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    <source releaseDate="2022-02-04">
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        <shortLabel>IntAct</shortLabel>
        <fullName>European Bioinformatics Institute</fullName>
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        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
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        <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
        <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
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        <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>The Drosophila DOCK family protein sponge is involved in differentiation of R7 photoreceptor cells.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="23747680" refType="primary-reference" refTypeAc="MI:0358"/>
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          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">The Drosophila DOCK family protein sponge is involved in differentiation of R7 photoreceptor cells.</attribute>
            <attribute name="journal" nameAc="MI:0885">Exp. Cell Res. (0014-4827)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2013</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Eguchi K., Yoshioka Y., Yoshida H., Morishita K., Miyata S., Hiai H., Yamaguchi M.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Affinomics - Interactions curated for the Affinomics consortium.</attribute>
            <attribute name="data-processing" nameAc="MI:0633">The protein 'Sponge' has been entered as the longer protein of the two isoforms  listed in UniProt- Q9VAS8 (2160aas)  -the sequence of B7Z0R2 is identical until aa 2000.</attribute>
            <attribute name="contact-email" nameAc="MI:0634">myamaguc@kit.ac.jp</attribute>
            <attribute name="author-announcement">18-Sep-2014: Contacted by IntAct-Help.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-23079" refType="imex-primary" refTypeAc="MI:0662"/>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="7227">
            <names>
              <shortLabel>drome-eye_imaginal_disc</shortLabel>
              <fullName>Drosophila melanogaster</fullName>
            </names>
            <tissue>
              <names>
                <shortLabel>eye_imaginal_disc</shortLabel>
                <fullName>eye imaginal disc</fullName>
              </names>
              <xref>
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            </tissue>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>pla</shortLabel>
            <fullName>proximity ligation assay</fullName>
            <alias type="go synonym" typeAc="MI:0303">pELISA</alias>
            <alias type="synonym" typeAc="MI:1041">pELISA</alias>
            <alias type="synonym" typeAc="MI:1041">PLA</alias>
          </names>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>antibody detection</shortLabel>
            <fullName>identification by antibody</fullName>
            <alias type="synonym" typeAc="MI:1041">antibody detection</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0421" refType="identity" refTypeAc="MI:0356"/>
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        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Eguchi K., Yoshioka Y., Yoshida H., Morishita K., Miyata S., Hiai H., Yamaguchi M.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Affinomics - Interactions curated for the Affinomics consortium.</attribute>
          <attribute name="data-processing" nameAc="MI:0633">The protein 'Sponge' has been entered as the longer protein of the two isoforms  listed in UniProt- Q9VAS8 (2160aas)  -the sequence of B7Z0R2 is identical until aa 2000.</attribute>
          <attribute name="contact-email" nameAc="MI:0634">myamaguc@kit.ac.jp</attribute>
          <attribute name="accepted">Accepted 2014-SEP-17 by ORCHARD</attribute>
          <attribute name="journal" nameAc="MI:0885">Exp. Cell Res. (0014-4827)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2013</attribute>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959"/>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>rap1_drome</shortLabel>
          <fullName>Ras-related protein Rap1</fullName>
          <alias type="gene name" typeAc="MI:0301">Rap1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">R</alias>
          <alias type="gene name synonym" typeAc="MI:0302">RAP</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Rap1 GTPase</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Ras-like protein 3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">ras3</alias>
          <alias type="orf name" typeAc="MI:0306">CG1956</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P08645" version="SP_91" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q2XYB6" version="SP_101" refType="secondary-ac" refTypeAc="MI:0360"/>
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        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
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          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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        </interactorType>
        <organism ncbiTaxId="7227">
          <names>
            <shortLabel>drome</shortLabel>
            <fullName>Drosophila melanogaster (Fruit fly)</fullName>
            <alias type="synonym" typeAc="MI:1041">Fruit fly</alias>
          </names>
        </organism>
        <sequence>MREYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAKAKVNVNDIFYDLVRQINKKSPEKKQKKPKKSLCVLL</sequence>
        <attributeList>
          <attribute name="crc64">9A55889B61FEDE13</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>q9vas8_drome</shortLabel>
          <alias type="gene name" typeAc="MI:0301">spg</alias>
          <alias type="orf name" typeAc="MI:0306">CG31048</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CG11754</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CG14530</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Dm Dock4</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Dmel\CG31048</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Spg</alias>
          <alias type="gene name synonym" typeAc="MI:0302">mat(3)6</alias>
          <alias type="gene name synonym" typeAc="MI:0302">mat3(6)</alias>
          <alias type="orf name" typeAc="MI:0306">Dmel_CG31048</alias>
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          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9VAS8" version="TrEMBL_38" refType="identity" refTypeAc="MI:0356"/>
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          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
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        </interactorType>
        <organism ncbiTaxId="7227">
          <names>
            <shortLabel>drome</shortLabel>
            <fullName>Drosophila melanogaster (Fruit fly)</fullName>
            <alias type="synonym" typeAc="MI:1041">Fruit fly</alias>
          </names>
        </organism>
        <sequence>MWIPSNNKYGVAIHNWHGDVRFGLALDVGDSVDIVEECKHWYRGSCPRKSRAVGLFPKTYIHIKDLSKIDPVVAECTQVLREWSEIWKRLYVDREAYKFQTLRKVMFSILESRRELLSATMTQDQTLELQMVVVSKIDWGNRKLGLDLVPREGPLAVDPHGIGIVKLYNVHVSSADNAKASSSRGTLRRKTQRKILTHHLYFCMRDFGHRIGGDDAEVYFFLYDGSHMRPLSERFLVKISKDGFSNYIERLHSNCTVFTDLGAADLNEELHLVAVVMRVGKIIQSDSIKKIEKSGTLGHGPTFRRPFGVGVLSLGDIAHFDSSLEQSSDEREYNFKLFQCEEKDFHLLPELIIKKSSGKYSPIQASQGTQGIVVSLKLLHGGLGQARQEQPMLFQGSTITRKMGFPDVIMPGDVRNDLFLNLERGEFERGGKNTGKNILVTVVVLDVAGNVLTDCLWGASGMESQPQYRSMILYHQNAPSWNEMLRLSVPIDKFSTAHVRFEFRHCSTRDKTEPKLFAFSFARLMDTGGATLGDGLHELYVYKCEDPAKLQVANYLRLQCRPRDAQAKMDCGGCFSRSSKEVFVLRSLLCSTKLTQNADLLSLLQWRTYPETIQDSLTGVLRLNDEELVKFLQDVLDALFAMFSNEEGNSTQHSGLVFHVLVSIFSLLQSNKFQHFRPVMNEYIENHFAAALVYKGLITSVEHMAVFMTKAEHPDPFQKCFGSLEYIFKLLIQSRKLFARATGGQYEDSFKRDLHSLFTALNGMLAVPSYDVIIPTQEALLNSTGVVLEQLKDTLPAPELGMLARNMLDAIPRGAPIRLIQAKLHAVKDLVSGELFHEDDSRTVVLSVACKHLRMHLSRRDELRLCAEILSEILSQLYDLQKEQREKVTNTLQHDLDSLCKNILGILIRTISIIMEGSNAVLPQLVSCLLGLLQLLDETHYKRYWDELSPNKDPRDLKEFLSKSLLVYEELLTQDWHVFPNDWLVMKLAANDVLRMSLEEFAKPLVYRFLGPQAFDSQLWWSYFSLAVAFLTQPSLQLEQYREPKRLKILHSHGDMRVLMGFQILSMWSQLGEQKLHFIPSMVGPFLEVTLVPEPALRKATLSVFYDMMQCEQAARGSFRLVESELIDKLDLLISENKGDDEYRELFSTILLEKVQVENPNWKEAGIAFIASVTRLLERLLDYRSVMQGEENRDKRMTCTVNLLNFYKNEINRKEMYLRYIYKLHNLHLQAENYTEAGFTLKLYASMLSWDRETQSFAPFDNSGQPEWQRKERLYHEILKYFDKGKCWEKGIPLCKELAHLYETRRFDYNKLSEILIQEAKFFQNILTQLRPEPEYFRVGFYGMGLPLFVRNKQFVYRGLEYERIGAFTQRLQTEFPSAQILGNNSPPDNAILNAPDQYIQISNVRPVGDAQALKTAMVPVPEKIARFYEVNDVTRFIYDRPMYKGTVDKDNEFKSLWIERTILEIASPLPGILRWYEVKQKTMQELTPVEYACEIISNAGKELSELIVQYKRDPKRNINPFSMRLQGTIDANVMGGISKYQEAFFSEQFLKSPQGAGQQANVQRLKVLILEQIQILEQALELHGQLAPSGVQPLHNRLLERFSQLKQSLSGMGRLKRQHSESIVNTPLPPLPTEQRVAPATASSSLNANAHSNYVYDLDEIYTRPGDTVRPVDPLSSYQTLSKESLSIPLEDTAAPPVPNRPRSQNFIGNGSMDSPEVPPKRQPTLNSPNAPPLPPRGITPDKRASNPLIFNDFGSGDAVGRRHSQQQQQHGQKYSVVDISYDDPEADQQPHSLPPNFQDGSGGHLSVCFAPNDFRDSGISTTSSRELNHMNLNNLSEDSSSISTITVQHREHCRISSNGSLDYNAAASMNITQRESSTSSFDVEDFPVPPPPIPPKSLAVSSNGVNFSLDEAHSPHPSTQANTTQLNHIQNPNQNHSTNSHHHLQQQQNGDGDGYSTLQHPMNGLGLPTLPPPPSAVESPMPASAIASSTSSHQHDGGTFXVTICRCHHPPDQPHQPHKPSSSTSTSDSTATDTASESTESSSSTHSMTPPPPPPPPPSSFTHLHHQMAATTHYCQDCLSSPSPPPTIITEQAQVHPTPGSTSAQPHIEHCSCGLSFSVVQDQQEQFPRLLSTRFSTLERQTDGFQVEQVSGCQHHHHHQHSPLYHLPQSSQDAHAQTDFSYAQR</sequence>
        <attributeList>
          <attribute name="crc64">6D035A9E58FEEA90</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4" imexId="IM-23079-2">
        <names>
          <shortLabel>r-spg</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-9700741" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" refType="component" refTypeAc="MI:0354"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-23079-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="6">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>proximity</shortLabel>
            <fullName>proximity</fullName>
            <alias type="synonym" typeAc="MI:1041">close-contact colocalization</alias>
            <alias type="synonym" typeAc="MI:1041">neighbourhood interaction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2364" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-26564119" refType="identity" refTypeAc="MI:0356"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">5</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>