DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ li-2016-17 plaf7 Plasmodium falciparum (isolate 3D7) 3d-em 3D electron microscopy 3D-EM electron tomog predetermined predetermined participant predetermined Li H., O'Donoghue AJ., van der Linden WA., Xie SC., Yoo E., Foe IT., Tilley L., Craik CS., da Fonseca PC., Bogyo M. DIP original experiment: DIP-268644X Nature 2016 IMEx Structure- and function-based design of Plasmodium-selective proteasome inhibitors. Li H., O'Donoghue AJ., van der Linden WA., Xie SC., Yoo E., Foe IT., Tilley L., Craik CS., da Fonseca PC., Bogyo M. Only protein-protein interactions imex curation q7k6a9_plaf7 Proteasome subunit beta PF3D7_0803800 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MTLGPVVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLHELLTRKNINNLSEKKRKEDMYTPQHYHSYVSRVFYVRKNRIDPLFNNIIIAGINSQKYDNNDDNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYARYFALTLLRDHYKDNMTEEEARILINECLRILYFRDATSSNFIQIVKVTSKGVEYEEPYILPCVLNSADYVYPSTLLPPAGCMW a0a5k1k7u1_plaf7 Proteasome subunit beta PF3D7_0518300 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MDLILYNDNLTEKKTEKENVIEHGRGFKRWYPYIDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSDIKTLHSLLQKKIQLFVLEHSHYPDIHVIARLLCVILYSRRFFPYYAFNILAGVDENNKGVLYNYDSVGSYCEATHSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGDDINFVKDAITSATERDIYTGDKTLIYVIDKMGINVNTLDLKQD q8ijt1_plaf7 Proteasome subunit beta PF3D7_1011400 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MVIASDESFMNEIDNLINDVEDERIDNDELEFCVAPVNVPRNFIKYAQTQNKKLFDFHKGTTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLGKIIKIYELRNNEKISVRAASTILSNILYQYKGYGLCCGIILSGYDHTGFNMFYVDDSGKKVEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGKVRVFHIHKNGYDKIIEGEDVFDLHYHYTNPEQKDQYVM q8ikc9_plaf7 Proteasome subunit beta PF3D7_1470900 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MDTLIGLRGNNFVVLAADTYSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEFIRKNVHLYQYQNNTDMFVKSFAFFTRKNLAYYLRRNPFEVNCLIAGYDKKDGYQLYWCDYLSNMDSVNKGAHGYGAYLVSAILDKYYHENLTVDEALDIFKLCFEELKKRFLLTQINYELRIMYDNKVETQYVTV q8i261_plaf7 Proteasome subunit beta PF3D7_0108000 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MGSIYNYNGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYEILRYRVNLYEVRQDAEMDVECFANMLSSILYSNRFSPYFVNPIVVGFKLKHYVDEEGEKKVNYEPYLTAYDLIGAKCETRDFVVNGVTSEQLFGMCESLYVKDQDENGLFETISQCLLSALDRDCISGWGAEVLVLTPEKIIKKKLKARMD q8i6t3_plaf7 Proteasome subunit beta PF3D7_1328100 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MKLEYINILKEENGGYNFDNLKRNEILKEKGVKFPQFRKTGTTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQHNVELHRLNTNTQPRVSMCVSRLTQELFKYQGYKVCAIVLGGVDVNGPQLYGIHPHGSSCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGGNVDICVITKDSYQHIRPYKEPNMRLYHLPHPTIYPKGTTPILSEKIEYIKKFISVEDA q8i0u7_plaf7 PF3D7_0931800 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MDVVNESQIKCHEEKSWDDEYDIKTPISDGTTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIKHYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYEDKFNDYNPLVENVAHITKKIIYTNNNFLSCALIFGGYDKIKKQQLYAVNLNGSIIEKHDFAVSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNITKSFVEEFTVVNTQMNFQY o77396_plaf7 PF3D7_0317000 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MAGLSAGYDLSVSTFSPDGRLYQVEYIYKSINNNNTALCLECKDGIICCCINSNMDKNKMIKKNSYNRIYHVNNNIIITYSGFDGDARNIIDRARSEANTYYYNFHTNIPLHILVNRISLYIHAYTLYWHMRPFAASIIISSFNEKDKGDIYCIEPNGACYKYSGIVIGKNKEMFKTEIEKKDYKDINVRDAIEDIYKFILTSDDHMNKNNLQNLVNFSWICKESSYEFQNIHEEILTPALNKAVEYIEKLN q8ik90_plaf7 PF3D7_1474800 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MYRNLYDTDNIIYSPEGRLYQVEYASEAIKQGTCAVAIKSKDYVVVSGLKKCISKLSFPQEKIFKIDDYIGISMSGITSDAKVLTKFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKSSKRAFGVGLMIAAYHNEPCIFETRPNGSYFEYDALSFGARSHASKTYLEKNLHLFEECSLEELILHCLKALKCSLSSESELTISNTALAVVGKNHPWQEISSLQLEEYLSKVKMDAEQEQVEENVQNEANE q8ibi3_plaf7 Proteasome subunit alpha type PF3D7_0727400 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MFSTRSEYDRGVNTFSPEGRLFQVEYALGAIKLGSTAVGICVNDGVILASERRISSTLIEKDSVEKLLSIDDHIGCAMSGLMADARTLIDYARVECNHYKFIYNENINIKSCVELISELALDFSNLSDSKRKKIMSRPFGVALLIGGVDKNGPCLWYTEPSGTNTRFSAASIGSAQEGAELLLQENYKKDMTFEQAEILALTVLRQVMEDKLSTSNVEICAIKKSDQTFYKYNTDDISRIIDVLPSPVYPTIDMTA q8idg2_plaf7 Proteasome subunit alpha type PF3D7_1353900 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MSYDRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPKTTEKLIKLDEHNCLAFAGLNADARVLVNKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTHRGGVRPFGIATLIAGFKNNKEICIYQTEPSGIYAAWKAQAIGKNAKIVQEFLEKNYQENMEQKDCIFLALKAIFEVVELSSKNVEVALLTEKDLTFIEEQEINSMVELIDQERTKNNEQNE q8idg3_plaf7 Proteasome subunit alpha type PF3D7_1353800 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MARRYDSRTTTFSPEGRLYQVEYALEAINNASITIGLITKDGVILGADKVFISKLIDKANNYEKIYKIDKHIFCGVAGLNADANILINQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIGGYDTKDGYQLYHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKNDMTLEEGLLLALKTLAKSTDTEIPKSEKIELAYLTNKDGEVYQKYLTEKEIEELIKLYTQKYIKE c6kst3_plaf7 PF3D7_0608500 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MADGEYSFSLTTFSPTGKLVQIEYALNRVSSSSPALGIRAKNGVIIATEKKSPNELIEENSIFKIQQISEHIGIVYAGMPGDFRVLLKRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQTGGVRPFGLSLLICGVDVYGYHLYQIDPSGCYFNWMATCVGKDYQNNMSFLEKRYNKDIEIEDAIHTAILTLKESYEGVLNEKNIEIGVAYDNKPFKILTQNEIKDYLIEIE q8iar3_plaf7 PF3D7_0807500 protein protein plaf7 Plasmodium falciparum (isolate 3D7) MVRPSQSMYDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQYISQDKLLDYNNITNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEFLYSNGYNVNAETLCRNICDKIQVYTQHAYMRLHACSGMIIGIDENNKPELFKFDPSGFCAGYRACVIGNKEQESISVLERLLEKRKKKIQQETIDEDIRNTTILAIEALQTILAFDLKASEIEVAIVSTKNRNFTQISEKEIDNYLTYIAERD c0h4e8_plaf7-c6kst3_plaf7-1 3289333 N/A 3289334 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289335 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289336 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289337 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289338 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289339 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289340 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289341 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289342 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289343 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289344 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289345 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289346 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) N/A 3289347 unspecified role unspecified role unspecified role unspecified role plaf7 Plasmodium falciparum (isolate 3D7) physical association physical association false false false