mouse Mus musculus Mouse h32_mouse Histone H3.2 H3c13 H3c14 H3c15 H3c2 H3c3 H3c4 H3c6 H3c7 H3-143 H3-53 H3-B H3-F H3-clustered histone 13 H3-clustered histone 14 H3-clustered histone 15 H3-clustered histone 2 H3-clustered histone 3 H3-clustered histone 4 H3-clustered histone 6 H3-clustered histone 7 H3.2 H3.2-221 H3.2-614 H3.2-615 H3.2-616 H3b H3f Hist1h3b Hist1h3c Hist1h3d Hist1h3e Hist1h3f Hist2h3b Hist2h3c1 Hist2h3c2 Hist2h3ca1 Hist2h3ca2 protein protein mouse Mus musculus Mouse MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA DIP protein P84228 original sequence version: 65 6FD8508EA50A0EEC nanog_mouse_gene gene gene mouse Mus musculus Mouse fog2_mouse_gene Mouse ZFPM2 gene gene gene mouse Mus musculus Mouse daxx_human Death domain-associated protein 6 DAXX BING2 DAP6 Daxx Fas death domain-associated protein ETS1-associated protein 1 protein protein human Homo sapiens Human MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYKLENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRPAKLYVYINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPRTRGSRRQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARHSLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKICTLPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTCKTSVATQCDPEEIIVLSDSD 1B309ADDAA878040 dnjc9_mouse DnaJ homolog subfamily C member 9 Dnajc9 protein protein mouse Mus musculus Mouse MGLLELCEQVFGTADLYQVLGVRREASDGEVRRGYHKVSLQVHPDRVEEDQKEDATRRFQILGRVYAVLSDKEQKAVYDEQGTVDEDSAGLNQDRDWDAYWRLLFKKISLEDIQAFEKTYKGSEEELNDIKQAYLDFKGDMDQIMESVLCVQYTDEPRIRNIIQKAIESKEIPAYSAFVKESKQKMNARKRRAQEEAKEAELSRKELGLEEGVDNLKALIQSRQKDRQKEMDSFLAQMEAKYCKPSKGGKRTALKKEKK ED959F4CC5B94343 h33_mouse Histone H3.3 H3-3a H3-3b H3.3a H3.3b H3f3a H3f3b protein protein mouse Mus musculus Mouse MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA DIP protein P84244 original sequence version: 112 5158ED279E6F9E1C sp16h_mouse FACT complex subunit SPT16 Supt16h Fact140 Factp140 Facilitates chromatin transcription complex subunit SPT16 FACT 140 kDa subunit FACTp140 Chromatin-specific transcription elongation factor 140 kDa subunit Supt16 protein protein mouse Mus musculus Mouse MAVTLDKDAYYRRVKRLYSNWRKGEDEYASIDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLVREKNESNKSSFDKMIDAIKESKSGKKIGVFSKDKFPGEFMKSWSDCLNKEGFDKVDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPTQEVQENYNFLLQLQEELLKELRHGVKICDVYNSVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATILTSVKKKVKNVGIFLKNEDDEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAVMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEDGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK DIP protein Q920B9 original sequence version: 69 51931F5639CD221E atpb_mouse ATP synthase subunit beta, mitochondrial Atp5f1b ATP synthase F1 subunit beta Atp5b protein protein mouse Mus musculus Mouse MLSLVGRVASASASGALRGLSPSAALPQAQLLLRAAPAGVHPARDYAAQASAAPKAGTATGRIVAVIGAVVDVQFDEGLPPILNALEVQGRDSRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFIEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGNEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEHGS F3E1100C390A78A7 q9dae2_mouse Rbmxl2 protein protein mouse Mus musculus Mouse MVEADRPGKLFIGGLNLETDEKGLETAFGKYGRIIEVLLMKDRETSKSRGFAFVTFENPADAKAAARDMNGKSLDGKAIKVAQATKPVFESGRRGPPPPRSRGRPRGLRGTRGGGPRRPPSRGGSADEGGYTGDFDLRPSRAPMPLKRGPPPRRAGPPPKRAAPSGPARSGAGIRGRAAGSRGRDGYGGPPRRELPPPRRDPYLGPRDEGYSPRESYSSRDYPSARDPRDFAPSPRDYTYRDYGHSSARDECPSRGYCERDGYGGRERDYEHPSGGSYRDPFDSYGDPRGAGPARGPPPSYGGGRYDEYRGCSPDGYGGRDSYRSERYSSGRERVGRPERGLPPSVERNCPAPRDSYSRSGRRAPPRGGGRVGSRLERGGGRSRY C16FA2F6F98B64DD q68fn3_mouse Ubr7 protein protein mouse Mus musculus Mouse GSHKLFELYTKRNFRCDCGNSKFKNLECKLFPDKSKVNSCNKYNDNFFGLYCVCKRPYPDPEDEVPDEMIQCVVCEDWFHGRHLGAIPPESGDFQEMVCQACMRRCSFLWAYAAQLAVTRISAEDDGLLPNATGMGDEDVSKPENGAPQDNGLKEDAPEHGRDSVNEVKAEQKNEPCSSSSSESDLQTVFKKENIKTEPQSSCRLQELQAKQFVKKDAATYWPLNWRSKLCTCQDCMKMYGELDVLFLTDECDTVLAYENKGKNDQATDRRDPLMDTLSSMNRVQQVELICEYNDLKTELKDYLKRFADEGTVVKREDIQQFFEEFQSKKRRRVDGLQYYCS A387811891A12132 hat1_mouse Histone acetyltransferase type B catalytic subunit Hat1 Histone acetyltransferase 1 protein protein mouse Mus musculus Mouse MAALEKFLVEYKSAVEKKLAEYKCNTNTAIELKLVRFPEDLENDIRTFFPEYTHQLFGDDETAFGYKGLKILLYYIAGSLSTLFRVEYSSKVDENFDCVEADDVEGKIRQIIPPGFCTNTNDFLSLLEKETNFKPFGTLLHTYTVPSQTGGETFTFQIHKADMTCRGFREYHERLQTFLMWFIETASFIDVDDERWHYFLVFEKYNKDGATLFATVGYMTVYNYYVYPDKTRPRVSQMLILTPFQGQGHGAQLLETVHRYYISFPTVLDITAEDPSRSYLKLRDFVLVKFCQFLPSFSRERLLQGFSEDMAIQAQQMFKINKQHARRVYEILRLLVTDMSDAEQYRSYRLDIKRRLISPYKKKQRDLAKMKKCLRPEELTNQMNQIEISVQHEQLEERFQELVEDYRRVIERLAQE A20D53ABF1A7C824 h31_mouse Histone H3.1 H3c1 H3c10 H3c11 H3c8 H3.1-221 H3.1-291 H3.1-I H3a H3g H3h H3i Hist1h3a Hist1h3g Hist1h3h Hist1h3i protein protein mouse Mus musculus Mouse MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 9B89008EA50A0EF6 gas5_mouse_gene Mouse Non coding RNA Gas5 gene gene gene mouse Mus musculus Mouse atrx_mouse Transcriptional regulator ATRX Xnp ATP-dependent helicase ATRX HP1 alpha-interacting protein HP1-BP38 protein Heterochromatin protein 2 X-linked nuclear protein Atrx Hp1bp2 protein protein mouse Mus musculus Mouse MTAEPMSGNKLSTLVQKLHDFLAHSSEESEETCSSPRLVMNQSTDKICGSGLNSDMMENNKEEGASTSEKSRSSGSSRSKRKPSIVTKYVESDDEKPTDENVNEKAATENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKADNLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLKVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICQPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKTSKVCDQTSKFSPKKSSSSCNGEEKKLEESCSGSVSSTYSHSALSVPKEMIKKTTKLIETTSNMNSSYIKFLKQAADNSEMTSAMKLCQLKSFKSVLDDIKKAHLALEEDLNSEIQALDDVHKEKNTKDLKSTDAKSETKLGKGEKSYSTEKREFLKLDARSSVKAIDGEEQRAHKSTSGEHKGSGRKDGSQYEPTNTPEDLDMDIVSVPSSVPEDIFDSLESAMEVQSSADYQGDGNSGTEPELESSSVKLNVSSKDSRGNIKSKVTAKVRKELFVKLTPVSLSNSPIKGVDCQEVSQEKNGRKSSGVARSSEKCRPREEISDHENNVTILLEDSDLRRSPRVKTTPLRRQTESNPAMSNSDEESNGTMKEKQKMSGPIRKKDKRNSADCATDNPKPHKVPKAKQPVIGDQNSDSDEMLAVLKEASQMGHSSSSDTDINEPQMNHKGKTGKDDNGKRKRKNSTSGSDFDTKKGKSTETSIISKKKRQNYSESSNYDSELEREIKTMSRIGAARKSVPEKKEEDSSEDEKQGKKVVDNGGHERAKTTQEGSSADDTGDTEGRQGGSCSIAGGSIEKVRSGVEFREMLCKPGVSSDGAEKPSVKEENVNSPEDKRVSKTKEKTKHLRSRQSRKGKGGSSDGTDRFPKKEQSDESSEGEKKQSRQRPGTKGKKAPDLKGETLKREQEWDSSSDGTERLPEEEEIGPFSKGIKQSKTDTAGGEKKGKKWKDKSCEKKEELSDSVDKLPGKGDSCDSSEDKKTRNRVSLREKKRFSLPAKSPGKRPECSSSDTEKSLKGQCCDSTEKRPKRIDLRERRNSSSKRNTKEVKSASSSSDAEGSSEDNKKQKKQRTSAKKKTGNTKEKKRNSLRATPKRKQVDITSSSSDIGDDDQNSAGEESSDEQKIKPVTENLVLPSHTGFCQSSGDEALSKSVPATVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPDGGGKKRIGKQSEESPADDGELRREQLAVNQVNSESDSDSEESKKPRYRHRLLRHKLTLSDGESGEEKPTKPKEHKEAKGRNRRKVSSEDSEDTDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSHSEEDKKEGDEEDEEDEDEDEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDENEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVEKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLNDNEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKDIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIKSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTAIQCKLYQYYLDHLTGVGNSTEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSKSLSSDEKKKPKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGDGNVDDTGNNPSVSLKLDESKTTSTSNPSSPAPDWYKDFVTDTDAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKEKPLIYKGEGKWIRNIDYYRLDGSTNAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVTFTSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSMTAVRIQPLEDIISTVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLINCVQRILMNRRLQQQYTQQQQQQLTYQQATLSHLMMPKPPNLIMTPSNYQQIDMRGMYQSVAGGMQPPPLQRAPPPTVRSKNPGPSPGKSM DIP protein Q61687 original sequence version: 129 DIP protein Q61687 original sequence version: 140 B2E2218B6CC791EC dnm3a_mouse DNA (cytosine-5)-methyltransferase 3A DNA methyltransferase MmuIIIA Cysteine methyltransferase DNMT3A Dnmt3a protein protein mouse Mus musculus Mouse MPSSGPGDTSSSSLEREDDRKEGEEQEENRGKEERQEPSATARKVGRPGRKRKHPPVESSDTPKDPAVTTKSQPMAQDSGPSDLLPNGDLEKRSEPQPEEGSPAAGQKGGAPAEGEGTETPPEASRAVENGCCVTKEGRGASAGEGKEQKQTNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAVMNAVEENQASGESQKVEEASPPAVQQPTDPASPTVATTPEPVGGDAGDKNATKAADDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPACHDSDESDSGKAVEVQNKQMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTTEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFIGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV 5F98D5A8092C84A5 asf1a_mouse Histone chaperone ASF1A Asf1a Anti-silencing function protein 1 homolog A protein protein mouse Mus musculus Mouse MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAESEEYDQVLDSVLVGPVPAGRHMFVFQADAPNAGLIPDADAVGVTVVLITCTYRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFHINWEDNTEKLEDAESSNPNLQSLLSTDALPSASKGWSTSENSLNVMLESHMDCM 9803653A63B8FC68 q3uji2_mouse CAF1C_H4-bd domain-containing protein Rbbp7 protein protein mouse Mus musculus Mouse MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDSRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTASELEGQGS FA49AF5C70620313 macf1_mouse Microtubule-actin cross-linking factor 1 Actin cross-linking family 7 Macf1 Acf7 Aclp7 Macf protein protein mouse Mus musculus Mouse MSSSDEETLSERSCRSERSCRSERSYRSERSGSLSPCPPGDTLPWNLPLHEQKKRKSQDSVLDPAERAVVRVADERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGVKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQVQSNRENLEQAFEVAERLGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEGGEGISATEVDSRWQEYQSRVDSLIPWIRQHTILMSDKSFPQNPVELKALYNQYIHFKETEILAKEREKGRIKELYKLLEVWIEFGRIKLPQGYHPNHVEEEWGKLIVEMLEREKSLRPAVERLELLLQIANKIQNGALNCEEKLTLAKNTLQADAAHLESGQPVQCESDVIMYIQECEGLIRQLQVDLQILRDEKYYQLEELAFRVMRLQDELVTLRLECTNLYRKGHFSSLELVPPSTLTTTHLKAEPLNKTTHSSSTSWFRKPMTRTELVSISSSEDEGNLRFVYELLSWVEEMQMKLERAEWGNDLPSVELQLETQQHIHTSVEELGSSVKEARLYEGKMSQNFHTSYVETLGKLETQYCKLKETSSFRMRHLQSLHKFVSRATAELIWLNGKEEEELACDWSDSNPNISAKKTYFSELTMELEGKQDVFRSLQDTAEVLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHVKENAAYFQFFSDARDLESFLRNLQDSIKRKYTCDRSTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIVQLKPRNPDHVLKSTLSVKAICDYRQIEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNKEAIEMASRVEQSYQKVMALWHQLHINTKSLISWNYLRKDLDTVQTWSLEKLRSLAPGECHQVMKNLQAHYEDFLQDSHDSALFSVADRLRIEEEVEACKAHFQHLMKSLENEDKEETLAKVYISELKNIRLLLEECEQRLLKQIQSPASSKTDRDARQDITLRIAEQEHTQEDLQHLRSDLDAISMKCNVFLQQSPSGSSATTLRSELNLMVEKMDHVYGLSTVYLNKLKTIDVIVRSMQDAELLVKGYEIKLSQEEAVPADLSALESHRTTLQHWLSDVKDKNSVFSVLDEEITKAKKVAEQLRHPASEPNLDLERYQEKGSQLQERWHRVIAQLETRQSEVESIQEVLRDYRACHGTLIKWIEETTAQQEMMKPGQAEDSRVLSEQLSQQTELFAEIERNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAFVESQQKSPGKRRRMISSSDAITQEFMDLRTRYTALVTLTTQHVKYISDALRRLEEEEKVVEEEKQEHVEKVKDLLGWVSTLARNTQGTTTSSHTSASADIEKAILEQQVLAEELTTKKEQVSEAIKTSQIFLAKHGHKLSEGEKEQISEQLRVLNKTYHDLCDGSANQLQQLQSELAQQTEQKGCRAVAGVIDLGTVEIFPIFRAMQKGLIDQDTGLVLLESQIIMSGLIDPENSEKLSLEEGLTRNFINLPIYQQLLGLRDSLSLVSRLTGTLGSLSVVEAIEKKIISERLGLKVLEVHLATGGFSLPPSENCINLEEAFHQGFIASSLHSELQSHLRSSKNLIDPNTAEKVGLLDLMQRCIIHQESGLKLLPVKQLAGGMVSLKSGRKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGDRMTIDEAVTNNLVAAKIALVILESLWSFMGLLLPESGEILPITDALEQGIVSTELAHKILHNRQQIEALFLPTLTEIWSWEKATESGILDKDLVNNLRSVCIPDMMPHIQLADSAEQSKVGFAAGKPPVSGPREEGSSHGEKLLFQLMTHSYIHAHTGQRLLLLDQELVEMLTSRDDCQVILPEVFEIQHQRLNTSEALQELYTGTISQISSAKHPRKPCESQFLSQNKDYPSQENCTEAKGERSVVGIECSPAESPERELFLKEQEAIIENVGSLKVINKVKLKLQRPLLGSRKEEQAETLREENISGDPLLVECPEESEGKDLSTEKSKCQTPTKCSFTCHKEQVKTIKDIPSETGTSLIKSQNQMSQFQVDTSVGLRSEFKSEHDMNVNSLEKELKEELLVKDGHKQSQEGQSVADGQTVALEKTDTEDNADEPALLHSSPFEDATLSTLSAQLQDGGIFNEETGQKLLLNEAIAQGLVSSHTAVKLMGKLNMFRGFFDSQTCESLTTEEVIDEGLMDEKLLYNVLMSDKAISGILDPRTHSLCSVKEAVAAGLLDKETATRILEGQVITGGIVDLKRGKKLSVTLASNLGLVDTADQTELINLEKATKGRGAEKAVKERLIELQMETAGLMDPESKAPLTVLQSIDRGILEREAAVYLLTKQVLDGGIIHHISGLRLSVDNAFKHGLIGEDMARQLRKVENFIHYQFFHPQTKEALSFSEAIKLDLVSPDLKREIQEIQDFSGNLGDFIYGQKLTLAKTNKEESLANKTELPSGVMHGVIDPENCTIIPYSELVKKCRIDTESGWRYLEVIPFSDIKDEAGNNVLTPPEAIQLGKVDFASALKVLEAQANTGGIIDMATGKRVTLASALEKKLLDENMARIIASHQMLSGGIIDIYSDQRVTLNDAVEKRLISPELAAMIQVDPLAEQGGTGVCELKGDFLRKELLSESSKTPRESYSKEKHEAVLQAGSLCAPEKAGIRGSNGEKAEKGRKISVEMEGQRQDEKASSDSKVSASILSPFGFEGESSYQVSVTHPCSESCDLKPREETRSCMKKCAVVERDKVVTQIKMVSHVKQSTSGLDAEEARERQGRMVSKEQGSHYETAGNLLSERSVRVDRRVRREMGGEQSVQMSREAAVLSEEESDQEVTIGDEPDSFVKSQSMKMIGNDKGKEAGIEKDISVVCKIEGFPSQMTSKDASLTNQDALPFYTEGETKTVNLCSILKPGEKLSQETASTVQKEPLSSEIPRPERLNSQESDEEPQISDVPHISKGDMAAQITTRQETTDVQDLYITSKSSETKDKIFPSKNYIEKLHQEIPMDPTRSHKLKEATISTLETEGISYLDSSDIKSLCEDSKADHKSCGHQKSKVTTTQAKKSLEVVDLLVRDTEEGSSEDRVGQRGPRVLASLLPEKLPTRTVQSENIRQHDAVIPAISEIREEMALSLPCSVVKVDGKIPKEKHKEILGDEQGPFMAIPSGKGIEGVNPEPCRATQNVFTRRLCLEHDEKLVSYLSLLRDIEMRTKQIQPLELNVAELQDLLGQAKELDRELKDLSTVVSQELECVDRIVISQPQEVPAQLLKALEKDAKNLQKSLDSVSDSWSSRFLHLQSAVEVKKATVLNRHKELQGKLQDLRAWVGRASLTLNSKGCDTETDADSLSHTLQPYKDMKQSMAERKSQLDALALDIQLFISEHPQDLSLQQNQEMLQFLSELQRSFQGLVEHTAAQKDVVQGHLQQVQQEVQVKTLQKQQDTCHKKLEDLCNWVGQAERALERHQGGSSSGKSSLLCAEPKVDLKDLQGDIQSHSTSFATAVKDIEGFLEENQTKLSPQELTALREKLHQAKEQYEVLQERTRVAQKELEEAVTSALQQETEKSKAATELAENKRKIDALLDWVGLLWGHLRESHRLAFQEWSSSLELAMEKQTLAATDGHVDVNQVPETLDRQYELMKARHQELLSQQQNFIVATQSVQSFLDQHSHNLTPEERQKLQEKLGELKEQYAASLARSEAELKQTQALRDELQKFLQDHKEFENWLQQSENELDSMHKGGSSPEALNSLLKRQGSFSEDVISHKGDLRFVTISGQKVLETENNFEEGQEPSATRNLVNEKLKDATERYTTLHSKCIRLGSHLSMLLGQYQQFQSSADSLQAWVLTCEASVGKLLSDTVASDPGVLQQQLATTKQLQEELAEHQVPVEKLQKAAHDLLDIEGEPALDCRPIQETTDSISSRFQNLSCSLDERSALLQKAIAQSQSVQESMESLLQSIREVEQNLERDQVASLSSGVIQEALANNMKLKQDIARQKSSLEATHDMVTRFMETADSNSASVLQGKLAELSQRFQQLQLQQQEKESNLKKLLPQAEMFEQLSNKLQQFMENKSRLLASGNQPDQDIAHFSQQIQELTLAMEDQKENLDTLEHLVTTLGSCGFALDLSQHQDKIQNLKKDFTELQKTVQEREKDASTCQEQLDEFRKLIRTFQKWLKETEGNVPPAKTFVSAKELEKQIEHLKDLISDWESKGALLGEINAKGTALESLIMDITAPDSQAKTGSILPPVGSSVGSVNGYHTCKDLTEIQCDMFDVNSKYEKLWEVLRERQESLQTVFSRMEEVQKEASSVLQWLESKEEVLKAMDATLSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLKTYPNSQEAENWKKMQEDLNSRWEKATEVTVARQKQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLSIDPNMLKQQVQFMLKEFEARRQQHEQLNEAAQGILTGPGDMSPSASQVHKDLQSISQKWVELTDKLNSRSSQIDQAIVKSTQYQDLLQDLSEKVKAIGQRLSGQSAISTQPEAVKQQLEETSEIRSDLGQLDNEIKEAQTLCQELSLLIGEQYLKDELKKRLETVALPLQGLEDLAADRMNRLQAALASTQQFQQMFDELRTWLDEKQSQQAKNCPISAKLERLQCQLQENEEFQKNLNQHSGSYEVIVAEGEALLLSVPPGEEKKTLQNQLVELRSHWEDLSKKTANRQSRLKDCMQKAQKYQGHVEDLVPWIDECKSKMSELQVTLDPVQLESSLLRSKAMLNEAEKRRSLLEILNSAADILINSSEIDEDEIRDEKAGLNQNMDAITEELQAKTSSLEEMTQRLKEFQESFKNIEKKVEGAKHQLEIFDALGSQACSNKNLEKLKAQQEVLQALEPQVDYLRNFTQGLVEDAPDGSDASPLVHQAEVAQQEFLEVKQRVSSSCLTMENKLEGIGQFHCRVREMFSQLADLDDELDGMGAIGRDTDSLQSQIEDVRLFLNKIQALRFDIEDSEAECRKMLEEEGTLDLLGLKRELEALNKQCGKLTERGKVRQEQLELTLGRVEDFYRKLKALNDAATAAEEGEALQWIVGTEVDVINQQLADFKLFQKDQVDPLQVKLQQVNGLGQGLIQSAGKNCDVQGLEHDMDEINTRWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLTDTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLERRWTDLLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTANKLANSEPVGTQTAKIHQQIIRHKALNEEIINRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITLTSSKALRTLEQARQLATKFHSTYEELTGWLREAEEELAASGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSHALLELVPWRAREGLDKLVSDANEQYKLISDTVGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRGEIFSTCGEEQKAVLQEKTECLIQQYEAVSLLNSERYARLERAQVLVNQFWETYEELSPWAEETLALIAQLPPPAVDHEQLRQQQEEMRQLRESIAEHKPHIDKILKIGPQLKELNPEEGKMVEEKYQKAENMYAQIKDEVRQRALALDEAVSQSAQFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARSEEREIKFLDVLELAEKFWYDMAALLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVKKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVATVNKAGSELLESSAGDDASSLRSRLETMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELNRMENQLSASKPTGGLPETAREQLDTHMELHSQLRAKEEIYNQLLDKGRLMLLSRGDSGSGSKTEQSVALLEQKWHAVSSKVEERKSKLEEALSLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNDHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLAGDTQKLDNLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIEGSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEEFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNTAVAMGEAILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALITEHQSFMEEMTRKQPDVDRVTKTYKRKSVEPTHAPFMEKSRSGSRKSLNQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELCPELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVISSSGSKLKRPTPAFHSSRTSLAGDTSNSSSPASTGAKANRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGSSRRGLTKPSKIPTMSKKTTTASPRTPGPKR 2B68195989DE15C7 gtr3_mouse_gene Mouse SLC2A3 solute carrier type 2 gene gene gene mouse Mus musculus Mouse err2_mouse_gene Mouse esrrb gene gene gene mouse Mus musculus Mouse asf1b_mouse Histone chaperone ASF1B Asf1b Anti-silencing function protein 1 homolog B protein protein mouse Mus musculus Mouse MAKVSVLNVAVLENPSPFHSPFRFEISFECSEALSDDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQADAPNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVNNEYPDPELRENPPPKPDFSQLQRNILASNPRVTRFHINWDNNPDSLEAIENQDPNVDFSLSLSCTPVKSLGLPSCIPGLLPENSMDCI A02546180DA18A48 pparg_mouse_gene Mouse Peroxisome proliferator-activated receptor gamma gene gene gene mouse Mus musculus Mouse atrx_human Transcriptional regulator ATRX ATRX RAD54L XH2 ATP-dependent helicase ATRX X-linked helicase II X-linked nuclear protein Znf-HX protein protein human Homo sapiens Human MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM 637E341F6A4B29C6 smca5_mouse SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 Smarca5 Snf2h Sucrose nonfermenting protein 2 homolog protein protein mouse Mus musculus Mouse MSSAVEPPPPPPPESAPSKPSAAGAGGSSSGNKGGPEGGAAPAAPCAAGSGPADTEMEEVFDHGSPGKQKEIQEPDPTYEEKMQTDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRVKKDEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKKWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQKLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKDEMLQMIRHGATHVFASKESEITDEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDTESSVYNFEGEDYREKQKIAFTEWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRSPDLPNAAQAQKEEQLKIDEAEPLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEGKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYGTNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIERENMELEEKEKAEKKKRGPKPSTQKRKMDGAPDGRGRKKKLKL DIP protein Q91ZW3 original sequence version: 84 DIP protein Q91ZW3 original sequence version: 86 C6CB69E7FADE73FC ssrp1_mouse FACT complex subunit SSRP1 Ssrp1 Facilitates chromatin transcription complex subunit SSRP1 Structure-specific recognition protein 1 Recombination signal sequence recognition protein 1 T160 protein protein mouse Mus musculus Mouse MAETLEFNDIFQEVKGSMNDGRLRLSRQGIIFKNSKTGKVDNIQAGELTEGIWRRVALGHGLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDLCVKGWNWGTVKFGGQLLSFDIGDQPVFEIPLSNVSQCTTGKNEVTLEFHQNDDAEVSLMEVRFYVPPTQEDGVDPVEAFAQNVLSKADVIQATGDAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARGTTTTRSFDFEIETKQGTQYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGINPGYDDYADSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASASSSSNEGDSDREEKKREQLKRAKMAKDRKSRRKSSEAKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARREYEKAMKEYEGGRGDSSKRDKSKKKKKVKAKMEKKSTPSRGSSSKSSSRQLSDSFKSKEFVSSDESSSGENKSKKKRRRSEDSEEELASTPPSSEDSASGSDE 8259C1A6E9899843 hsp7c_mouse Heat shock cognate 71 kDa protein Heat shock 70 kDa protein 8 Hspa8 Hsc70 Hsc73 protein protein mouse Mus musculus Mouse MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD DIP protein P63017 original sequence version: 76 DIP protein P63017 original sequence version: 118 03A27B30E6C076ED telomeric_mouse_dna Mouse Telomere DNA probe dna deoxyribonucleic acid DNA deoxyribonucleic acid dna DNA deoxyribonucleic acid mouse Mus musculus Mouse TTAGGG 6878787DC1B1C000 b1au75_mouse Nuclear autoantigenic sperm protein Nasp protein protein mouse Mus musculus Mouse MATESTAAAAIAAELVSADKIEDAPAPSTSADKMESLDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNVDEEAREELREQVYDAMGEKEAKKAEGKSLTKPETDKEQESEVEKGGREDMDISEPEEKLQETVEPTSKQLTESSEEAKEAAIPGLNEDEVASGKTEQESLCTEKGKSISGAYVQNKEFRETVEEGEEIISLEKKPKETSEDQPIRAAEKQGTLMKVVEIEAEIDPQVKSADVGGEEPKDQVATSESELGKAVLMELSGQDVEASPVVAAEAGAEVSEKPGQEITVIPNNGPVVGQSTVGDQTPSEPQTSAERLTETKDGSSVEEVKAELVPEQEEAMLPVEESEAAGDGVETKVAQRATEKAPEDKFKIAANEETQERDEQMKEGEETEGSEEEDRENDKAEETPNESVLEKKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYIQAVEEFQACLSLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFGKSIDVIEKRMAVLHEQMKEAEGSFTEYEKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPSGAGASVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVSSGKEVSENMEAEAENQAESQTAEGTVESAATIKSTAC 7F0E6443700E87C2 mcm2_mouse DNA replication licensing factor MCM2 Minichromosome maintenance protein 2 homolog Nuclear protein BM28 Mcm2 Bm28 Cdcl1 Kiaa0030 Mcmd2 protein protein mouse Mus musculus Mouse MAESSESLSASSPARQRRRISDPLTSSPGRSSRRADALTSSPGRDLPPFEDESEGLLGTEGPMEEEEDGEELIGDGMERDYRPIPELDVYEAEGLALDDEDVEELTASQREAAERTMRQRDREAGRGLGRMRRGLLYDSSEEDEERPARKRRHVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCSKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEINMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATIILANHVAKKDNKVAVGELTDEDVKMITGLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVLCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKKDEGLTNGGTLEPAMPNTYGVEPLPQEVLKKYIIYAKERVRPKLNQMDQDKVARMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVMEDDVNMAIRVMMESFIDTQKFSVMRSMRKTFARYLSFRRDNNDLLLFILKQLVAEQVTYQRNRFGAQQDTIEIPEKDLMDKARQINIHNLSAFYDSDLFKFNKFSRDLKRKLILQQF DIP protein P97310 original sequence version: 77 7B61C13DAD1CAC58 daxx_mouse Death domain-associated protein 6 Daxx Daxx protein protein mouse Mus musculus Mouse MATDDSIIVLDDDDEDEAAAQPGPSNLPPNPASTGPGPGLSQQATGLSEPRVDGGSSNSGSRKCYKLDNEKLFEEFLELCKTETSDHPEVVPFLHKLQQRAQSVFLASAEFCNILSRVLARSRKRPAKIYVYINELCTVLKAHSIKKKLNLAPAASTTSEASGPNPPTEPPSDLTNTENTASEASRTRGSRRQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSSYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGLDTFPDYGDVLRAVEKAATRHSLGLPRQQLQLLAQDAFRDVGVRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPTLARRLRENRTLAMNRLDEVISKYAMMQDKTEEGERQKRRARLLGTAPQPSDPPQASSESGEGPSGMASQECPTTSKAETDDDDDDDDDDDEDNEESEEEEEEEEEEKEATEDEDEDLEQLQEDQGGDEEEEGGDNEGNESPTSPSDFFHRRNSEPAEGLRTPEGQQKRGLTETPASPPGASLDPPSTDAESSGEQLLEPLLGDESPVSQLAELEMEALPEERDISSPRKKSEDSLPTILENGAAVVTSTSVNGRVSSHTWRDASPPSKRFRKEKKQLGSGLLGNSYIKEPMAQQDSGQNTSVQPMPSPPLASVASVADSSTRVDSPSHELVTSSLCSPSPSLLLQTPQAQSLRQCIYKTSVATQCDPEEIIVLSDSD DIP protein O35613 original sequence version: 124 8407D5788528AC2D egfr_mouse_gene gene gene mouse Mus musculus Mouse rs19_mouse_gene Mouse 40S ribosomal protein S19 (RPS19) gene gene gene mouse Mus musculus Mouse h33_human Histone H3.3 H3-3A H3-3B H3.3A H3.3B H3F3 H3F3A H3F3B PP781 protein protein human Homo sapiens Human MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA DIP protein P84243 original sequence version: 72 DIP protein P84243 original sequence version: 73 DIP protein P84243 original sequence version: 97 DIP protein P84243 original sequence version: 125 DIP protein P84243 original sequence version: 110 DIP protein P84243 original sequence version: 96 5158ED279E6F9E1C actb_mouse_gene Mouse Beta ACTIN gene gene gene mouse Mus musculus Mouse mcm6_mouse DNA replication licensing factor MCM6 Mis5 homolog Mcm6 Mcmd6 Mis5 protein protein mouse Mus musculus Mouse MDLAAAAEPGAGSQHPEVRDEVAEKCQKLFLDFLEEFQGSDGEIKYLQFAEELIRPERNTLVVSFADLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPFAKDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIKDVEQQFKYTQPNICRNPVCANRKRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDRCDFTGALIVVPDVSKLSTPGARAETNSRVSGADGYETEGIRGLRALGVRDLSYRLVFLACHVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVDEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDMRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVSGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKRLRQRDGSGVTKSSWRITVRQLESMIRLSESMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMETDEGQGGVNGHADSPAPVNRFNGSSEDASQETVSKPSLRLGFAEYCRISNLIVLHLRKMEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKTIIEKVVHRLTHYDHVLIELTQAGLKGSSEGSESYEEDPYLVVNPNYLLED 79E753D2DA218CBF rgs9_mouse Regulator of G-protein signaling 9 Rgs9 protein protein mouse Mus musculus Mouse MTIRHQGQQYRPRMAFLQKIEALVKDMQNPETGVRMHNQRVLVTSVPHAMTGGDVLQWITQRLWISNLEAQNLGNFIVKYGYIYPLQDPKNLILKPDSSLYRFQTPYFWPTQQWPAEDTDYAIYLAKRNIKKKGILEEYEKENYDFLNKKINYKWDFVIMQAKEQYRTGKERNKADRYALDCQEKAYWLVHRSPPGMNNVLDYGLDRVTNPNEVKKQTVTAVRKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLRHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIEPQETTKRSSTLPFMRRHLRSSPSPVILRQLEEEEKAREAANTVDITQPGQHLAPSPHLAVYTGTCVPPSPSSPFSPSCRSPRKPFASPSRFIRRPSIAICPSPSRVALEGSSGLEPKGEASWSGANSGPSVTENREPSADHSRPQPRAPPKARAALSLGRFLRRGCLASPVFARLSPKCPSVSHGKVQPLGDMGQQLPRLKPKKVANFFQIKMEMPTDSGTCLMDSDDPRAGESGDQTTEKEVICPWESLAEGKAG DIP protein O54828 original sequence version: 70 72F1652D7D59EB05 h2b1m_mouse Histone H2B type 1-M H2bc14 H2B 291B Hist1h2bm protein protein mouse Mus musculus Mouse MPEPTKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK FAE8378A44BE7028 hira_mouse Protein HIRA Hira Tuple1 TUP1-like enhancer of split protein 1 protein protein mouse Mus musculus Mouse MKLLKPTWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQQLDQKNATTRETSSASSVTGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSSSLAGTMLSSPSGQQLLPLDSSTPSFGASKPCTEPVAATSARPTGESVSKDSMNATSTPAASSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPSLTSVIPTAVERLKEQNLVKELRSRELESSSDSDEKVHLAKPSSLSKRKLELEVETVEKKKKGRPRKDSRLLPMSLSVQSPAALSTEKEAMCLSAPALALKLPIPGPQRAFTLQVSSDPSMYIEVENEVTTVGGIRLSRLKCNREGKEWETVLSSRVLTAAGSCDVVCVACEKRMLSVFSTCGRRLLPPILLPSPISTLHCTGPYVMALTAAATLSVWDVHRQVVVVKEESLHSILSGSDMTVSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRNSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICKDLLGPVHCSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK 2D84294D45B7A967 h4_mouse Histone H4 H4c11 H4c12 H4c14 H4c2 H4c3 H4c4 H4c6 H4c8 H4c9 H4f16 Hist1h4a Hist4h4 Hist1h4b Hist1h4c Hist1h4d Hist1h4f Hist1h4h Hist1h4i Hist1h4j Hist1h4k Hist2h4a Hist2h4 Hist1h4m H4-53 H4-12 H4c1 protein protein mouse Mus musculus Mouse MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG DIP protein P62806 original sequence version: 108 A9E5DFD3F8B97598 rbbp4_mouse Histone-binding protein RBBP4 Rbbp4 Rbap48 Retinoblastoma-binding protein 4 Retinoblastoma-binding protein p48 Chromatin assembly factor 1 subunit C Chromatin assembly factor I p48 subunit Nucleosome-remodeling factor subunit RBAP48 protein protein mouse Mus musculus Mouse MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS DIP protein Q60972 original sequence version: 141 DIP protein Q60972 original sequence version: 117 DIP protein Q60972 original sequence version: 115 B71E2D55A444C360 q71lx8_mouse Hsp90ab1 Hsp84b Hspcb protein protein mouse Mus musculus Mouse MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKEDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPSAAVPDEIPPLEGDEDASRMEEVD CE323E81CE173ECB h3_3 2 10 unspecified role unspecified role prey prey 41 unspecified role unspecified role prey prey 24 unspecified role unspecified role prey prey 33 unspecified role unspecified role prey prey 26 unspecified role unspecified role prey prey 56 unspecified role unspecified role prey prey 54 unspecified role unspecified role prey prey 8 unspecified role unspecified role prey prey 44 unspecified role unspecified role prey prey 50 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey 52 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey 36 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 31 unspecified role unspecified role prey prey 14 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 43 unspecified role unspecified role prey prey 22 unspecified role unspecified role prey prey 9 unspecified role unspecified role prey prey 53 unspecified role unspecified role prey prey 30 unspecified role unspecified role prey prey 20 unspecified role unspecified role prey prey 32 unspecified role unspecified role prey prey 40 unspecified role unspecified role prey prey 55 unspecified role unspecified role prey prey 39 unspecified role unspecified role prey prey 51 unspecified role unspecified role prey prey 45 unspecified role unspecified role prey prey 29 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Fig 6A and Table S4. entered YFP as tag for baits rather than GFP. An interaction between H3.3 and hnRNPG-T and Macf1 was only observed in hira -/- cells. Interactions were not observed in hira -/- cells between H3.3 and (hira), Dnmt3a, Ssrp1, RGS9 and FACTp140. The identification of factors that might mediate specific Hira-independent localization of H3.3 showed that (in addition to Hira), Atrx and Daxx are proteins that specifically associate with H3.3. The participant EBI-2658123(Q9DAE2) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later. h3_2 2 41 unspecified role unspecified role prey prey 10 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey 16 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 36 unspecified role unspecified role prey prey 32 unspecified role unspecified role prey prey 8 unspecified role unspecified role prey prey 56 unspecified role unspecified role prey prey 9 unspecified role unspecified role prey prey 43 unspecified role unspecified role prey prey 14 unspecified role unspecified role prey prey 55 unspecified role unspecified role prey prey 50 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey 24 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 20 unspecified role unspecified role prey prey 26 unspecified role unspecified role prey prey 54 unspecified role unspecified role prey prey 52 unspecified role unspecified role prey prey 31 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 39 unspecified role unspecified role prey prey 44 unspecified role unspecified role prey prey association association Fig 6A and Table S4. For H3.2 (unlike H3.3), no interactions with hnRNPG-T, Macf1, (hira), Dnmt3a, Ssrp1, RGS9 and FACTp140 were observed in any cell type. h3_1 2 41 unspecified role unspecified role prey prey 10 unspecified role unspecified role prey prey 36 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey 14 unspecified role unspecified role prey prey 52 unspecified role unspecified role prey prey 31 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 39 unspecified role unspecified role prey prey 44 unspecified role unspecified role prey prey 9 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 43 unspecified role unspecified role prey prey 32 unspecified role unspecified role prey prey 26 unspecified role unspecified role prey prey 20 unspecified role unspecified role prey prey 56 unspecified role unspecified role prey prey 54 unspecified role unspecified role prey prey 50 unspecified role unspecified role prey prey 55 unspecified role unspecified role prey prey 27 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 8 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey 24 unspecified role unspecified role prey prey physical association physical association Fig 6A and Table S4. For H3.1 and H3.2 (but unlike H3.3), no interactions with hnRNPG-T, Macf1, (hira), Dnmt3a, Ssrp1, RGS9 and FACTp140 were observed in any cell type. h3_3-1 7 45 unspecified role unspecified role prey prey 29 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 53 unspecified role unspecified role prey prey physical association physical association Fig 6B and S6A. results are the same for both figures (6B and S6B) so I have not mentioned the tags. (there is also a good chance the same photo has been printed twice? - both images are identical in every respect....Also both GFP and EYFP tags are mentioned relating to fig S6B.) Atrx and Daxx association with H3.3 is specific and Hira independent. Sorry - I think I meant that Figs 6B and S6A are identical. I have altered the figure legend above, to reflect this. S6B is a whole cell lysate not an IP. h3_3_human 4 19 unspecified role unspecified role prey prey 38 unspecified role unspecified role prey prey 48 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range c terminus flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range physical association physical association Atrx and Daxx association with H3.3 is specific and Hira independent and conserved in Mouse and Human cells. Fig 6E. h3_3_telomere 3 21 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 42 unspecified role unspecified role prey prey association association Fig 7B. Atrx, but not Hira, is specifically required for H3.3 enrichment at telomeres. Histone H3.3 binds to a telomere (TTAGGG)Xn repeat array probe. Hira -/-, Atrx-null and Atrx-flox ES cells were used, H3.3 enrichment being the greatest in Hira -/- cells (> X10). h3_3_telomere-1 5 42 unspecified role unspecified role neutral component neutral component 21 unspecified role unspecified role neutral component neutral component c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range colocalization colocalization Fig 7C. Atrx, but not Hira, is specifically required for H3.3 enrichment at telomeres.H3.3 colocalization with telomeres is lost in Atrxnull ESCs, but maintained in Hira -/- ESCs. I have copied what the paper says to the comment, but I cannot see any co-localisation of anything here (I cannot see much red, full-stop). h3_3_telomere-3 6 42 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range lys9me3 n6me3+lys N6,N6,N6-trimethyl-L-lysine (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation epsilon-trimethyllysine N-trimethylation (of lysine) N6Me3+Lys Trimethyl tri-Methylation certain certain sequence position certain certain certain sequence position certain association association Fig S7F. H3.3 associates with telomeres in Atrx-flox and Atrx-null ESCs. ChIP of H3K4me3 and H3K9me3 does not show a significant difference in telomeric enrichment between Atrxflox and Atrxnull ESCs. Dot for Atrx Null with H3.3-EYFP is much less intense than for Atrs-flox cells, though still present.(experimental error?) h3_3_zfpm2 3 18 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range association association Fig 2G. H3.3 is enriched around the TSS, but not into the gene body of the H3K4me3/H3K27me3 bivalent and transcriptionally repressed Zfpm2 gene. Mutation of H3.3 toward H3.2 or H3.1 abolishes this enrichment. h3_3_actb 3 21 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 49 unspecified role unspecified role prey prey association association Fig 2H and S7B. H3.3 binding is enriched in the body of active genes, but not that of repressed genes. This enrichment often extends beyond the gene body and past the transcriptional end site (TES) at highly expressed genes in ESCs. No enrichment of H3.3 binding is seen in Hira -/- ES cells. rpb1_actb-1 3 12 unspecified role unspecified role bait bait ser5 opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations certain certain sequence position certain certain certain sequence position certain 49 unspecified role unspecified role prey prey association association Fig 2H. Binding of the RPB1 subunit of RNPII to the Actin B gene mainly occurs around the TSS and post TES. The distribution of post-TES peaks of serine-5-phosphorylated RNAPII are closely colocalized with peaks of H3.3, at active genes. The CTD4H8 antibody (used here)was raised aginast RPB1 subunit of RNAPII. I have not mentioned the unphosphorylated RNAPII results as they are from another paper - if I read the image legend correctly. rpb1_gas5 3 28 unspecified role unspecified role prey prey 12 unspecified role unspecified role bait bait ser5 opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations certain certain sequence position certain certain certain sequence position certain association association Fig 2I. H3.3 and RNAPIISer5p are enriched around the TSS and into the body of the noncoding RNA gene Gas5, but less enriched in the gene body of the neighboring low expressing Zbtb37 gene in ESCs. h3_3_gas5 3 28 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range association association Fig 2I. In ESCs, H3.3 and RNAPIISer5p are enriched around the TSS, the gene body and the region after the TES, of the noncoding RNA gene Gas5, but less enriched in the gene body of the neighboring low expressing Zbtb37 gene. h3_3_nanog 3 34 unspecified role unspecified role prey prey 17 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range association association Fig S3B In ES cells H3.3 is enriched at the TSS of Nanog and slc2a3 genes and also around the intergenic and genic TFBS near the Nanog gene. H3.3-specific enrichment is lost upon mutation of H3.3B to H3.2 or H3.1S31. At the 5' and 3' regions of the Nanog gene, H3.3 enrichment is reduced but partially maintained on differentiation of ESCs to NPCs. I did not think it appropriate to make a Nucleic acid entry for something as vague as "intergenic/genic region" - most info from this Fig has been included in the comment. (it was rather difficult to know what to enter exactly, for this image...)I have added as one bait/2 prey, as the prey are on the same line of the "graph". h3_3_esrrb 3 35 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range association association Fig 3A. H3.3 is enriched in the gene body of the highly expressed pluripotency gene Esrrb in ESCs, and this enrichment is largely lost upon differentiation to NPCs. h3_3_egfr 1 46 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range lys4me1 melys methylated lysine MeLys certain certain sequence position certain certain certain sequence position certain lys36me3 n6me3+lys N6,N6,N6-trimethyl-L-lysine (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation epsilon-trimethyllysine N-trimethylation (of lysine) N6Me3+Lys Trimethyl tri-Methylation certain certain sequence position certain certain certain sequence position certain association association Fig 3B. The Egfr gene is H3K4me3/H3K27me3 bivalent and transcriptionally repressed in ESCs. Upon differentiation to NPCs, H3.3, H3K4me1, and H3K36me3 are enriched in the Egfr gene body. h3_3_ldha 1 21 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range lys4me1 melys methylated lysine MeLys certain certain sequence position certain certain certain sequence position certain lys36me3 n6me3+lys N6,N6,N6-trimethyl-L-lysine (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation epsilon-trimethyllysine N-trimethylation (of lysine) N6Me3+Lys Trimethyl tri-Methylation certain certain sequence position certain certain certain sequence position certain lys4me3 n6me3+lys N6,N6,N6-trimethyl-L-lysine (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation epsilon-trimethyllysine N-trimethylation (of lysine) N6Me3+Lys Trimethyl tri-Methylation certain certain sequence position certain certain certain sequence position certain 46 unspecified role unspecified role prey prey association association Fig 3C. H3.3, H3K4me1, and H3K36me3 are enriched in the gene body of the housekeeping gene lactate dehydrogenase A (Ldha) in both ESCs and NPCs and is not enriched in the neighboring Ldhc gene. H3K4me3 is enriched at the Ldha TSS for both ESCs and NPCs. h3_3_ldha-1 3 15 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range association association Fig 3C. H3.3, H3K4me1, and H3K36me3 are enriched in the gene body of the housekeeping gene lactate dehydrogenase A (Ldha) in both ESCs and NPCs and is not enriched in the neighboring Ldhc gene. H3K4me3 is enriched at the Ldha TSS for both ESCs and NPCs. h3_3_rps19 3 21 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 47 unspecified role unspecified role prey prey association association Fig 4G. H3.3 enrichment at the active, ribosomal-protein coding gene Rps19 is Hira dependent. h3_3-2 7 21 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 29 unspecified role unspecified role prey prey 45 unspecified role unspecified role prey prey physical association physical association Fig 6B and S6A. Atrx and Daxx association with H3.3 is specific and Hira independent as Atrx and Daxx associate with H3.3 in Hirs-/- cells. h3_3_pparg 3 37 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range association association Fig 4G. H3.3 enrichment at the repressed bivalent gene Pparg is Hira dependent. h3_3_rps19-1 3 47 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range association association Fig 4G. H3.3 enrichment at the active, ribosomal-protein coding gene Rps19 is Hira dependent.