<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2017-01-31Z">
            <names>
                <shortLabel>UniProt</shortLabel>
                <fullName>UniProt</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0486" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-3989247" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.uniprot.org</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="2875826">
                <names>
                    <shortLabel>wang-2015-12</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="26099046" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612507" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25625" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-macrophage</shortLabel>
                            <fullName>Mus musculus macrophage</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>macrophage</shortLabel>
                                <fullName>Macrophage</fullName>
                            </names>
                            <xref>
                                <primaryRef db="brenda" dbAc="MI:0864" id="BTO:0000801" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="IA:0315" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-1951472" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-960072" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </tissue>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>fluorescence imaging</shortLabel>
                        <fullName>fluorescence microscopy</fullName>
                        <alias typeAc="MI:1041" type="synonym">fluorescence imaging</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0416" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608494" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>immunostaining</shortLabel>
                        <fullName>immunostaining</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Wang J., Sun C., Gerdes N., Liu C., Liao M., Liu J., Shi MA., He A., Zhou Y., Sukhova GK., Chen H., Cheng XW., Kuzuya M., Murohara T., Zhang J., Cheng X., Jiang M., Shull GE., Rogers S., Yang CL., Ke Q., Jelen S., Bindels R., Ellison DH., Jarolim P., Libby P., Shi GP.</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">atherosclerotic lesions from Apoe−/− mice</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">gshi@rics.bwh.harvard.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature medicine</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2015</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="2875827">
                <names>
                    <shortLabel>wang-2015-13</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="26099046" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612564" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25625" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-endothelium</shortLabel>
                            <fullName>Mus musculus</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>endothelium</shortLabel>
                                <fullName>Endothelial cells [endothelium]</fullName>
                            </names>
                            <xref>
                                <primaryRef db="brenda" dbAc="MI:0864" id="BTO:0000393" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-347335" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-4085287" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="IA:0205" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </tissue>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>fluorescence imaging</shortLabel>
                        <fullName>fluorescence microscopy</fullName>
                        <alias typeAc="MI:1041" type="synonym">fluorescence imaging</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0416" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608494" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>immunostaining</shortLabel>
                        <fullName>immunostaining</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Wang J., Sun C., Gerdes N., Liu C., Liao M., Liu J., Shi MA., He A., Zhou Y., Sukhova GK., Chen H., Cheng XW., Kuzuya M., Murohara T., Zhang J., Cheng X., Jiang M., Shull GE., Rogers S., Yang CL., Ke Q., Jelen S., Bindels R., Ellison DH., Jarolim P., Libby P., Shi GP.</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">atherosclerotic lesions from Apoe−/− mice</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">gshi@rics.bwh.harvard.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature medicine</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2015</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="2875828">
                <names>
                    <shortLabel>wang-2015-14</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="26099046" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612577" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25625" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-arterial_smooth_muscle</shortLabel>
                            <fullName>mouse</fullName>
                            <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>arterial _smooth _muscle</shortLabel>
                            </names>
                            <xref>
                                <primaryRef db="intact" dbAc="MI:0469" id="IA:3118" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="brenda" dbAc="MI:0864" id="BTO:0000087" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-13636966" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </tissue>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>fluorescence imaging</shortLabel>
                        <fullName>fluorescence microscopy</fullName>
                        <alias typeAc="MI:1041" type="synonym">fluorescence imaging</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0416" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608494" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>immunostaining</shortLabel>
                        <fullName>immunostaining</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Wang J., Sun C., Gerdes N., Liu C., Liao M., Liu J., Shi MA., He A., Zhou Y., Sukhova GK., Chen H., Cheng XW., Kuzuya M., Murohara T., Zhang J., Cheng X., Jiang M., Shull GE., Rogers S., Yang CL., Ke Q., Jelen S., Bindels R., Ellison DH., Jarolim P., Libby P., Shi GP.</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">Atherosclerotic lesions from Apoe−/− mice</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">gshi@rics.bwh.harvard.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature medicine</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2015</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="2875829">
                <names>
                    <shortLabel>wang-2015-15</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="26099046" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612590" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25625" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-macrophage</shortLabel>
                            <fullName>Mus musculus macrophage</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>macrophage</shortLabel>
                                <fullName>Macrophage</fullName>
                            </names>
                            <xref>
                                <primaryRef db="brenda" dbAc="MI:0864" id="BTO:0000801" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="IA:0315" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-1951472" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-960072" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </tissue>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Wang J., Sun C., Gerdes N., Liu C., Liao M., Liu J., Shi MA., He A., Zhou Y., Sukhova GK., Chen H., Cheng XW., Kuzuya M., Murohara T., Zhang J., Cheng X., Jiang M., Shull GE., Rogers S., Yang CL., Ke Q., Jelen S., Bindels R., Ellison DH., Jarolim P., Libby P., Shi GP.</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">Apoe−/− mice</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">gshi@rics.bwh.harvard.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature medicine</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2015</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="2875830">
                <names>
                    <shortLabel>wang-2015-16</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="26099046" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-13636951" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25625" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-endothelium</shortLabel>
                            <fullName>Mus musculus</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>endothelium</shortLabel>
                                <fullName>Endothelial cells [endothelium]</fullName>
                            </names>
                            <xref>
                                <primaryRef db="brenda" dbAc="MI:0864" id="BTO:0000393" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-347335" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-4085287" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="IA:0205" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </tissue>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>ms participant</shortLabel>
                        <fullName>Identification by mass spectrometry</fullName>
                        <alias typeAc="MI:1041" type="synonym">ms participant</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0427" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608794" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Wang J., Sun C., Gerdes N., Liu C., Liao M., Liu J., Shi MA., He A., Zhou Y., Sukhova GK., Chen H., Cheng XW., Kuzuya M., Murohara T., Zhang J., Cheng X., Jiang M., Shull GE., Rogers S., Yang CL., Ke Q., Jelen S., Bindels R., Ellison DH., Jarolim P., Libby P., Shi GP.</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">Apoe−/−Il18r−/− mice</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">gshi@rics.bwh.harvard.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature medicine</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2015</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="2875831">
                <names>
                    <shortLabel>s12a3_mouse</shortLabel>
                    <fullName>Solute carrier family 12 member 3</fullName>
                    <alias typeAc="MI:0301" type="gene name">Slc12a3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Tsc</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Thiazide-sensitive sodium-chloride cotransporter</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Na-Cl symporter</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Ncc</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P59158" version="SP_47" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006814" secondary="sodium ion transport" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055064" secondary="chloride ion homeostasis" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015378" secondary="sodium:chloride symporter activity" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_139"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="MINT-4133700" refType="intact-secondary"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018491" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008511" secondary="sodium:potassium:chloride symporter activity" version="SP_139"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004841" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990573" secondary="potassium ion import across plasma membrane" version="SP_139"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P59158" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_139"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001192240.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055078" secondary="sodium ion homeostasis" version="SP_139"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-426117" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006821" secondary="chloride transport" version="SP_139"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8366645" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000034218" version="SP_139" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000034218" version="SP_139" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015081" secondary="sodium ion transmembrane transporter activity" version="SP_139"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004842" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035725" secondary="sodium ion transmembrane transport" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031982" secondary="vesicle" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902476" secondary="chloride transmembrane transport" version="SP_139"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013612" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_139"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000031766" version="SP_139" refType="gene"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002948" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006884" secondary="cell volume homeostasis" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015379" secondary="potassium:chloride symporter activity" version="SP_139"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055075" secondary="potassium ion homeostasis" version="SP_139"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MAELPVTELPGDALCSGRFTISTLMGGDEPPPAACDSSQPSHLTHGSTLYMRTFGYNTIDVVPAYEHYANSALPGEPRKVRPTLADLHSFLKQEGSHLHALAFDGRQGRELTDGLVEDETGTNSEKSPGEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWLIILLSVMVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGFAETVRDLLQEYGTPIVDPINDIRIIGVVTVTVLLAISLAGMEWESKAQVLFFLVIMVSFANYLVGTLIPASEDKASKGFYSYHGDIFVQNLVPDWRGIDGSFFGMFSIFFPSATGILAGANISGDLKDPAVAIPKGTLMAIFWTTISYLAISATIGSCVVRDASGDVNDTMTPGPGPCEGLACGYGWNFTECSQQRSCRYGLINYYQTMSMVSAFAPLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNREPVRGYLLAYAIAVAFIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFRYYSKWAALFGAVISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNEVEDHIKNYRPQCLVLTGPPNFRPALVDFVSTFTQNLSLMICGHVLIGPGKQRVPELRLIASGHTKWLNKRKIKAFYSDVIAEDLRSGVQILMQASGLGRMKPNILVVGFKRNWQSAHPATVEDYIGVLHDAFDFNYGVCVMRMREGLNVSEALQTHTTPEALIQEEQASTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLHRKKRWGKCKIRVFVGGQINRMDEERKAIISLLSKFRLGFHEVHVLPDINQKPQAEHTKRFEDMIAPFRLNDGFKDEATVTEMRRDCPWKISDEEINKNRIKSLRQVRLSEILLDYSRDAALIILTLPIGRKGKCPSSLYMAWLETLSQDLRPPVLLIRGNQENVLTFYCQ</sequence>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="function" nameAc="MI:0613">Electrically silent transporter system. Mediates sodium and chloride reabsorption</attribute>
                </attributeList>
            </interactor>
            <interactor id="2875832">
                <names>
                    <shortLabel>il18r_mouse</shortLabel>
                    <fullName>Interleukin-18 receptor 1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Interleukin-18 receptor alpha</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CD218 antigen-like family member A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">IL1 receptor-related protein</alias>
                    <alias typeAc="MI:0301" type="gene name">Il18r1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q61098" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000556" secondary="positive regulation of T-helper 1 cell cytokine production" version="SP_169"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_169"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015621" version="SP_169"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000142070" version="SP_169" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_032391.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000085298" version="SP_169" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000103679" version="SP_169" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050135" secondary="NAD(P)+ nucleosidase activity" version="SP_169"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006495791.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035897" version="SP_169"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000195684" version="SP_169" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042008" secondary="interleukin-18 receptor activity" version="SP_169"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0120163" secondary="negative regulation of cold-induced thermogenesis" version="SP_169"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000087983" version="SP_169" refType="transcript"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003599" version="SP_169"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000157" version="SP_169"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006495793.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000026070" version="SP_169" refType="gene"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006495795.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045063" secondary="T-helper 1 cell differentiation" version="SP_169"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042007" secondary="interleukin-18 binding" version="SP_169"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007110" version="SP_169"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006495790.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061809" secondary="NAD+ nucleotidase, cyclic ADP-ribose generating" version="SP_169"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" secondary="positive regulation of interferon-gamma production" version="SP_169"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036179" version="SP_169"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045092" secondary="interleukin-18 receptor complex" version="SP_169"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901224" secondary="positive regulation of NIK/NF-kappaB signaling" version="SP_169"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_169"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006495792.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000108044" version="SP_169" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" secondary="inflammatory response" version="SP_169"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006495797.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030101" secondary="natural killer cell activation" version="SP_169"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035655" secondary="interleukin-18-mediated signaling pathway" version="SP_169"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-13612516" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MHHEELILTLCILIVKSASKSCIHRSQIHVVEGEPFYLKPCGISAPVHRNETATMRWFKGSASHEYRELNNRSSPRVTFHDHTLEFWPVEMEDEGTYISQVGNDRRNWTLNVTKRNKHSCFSDKLVTSRDVEVNKSLHITCKNPNYEELIQDTWLYKNCKEISKTPRILKDAEFGDEGYYSCVFSVHHNGTRYNITKTVNITVIEGRSKVTPAILGPKCEKVGVELGKDVELNCSASLNKDDLFYWSIRKEDSSDPNVQEDRKETTTWISEGKLHASKILRFQKITENYLNVLYNCTVANEEAIDTKSFVLVRKEIPDIPGHVFTGGVTVLVLASVAAVCIVILCVIYKVDLVLFYRRIAERDETLTDGKTYDAFVSYLKECHPENKEEYTFAVETLPRVLEKQFGYKLCIFERDVVPGGAVVEEIHSLIEKSRRLIIVLSQSYLTNGARRELESGLHEALVERKIKIILIEFTPASNITFLPPSLKLLKSYRVLKWRADSPSMNSRFWKNLVYLMPAKAVKPWREESEARSVLSAP</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-25625-1" id="2875833">
                <names>
                    <shortLabel>il18r1-slc12a3-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612547" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25625-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>2875826</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="2875834">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612549" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2875831</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="2875835">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612548" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2875832</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">2D</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-25625-2" id="2875836">
                <names>
                    <shortLabel>il18r1-slc12a3-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612571" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25625-2" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>2875827</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="2875837">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612575" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2875831</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="2875838">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612574" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2875832</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">2D</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-25625-3" id="2875839">
                <names>
                    <shortLabel>il18r1-slc12a3-3</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612584" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25625-3" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>2875828</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="2875840">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612588" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2875831</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="2875841">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612587" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2875832</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">2D</attribute>
                    <attribute name="comment" nameAc="MI:0612">Atheroslerotic lesions tissue has been analyzed</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-25625-4" id="2875842">
                <names>
                    <shortLabel>il18r1-slc12a3-4</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612598" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25625-4" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>2875829</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="2875843">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612600" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2875831</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="2875844">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-13612599" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2875832</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">2g</attribute>
                    <attribute name="agonist" nameAc="MI:0625">IL18</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-25625-5" id="2875845">
                <names>
                    <shortLabel>il18r1-slc12a3-5</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-13636958" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25625-5" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>2875830</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="2875846">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-13636962" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2875831</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="2875847">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-13636961" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2875832</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">1D</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
