<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2021-07-12+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0471" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-80017" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579228" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="4058652">
                <names>
                    <shortLabel>tabach-2013-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="24084807" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-26980714" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-28977" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human-melanoma</shortLabel>
                            <fullName>Human melanoma</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>melanoma</shortLabel>
                                <fullName>Melanoma </fullName>
                            </names>
                            <xref>
                                <primaryRef db="brenda" dbAc="MI:0864" id="BTO:0000848" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-1784899" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2584825" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </tissue>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Tabach Y., Golan T., Hernández-Hernández A., Messer AR., Fukuda T., Kouznetsova A., Liu JG., Lilienthal I., Levy C., Ruvkun G.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">tabach@molbio.mgh.harvard.edu,carmitlevy@post.tau.ac.il</attribute>
                    <attribute name="journal" nameAc="MI:0885">Molecular systems biology</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2013</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="4058653">
                <names>
                    <shortLabel>suh_human</shortLabel>
                    <fullName>Recombining binding protein suppressor of hairless</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">J kappa-recombination signal-binding protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RBP-J kappa</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CBF-1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Renal carcinoma antigen NY-REN-30</alias>
                    <alias typeAc="MI:0301" type="gene name">RBPJ</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">IGKJRB</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">IGKJRB1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RBPJK</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RBPSUH</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q06330" version="SP_70" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" secondary="RNA polymerase II cis-regulatory region sequence-specific DNA binding" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009912" secondary="auditory receptor cell fate commitment" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002193" secondary="MAML1-RBP-Jkappa- ICN1 complex" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2197563" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001525" secondary="angiogenesis" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060486" secondary="club cell differentiation" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007219" secondary="Notch signaling pathway" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" secondary="sequence-specific DNA binding" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0120163" secondary="negative regulation of cold-induced thermogenesis" version="SP_206"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PY8" version="SP_206"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016863662.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005248218.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6P1N3" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000512671" version="SP_206" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061314" secondary="Notch signaling involved in heart development" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045596" secondary="negative regulation of cell differentiation" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003214" secondary="cardiac left ventricle morphogenesis" version="SP_206"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_056958.3"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-33326N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003256" secondary="regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" secondary="nucleolus" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072554" secondary="blood vessel lumenization" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" secondary="chromatin" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" secondary="negative regulation of transcription by RNA polymerase II" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013508" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001756" secondary="somitogenesis" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003198" secondary="epithelial to mesenchymal transition involved in endocardial cushion formation" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2644606" version="SP_206"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011512142.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017053" secondary="transcription repressor complex" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060844" secondary="arterial endothelial cell fate commitment" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048820" secondary="hair follicle maturation" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003222" secondary="ventricular trabecula myocardium morphogenesis" version="SP_206"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000361572" version="SP_206" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" secondary="DNA-binding transcription factor activity, RNA polymerase II-specific" version="SP_206"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015351" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030216" secondary="keratinocyte differentiation" version="SP_206"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000342295" version="SP_206" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" secondary="DNA-binding transcription factor activity" version="SP_206"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR038007" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030183" secondary="B cell differentiation" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-350054" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061419" secondary="positive regulation of transcription from RNA polymerase II promoter in response to hypoxia" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000138" secondary="positive regulation of cell proliferation involved in heart morphogenesis" version="SP_206"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4DY22" version="SP_120" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001974" secondary="blood vessel remodeling" version="SP_206"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_976029.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009957" secondary="epidermal cell fate specification" version="SP_206"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000354528" version="SP_206" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_005340.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003176" secondary="aortic valve development" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" secondary="DNA binding" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2122947" version="SP_206"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016863664.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030513" secondary="positive regulation of BMP signaling pathway" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2894862" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140297" secondary="DNA-binding transcription factor binding" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061629" secondary="RNA polymerase II-specific DNA-binding transcription factor binding" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901186" secondary="positive regulation of ERBB signaling pathway" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003682" secondary="chromatin binding" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007221" secondary="positive regulation of transcription of Notch receptor target" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0021983" secondary="pituitary gland development" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060412" secondary="ventricular septum morphogenesis" version="SP_206"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016863663.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3V79" version="SP_206"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_976028.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_206"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2F8X" version="SP_206"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000168214" version="SP_206" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008285" secondary="negative regulation of cell population proliferation" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030279" secondary="negative regulation of ossification" version="SP_206"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014756" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060045" secondary="positive regulation of cardiac muscle cell proliferation" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1912408" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013695" version="SP_206"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-632552" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008967" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097101" secondary="blood vessel endothelial cell fate specification" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043011" secondary="myeloid dendritic cell differentiation" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0047485" secondary="protein N-terminus binding" version="SP_206"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR037095" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-210744" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003139" secondary="secondary heart field specification" version="SP_206"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015350" version="SP_206"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000345206" version="SP_206" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035019" secondary="somatic stem cell population maintenance" version="SP_206"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8941856" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001837" secondary="epithelial to mesenchymal transition" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901297" secondary="positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment" version="SP_206"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901189" secondary="positive regulation of ephrin receptor signaling pathway" version="SP_206"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036358" version="SP_206"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR040159" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036302" secondary="atrioventricular canal development" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003160" secondary="endocardium morphogenesis" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002437" secondary="inflammatory response to antigenic stimulus" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060716" secondary="labyrinthine layer blood vessel development" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048733" secondary="sebaceous gland development" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003177" secondary="pulmonary valve development" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" secondary="negative regulation of transcription, DNA-templated" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042742" secondary="defense response to bacterium" version="SP_206"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000423644" version="SP_206" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048505" secondary="regulation of timing of cell differentiation" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003151" secondary="outflow tract morphogenesis" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035912" secondary="dorsal aorta morphogenesis" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_206"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016863661.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5XKH9" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006959" secondary="humoral immune response" version="SP_206"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3NBN" version="SP_206"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" secondary="DNA-binding transcription activator activity, RNA polymerase II-specific" version="SP_206"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MDHTEGSPAEEPPAHAPSPGKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFFIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNASTNSTSVTSSTATVVS</sequence>
            </interactor>
            <interactor id="4058654">
                <names>
                    <shortLabel>mitf_human</shortLabel>
                    <fullName>Microphthalmia-associated transcription factor</fullName>
                    <alias typeAc="MI:0301" type="gene name">MITF</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">BHLHE32</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Class E basic helix-loop-helix protein 32</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="O75030" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016861933.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006351" secondary="transcription, DNA-templated" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000314589"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000187098" version="SP_212" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000324246"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000448226"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000295600" version="SP_212" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000494105"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000642352"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044336" secondary="canonical Wnt signaling pathway involved in negative regulation of apoptotic process" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003682" secondary="chromatin binding" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR030532" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036638" version="SP_212"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14841" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0065003" secondary="protein-containing complex assembly" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000472437"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3K197" version="SP_135" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016861937.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000239.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_937820.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" secondary="RNA polymerase II cis-regulatory region sequence-specific DNA binding" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001227" secondary="DNA-binding transcription repressor activity, RNA polymerase II-specific" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000295600"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR031867" version="SP_212"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3232118" version="SP_212"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E9PFN0" version="SP_138" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="O75030" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046983" secondary="protein dimerization activity" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000144" secondary="positive regulation of DNA-templated transcription, initiation" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045165" secondary="cell fate commitment" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_212"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011598" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000324443"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_212"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_006713.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006355" secondary="regulation of transcription, DNA-templated" version="SP_212"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005264811.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4DJL2" version="SP_138" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" secondary="DNA-binding transcription activator activity, RNA polymerase II-specific" version="SP_212"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4C7N" version="SP_212"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9P2V2" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_937801.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" secondary="DNA-binding transcription factor activity, RNA polymerase II-specific" version="SP_212"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-28974039" refType="intact-secondary"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR021802" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" secondary="negative regulation of transcription by RNA polymerase II" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000391803"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046849" secondary="bone remodeling" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" secondary="chromatin" version="SP_212"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9P2V0" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000352241" version="SP_212" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000531774"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000377880"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_937821.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043010" secondary="camera-type eye development" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000418845"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2001141" secondary="regulation of RNA biosynthetic process" version="SP_212"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9P2V1" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-3910192" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_937802.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030316" secondary="osteoclast differentiation" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045670" secondary="regulation of osteoclast differentiation" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030336" secondary="negative regulation of cell migration" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030318" secondary="melanocyte differentiation" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042127" secondary="regulation of cell population proliferation" version="SP_212"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070888" secondary="E-box binding" version="SP_212"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-59573N"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000394351"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000314557"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" secondary="regulation of transcription by RNA polymerase II" version="SP_212"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000435909"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9P2Y8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001171896.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005264812.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_212"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTACIFPTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-28977-1" id="4058655">
                <names>
                    <shortLabel>rbpjk-mitf-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-26980721" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-28977-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>4058652</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="4058656">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-26980724" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>4058653</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="4058657">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-26980723" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>4058654</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig. 7B</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
