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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>IntAct</shortLabel>
        <fullName>European Bioinformatics Institute</fullName>
        <alias type="synonym" typeAc="MI:1041">IntAct</alias>
        <alias type="synonym" typeAc="MI:1041">intact</alias>
      </names>
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      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
        <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
        <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
        <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Tissue kallikrein is required for the cardioprotective effect of Cyclosporin A in myocardial ischemia in the mouse.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="25623731" refType="primary-reference" refTypeAc="MI:0358"/>
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            <secondaryRef db="imex" dbAc="MI:0670" id="IM-24034" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Tissue kallikrein is required for the cardioprotective effect of Cyclosporin A in myocardial ischemia in the mouse.</attribute>
            <attribute name="journal" nameAc="MI:0885">Biochemical pharmacology</attribute>
            <attribute name="publication year" nameAc="MI:0886">2015</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Youcef G., Belaidi E., Waeckel L., Fazal L., Clemessy M., Vincent MP., Zadigue G., Richer C., Alhenc-Gelas F., Ovize M., Pizard A.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Cardiac - Interactions involving cardiac related proteins</attribute>
            <attribute name="dataset" nameAc="MI:0875">Affinomics - Interactions curated for the Affinomics consortium.</attribute>
            <attribute name="contact-email" nameAc="MI:0634">anne.pizard@inserm.fr</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-24034" refType="imex-primary" refTypeAc="MI:0662"/>
          <secondaryRef db="pubmed" dbAc="MI:0446" id="25623731" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="10116">
            <names>
              <shortLabel>rat-h9c2</shortLabel>
              <fullName>h9c2 rat myoblasts</fullName>
            </names>
            <cellType>
              <names>
                <shortLabel>h9c2</shortLabel>
                <fullName>h9c2 rat myoblasts</fullName>
              </names>
              <xref>
                <primaryRef db="intact" dbAc="MI:0469" id="IA:2111" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-1347877" refType="identity" refTypeAc="MI:0356"/>
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              </xref>
            </cellType>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>pla</shortLabel>
            <fullName>proximity ligation assay</fullName>
            <alias type="go synonym" typeAc="MI:0303">pELISA</alias>
            <alias type="synonym" typeAc="MI:1041">pELISA</alias>
            <alias type="synonym" typeAc="MI:1041">PLA</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0813" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218403" refType="identity" refTypeAc="MI:0356"/>
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            <secondaryRef db="pubmed" dbAc="MI:0446" id=":17072308" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>antibody detection</shortLabel>
            <fullName>identification by antibody</fullName>
            <alias type="synonym" typeAc="MI:1041">antibody detection</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0421" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608791" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Youcef G., Belaidi E., Waeckel L., Fazal L., Clemessy M., Vincent MP., Zadigue G., Richer C., Alhenc-Gelas F., Ovize M., Pizard A.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Cardiac - Interactions involving cardiac related proteins</attribute>
          <attribute name="data-processing" nameAc="MI:0633">The molecule  "VDAC" was determined to be VDAC1 from the antibody suppliers site.</attribute>
          <attribute name="contact-email" nameAc="MI:0634">anne.pizard@inserm.fr</attribute>
          <attribute name="accepted">Accepted 2015-APR-08 by ORCHARD</attribute>
          <attribute name="journal" nameAc="MI:0885">Biochemical pharmacology</attribute>
          <attribute name="publication year" nameAc="MI:0886">2015</attribute>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>ppif_rat</shortLabel>
          <fullName>Peptidyl-prolyl cis-trans isomerase F, mitochondrial</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Cyclophilin D</alias>
          <alias type="gene name" typeAc="MI:0301">Ppif</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Cyclophilin F</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Rotamase F</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P29117" version="SP_97" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOP00000014382" version="SP_166" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6454979" refType="identity" refTypeAc="MI:0356"/>
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          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOT00000014382" version="SP_166" refType="transcript"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002931" version="SP_166"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042277" version="SP_166"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043231" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046902" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003755" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070266" version="SP_166"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090324" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1902445" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1902686" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005743" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005757" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000276" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001243" version="SP_166"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002130" version="SP_166"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020892" version="SP_166"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029000" version="SP_166"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4TOT" version="SP_166"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006457" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006979" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008637" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010849" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010939" version="SP_166"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016018" version="SP_166"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_758443.1"/>
          <secondaryRef db="rgd" dbAc="MI:0483" id="628670"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10116">
          <names>
            <shortLabel>rat</shortLabel>
            <fullName>Rattus norvegicus (Rat)</fullName>
            <alias type="synonym" typeAc="MI:1041">Rat</alias>
          </names>
        </organism>
        <sequence>MLALRCGPRLLGLLSGPRSAPLLLSTTRTCSDGGARGANSSSQNPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPAFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGKTSKKIVITDCGQLS</sequence>
        <attributeList>
          <attribute name="crc64">69048482631B9FAD</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>vdac1_rat</shortLabel>
          <fullName>Voltage-dependent anion-selective channel protein 1</fullName>
          <alias type="gene name" typeAc="MI:0301">Vdac1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Outer mitochondrial membrane protein porin 1</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9Z2L0" version="SP_52" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A1L125" version="SP_52" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q3MHT8" version="SP_52" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5M944" version="SP_52" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5M972" version="SP_52" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6IN28" version="SP_52" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6P9W9" version="SP_52" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOP00000008477" version="SP_155" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-920336" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="rgd" dbAc="MI:0483" id="621575"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_112643.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOG00000006375" version="SP_155" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOT00000008477" version="SP_155" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000166" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001662" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042645" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045121" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097001" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0110099" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901526" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1903146" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000378" version="SP_155"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001925" version="SP_155"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023614" version="SP_155"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027246" version="SP_155"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR030270" version="SP_155"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q9Z2L0" version="SP_155"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-5205685" version="SP_155"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-5689880" version="SP_155"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-70268" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031966" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005253" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005262" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005741" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005757" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006820" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006851" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007268" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007270" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007612" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008021" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008308" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015288" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015485" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030855" version="SP_155"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031210" version="SP_155"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-37068N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10116">
          <names>
            <shortLabel>rat</shortLabel>
            <fullName>Rattus norvegicus (Rat)</fullName>
            <alias type="synonym" typeAc="MI:1041">Rat</alias>
          </names>
        </organism>
        <sequence>MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q9Z2L0 original sequence version: 87</attribute>
          <attribute name="crc64">D32B05B8A8D75732</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>p08934-pro_0000006697</shortLabel>
          <fullName>Bradykinin</fullName>
          <alias type="gene name" typeAc="MI:0301">Kng1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Kng</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P08934-PRO_0000006697" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10758786" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10758758" refType="chain-parent" refTypeAc="MI:0951"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10116">
          <names>
            <shortLabel>rat</shortLabel>
            <fullName>Rattus norvegicus (Rat)</fullName>
            <alias type="synonym" typeAc="MI:1041">Rat</alias>
          </names>
        </organism>
        <sequence>RPPGFSPFR</sequence>
        <attributeList>
          <attribute name="chain-seq-start">381</attribute>
          <attribute name="chain-seq-end">389</attribute>
          <attribute name="crc64">3393D775B9C86777</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>klk1_rat</shortLabel>
          <fullName>Kallikrein-1</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Gamma-NGF</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Nerve growth factor gamma chain</alias>
          <alias type="gene name synonym" typeAc="MI:0302">PS kallikrein</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Pancreatic kallikrein</alias>
          <alias type="gene name synonym" typeAc="MI:0302">RGK-1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Tissue kallikrein</alias>
          <alias type="gene name synonym" typeAc="MI:0302">True tissue kallikrein</alias>
          <alias type="gene name" typeAc="MI:0301">Ngfg</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Klk-1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Klk1</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P00758" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q68G17" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10758809" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="rgd" dbAc="MI:0483" id="3175"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-1592389"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-381426"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033116"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_113711.1"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001254"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018114"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001314"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009003"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003073" version="SP_150"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004252" version="SP_150"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030141" version="SP_150"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031638" version="SP_150"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR043504"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10116">
          <names>
            <shortLabel>rat</shortLabel>
            <fullName>Rattus norvegicus (Rat)</fullName>
            <alias type="synonym" typeAc="MI:1041">Rat</alias>
          </names>
        </organism>
        <sequence>MWFLILFLALSLGRNDAAPPVQSRVVGGYNCEMNSQPWQVAVYYFGEYLCGGVLIDPSWVITAAHCATDNYQVWLGRNNLYEDEPFAQHRLVSQSFPHPGFNQDLIWNHTRQPGDDYSNDLMLLHLSQPADITDGVKVIDLPIEEPKVGSTCLASGWGSITPDGLELSDDLQCVNIDLLSNEKCVEAHKEEVTDLMLCAGEMDGGKDTCKGDSGGPLICNGVLQGITSWGFNPCGEPKKPGIYTKLIKFTPWIKEVMKENP</sequence>
        <attributeList>
          <attribute name="crc64">F2F99C0227A7882B</attribute>
        </attributeList>
      </interactor>
      <interactor id="6">
        <names>
          <shortLabel>tom22_rat</shortLabel>
          <fullName>Mitochondrial import receptor subunit TOM22 homolog</fullName>
          <alias type="gene name" typeAc="MI:0301">Tomm22</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Translocase of outer membrane 22 kDa subunit homolog</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Tom22</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q75Q41" version="TrEMBL_13" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOP00000019323" version="SP_104" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1180634" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="rgd" dbAc="MI:0483" id="1303260"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_997679.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOG00000014058" version="SP_104" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOT00000019323" version="SP_104" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" version="SP_104"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005742" version="SP_104"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006626" version="SP_104"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008320" version="SP_104"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" version="SP_104"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" version="SP_104"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045040" version="SP_104"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051204" version="SP_104"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005683" version="SP_104"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-5205685" version="SP_104"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10116">
          <names>
            <shortLabel>rat</shortLabel>
            <fullName>Rattus norvegicus (Rat)</fullName>
            <alias type="synonym" typeAc="MI:1041">Rat</alias>
          </names>
        </organism>
        <sequence>MAAAVAAAGAGEPLSPEELVPKAEAEKAEEDLEEDDDDELDETLSERLWGLTEMFPERVRSAAGATFDLSLFVAQKMYRFSRAALWIGTTSFMILVLPVVFETEKLQMEQQQQLQQRQILLGPNTGLSGGMPGALPPLPGKI</sequence>
        <attributeList>
          <attribute name="crc64">C1259302C15CA3AB</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="7" imexId="IM-24034-1">
        <names>
          <shortLabel>kng1-vdac1-2</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-10758756" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-24034-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="8">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="9">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>proximity</shortLabel>
            <fullName>proximity</fullName>
            <alias type="synonym" typeAc="MI:1041">close-contact colocalization</alias>
            <alias type="synonym" typeAc="MI:1041">neighbourhood interaction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2364" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-26564119" refType="identity" refTypeAc="MI:0356"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">3B-1</attribute>
        </attributeList>
      </interaction>
      <interaction id="10" imexId="IM-24034-3">
        <names>
          <shortLabel>kng1-tomm22-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-10758794" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-24034-3" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="11">
            <interactorRef>6</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="12">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>proximity</shortLabel>
            <fullName>proximity</fullName>
            <alias type="synonym" typeAc="MI:1041">close-contact colocalization</alias>
            <alias type="synonym" typeAc="MI:1041">neighbourhood interaction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2364" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-26564119" refType="identity" refTypeAc="MI:0356"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">3B-2</attribute>
        </attributeList>
      </interaction>
      <interaction id="13" imexId="IM-24034-5">
        <names>
          <shortLabel>ngfg-ppif-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-10758800" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-24034-5" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="14">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="15">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>proximity</shortLabel>
            <fullName>proximity</fullName>
            <alias type="synonym" typeAc="MI:1041">close-contact colocalization</alias>
            <alias type="synonym" typeAc="MI:1041">neighbourhood interaction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2364" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-26564119" refType="identity" refTypeAc="MI:0356"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">3B-3</attribute>
        </attributeList>
      </interaction>
      <interaction id="16" imexId="IM-24034-7">
        <names>
          <shortLabel>kng1-ppif-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-10758805" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" refType="component" refTypeAc="MI:0354"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-24034-7" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="17">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="18">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>proximity</shortLabel>
            <fullName>proximity</fullName>
            <alias type="synonym" typeAc="MI:1041">close-contact colocalization</alias>
            <alias type="synonym" typeAc="MI:1041">neighbourhood interaction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2364" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-26564119" refType="identity" refTypeAc="MI:0356"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">3B-4</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>